Science Podcasts

Special episode

Thu, 25th Aug 2016

See-through rats bare their brains

Mouse brain credit: Ertuerk lab (c) Ali Ertuerk - Ertuerk Lab

Scientists often study disease by examining thin sections of biological tissue under a microscope - a bit like watching a film in 2D. That’s fine for some, but an organ like the brain is really complex, with neurons crisscrossing left, right and centre. Cutting it into thin sections to study diseases like dementia means you lose all that complexity. In an ideal world then, scientists would be able to don 3D glasses and see the intact brain. Fortunately, Ali Ertuerk and his team at LMU Munich’s Acute Brain Injury Research Group have found how to make a whole rat see-through, and image its brain. Laura Brooks caught up with Ali to find out how it works…

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