Science Questions

In-the-dish vs in-the-body?

Tue, 11th Dec 2012

Listen Now    Download as mp3 from the show Unravelling Epigenetics


Andy Greaves asked:

Hi, folks. How can we be sure what happens during In Vitro studies is faithful as a representation of what happens In Vivo?


Stefanie -   This is a classic problem in experimental genetics.  You first have to be sure that your in vitro system is a very good one and you have various controls for that.  Eventually, you have to see if the same thing is happening in vivo, but itís a good way to start off.

Chris -   So, start there and then build up. Because itís generally cheaper as well.

Stefanie -   Exactly, yes.


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