Podcast Transcript

The Naked Scientists: Science Radio & Science Podcasts

Article from our Archive
Bacteria seeking Asylum...

Whale of a question

A giant bowhead whale caught off northern Alaska recently had a surprise in store for the fisherman who landed it – embedded in its flesh was a piece of a "bomb lance" used by whalers back in the 1880s.  And because the weapon was patented it was easy to date, confirming claims that whales can live for 130 years or more.  The find joins other "evidence" of whale longevity which has accumulated over the years, including stone harpoon tips thought to be over 100 years old.  It was handed over to scientists by native Alaskan Inupiat fisherman who, although commercial whaling is banned, are permitted to carry out a traditional subsistence whale hunt.  The meat they catch is shared amongst the residents of their villages.

17th Jun 2007


Cholera vaccine from rice

This week we have promising news for the fight against the dreadful disease cholera, because a team of scientists in Japan are developing a new vaccine against the disease using their national staple food - rice.

Cholera continues to be a huge problem across the developing world, with at least 5000 people a year, and probably a lot more, dying from the severe dehydration caused by chronic diarrhoea that is unleashed by eating food or water contaminated with Vibrio cholerae bacteria.  Fortunately it’s a disease that’s easily treated with clean fluids and antibiotics but sadly there are still millions of people in the world who don’t have access to such treatment.

Now, researchers from the University of Tokyo have genetically engineered two strains of domestic rice to contain the CTB gene, which is a major protein of cholera bacteria.  The idea is that by introducing these cholera proteins into the body it will trigger an immune response that protects against future attacks of the disease.
The scientists have rather nicely called their new rice Mucorice, because cholera is a disease of the mucosal lining of the intestine, and they’ve shown it to be effective in preventing cholera in mice.
Sadly the vaccine can’t be taken simply by eating a bowl of steamed rice, because that could give the wrong dosage, but it can easily be made into tablets that are swallowed, getting rid of the need to inject vaccines with needles which can cause other problems like secondary infections and disposal.  Another good thing about these tablets is that they don’t need to be stored in refrigerators and the rice can easily be grown in areas of the developing world where cholera is still a huge problem.
One of the really important breakthroughs with this technique is that the researchers have found a way of delivering the vaccine to the intestine – just where it’s needed – without being broken down in the harsh enzyme-laden environment of the stomach.  Rice grains survive digestion in the stomach, and even when ground up into tablets the CTB protein is stable enough to pass through the stomach unharmed. So it’s hoped that this new technique could be used to develop vaccines for other diseases of the intestine like flu, botulism and maybe even anthrax.

17th Jun 2007


Whey to go! - Scientists make edible food wrapper

Scientists at the US Agricultural Research Service in Wyndmoor, Pennsylvania, have used milk powder and glycerine to produce a water-resistant edible film that could be used to coat or package foods.
Peggy Tomasula and her colleagues have found that high-pressure carbon dioxide can be used as a solvent to extract the protein casein from milk.  Mixing this with water and glycerol and then leaving it to dry produces a water-repelling, flexible film-like material which can keep food fresh but is also completely safe to eat and unlike most sandwich packs, completely biodegradable.  It would also reassure consumers worried about chemicals leaching from plastic wrappers into foods like cheese, because there's nothing in this film that you wouldn't eat normally anyway.

17th Jun 2007


A round up of wildlife trade

For the last couple of weeks, politicians from all around the world have been meeting to talk about endangered species and to try and decide whether trade in certain species should be restricted to prevent them from becoming even more endangered.

Every year millions of wild animals and plants are traded as pets, medicines and food and in 1963 the Convention on International Trade in Endangered Species or CITES, was set up to regulate the trade of wild species between countries to help protect them from becoming extinct. 

For a long time the trade in many highly endangered species like tigers and pandas has been completely banned, while other, less endangered species can still be traded but only under strict regulations and controls.

Every two years, members of CITES meet to decide on which species should have their trade banned, which should be regulated and which are doing okay so can be traded as much as anyone wants to.

This year, around 50 species were proposed to either be added to CITES or for their level of protection to be upgraded to a full trade ban and of these there were various successes and a few failures too.

One species that has been added to the list that can’t be traded are the sawfish, a bizarre-looking type of shark with a huge long nose or rostrum covered in sharp teeth which are dried and hung on walls as marine curios and in South America the teeth are used in cock-fighting.  The trade has also been banned in the slow loris, a cute cuddly primate with huge nocturnal eyes which looks a bit like a gremlin before it gets wet.  Slow lorises live in the rainforests of Southeast Asia and are kept by some people as pets.  For both sawfish and the slow loris it is likely that other problems such as destruction of their wild habitat and pollution are more important in determining their future than just international trade, but its hoped that the publicity they will get through listing on CITES will help raise their profile so these other problems can also be tackled.

Among the CITES failures this year are two species of shark – the porbeagle and the spiny dogfish – which are threatened by global fisheries for their meat as well as their fins for Asian shark fin soup.  And you might think shark meat is not especially attractive to eat, but you could well have eaten spiny dogfish without knowing it because it is sold in fish and chip shops as huss or rock cod. 

These two species are in a terrible state with numbers declining around the world, so it’s a huge disappointment that they have not been included in CITES which would have been the first international regulation on their exploitation.

And possibly the most controversial decision made at this latest CITES meeting was to allow the one-off sale of stockpiles of Ivory from several southern African countries.  Some people think that allowing some legal trade in ivory will stimulate elephant poaching for the illegal trade which continues to be prolific especially in Zimbabwe, but on the plus side, any proceeds made from selling these ivory stock piles must be used for elephant conservation projects – and there will be no more legal trade for at least 9 years.

17th Jun 2007


What is the difference between vaccination and immunization?

What is the difference between vaccination and immunization? When can one use one over the other? Jeremiah Saringe, Canada

Immunisation and Vaccination are two words for the same thing; essentially adding a part of a bacteria, or a whole ‘dead’ bacteria to our system, so that our immune system is prepared for us contracting the illness. We actually use the term ‘vaccination’ because the cowpox virus used by Edward Jenner as a preventative treatment for small pox is called vaccinia.

June 2007


Why does nervousness make me want to pee?

Why is it that when I’m nervous before a big event I always want to go to the loo? On the day of my driving test I must have pee’d about 6 times in a very short time before I left the house! Dev, Northampton.

There are many possible reasons, but it may be that your nervous system goes into overdrive when you’re nervous. This causes your sympathetic nervous system, the flight or flight mechanism, to kick in. This can cause an increase in blood pressure, which then inspires your kidneys to produce more urine, to try to reduce the volume of blood.

June 2007


How fat would you have to be to stop a bullet?

Have you ever wondered how fat you would have to be to stop a bullet with your belly? We went to the Cavendish Laboratory to find out...

What you need

We went to the Cavendish Laboratory to discover how fat you would have to be to stop a bullet.  We used a gas gun,  which is basically a huge air rifle.  There is a chamber that is filled with high pressure helium (this is used because it is lighter than air so will expand more quickly).

The gun has a 3m long barrel which you load a small ball bearing into.  There is a valve between the chamber and the barrel which can be opened very quickly.  The gas (at about 70 atmospheres) then expands extremely rapidly forcing the bullet out of the barrel at supersonic speeds.

 

The gas chamber

The bullet

The gas chamber which is filled by high pressure helium

The bullet  - a small steel ball bearing.

A perspex tube was filled with gelatin, which is a similar density to fat, to act as the target.

 

The tube of Gelatin

Backstop

The perspex tube full of gelatin to act as a target

This was mounted in front of a backstop full of rags.

 

 

What may Happen

A bullet hitting Gelatin

 


Naked Scientists Science Radio Show Home Who are The Naked Scientists Information about Naked Scientists
Naked Scientists Podcast Ask the Naked Scientists Podcast Question of the Week Podcast
Naked Science Articles Experiments to do at Home Science Discussion Forum
Science News Stories Answers to Science Questions Interviews with Famous Scientists

Information presented on this website is the opinion of the individual contributors and does not reflect the general views of the administrators, editors, moderators, sponsors, Cambridge University or the public at large.

Click here for the Naked Scientists PODCAST

The contents of this site are © The Naked Scientists® 2000-2012. The Naked Scientists® and Naked Science® are registered trademarks.