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I get excess ACh when combining Alpha GPC and ALCAR on the same day, even with a low dosage of each. I experience tension in the tops of my shoulders, into the sides of my neck. A headache appears with larger or multiple doses.Neck tension and headaches are mentioned by a number of people on mind & muscle, usually related to ALCAR in some way, so I don't think they're the less common side effects in our area of concern.
Thanks Lapoisse.I think that jumping to an adrenal tumor without checking more common adrenals dysfunctions is a big statement, what labs and diagnostics would support that so far?I'm pretty confident that adrenals play a role into my POIS symptoms, in fact sex is for me a trigger that aggravates adrenal fatigue issues (low cortisol, low blood sugar, low blood pressure, low metabolism). I don't know if this can be generalized.I'm here to learn if there can be other factors in play, related or not.
Hi Andrea, Hi did the tests(blood pressure and pupil) ; both are positive for me but not that much.Also, i just talk to an endocrino MD and he thinks that if my adrenals was burnout, I'd have low cortisol wich is not the case ; However I'll have my catecholamines (blood and urine) and cortisol at 8am and 6pm tested ; I'll do it tomorow at day 2 after O, usually my worst day.I keep you informed ; Prolactin is also something that come up pretty often here ; prolactin levels are connected to orgasm and probably has an antagonist relation with dopamine : mine is always over the range but not that much and no pituary adenom on sight.Have you tried NSAIDS ? ketoprofen combined with a bit of propanolol is the only thing that help me
Hello guys, is there any way pois has something to do with the way ejaculation is accomplished? Does watching porn have anything to do with this? and if so is there someone on this forum that has pois but doesnt absolutely strictly ever watch porn?Thank you for your time,Chris
Hi urano75,It does sound like you have POIS. POIS is a strange thing, it can occur immediately with the onset of puberty (like for myself) or later in life ( like it seems for you). I can tell immediately that you have been through a rough time. Know that you are not alone in dealing with the symptoms of this and the depression it can often bring. I have had a life-altering battle with it, but things changed a lot for me after finding this community.I hope you can find some relief I didn't quite catch, have you tried to induce a niacin flush before orgasm? That's usually effective in reducing symptoms, and has helped me regain my sanity!Welcome
urano75, in my case I need to experience the flush before an "o" in order to get POIS relief. If I'm using freshly bought niacin less than a month old I can get a flush with 200mg if I haven't eaten for more than 10 hours. If the niacin is several months old I need 500mg or 600mg to get a flush after a 10 hour fast. I only experience symptom relief after a full night sleep and the relief comes in the form of increased endurance and reduced joint pain during exercise. I haven't noticed any benefit outside of increasing my ability to exercise, but I've only tried it maybe 7 times total. I wasn't taking any other vitamins at the time so I don't know if that would affect it.500mg is a lot to try the first time. Some of our members have had intensely unpleasant flushes at that level. If you try it again with a fast I think you shouldn't go over 100 or 200mg just to be safe. Also taking niacin first thing in the morning before breakfast increases the chance of flush even greater than a 10 hr fast while awake for me at least.
That's an interesting. It's much more than I take. I found pregnenolone alone was enough to give me a notable boost in mood and energy so I have not idea what all that would do to me Some of this supplementation is at cross purposes however. If you supplement methionine you're actually encouraging your body to make less methionine (probably via the SAM-e rate limiting) whereas taking methylfolate and methylcobalamin should increase the natural production and recycling of methionine. Supplementing Methionine and SAM-e made me feel good (most of the time) but I get the same effect but just exploiting the methylation cycle and taking methyl folate. BTW I had an O a few minutes ago and I feel fine. I've been trying to explain to people that I really am feeling a hell of a lot better.