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I have recently heard amazing stories of the properties of Manuka Honey http://www.manukahoney.co.uk/news.html
I understand it is an accredited treatment in many hospitals. Has anyone tried it before ? It seems to be an amazing versatile healer...from application upon the skin and for consumption
It's not cheap though...but I feel tempted to order a jar just to see....but before I do I was wondering if anyone here has tried it ?...ot at least know of it !!
Men are the same as women, just inside out !
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Never heard of it!
Karen
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I checked out the site but still have never really heard about that particular product but I do know that old naturalists have used it for years... Somewhere I have a recipe for a poultice my Grandmother used that had honey in it.. It also was for open wounds etc.
Karen
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This Manuka Honey (By The Way...you're a Honey too Karen !! [:)])....This Honey is like the Crown Jewels of Honey...it is the El Big Bosso and is unlike any other type. It seems to have incredible abilities for wound healing.
Now , I am not promoting it as a Panacea ...in fact I am not promoting it at all...but the news articles are interesting and I recently heard quite a bit on the radio about it....which originally sparked my interest.
It would be great to good a professional opinion too.
Men are the same as women, just inside out !
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Why Thank-You Kind Sir Your pretty sweet yourself!! I will keep an ear open for more of this kind of information as it could be really beneficial to keeping one healthy! Kind of a natural healing thing, don't ya think... I am all for natural remedies... especially when they make you feel so much better! Are their any chemical agents in it,,,I don't recall but believe I thought it was natural! Best go back and check it out... I wonder if it has the sticky quality raw honey has or if they have processed it in a way to prevent that.. Although I thought it was also edible, ooops yes it is for consumption also.. I just looked at your post again..! Maybe like you said , someone else might have a professional opinion that would provide a good examination of the product and perhaps a opinion from that stand point.
Sir did you look through all the pages, as I have and they have tons a stuff. If I were to think too hard I think I would like the hand cream with lavender honey!Did you happen to notice that many of the honey products have been,uh......shoot, I can't remember if they were radiated or eradiated...LOL what the heck does that mean and why would they do that? Why would it have to be radiated and would that be leaving any side or ill effects in the product to pass on to the recipient of said product? AM I just being a worry wort or what?
Karen
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Tough guys...you would take anything, gobble voraciously any unknown junk but cod liver oil!
What am I supposed to do with you...
(joking)
iko
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I've heard some about cod liver oil growing up, but did not pay too much attention!
Karen
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I made a special cod liver oil topic for you in 'Complementary Medicine'...far away from docs!
You may visit it for free (just tell them that you are my friendo, you know...it's an italian topic!)
iko
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[:)]So, Iko,
You're a doctor....do you have an opinion on Manuka Honey ?
Thank you Sir [:)]
Men are the same as women, just inside out !
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Sir I am sure I do not know what you mean by your previous post seems to be talking to me? Am I mistaken!! I have already checked out your cod liver oil post and do not understand your message!! I do not know you at all! Or know a reason to visit it for free and tell them you are my friend when I don't know you... I am sorry, please do not take offence.. as I have not got a clue and feel I should as the message in these two threads are confusing to me! Maybe You should talk with Neil Or George they may be able to help you out!
Karen
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KarenW: you probably misunderstood me. I'm sorry.
It was a joke about we italians that do everything through friends...next time I'll keep my mouth shut: you need to be mother-language for certain things (actually I knew it).
Neilep: Sorry, I don't know anything about Manuka Honey. What the heck is a 5star withdrawnmist?
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Karen, definitely a misunderstanding that's all. IKO's English even puts mine to shame !!...
I love Italy so much ...Florence is my favourite city......where do you live IKO ?
When me and the wifey were there 13 years ago we did Rome , Florence and Venice in ten days. To this day it was the best holiday we have ever had. The Italians are a beautiful and so well turned out people...and the ice cream!!.....oh my !!!!....you have not had ice cream till you've had Italian Ice cream in Italy !!!
Men are the same as women, just inside out !
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I live in Turin, in the North of Italy. Winter OLimpics2006, Fiat, Juventus...yes, Torino.
I've seen your foot, but have no idea where you live!
iko
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Neil - Very interesting. I have severe heartburn and acid reflux. It's torture. I did a little research on this and I think I'm going to order some as well. I believe I'm also going to try the oil and soap. You know - teenagers and acne. Let me know if you get some and how it worked.
Carolyn
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quote:
Originally posted by iko
Neilep: What the heck is a 5star withdrawnmist?
You've got five stars too...yours are nice and gold.
Withdrawnmist is just a title I use here. [:)]...Oh..I'm in London, UK.
Men are the same as women, just inside out !
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quote:
Originally posted by Carolyn
Neil - Very interesting. I have severe heartburn and acid reflux. It's torture. I did a little research on this and I think I'm going to order some as well. I believe I'm also going to try the oil and soap. You know - teenagers and acne. Let me know if you get some and how it worked.
Carolyn
I am seriously considering it Mam.
I suppose it's not that much to spend considering the possible benefits. I will keep you appraised...as we hope you will do too Mam. [:)]
Men are the same as women, just inside out !
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Wow thank you Iko as I am really confused lately . I humbly appologise and hope no offence was taken.. I need to relax.. and have a vacation! Really no need to keep your mouth shut Sir, it was my mistakes so please do go on in your normal manner...once again Sorry!! Yikes thank you guys alot! I feel better!
Karen
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*yawn*...I hope Manuka Honey is a good aid to sleep!!....perhaps if I whack myself over the head with a jar eh ?
Men are the same as women, just inside out !
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Still awake! Go To sleep to late!
Karen
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Nothing at all... So sorry I hate sleepless nights! I just got changed into something comfortable and haven't even approached sleep yet!
Karen
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9:25am...good night !!!
Men are the same as women, just inside out !
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You going to bed now?
Karen
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They had the lavander hand cream or some such stuff , maybe it will lull you to sleep! I like lavender! its soothing!
Karen
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oui. bonne nuit!
Karen
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quote:
Withdrawnmist is just a title I use here. ...Oh..I'm in London, UK.
Neilep
London! I spent 2 years in Du Cane rd...Hammersmith Hospital 1979-81.
Camden market, Portobello rd. and Notting hill Carneval...
I have beautiful memories of that city. We might visit it again for a weekend, who knows.
iko
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Sounds very nice! Italy that Is, I have never traveled!
Karen
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IKO.....I am so glad your time here was fun and enjoyable.
As I said in a post above...Italy was by far the best place wifey and I have been to...and I've been all over !! but Rome for driving ?...arrrggghh !! LOL..
Yes , you must visit again...we're only a few hours away as you of course must know.
We really are blessed here in Europe...so many countries so close togtether...YAYYYY !! (though some may not agree with me [:)]
Karen..I am so sorry you have not travelled......have you never even travelled within the states....it's big enough !!!
Men are the same as women, just inside out !
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Very little. I went to Idaho as an 18 year old and montana as a 20 yearold for honeymoon stayed two weeks absolutely beautiful country there not much for civilation where we were way up in the sticks no electricity! very primitive and lovely untouched if you will, lots a bears!! yikes!
oklahoma texas as a 4 year old, only remember foggy night going through toll station and sitting on grandmas lap arriving and sitting on a very very prickily cactice and being bent over my moms knee for several hours whilst she removed the needles and I wailed... I thought it was a soft hairy chair, I was 4, What can I say!been to southern cal 3 times for 1 Giants baseball game on birhtday after honeymoon and then went to frisco in semi truck with hubby to deliver a load of crab to fishermans warf and slept through drive in Los Angelos. Went as far as newport oregon and grants pass a couple trips to see my sister no touring or anything except in newport to visit my friend.. I have never taken a vacation and went anywhere to speak of!! I want to really bad!! Someday!!
Karen
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quote:
Originally posted by neilep
Karen, definitely a misunderstanding that's all. IKO's English even puts mine to shame !!...
I love Italy so much ...Florence is my favourite city......where do you live IKO ?
When me and the wifey were there 13 years ago we did Rome , Florence and Venice in ten days. To this day it was the best holiday we have ever had. The Italians are a beautiful and so well turned out people...and the ice cream!!.....oh my !!!!....you have not had ice cream till you've had Italian Ice cream in Italy !!!
Men are the same as women, just inside out !
Gelato...love it too Neil!!!
"Lo" Loretta
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Neil what is this honey about? Is it a sleep aid
"Lo" Loretta
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Hi LO (hee hee..I don't know why but saying ' Hi LO ' always makes me giggle)..
No Mam...as far as I know it's just has some incredible healing abilities, either by application on the skin or by consumption !!......hmmmmmmm...honey all over !!!!..hmmmmmm !!! *slaps own face*.....I don't think it is known as an aid to sleep !!..shame !!
Men are the same as women, just inside out !
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I don't know about ... HEE HEE it might work to bring on sleep if you use it the right way SIR!!Application on skin might work as long as removal is done with perfect fore thought....The end result could be beneficial to aiding in a nice deep sleep!!!!!LOL No Slapping allowed!!
Karen
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I found 27 citations for Manuka Honey
in PubMed database...'the right thing',
starting from 1991 and most of them quite
recent indeed. It sounds like a 'new discovery'
for western medicine. I never heard anything
about such peculiar properties and I actually
find all this 'ratherrrr' interesting.
Thank you guys!
find some hints:
Honey: a potent agent for wound healing?
Lusby PE, Coombes A, Wilkinson JM.
School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, Australia.
Although honey has been used as a traditional remedy for burns and wounds, the potential for its inclusion in mainstream medical care is not well recognized. Many studies have demonstrated that honey has antibacterial activity in vitro, and a small number of clinical case studies have shown that application of honey to severely infected cutaneous wounds is capable of clearing infection from the wound and improving tissue healing. The physicochemical properties (eg, osmotic effects and pH) of honey also aid in its antibacterial actions. Research has also indicated that honey may possess antiinflammatory activity and stimulate immune responses within a wound. The overall effect is to reduce infection and to enhance wound healing in burns, ulcers, and other cutaneous wounds. It is also known that honeys derived from particular floral sources in Australia and New Zealand (Leptospermum spp) have enhanced antibacterial activity, and these honeys have been approved for marketing as therapeutic honeys (Medihoney and Active Manuka honey). This review outlines what is known about the medical properties of honey and indicates the potential for honey to be incorporated into the management of a large number of wound types.
J Wound Ostomy Continence Nurs. 2002 Nov;29(6):295-300. Review.
Manuka honey dressing: An effective treatment for chronic wound infections.
Visavadia BG, Honeysett J, Danford MH.
Maxillofacial Unit, Royal Surrey County Hospital, Egerton Road, Guildford Surrey, UK.
The battle against methicillin-resistant Staphylococcus aureus (MRSA) wound infection is becoming more difficult as drug resistance is widespread and the incidence of MRSA in the community increases. Manuka honey dressing has long been available as a non-antibiotic treatment in the management of chronic wound infections. We have been using honey-impregnated dressings successfully in our wound care clinic and on the maxillofacial ward for over a year.
Br J Oral Maxillofac Surg. 2006 Nov 17; [Epub ahead of print]
MRSA means: methicillin-resistant Staphylococcus aureus.
...a really bad, bad, naughty BEAST!
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.idsociety.org%2FImages%2FPA%2FMRSA.jpg&hash=b499c2397da2d32c7685ee8dfb789679)(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.thesahara.fsnet.co.uk%2FMRSA%2Fstaph.jpg&hash=c62b16395033beba303ac5069126b637)(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.reactivereports.com%2F31%2Fimages%2Fmanuka.jpg&hash=70f3b23002e7240c6967d87d5f1a811b)
http://www.reactivereports.com/31/images/manuka.jpg
http://www.thesahara.fsnet.co.uk/MRSA/staph.jpg
http://www.idsociety.org/Images/PA/MRSA.jpg
I'm a bit worried, I seem to be less 'codcentrated' these days... [:o]
iko
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YAYYYY !!
IKO is great !!...does he know how well luffed he is here ?
THANK EWE for this IKO....funnily enough, I was recently thinking about this again...I still have not got round to getting some....
I would say I am one of life's great procrastinators but I'll leave it until tomorrow !!..*sorry*
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Hi Neilep!
How are your bitransplanted knees doing?
What do you need Manuka honey/oil for...
infection? Explosive rejection? I told you
that it was a cheap clinic and that
Mr. Whoknowswhat not such a top-notch...professional!
Free radical production and quenching in honeys with wound healing potential.
Henriques A, Jackson S, Cooper R, Burton N.
School of Applied Sciences, University of Wales Institute Cardiff Llandaf Campus, Western Avenue, Cardiff CF5 2YB, UK.
OBJECTIVES: Honey-impregnated wound dressings are now available on drug tariff in the UK, though the modes of action of honeys with antibacterial and wound healing properties are not entirely clear. The action of some but not all of these honeys is linked to the production of hydrogen peroxide on dilution of the honey with wound exudate. The present study investigates both free radical production and the antioxidant potential of some honeys, properties which may have a role to play in wound healing.
METHODS: Free radical production and quenching of three honey types (manuka, antibacterial but non-peroxide-producing; pasture, antibacterial peroxide-producing; commercial heat processed, non-antibacterial) was investigated by electron paramagnetic resonance (EPR) spectroscopy; quenching was also examined using a superoxide quenching assay.
RESULTS: All honeys tested had antioxidant potential, with manuka able to completely quench added radicals within 5 min of spiking. Only the peroxide-producing honey (pasture PS9) was found to form radicals on dilution.
CONCLUSIONS: The ability to modulate production and quenching of free radicals may contribute to the demonstrated ability of some honeys to help in resolving the state of inflammation typifying chronic wounds.
J Antimicrob Chemother. 2006 Oct;58(4):773-7.
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.purplesapphire.com%2Fproducts%2F613%2Fe5d96_1.jpg&hash=c8c2f21cc6a5b84b3b2b2514cbbc3e1e)
http://www.purplesapphire.com/products/613/e5d96_1.jpg
...smashing beauty from a search for 'Manuka honey' on Google Images! [;)]
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Hi Neilep!
How are your bitransplanted knees doing?
What do you need Manuka honey/oil for...
infection? Explosive rejection? I told you
that it was a cheap clinic and that
Mr. Whoknowswhat not such top-notch...professional!
Free radical production and quenching in honeys with wound healing potential.
Henriques A, Jackson S, Cooper R, Burton N.
School of Applied Sciences, University of Wales Institute Cardiff Llandaf Campus, Western Avenue, Cardiff CF5 2YB, UK.
OBJECTIVES: Honey-impregnated wound dressings are now available on drug tariff in the UK, though the modes of action of honeys with antibacterial and wound healing properties are not entirely clear. The action of some but not all of these honeys is linked to the production of hydrogen peroxide on dilution of the honey with wound exudate. The present study investigates both free radical production and the antioxidant potential of some honeys, properties which may have a role to play in wound healing.
METHODS: Free radical production and quenching of three honey types (manuka, antibacterial but non-peroxide-producing; pasture, antibacterial peroxide-producing; commercial heat processed, non-antibacterial) was investigated by electron paramagnetic resonance (EPR) spectroscopy; quenching was also examined using a superoxide quenching assay.
RESULTS: All honeys tested had antioxidant potential, with manuka able to completely quench added radicals within 5 min of spiking. Only the peroxide-producing honey (pasture PS9) was found to form radicals on dilution.
CONCLUSIONS: The ability to modulate production and quenching of free radicals may contribute to the demonstrated ability of some honeys to help in resolving the state of inflammation typifying chronic wounds.
J Antimicrob Chemother. 2006 Oct;58(4):773-7.
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.purplesapphire.com%2Fproducts%2F613%2Fe5d96_1.jpg&hash=c8c2f21cc6a5b84b3b2b2514cbbc3e1e)
http://www.purplesapphire.com/products/613/e5d96_1.jpg
...from a search for 'Manuka honey' on Google Images! [;)]
Hello Mr Iko Sir,
THANK EWE for asking about my knee !!..it is still sore !!..but oNLY when I lean on it..it feels like it's on fire !!..but it is a whole lot better than before thank you.
I was just interested in manuka as perhaps a supplement to take like my cod liver oil and garlic pills. I don't really have an ailment that requires it.
HUGS the IKO (even if he does smell of Cod !!.. [;D] [;)] [;)])..Thank you for the Manuka information .
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Bactericidal Activity of Different Types of Honey
against Clinical and Environmental Isolates of Pseudomonas aeruginosa.
Mullai V, Menon T.Department of Microbiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chen- nai, India.
Objectives: Honey has had a valued place in traditional medicine for centuries. Renewed interest in honey for various therapeutic purposes, including treatment of infected wounds, has led to the search for different types of honey with antibacterial activity. In this study, we have assessed the antibacterial activity of different types of honey (manuka honey from Australia, heather honey from the United Kingdom, and locally marketed Indian honey).
Methods: The agar dilution method was used to assess the antibacterial activity of honey against 152 isolates of Pseudomonas aeruginosa by determining minimum inhibitory concentrations.
Results and conclusions: The locally available (khadikraft) honey produced the best activity against Pseudomonas aeruginosa and was found to be better than all of the imported varieties of therapeutic honey.
J Altern Complement Med. 2007 May;13(4):439-42.
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Thanks Iko..Is this Honey local to you or the makers of the article? I am Assuming Local to India!
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Hi Karen,
Yes, it must be indian honey.
ikod
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Hey Iko, Thanks I thought that was what it was..
I know there must be some health benefit somewhere, but I am not sure I want to go grab a bunch of it and start using it! LOL Maybe some of the things look interesting... Benefits would be great!
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Hey Iko, Thanks I thought that was what it was..
I know there must be some health benefit somewhere, but I am not sure I want to go grab a bunch of it and start using it! LOL Maybe some of the things look interesting... Benefits would be great!
Talking about nutrition supplements.
Better stay more CODcentrated and leave Manuka Honey to infected wounds...that we hopefully won't ever get!
Cheers,
ikod
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LOL!! I try to stay more CODcentrated..LOL ..That poultice my gram used to make was for open wounds etc. So I know you must be right! LOL.. I need to find that recipe.. I know it worked because she used it on us many times as a child!
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I had a serious infection on my lower leg that nothing seemed to help. I took Manuka Honey,mixed with Cayenne, smeared that on a large band-aid. It took less than two weeks for the infection to completely heal. A doctor friend says that he frequetly uses table sugar on problem infections.
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I had a serious infection on my lower leg that nothing seemed to help. I took Manuka Honey,mixed with Cayenne, smeared that on a large band-aid. It took less than two weeks for the infection to completely heal. A doctor friend says that he frequetly uses table sugar on problem infections.
You did well with Manouka honey and you are certainly right about table sugar: it is highly concentrated and toxic for bacteria and fungi. No mold grows on it, in fact.
Cheers,
ikod
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That is really cool. I am glad to finally have someone actually try it! and know it worked!
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Some doctors use this natural remedy
on a routine basis and share positive
experience reporting their data:
Manuka honey dressing: An effective treatment for chronic wound infections
Visavadia BG, Honeysett J, Danford MH.
Maxillofacial Unit, Royal Surrey County Hospital, Egerton Road, Guildford Surrey, UK.
The battle against methicillin-resistant Staphylococcus aureus (MRSA) wound infection is becoming more difficult as drug resistance is widespread and the incidence of MRSA in the community increases. Manuka honey dressing has long been available as a non-antibiotic treatment in the management of chronic wound infections. We have been using honey-impregnated dressings successfully in our wound care clinic and on the maxillofacial ward for over a year.
Br J Oral Maxillofac Surg. 2006 Nov 17;
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Some doctors use this natural remedy
on a routine basis and share positive
experience reporting their data:
Manuka honey dressing: An effective treatment for chronic wound infections
Visavadia BG, Honeysett J, Danford MH.
Maxillofacial Unit, Royal Surrey County Hospital, Egerton Road, Guildford Surrey, UK.
The battle against methicillin-resistant Staphylococcus aureus (MRSA) wound infection is becoming more difficult as drug resistance is widespread and the incidence of MRSA in the community increases. Manuka honey dressing has long been available as a non-antibiotic treatment in the management of chronic wound infections. We have been using honey-impregnated dressings successfully in our wound care clinic and on the maxillofacial ward for over a year.
Br J Oral Maxillofac Surg. 2006 Nov 17;
That is very cool! I like the old remedies also!
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Manuka news:
shedding new light on the immune mechanisms that promote healing of chronically infected wounds...it should be free full-text!
http://www.jleukbio.org/cgi/rapidpdf/jlb.1106683v1
A 5.8-kDa component of manuka honey stimulates immune cells via TLR4.
Tonks AJ, Dudley E, Porter NG, Parton J, Brazier J, Smith EL, Tonks A.
Departments of *Medical Microbiology and Haematology, Cardiff University, Cardiff, United Kingdom; Biochemistry Research Group, School of Biological Sciences, School of Environment and Society, University of Wales Swansea, United Kingdom; and Crop and Food Research Ltd., Christchurch, New Zealand.
Honey is used as a therapy to aid wound healing.
Previous data indicate that honey can stimulate cytokine production from human monocytes. The present study further examines this phenomenon in manuka honey. As inflammatory cytokine production in innate immune cells is classically mediated by pattern recognition receptors in response to microorganisms, bacterial contamination of honey and the effect of blocking TLR2 and -4 on stimulatory activity were assessed. No vegetative bacteria were isolated from honey; however, bacterial spores were cultured from one-third of samples, and low levels of LPS were detected. Blocking TLR4 but not TLR2 inhibited honey-stimulated cytokine production significantly. Cytokine production did not correlate with LPS levels in honey and was not inhibited by polymyxin B. Further, the activity was reduced significantly following heat treatment, indicating that component(s) other than LPS are responsible for the stimulatory activity of manuka honey. To identify the component responsible for inducing cytokine production, honey was separated by molecular weight using microcon centrifugal filtration and fractions assessed for stimulatory activity. The active fraction was analyzed by MALDI-TOF mass spectroscopy, which demonstrated the presence of a number of components of varying molecular weights. Additional fractionation using miniaturized, reverse-phase solid-phase extraction resulted in the isolation of a 5.8-kDa component, which stimulated production of TNF-alpha via TLR4. These findings reveal mechanisms and components involved in honey stimulation of cytokine induction and could potentially lead to the development of novel therapeutics to improve wound healing for patients with acute and chronic wounds.
J Leukoc Biol. 2007 Aug 3; [Epub ahead of print]
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Iko That is really cool. Sounds like a promising study!
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Iko That is really cool. Sounds like a promising study!
Yes Karen,
and it is reaallly 'fresh news'!
It's fun to update such an old 'rediscovered' issue.
It made 5k viewers and I have to thank Neil and you
for starting this thread.
Take care
ikoD
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I think Neil Started It Iko.. He is a smart man! I will be glad for any updates!
You take care to Iko.. You've been Great!
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This is great. I know several people who could use this. My mom just had surgery and had an infection. I wonder how it would work on her.
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Hi chemtester,
welcome to this forum
and to ManukaHoney Neil planet.
Please follow indications and
instructions as close as you
can to standard clinical med.
Some doctors use this natural remedy
on a routine basis and share positive
experience reporting their data:
Manuka honey dressing: An effective treatment for chronic wound infections
Visavadia BG, Honeysett J, Danford MH.
Maxillofacial Unit, Royal Surrey County Hospital, Egerton Road, Guildford Surrey, UK.
The battle against methicillin-resistant Staphylococcus aureus (MRSA) wound infection is becoming more difficult as drug resistance is widespread and the incidence of MRSA in the community increases. Manuka honey dressing has long been available as a non-antibiotic treatment in the management of chronic wound infections. We have been using honey-impregnated dressings successfully in our wound care clinic and on the maxillofacial ward for over a year.
Br J Oral Maxillofac Surg. 2006 Nov 17;
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fa114.ac-images.myspacecdn.com%2Fimages01%2F12%2Fl_bb2cebe7831afa49b7d112d98016e7b9.jpg&hash=902e4ae629e22e7bfed83473c8a4eaba)
http://a114.ac-images.myspacecdn.com/images01/12/l_bb2cebe7831afa49b7d112d98016e7b9.jpg
Only marginal benefit reported here
in a randomized clinical trial, but we have
to point out that there was no infection:
Honey dressing versus paraffin tulle gras following toenail surgery.
McIntosh CD, Thomson CE.
Centre for Health and Social Care Research, University of Huddersfield, UK. c.mcintosh@hud.ac.uk
OBJECTIVE: Anecdotal reports suggest that certain honey dressings have a positive effect on wound healing. However, there is limited empirical evidence supporting its use.
This double-blind randomised controlled trial investigated the effect of a honey dressing on wound healing following toenail surgery with matrix phenolisation.
METHOD: Participants (n=100) were randomly assigned to receive either an active manuka honey dressing (n=52) or paraffin-impregnated tulle gras (n=48).The primary outcome was time (days) taken for complete re-epithelialisation of the nail bed.
RESULTS: Mean healing times were 40.30 days (SD 18.21) for the honey group and 39.98 days (SD 25.42) for the paraffin tulle gras group. Partial avulsion wounds healed statistically significantly faster (p=0.01) with paraffin tulle gras (19.62 days, SD 9.31) than with the honey dressing (31.76 days, SD 18.8), but no significant difference (p=0.21) was found following total avulsion when comparing honey (45.28 days, SD 18.03.) with paraffin tulle gras dressings (52.03 days, SD 21.3).
CONCLUSION: The results suggest that patients may benefit more from paraffin tulle gras dressings than honey dressings following partial toenail avulsion. No statistically significant difference was found for healing times after total toenail avulsion, although the marginal benefit of the honey dressing on these healing times warrants further investigation.
J Wound Care. 2006 Mar;15(3):133-6.
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Honeymark makes an extremely effective wound dressing. Because Manuka Honey has natural antibacterial, antimicrobial and antifungal properties, this products works well on wounds with antibiotic-resistant strains of bacteria. For more information about their First Aid Antiseptic Lotion made with Active Manuka Honey, go to
[size=07pt](**************************)
(Please remember we cannot advertise a product)[/size]
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Honeymark is a U.S.-based manufacturer of health care products that is now using Manuka Honey in creams and lotions. Their website is
[size=07pt](**************************)
(Please remember we cannot advertise a product)[/size]
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Was going to post this in the Science News Article Thread but thought it apt for here instead
Patients should ask surgeons about using honey to heal wounds
Surgeons are being advised to consider the supermarket as well as the drugs cupboard when it comes to effective wound healing, according to a research review published in the October issue of IJCP, the International Journal of Clinical Practice.
And patients who’ve undergone surgery should ask their doctors whether they should apply honey to their wounds to speed up healing and reduce infection.
“Honey is one of the oldest foods in existence and was an ancient remedy for wound healing” explains lead author Dr Fasal Rauf Khan from North West Wales NHS Trust in Bangor. “It was found in the tomb of King Tutankhamun and was still edible as it never spoils.”
Honey is enjoying a revival as more reports of its effectiveness are published, he adds.
“Researchers started to document the wound healing properties of honey in the early 20th century, but the introduction of antibiotics in 1940 temporarily halted its use.
“Now concerns about antibiotic resistance, and a renewed interest in natural remedies, has prompted a resurgence in the antimicrobial and wound healing properties of honey.
“Honey has a number of properties that make it effective against bacterial growth, including its high sugar content, low moisture content, gluconic acid – which creates an acidic environment – and hydrogen peroxide. It has also been shown to reduce inflammation and swelling.”
Researchers have also reported that applying honey can be used to reduce amputation rates among diabetes patients.
Stressing that patients should always check with their surgeon before applying any substance to post-operative wounds, Dr Khan adds that studies have found that honey offers a number of benefits.
“It can be used to sterilise infected wounds, speed up healing and impede tumours, particularly in keyhole surgery.”
Studies have suggested that honey should be applied at regular intervals, from hourly to twice daily and that wounds can become sterile in three to 10 days.
“The research suggests that honey seems to be especially indicated when wounds become infected or fail to close or heal” says Dr Khan. “It is probably even more useful for healing the wounds left by laparoscopic surgery to remove cancers.”
18 studies covering more than 60 years were included in the review. The authors also looked at other substances used for wound healing, including maggots, which were also commonly used before the introduction of antibiotics and are enjoying a revival.
The team also discovered an ancient manuscript that used wine dregs, juniper prunes and beer, but point out that that has not been tried and tested in recent years!
“Our research suggests that surgeons should seriously consider using honey for post-operative wounds and offer this to patients” concludes Dr Khan. “We would also encourage patients to ask about honey as an option, but stress that they should always follow their surgeon’s advice and not try any home remedies.”
SOURCE:EUREKALERT.ORG
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How is your Nail? [;D]
Interesting indeed, even without any vit.D or cod...
“Our research suggests that surgeons should seriously consider using honey for post-operative wounds and offer this to patients” concludes Dr Khan. “We would also encourage patients to ask about honey as an option, but stress that they should always follow their surgeon’s advice and not try any home remedies.”
This is not exactly correct, in my opinion it should be:
"follow their surgeon’s advice to try effective home remedies"
It will take time and exhaustive clinical trials to be accepted by the whole medical community.
Then we'll need a standard registered product. One human generation will pass in the meantime.
Who will be paying for those studies, the honey producers?
...the bees? [;D]
ikod
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nice posts!
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It's been 9 days since my 2nd and 3rd black widow bites. My hand has healed nicely, but the bite on my arm isn't healing. It has a knot under the bite and the entire arm is quite sore. I'm told it could take 2 weeks or longer for it to start healing. One of my friends who is nurse said to put honey on it and cover with a bandage and it should start feeling better in a few days.
I have followed her advice as of today, so I'll let you all know the results in a few days.
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It's been three days. After the first day, the knot was gone. By the second day the soreness was gone. Today, the actual bite looks better, the sore from it is almost gone.
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You didn't take any pictures! Darn!! LOL I am glad it has been healing thats great... My grandma always used some kind of honey poultice for things like that and swore by it!
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Oops, I forgot the pictures. Oh well, I'm camera shy anyway. [;)]
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LOL ... I am just hasseling ya! LOL Paul has made me a she devil with the camera.. LOL I take pictures of everything! LOL
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It's been 9 days since my 2nd and 3rd black widow bites. My hand has healed nicely, but the bite on my arm isn't healing. It has a knot under the bite and the entire arm is quite sore. I'm told it could take 2 weeks or longer for it to start healing. One of my friends who is nurse said to put honey on it and cover with a bandage and it should start feeling better in a few days.
I have followed her advice as of today, so I'll let you all know the results in a few days.
So, dear Carolyn,
How is your hand doing?
What's your experience, compared with the previous bites? [:o]
What kind of honey did you use?
No brand, just the flower!
Which dressing technique?
Just curious.
Manukod [;)]
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Hi Iko,
I'm not sure what kind of honey it was. I'll have to look when I get back from vacation. I'm sure it was just ordinary honey from the supermarket, probably Tupelo. As far as the dressing, I just put the honey on the bandage and taped it over the bite.
My hand is is fine, can't even tell I was bitten.
The last two bites were at the same time and the experience was pretty much the same as the first time. I was horribly sick. Severe abdominal pains, blurred vision, sleeplessness, nausea, muscle aches, was very weak and breathing was difficult.
I am happy to report that we've had an exterminator out to deal with our spider problem. Unfortunately, it's probably going to take a few more visits from him. He found black widows as well as brown recluse. Didn't find the poisonous ones in the living area of the house, but plenty in the garage and attic.
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My friend who has ulcers on her feet that would never heal, has been using this for about 3 months. She said the wounds are showing signs of improvement.
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Welcome to the site. Wow thats cool! I hope your friend has a full healing of her feet.
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Hi Karen,
good news from the other side of the Ocean,
and a promising website to visit! [8D]
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http://www.woundsresearch.com/article/7766
Derma Sciences Receives FDA Clearance for *****
Manuka Honey Dressing
Manuka Honey DressingDerma Sciences (Princeton, NJ), a manufacturer and marketer of advanced wound care products, has received clearance from the US Food and Drug Administration (FDA) to market and sell its ****** Active Manuka Honey Absorbent dressing.
This represents the first FDA clearance of a honey-based product for the management of wounds and burns.
Honey-based dressings are noted for their lack of toxicity, ability to be used in all phases of wound healing, as a key component in wound bed preparation regimens, and their ease of use.
Visit http://www.dermasciences.com for more information.
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Thanks IKO.. Nice link.. Its nice to see it finally approved for use. Thank you!
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Hey Iko I just saw this article on AOL too!
It is from: That's FIT
http://www.thatsfit.com/2007/12/28/honey-makes-a-comeback-as-natures-antibiotic/
Honey makes a comeback as nature's antibiotic
Posted: Dec 28th 2007 8:00AM by Adams Briscoe
Filed under: General Health, Health in the Media, Healthy Products
Before too long, we may be able to go to our local drug store and pick up honey adhesive strips. It worked for the Egyptians, why not now? That's the thinking behind Medihoney, a new product based on manuka honey which has been known to kill germs and heal wounds where traditional antibiotics fail.
Dressing wounds has been an issue for diabetes patients when drug-resistant germs keep some abrasions from healing. This is where honey comes in. Using a material based on seaweed, they soak the dressing in leptospermum honey. It will not only kill microbes, but soak up fluids and get rid of the bad smell of wounds.
Honey being used in this way has picked up in other parts of the world already. Even when the concentration is diluted ten times, this stuff can kill bacteria. Let's hope honey-based medical products hit the open market soon -- some hospitals are already using it! People with weak immune systems or persistent trauma will be able to get a lot out of this.
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...and here we go with a NEGATIVE
report, for a change.
That's clinical medicine dear friends!
Randomized clinical trial of honey-impregnated dressings for venous leg ulcers.
Jull A, Walker N, Parag V, Molan P, Rodgers A; on behalf of the Honey as Adjuvant Leg Ulcer Therapy trial collaborators.
Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand.
BACKGROUND:: The efficacy of honey as a treatment for venous ulcers has not been evaluated, despite widespread interest. This trial aimed to evaluate the safety and effectiveness of honey as a dressing for venous ulcers. METHODS:: This community-based open-label randomized trial allocated people with a venous ulcer to calcium alginate dressings impregnated with manuka honey or usual care. All participants received compression bandaging. The primary outcome was the proportion of ulcers healed after 12 weeks. Secondary outcomes were: time to healing, change in ulcer area, incidence of infection, costs per healed ulcer, adverse events and quality of life. Analysis was by intention to treat. RESULTS:: Of 368 participants, 187 were randomized to honey and 181 to usual care. At 12 weeks, 104 ulcers (55.6 per cent) in the honey-treated group and 90 (49.7 per cent) in the usual care group had healed (absolute increase 5.9 (95 per cent confidence interval (c.i.) - 4.3 to 15.7) per cent; P = 0.258). Treatment with honey was probably more expensive and associated with more adverse events (relative risk 1.3 (95 per cent c.i. 1.1 to 1.6); P = 0.013). There were no significant differences between the groups for other outcomes.
CONCLUSION:: Honey-impregnated dressings did not significantly improve venous ulcer healing at 12 weeks compared with usual care.
Registration number: ISRCTN 06161544 (http://www.controlled-trials.com). Copyright (c) 2007 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Br J Surg. 2007 Dec 28 [Epub ahead of print]
...but - apparently - there was NO infection in progress.
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Even ascorbic acid deficiency
may play a role in healing ulcers:
[Vitamin C deficiency and leg ulcers. A case control study]
[Article in French]
Lazareth I, Hubert S, Michon-Pasturel U, Priollet P.
Service de médecine vasculaire, groupe hospitalier Paris-Saint-Joseph, 185, rue Raymond-Losserand, Paris 75675 cedex 14, France. ic.lazareth@wanadoo.fr
Vitamin C is a necessary cofactor for collagen synthesis. A deficiency of vitamin C results in the breakdown of connective tissue in and around the walls of blood vessels. The disease is thus characterized by poor healing of wounds.
Chronic leg ulcers are defined as wounds that do not heal. OBJECTIVE: To investigate whether patients with chronic leg ulcers have vitamin C deficiency.
METHODS: Case control study; vitamin C was assayed in peripheral blood samples of 42 consecutive patients with chronic leg ulcers and in 37 consecutive patients without chronic leg ulcers. Patients without leg ulcers had peripheral vascular disease, or hypertension, or connective disorders. Patients with diabetes, immunodepression (cancer, HIV infection, corticosteroid therapy) and aged under 65 years were excluded. Reference range for plasma vitamin C was above 26 micromol/l (normal levels, group I), hypovitaminosis C as 6-26 micromol/l (group II) and concentrations<6 micromol/l as scurvy (group III).
RESULTS: Mean age was 77.2 years in the ulcers group and 73.8 in the control group (NS), mean weight 73.1 kg in the ulcers group and 67.5 kg in the control group (NS). Smoking was more frequent in the control group (P<0.001). Mean vitamin C levels were lower in the leg ulcers group: 23.9 vs 33.8 micromol/l (P<0.003). Normal levels of vitamin C (group I) were more frequent in the control group: 78.4 vs 50% (P<0.01). Hypovitaminosis C (group II) was more frequent in the leg ulcers group: 23.8 vs 16.2% (P<0.01). Scurvy was more frequent in the leg ulcers group: 26.2 vs 5.4% (P<0.01). C reactive protein levels were higher in the leg ulcers group: 31.8 vs 9.3 mg (P=0.002) and albumin levels were lower in the leg ulcers group: 25 vs 38 g/l (P=0.01) [retrospective data].
CONCLUSION: Patients with chronic leg ulcers have lower levels of vitamin C than patients without leg ulcers, although smoking was more frequent in patients without leg ulcers. The question is whether vitamin C deficiency is a cofactor of impaired healing or is a simple marker of poor healing? It would be interesting to conduct a randomized controlled study about treatment of chronic leg ulcers with vitamin C.
J Mal Vasc. 2007 Apr;32(2):96-9.
Vitamin A synthetic derivatives
HAVE to be in the number, of course:
The effect of short-contact topical tretinoin therapy
for foot ulcers in patients with diabetes.
Tom WL, Peng DH, Allaei A, Hsu D, Hata TR.
Division of Dermatology, Department of Medicine, University of California, San Diego, USA.
OBJECTIVE: To determine the efficacy and safety of short-contact administration of topical tretinoin on foot ulcers in patients with diabetes.
DESIGN: Randomized, double-blind, placebo-controlled trial.
SETTING: Outpatient clinic at a Veterans Affairs medical center.
PATIENTS: Twenty-four volunteers with diabetic foot ulcers but without evidence of peripheral arterial disease or infection.
INTERVENTIONS: Patients were randomized to 4 weeks of daily treatment with either topical 0.05% tretinoin solution (Retin-A) or placebo saline solution. Photographs and assessment of wound size and appearance were assessed every 2 weeks for a total of 16 weeks.
MAIN OUTCOME MEASURES: The proportion of ulcers that healed in each group and the degree of change in ulcer size. RESULTS: Twenty-two patients, with a total of 24 foot ulcers, completed the study. At the end of 16 weeks, 2 (18%) of 11 ulcers in the control group and 6 (46%) of 13 ulcers in the tretinoin treatment group healed completely. Topical tretinoin therapy significantly decreased ulcer area and depth compared with placebo treatment over the 16 weeks of the study (P < .01 for surface area; P = .02 for depth). Adverse effects mainly consisted of mild pain at the ulcer site.
CONCLUSIONS: Short-contact application of topical tretinoin improved the healing of foot ulcers in patients with diabetes. The tretinoin therapy was generally well tolerated, without serious local or systemic adverse effects.
Arch Dermatol. 2005 Nov;141(11):1373-7.
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Thanks Iko.. that is too bad! Thanks for posting the update though its good to here all of the information!
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Manuka investigators are very active these days...
and PubMed citations for "Manuka honey" rose to 32 today!
This is a fresh report about wound healing properties:
The impact of Manuka honey dressings on the surface pH of chronic wounds.
Gethin GT, Cowman S, Conroy RM.
Research Centre, Faculty of Nursing and Midwifery, Royal College of Surgeons, Ireland (RCSI), Dublin, Ireland. ggethin@eircom.net
Chronic non healing wounds have an elevated alkaline environment. The acidic pH of Manuka honey makes it a potential treatment for lowering wound pH, but the duration of effect is unknown. Lowering wound pH can potentially reduce protease activity, increase fibroblast activity and increase oxygen release consequently aiding wound healing. The aim of this study was to analyse the changes in surface pH and size of non healing ulcers following application of Manuka honey dressing after 2 weeks. The study was an open label, non randomised prospective study. Patients presenting consecutively with non healing chronic superficial ulcers, determined by aetiology and no reduction in wound size in previous 3 weeks. Single pH measurements recorded using Blueline 27 glass surface electrode and R 315 pH meter set (Reagecon/Alkem, Co. Clare Ireland). Area determined using Visitrak (Smith & Nephew, Mull, UK) digital planimetry. Apinate (Manuka honey) (Comvita, Slough, UK) applied to wounds for 2 weeks after which wounds re-evaluated. Eight males and nine females with 20 ulcers (3 bilateral) were included: venous, 50% (n = 10); mixed aetiology, 35% (n = 7); arterial, 10% (n = 2) and pressure ulcer, 5% (n = 1). Reduction in wound pH after 2 weeks was statistically significant (P < 0.001). Wounds with pH >or= 8.0 did not decrease in size and wounds with pH <or= 7.6 had a 30% decrease in size. A reduction in 0.1 pH unit was associated with an 8.1% reduction in wound size (P < 0.012). The use of Manuka honey dressings was associated with a statistically significant decrease in wound pH and a reduction in wound size. Elevated pH readings at the start were associated with minimal reduction in size. Surface wound pH measurements may contribute to objective wound assessments, but further research is necessary to determine its exact contribution.
Int Wound J. 2008 Jun;5(2):185-94.
Sunrise near Dublin
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Manuka honey is an amazing product and it really does work. However you need to be careful when buying Manuka Honey as there is lots of fake stuff. Here are a couple of pointers if you are buying Manuka honey so you don't end up spending a whole lot of money on something that does not work.
Manuka honey with high antibacterial activity is only produced in New Zealand. It is a good idea to buy it direct from this country. Better to buy a Manuka honey that has the UMF certification as this is a guarantee that it has the antibacterial level stated. Next buy a trusted brand..
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Hear a note just about honey in general.
I used to suffer from hey fever every year. Now I consume a pot of local honey at the start of the hey fever season. It seams the local honey helps me to tolerate the pollens that are active in my area. It work for me.
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Just to let people know; honey isn't all good.
http://www.nutriwatch.org/06FST/honey.html