Science Podcasts

Naked Genetics episode

Fri, 14th Mar 2014

DNA damage and repair

DNA repair (c) Tom Ellenberger

Every second your DNA is under assault - not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We’ll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. 

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In this edition of Naked Genetics

Full Transcript

  • 01:18 - What are carcinogens?

    Professor David Phillips and his team are figuring out how our DNA gets damaged, and which chemicals are responsible

  • 09:47 - How DNA gets damaged

    It’s not just things in our environment that can damage our DNA - the damage can come from within too, as Prof Dan Durocher explains.

  • 15:21 - Liver from skin

    A breakthrough from researchers in California could provide a solution to the shortage of donor organs for liver transplants in the future.

  • 16:32 - Gene for butterfly wing patterns found

    US researchers have discovered that a single gene controls the complex wing patterns in female swallowtail butterflies.

  • 17:37 - Ancient tooth microbes

    A team led by scientists from Switzerland, Denmark and the UK have unearthed a ‘microbial Pompeii’ on the teeth of 1,000 year old skeletons

  • 18:41 - DNA repair, and cancer

    Professor Steve Jackson explains how research into DNA damage and repair is leading to new treatments for cancer.

  • 24:42 - Can retinitis pigmentosa be cured?

    I have been blind for something over 40 years from a disease called Retinitis pigmentosa. It is caused by a recessive gene. It is said to be incurable. Some years ago, it was announced in the news that someone had been cured or partially cured of Retinitis pigmentosa using gen...

  • 28:05 - Gene of the Month - Gremlin

    Sharing a name with the cute but havoc-wreaking creatures in the classic 80s film, Gremlin was first discovered in frog embryos.

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