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It should be safe enough as there is nothing toxic in it, assuming you neutralize the acids/bases.You would want to check the pH when you mix it with water, and adjust your proportions to get a neutral solution.Pure sodium (or Potassium) ethoxide would be very alkaline, but mix it with an acid and you should be able to neutralize it quite effectively.Of course make sure you aren't buying "denatured alcohol".If you look up the ingredients in Alka Seltzer, they are supposed to be: aspirin, citric acid, and sodium bicarbonate (baking soda). Proportions are supposed to be: Aspirin 324 mg, Sodium Bicarbonate 1916 mg, Citric Acid 1000 mg.The sodium ethoxide is a very strong base...So it may be very hygroscopic, and may not store well, especially if mixed with acetic acid.
You could do it, but you wouldn't want to get it wrong.Also, the mixed powders would be difficult to store.