Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: RD on 22/11/2007 18:13:24

Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: RD on 22/11/2007 18:13:24
I'm trying to find a photograph of "Nikolsky's sign";
it's a kite-shaped skin marking, and any information on its cause,
(specifically why it has a rhomboid form).
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: neilep on 22/11/2007 18:15:09
I'm trying to find a photograph of "Nikolsky's sign",
it's a kite-shaped skin marking, and any information on its cause.
I found this link at wikipedia

http://en.wikipedia.org/wiki/Nikolsky's_sign

and this site has  pictures http://www.uoregon.edu/~sshapiro/Pemphigus/DefinePemphigusAndAutoImmuneDisease.html

Click the PICTURES LINK !
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: RD on 22/11/2007 18:31:39
My mistake, "Nikolsky's sign" is a skin reaction like dermographia.

However Nikolsky did discover "rhomboid skin" ...

Quote
P.V. Nikolsky (1925) described rhomboid skin.
http://www.google.co.uk/search?hl=en&as_qdr=all&q=+%22P.V.+Nikolsky+%22+rhomboid&btnG=Search&meta=

So let me rephrase my question. I'm looking for a picture of "rhomboid skin",
 and an explanation to why it has this quadrilateral form.
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: neilep on 23/11/2007 18:20:44
I deleted the other duplicated thread for ya....the hunt still goes on !!
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: neilep on 23/11/2007 18:23:20
All I can find is this !!..and it's tiny !!

 [ Invalid Attachment ]
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: RD on 23/11/2007 18:43:28
Thanks for deleting the other thread.

The diamond shapes are red. I've found pics of pigs with it, (they look like they are wearing golf sweaters), but no pics of humans with it, yet.

The wrinkled back of neck above may help explain what causes skin to exhibit this quadrilateral form.
Title: I'm trying to find a photo of P.V. Nikolsky's eponymous sign
Post by: RD on 26/11/2007 17:20:52
I think the answer to the question "why are some skin markings rhomboid ?" could be "helices".

Similar sized helices with opposite chirality will produce a rhomboid pattern when superimposed.

The rhomboid markings suggest that primordial skin has formed by helical processes, like vines wrapping themselves around a tree trunk.