News
A new set of trading cards from SAGE Crossroads offers a fun look at the brains behind the latest theories on aging and immortality. Each card includes information about an anti-aging research scientist, and feature Alzheimer's researchers such as Rudy Tanzi, ...
Writing in this week's edition of Nature, Eric Leroy and his colleagues have solved a thirty year puzzle about the lethal Ebola virus - where it comes from, and where it goes when it's not causing outbreaks amongst humans and primates. To track down Ebola's 'n...
Questions

How can someone extract and sequence DNA from something that's been buried for centuries?
Well it's actually extremely difficult. Cross contamination is a big problem, and so first of all you have to make sure that your sample is clean. If the person excavating it touched it, you don't want to end up extracting their DNA by accident. We bleach it to get rid of all the DNA on the outside and then have to try and find some cells inside the sample that are still whole. We then break those open and extract the DNA.

Matthew has emailed us with an addition to an answer last week.
On the 27th edition of the Naked Scientists, John from Clacton said he saw a bright flash in the sky, and wondered if it was a gamma ray burst. Our guest on the show, Mike Hobson, said it definitely couldn't be a gamma ray burst because our eyes aren't sensitive to gamma rays. However, without having seen it, he wasn't sure what it could have been. Matthew says that there are a network of satellites used for a satellite telephone system called Iridium. They're in a low Earth orbit and have large solar panels that can catch sun light and reflect it down to the Earth. They appear as a bright flash that lasts several seconds. This is a potential explanation for what John saw that night.

I've heard that there's a single origin for the emergence of Homo sapiens. Is there any scientific background to this claim?
It's pretty difficult to say exactly where we came from, but the evidence is stacking up that we came from Africa, probably about 100 000 years ago. This is based on a combination of looking at the Y-chromosome in DNA, which is the male line, and also mitochondrial DNA, which you have to inherit from your mother. There's a lot more diversity in Africa than anywhere else, and it looks like we can track the migration of humans around the world. East Africa is looking pretty good as our origin.

Is there any such thing that could erase or change DNA?
You can definitely get rid of DNA because there are enzymes which the body makes and are found in the environment called DNAase enzymes. This means that they literally eat DNA and cut it up. So you can definitely get rid of DNA. Leaving DNA in the sun can also break it down. Changing DNA is actually very different. Changing happens in all of us due to a process called mutation, in which your DNA accidentally swaps a few of the DNA letters around. These letter swaps usually get fixed by DNA repair machinery within the cell. If it's not, it can sometimes lead to cancer. However, there's not actually a technique in which you can physically change DNA, say, at a crime scene, to implicate somebody. The best way to do that is to literally sprinkle some of their DNA at the scene.
|
|
|
|