Science Interviews


Tue, 5th Apr 2016

Gene of the Month - Pygopus

Kat Arney

Listen Now    Download as mp3 from the show What's in your genes?

And finally itís time for our gene of the month, and this time itís Pygopus. Named after the species of Australian legless lizards (not snakes - theyíre definitely lizards!), Pygopus was first discovered in fruit flies in 2002. Working together with genes known as Legless and Wingless, Pygopus has a range of roles in the developing fruit fly maggot, including setting up the basic body plan, guiding the development of the gut, heart and brain, along with the structures that go on to form parts of the adult fly, including the wings and - unsurprisingly given the geneís name - the legs. And itís not just flies. Versions of Pygopus have been found in other species, including humans. We have two versions of the gene, and Pygopus faults have been implicated in bowel cancers and other types of tumour too.


Subscribe Free

Related Content

Not working please enable javascript
Powered by UKfast
Genetics Society