Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: Karen W. on 29/05/2010 19:32:27

Title: What is Hyperplastic squamous esophageal mucosa?
Post by: Karen W. on 29/05/2010 19:32:27

AND what does it mean when it has features suggestive of gastroesophageal reflux (if clinically compatible)?

Title: What is Hyperplastic squamous esophageal mucosa?
Post by: RD on 30/05/2010 01:40:27

I think this refers to increased growth of the superficial layer of mucous membrane in your gullet consistent with chronic exposure to stomach acid via “gastroesophageal reflux”: acidic stomach contents abnormally entering the {o}esophagus, (a.k.a. gullet).

This is consistent with the GERD and hiatus hernia you mentioned previously (http://www.thenakedscientists.com/forum/index.php?topic=31725.msg310124#msg310124) ...

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Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is defined as chronic symptoms or mucosal damage produced by the abnormal reflux of stomach acid to the esophagus. 

http://en.wikipedia.org/wiki/Gastroesophageal_reflux_disease

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While there are several causes of acid reflux, it does happen more frequently in the presence of hiatal hernia.

http://en.wikipedia.org/wiki/Hiatus_hernia

Title: What is Hyperplastic squamous esophageal mucosa?
Post by: Karen W. on 30/05/2010 10:11:37

Thanks RD they are some terms on my pathology reports that I am not sure about. Thank you so much...I had read all the wiki had to say about the hernia as well as the newly found Large Ulcer. I was just hoping to get the tems in laymans terms that I can understand.