News
Barrack Obama has famously pledged to put the US at the forefront of global warming (cynics would say it already is!), so it's fitting that a US scientist has this week developed a strategy that could lock away literally billions of tonnes of CO2 per year.
Writing in this week's PNAS, Columbia Uni...
The fight against future climate change may have an unexpected ally, in the form of mushrooms living on the soils of northern Spruce forests of Alaska, Canada and Scandinavia.
Steven Allison and Kathleen Tresede from the University of California Irvine conducted experiments in Alaska and found that...
Scientists have uncovered a genetic reason why some people are prone to alcoholism.
University of Massachusetts Medical School researcher Gilles Martin and his colleagues, writing in this week's PNAS, have found that one of the components of a pore (called the BK channel) found on the surfaces of b...
The world’s most minute solar panel cells have been built and tested and one day in the not too distant future they could be used to power even tinier microscopic machines.
The solar panels were built by Xiaomei Jiang and her team of researchers from the University of South Florida in the States.
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Questions

How are blood cells made?
We put this to Professor Adrian Newland:
Adrian - Blood cells are made in the bone marrow. In the bone space - in particular in the pelvis, in the bones of the back, the ribs and the sternum. They’re made from stem cells that then incorporate protein, iron, all the building blocks of haemoglobin that then encapsulate in cells that are pushed out into the blood. Many millions of cells every day.

What role do the appendix and tonsils play?
We put this to Professor Adrian Newland:
Adrian - The gut has lots of areas of immune system throughout it to try and deal with any infections that come in through the mouth and go down into the gut. The tonsils themselves are particularly important early on in life. That is one of the reason kids and teenagers have such problems with their tonsils. They get exposed to airborne bugs. They stimulate the tonsils to develop immunities to those bugs and the tonsils get bigger and cause bouts of tonsillitis.
Helen - I had my tonsils out when I was little and it wasn’t very nice at all. Since then I’ve been absolutely fine.

Does the UK have a 'body farm'?
We put this to Professor Adrian Newland:
Adrian - Yes. I’m not aware of any body farms in the UK unless they are hidden away somewhere.
Chris - You’re not aware of any body farms in America?
Adrian - No I’m not aware of body farms in America actually. We do have a lot of tissue banks that certainly have been regulated following the human tissue act that came through. These are a very important resource if researchers want to have material to look at, either disease or to look at normal tissue. If you want to find out the cause of a particular sort of thyroid for instance, you can get them from the bank. You can get 30 samples and look at them.

Why do some drugs work against more than one disease?
We put this to Professor Adrian Newland:
Adrian - In diseases such as Wegener’s which is an autoimmune disease it’s the immune system, the lymphocytes that actually cause immune damage. CamPath just removes those whatever the disease and will deal with that.
Chris - It’ll take away the cell that is causing the disease so the disease gets better.

Why does blood not clot when it’s in a surgical drain?
We put this to Professor Adrian Newland:
Adrian - It may eventually clot but at the operation site blood gets activated so the clotting factor’s actually get stimulated and removed so the blood is able to clot and it will build up around the wound and cause damage and prevent healing. It’s sucked out.
Chris - When you say clotting factors, Adrian, what actually are they?
Adrian - They’re little cells called platelets but also chemicals within the blood called clotting factors.
Chris - How do they work?
Adrian - They work by becoming activated by raw tissue and they form a little spider’s web that brings the blood together.
Chris - And it grabs blood cells, presumably? It forms this meshwork and you don’t bleed any more. If you’ve got oozing through that just plasma and things what Thomas might have been seeing in his drain was just plasma minus these things that have already been removed?
Adrian - Yes. It might have been exudate that oozed out and was being sucked away.

How many calories do you need to replace a pint of blood?
We put this to Professor Adrian Newland:
Adrian - About 650 calories, which I’m reliably informed is 3 Mars bars.
Chris - Why would it take energy to replace blood?
Adrian - Anything that develops tissue requires energy.
Chris - So what you’re saying is you just need to put the energy back in.
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Interviews
A recent Pathology success story - the drug CamPath, also known as alemtuzumab, was developed at Cambridge University's Pathology department, and has now been shown to have positive effects in sufferers of multiple sclerosis...
We were joined by Professor Adrian Newland, president of the Royal College of Pathologists, who explained what the role of a pathologist is, told us all about National Pathology Week, and how pathologists on TV can give the wrong impression...
We go through the process of a real post mortem - working with pathologist Alison Cluroe, we find out what has to be done to determine the cause of a death.
In place of this week's Kitchen Science experiment, Ben attended a National Pathology Week event run by the Royal College of Pathologists and the Natural History Museum, simulating an outbreak of plague in Central London. Would you know how to contain an outbreak before it becomes an epidemic?...
QotW
If the human race were to become extinct, how long before all traces of our existence were to disappear?
Arun Pandyan asked the Naked Scientists:
Chris,
I listen to the podcast regularly. I live near Dallas Texas.
Love your program.
There was a ...
- Arun Pandyan - 20th Nov 08
Yep, that would be the Forensic Anthropology Facility at the Uni of Tennessee, set up by Dr Bill Bass in 1971. This body farm has provided pretty much...
- steph - 20th Nov 08
So do they know how many bodies lie here?...
- Chemistry4me - 26th Nov 08
The "Body Farm" is a human forensic anthropology research facility at the Uni. of Tennessee in Knoxville. They leave human corpses in ...
- Evan - 13th Dec 08
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