Naked Science Forum

Life Sciences => Physiology & Medicine => Topic started by: sonia_jenifer on 23/09/2010 09:36:16

Title: What cancer therapies are available?
Post by: sonia_jenifer on 23/09/2010 09:36:16
Science has grown so much and is growing is there any medicine found for cancer?

Spam link removed - Mod
Title: Re: What cancer therapies are available?
Post by: imatfaal on 23/09/2010 10:41:00
Wow - spamming a genome sequencing service.  Bit scary that a scientific company couldn't think up a better question too!
Title: Re: What cancer therapies are available?
Post by: echochartruse on 24/09/2010 05:26:16
In Northern NSW Aust a fellow diagnosed with cancer defied science and his doctors by drinking a brew of pawpaw leaves. He is still living today.

Quote
Gold Coast based resident Stan Sheldon has for years claimed the abilities of Papaya leaves in curing cancer. A cancer survivor himself, he told the Gold Coast Bulletin how ingestion of Paw Paw leaves from the papaya tree led to a full recovery when all hope was lost.
http://www.ozcarguide.com/health/health-a-z/cancer/2361-papaya-benefits-cancer-cure
Title: Re: What cancer therapies are available?
Post by: JnA on 25/09/2010 01:28:45
hmmm one anecdote with no other information does not a cure make.

I don't doubt that there are 'beneficial' elements in papaya.. but I am always very wary of multi claims like cures cancer and helps with quick weight loss (so does cancer) improves skin quality, hair loss prevention and (I love the note at the bottom)  - Additionally, papaya has been found to be especially beneficial for women looking to enhance their breast size. A common misconception is that it would have the same effect for men, OZCAR is happy to know that this isn't one of the side effects of papaya.


Title: Re: What cancer therapies are available?
Post by: echochartruse on 25/09/2010 06:54:57
ScienceDaily (Sep. 8, 1997)
Quote
The studies show that the pawpaw compounds not only are effective in killing tumors that have proven resistant to anti-cancer agents, but also seem to have a special affinity for such resistant cells.
http://www.sciencedaily.com/releases/1997/09/970908043817.htm

Quote
Over 100 scientific papers have been published concerning the biochemistry of pawpaw substances, including significant positive results of in vitro anti-cancer studies. Most importantly, an informal and unpublished clinical trial involving 94 cancer patients, undertaken by Dr James Forsythe of the Reno Cancer Screening and Treatment Center in Nevada, showed that a significant number of terminal patients responded positively to treatment with pawpaw extract. A selection of ten positive case studies demonstrate that pawpaw extract reduced tumour markers and tumour sizes, as well as increasing longevity.

 
Quote
Papaya leaf juice is claimed to have reversed cancer in many people living on the Gold Coast
in Australia. Harold W. Tietze in his book Papaya The Medicine Tree, describes how to make .....the Gold Coast Bulletin.
“PawPaw Cancer Plea Bears Fruit". Gold coast gardeners have responded to an appeal by
cancer victims desperate to find supplies of pawpaw leaves. And the Gold Coast man who,
14 years ago, first exposed the leaves as a possible cure for cancer has been tracked down
to a Labrador (Gold Coast) nursing home. The story of how Stan Sheldon cured himself of
cancer by drinking the boiled extract of pawpaw leaves was first told in the Gold Coast
Bulletin in 1978.

Now research in the United States has given scientific support to his claim, isolating a
chemical compound in the pawpaw tree which is reported to be a million times stronger than
the strongest anti-cancer drug. Mr Sheldon, says the discovery does not surprise him..... The recipe is as follows:
Wash and partly dry several medium-size papaya leaves. Cut them up like cabbage and
place them in a saucepan with 2 quarts/ litres of water. Bring the water and leaves to the boil
and simmer without a lid until the water is reduced by half.
Strain the liquid and bottle in glass containers.
The concentrate will keep in the refrigerator for three to four days. If it becomes cloudy, it
should be discarded.

The recommended dosage in the original recipe is 3 Tablespoons/ 50ml three times a day. It
is recommended to read Papaya The Medicine Tree for the interesting stories of "incurable”
people who have used this extract to beat their cancer, and for other medicinal uses of
papaya
http://www.scribd.com/doc/9882730/Papaya-Leaf-Cure

http://www.cancerevolution.info/index.php?/cancer-therapy/Cell-energy-limitation-therapy/graviola-paw-paw-and-acetogenenins-containing-plants.html

Radium weed is used to eliminate skin cancer
Quote from:  author http://www.shaman-australis.com/forum/index.php?showtopic=21149
The Queensland Institute of Medical Research has found a natural plant-based gel known as PEP-005 that can reduce and eradicate sunspots after two days.

Dr Jim Aylward discovered the enzyme in the plant known as the radium weed.

"My mother had been keeping a weed growing for years, and she knew that it had great effects against skin cancer," he said.

Institute spokesman Dr Peter Parsons says scientists are now looking at using the enzyme to treat a variety of cancers.

These come from natural products that we can grow and use but still science insists on manufacturing pills.
Cancer = $$

Quote from:  author http://eureka.australianmuseum.net.au/D9120460-2739-11DF-B8DC005056B06558?DISPLAYENTRY=true
This team has developed a new anti-cancer drug derived from the sap of a plant called Euphorbia peplus  or radium weed in Australia. In human clinical trials the drug has been very effective in the treatment of skin cancer, one of the most common forms of cancer.

http://www.ausbiotech.org/UserFiles/File/AusBio-Magazine_March2007.pdf
Title: Re: What cancer therapies are available?
Post by: Variola on 25/09/2010 09:18:10
Quote
These come from natural products that we can grow and use but still science insists on manufacturing pills.
Cancer = $$   

No science insists on verifiable replication, if the natural products work, they will/would be researched, trialled and made into an effective
medicine. That is what science is, taking something that might work, seeing if it does work and making it into a medicine whether that is from a plant or an already known compound is irrelevant.
I for one am heartily sick of the claim that scientists are not interested in natural cures because we are driven by money.
There is no 'cure' for any cancer as yet, all we can do at best is to enable the patient to live cancer-free for as long as possible and hope it does not return. It is my personal feeling that eventually cancer will become like HIV, people live with it much longer than previously, but there is no cure.
Pharmaceutical companies may have a lot to answer for, but they are not a charity, they will only fund research that is beneficial and has some hope of improvement, they are a business and will not fund research that they feel they will lose money, that is just common sense.

If there was any solid proof, in terms of research that a plant or fruit had any verifiable affects on cancer, the research would be snapped up and funded.
Title: Re: What cancer therapies are available?
Post by: Bored chemist on 25/09/2010 11:31:58
Actually, there are cures for some forms of cancer. Surgery is an obvious one, but drugs like cisplatin can destroy some cancers completely.
Title: Re: What cancer therapies are available?
Post by: Variola on 25/09/2010 13:13:03
Actually, there are cures for some forms of cancer. Surgery is an obvious one, but drugs like cisplatin can destroy some cancers completely.

Yes but it is not a certainty the cancer will not return, that is what I would define as a cure, when we can be certain something will not return. Hence living with cancer, or living with the possibility it might return is the best we can do at present.
Title: Re: What cancer therapies are available?
Post by: Bored chemist on 25/09/2010 15:28:26
I understand that if the cancer hasn't returned after 5 years it's generally considered to be gone for good i.e. cured.
Title: Re: What cancer therapies are available?
Post by: Variola on 25/09/2010 16:38:31
I understand that if the cancer hasn't returned after 5 years it's generally considered to be gone for good i.e. cured.

That is a benchmark when the cancer is considered to be in full remission, but most consultants wont talk about it in terms of a cure because it is so unpredictable in nature.
Plus if something is a cure, it should work for a particular cancer in all or very vast majority of people, however it is just not like that.
Title: Re: What cancer therapies are available?
Post by: Bored chemist on 26/09/2010 10:21:05
Surgery generally works for the great majority of people, (provided that you can cut out all the cancer of course).

What's the difference between remission and cure? If the cancer doesn't come back then it doesn't come back.
If someone get's athletes foot, then dunks their feet in a fungicide and the infection goes away but they get the same disease again later (from another changing room floor or whatever) was that temporary remission or the cure failing or what?

It's going to be a matter of definition.
Title: Re: What cancer therapies are available?
Post by: Variola on 26/09/2010 11:55:02
Surgery is a prime example, if you can get all the cancer ad surrounding cancerous tissue, but it is impossible to tell if you have got all the cancerous cells, which is why surgery is often combined with chemotherapy. But again it depends on the type of cancer and where it is located.
Cancer is a combination of genetic mutations, the circumstances that caused that set of mutations may still be present inside the body, it may be controlled by the usual routes or it may lead to cancer again. There are so many factors involved because it is the body itself, it cannot be compared to the invasion of a pathogen, like Athlete's foot.
Most people reading this forum will have mutations in cells in their body, but they are dealt with by the body through *various routes and so cancer does not develop, that does not mean those safety measures will not fail in the future. If it does develop, and is successfully treated, and does not return for some years, that does not mean the genetic mutations are still not present in cell lineage and those safety measures will not fail again. A 'cure' is a tenuous term when it comes to cancer because it relies on the body's mechanisms as much as it does drug therapy.

*denotes this is a very complex issue so I have not gone into great reams of detail that a full explanation would require.And I would be in dager of boring the pants off people....  [:)]
Title: Re: What cancer therapies are available?
Post by: echochartruse on 26/09/2010 22:06:04
Actually, there are cures for some forms of cancer. Surgery is an obvious one, but drugs like cisplatin can destroy some cancers completely.

Yes but it is not a certainty the cancer will not return, that is what I would define as a cure, when we can be certain something will not return. Hence living with cancer, or living with the possibility it might return is the best we can do at present.
A drug has been made available for ovarian cancer and administered to all females who want to participate under the age of 25 yrs for free. or was this just a trial?
Title: Re: What cancer therapies are available?
Post by: echochartruse on 26/09/2010 22:18:16
Scientifically proven that Pawpaw compound is effective in 'killing' tumors. also proof from non scientific volunteers who has taken the boiled leaf remedy after science/doctors gave them the death sentence. Most still alive today living without cancer.

Yes but it is not a certainty the cancer will not return, that is what I would define as a cure, when we can be certain something will not return. Hence living with cancer, or living with the possibility it might return is the best we can do at present.

Radium weed is used extensively here in its natural form, due to being the region on earth with most skin cancer disease. It cures it, it does not return, I can personally assure you that. why would we want to synthesise, manufacture or commercialise the weed?
Title: Re: What cancer therapies are available?
Post by: echochartruse on 26/09/2010 22:40:20
Cancer is a combination of genetic mutations, the circumstances that caused that set of mutations may still be present inside the body, it may be controlled by the usual routes or it may lead to cancer again. There are so many factors involved because it is the body itself,

We all may carry genetics or DNA associated with cancer but never get it. It is our lifestyle, the food we eat, the place we live, etc. What science should be concerned with is finding the initiator of mutations caused to our genes and control that, which sounds more feasible to me, probably less commercially profitable though.


Quote
Natural Chemical From Sea Sponges Induces Death In Cancer Cells Via Unusual Pathway

ScienceDaily (Aug. 29, 2008) — A chemical called candidaspongiolide (CAN) inhibits protein synthesis but also kills cancer cells by triggering caspase 12-dependent programmed cell death, according to an article in the Aug. 26 online issue of the Journal of the National Cancer Institute.
http://www.sciencedaily.com/releases/2008/08/080827223119.htm
Also on this site other cancer killing treatments mentioned

Quote
Scientists Create New Process to 'Program' Cancer Cell Death. ScienceDaily (Sep. 8, 2010)
Title: Re: What cancer therapies are available?
Post by: Variola on 27/09/2010 09:25:40
Actually, there are cures for some forms of cancer. Surgery is an obvious one, but drugs like cisplatin can destroy some cancers completely.



Yes but it is not a certainty the cancer will not return, that is what I would define as a cure, when we can be certain something will not return. Hence living with cancer, or living with the possibility it might return is the best we can do at present.
A drug has been made available for ovarian cancer and administered to all females who want to participate under the age of 25 yrs for free. or was this just a trial?


I have not seen that drug, but I doubt it came with a 100% cure.
Title: Re: What cancer therapies are available?
Post by: Variola on 27/09/2010 09:29:39
Quote
We all may carry genetics or DNA associated with cancer but never get it. It is our lifestyle, the food we eat, the place we live, etc. What science should be concerned with is finding the initiator of mutations caused to our genes and control that, which sounds more feasible to me, probably less commercially profitable though.

 

Er....we already do! That is what a lot of the research funding goes into. Problem is what happens in vitro is not always what happens in vivo.
The mutations are so complex, and peoples biochemistry is so variable, it is like unravelling a large ball of wool with a JCB!
Title: Re: What cancer therapies are available?
Post by: Variola on 27/09/2010 09:32:56
Quote
Radium weed is used extensively here in its natural form, due to being the region on earth with most skin cancer disease. It cures it, it does not return, I can personally assure you that. why would we want to synthesise, manufacture or commercialise the weed?
 

To extract the active compound and analyse it's effect, thus possibly opening up the chance of it being effective against other types of cancer, and to ensure people get the correct dosage to maximise their chances of recovery.
And how do you know it does not return? Skin cancer does not restrict itself to the skin.
Title: Re: What cancer therapies are available?
Post by: echochartruse on 28/09/2010 22:44:20
Don't get me wrong. I'm all for research.
A drug has been made available for ovarian cancer and administered to all females who want to participate under the age of 25 yrs for free. or was this just a trial?

I have not seen that drug, but I doubt it came with a 100% cure.
My appology 'cervical cancer' not ovarian cancer. The injection was offered to all woman in Australia under 25yr old for Free.
http://www.smh.com.au/news/national/cancer-vaccine-not-before-2008-abbott/2006/11/10/1162661861926.html

I would hope that is had been proven to be 100% effective but it came with a warning that woman were not to stop having pap smears. Although I have known Australia to be the testing ground for various chemical, medical etc experiements, so if no other country has heard of this maybe Australians are just the 'test shop dummies' for this vaccine?!
Title: Re: What cancer therapies are available?
Post by: echochartruse on 28/09/2010 22:50:29
Radium weed is applied direct to skin cancer. You pick the weed and place the white sap directly onto the effected area. In 2-3 days it is burned off. It's been used for years here and doctors will perscribe, by telling us to go pick it and how to use it.

I'm all for experiementing and reasearching just don't know why we have to bottle it.
Title: Re: What cancer therapies are available?
Post by: Geezer on 29/09/2010 02:51:32
I would hope that is had been proven to be 100% effective but it came with a warning that woman were not to stop having pap smears. Although I have known Australia to be the testing ground for various chemical, medical etc experiements, so if no other country has heard of this maybe Australians are just the 'test shop dummies' for this vaccine?!

This is also available in the US. I don't know much about it, but I seem to recall it's an immunization against a particular virus that can lead to cervical cancer.
Title: Re: What cancer therapies are available?
Post by: echochartruse on 29/09/2010 06:10:54
yes difficult to find info on the vaccine, here's some
http://en.wikipedia.org/wiki/Cervical_cancer
Title: Re: What cancer therapies are available?
Post by: echochartruse on 29/09/2010 06:31:10
Actually, there are cures for some forms of cancer. Surgery is an obvious one, but drugs like cisplatin can destroy some cancers completely.

I've just found info on cisplatin.

Is that's why paw paw is not known to cancer patients?
With Paw paw, instead of drug companies taking the royalties for the cancer treatment, we may have to give the royalties to the farmers to grow the fruit.....Then we would have to set security fences around the perimiter of the farm, then employ security guards to transport it to the factory where it can be bottled and perscribed by doctors bought from chemists.

Quote from:  author http://204.3.196.169/cisplat/cisplat16.htm
Nearly all of the university’s royalty income comes from cisplatin and carboplatin, and nearly 20 percent of RCT revenues comes from the two drugs.2 Because of this monetary component to the lawsuit, many people—including officials at other universities having contracts with RCT,
Title: Re: What cancer therapies are available?
Post by: Bored chemist on 29/09/2010 07:03:37
Echochartreuse.
Do you know that there are at least two anti cancer drugs extracted from plants?
The pharmaceutical companies would be quite happy to make money from paw paw in the same way they make it from yew trees and the Madagascar periwinkle.

Also, there are other reasons for establishing what the active ingredient is. Of course, it helps get the dose right and that's always a good thing.
It also means they can develop derivatives with better efficiency and fewer side effects.
Title: What cancer therapies are available?
Post by: echochartruse on 30/09/2010 01:43:05
I know that there are more than two componants of natural plants that is used in manufacturing drugs and it is apparent you do too.

I'm all for researching these componants but not for engineering the plants change prior to or at all before we fully understand all the plants componants and how they effect us.
Not to the extent of distroying these plants through environment mismanagement, corporate greed etc only to promote the manufactured, processed version able to be synthisised from knowing and studying the natural componants.

Quote from:  author London, Jan 20 (ANI): In a breakthrough study, MIT researchers have successfully engineered plants to produce entirely compounds that can be used as drugs against cancer.

The researchers have genetically altered plants into create chemicals they do not naturally make. The plant-produced compounds include molecules similar to cancer drugs................According to O”Connor, the resulting alkaloids vary only slightly from the compounds the periwinkle makes naturally, but such tweaks could prove useful for improving medicines that plants already make.
http://www.thaindian.com/newsportal/health/madagascar-periwinkle-engineered-to-produce-anti-cancer-compound_100144659.html


Note the words 'similar' and 'vary only slightly' (above)

Science has the key componant in plants to treat cancer but finds a need to be able to manufacture it.

Title: What cancer therapies are available?
Post by: Bored chemist on 30/09/2010 07:01:49
The compounds used definitely differ from those grown normally.
They may "vary only slightly" but the differences are bigger than the difference between methanol and ethanol. Do you understand that "similar" chemicals can have very different effects.

There's also the fact that the plants contain other, unwanted materials which only contribute toxicity without adding effectiveness. These are removed in the purification steps so modification of the plant "before we fully understand all the plants componants and how they effect us." is a non-issue. The other components are removed.

Whether the changes in chemistry are done in the plant or in the laboratory hardly matters.
Title: What cancer therapies are available?
Post by: Variola on 30/09/2010 07:52:52
Exactly, the difference between a drug working or not can be as little as 1 amino acid.
There is also the bioavailablity of a drug to consider, and the toxicity effects, What happens on the skin can be vastly different from the effect inside the body.
This is not just about the faults of the pharmaceutical companies, of which there are many, this is about biochemistry and the body.
Title: What cancer therapies are available?
Post by: Geezer on 30/09/2010 08:44:20
Exactly

All this agreeing stuff is making me a bit nervous  [::)]

I sense an impending attack. I'm heading for the underground bunker right now.
Title: What cancer therapies are available?
Post by: Variola on 30/09/2010 17:15:33
Exactly

All this agreeing stuff is making me a bit nervous  [::)]


I sense an impending attack. I'm heading for the underground bunker right now.

Who from me or the BC??? [;)]
Title: What cancer therapies are available?
Post by: echochartruse on 30/09/2010 23:05:25
If it works why fix (synthetically manufacture) it?

Toxic substances found in various flu vaccines include:

    * Dangerous levels of mercury in the form of thimerosal, a deadly preservative that is 50 times more toxic than regular mercury
    * Ethylene glycol (antifreeze)
    * Formaldehyde – a known cancer-causing agent
    * Neomycin and streptomycin (antibiotics)
    * Aluminum -- a neurotoxin linked to Alzheimer’s disease
    * Polysorbate 80 (Tween80™) – which can cause severe allergic reactions, including anaphylaxis
    * Phenol (carbolic acid)
    * Resin and gelatin - known to cause allergic reactions
    * Triton X100 (detergent)

So every year that you get a flu shot, you are taking a risk that one or more of these substances added by science to make it easier to manufacture will cause a problem in your body.

What good is adding mercury in flu vaccine to anyone?

Here is an example of a vaccine that has been banned in Australia due to causing convulsions, allergies and death. Now America is spending $2B to engineer plants to produce the vaccine quicker, even though it has been scientifically studied to find it is as effective as a placebo. Wall street expect the returns to double.

Quote from:  author  Western Australia Times
Flu vaccination ban goes national after fever, convulsions in children] Seasonal flu vaccinations have been suspended in Australia for all children under the age of five. The suspension comes after 23 children in Western Australia were admitted to hospitals with convulsions after receiving flu injections.

Quote from:  author The Wall Street Journal reported:
“To meet anticipated demand, manufacturers are producing between 160 million and 165 million doses this year, more than ever before … The CDC is accelerating development of two new tools to speed production of vaccine … One involves optimizing seed strains of virus used to make vaccine

Quote from:  author http://www.ddw-online.com/enabling_technologies/338814/21st_century_vaccines_a_development_renaissance.html
Improved manufacturing techniques and invention of new adjuvants have greatly advanced the development of influenza vaccines, the fastest growing segment in the adult vaccine area, which is expected to generate $4 billion in sales by 2012.
One way to escape the recession OR lower populations!

So you say, it is NOT OK to take a natural, out of the garden product, as it may have an amino acid that may adversely effect us! [???] But it is OK to synthesise and add toxic additives and genetically modify the plant so science has control over what we ingest  [???]

http://organichealthadviser.com/archives/if-the-h1n1-swine-flu-vaccine-is-safe-then-why-are-so-many-people-being-hurt-by-it

Quote from:  author http://www.theflucase.com/index.php?option=com_content&view=article&id=1416%3Afifth-qswine-fluq-vaccine-death-in-sweden-vaccinations-still-go-ahead-as-planned&catid=41%3Ahighlighted-newsA%20ke&Itemid=105&lang=en
The chief of The Swedish Institute for Infectious Disease Control (SMI), Annika Linde, says in the article: "- The Vaccine is principally natural to the body. The mercury was necessary but the amounts are very small.

 
Quote from:  authorBy Pongphon Sarnsamak The Nation Published on March 11, 2010

An independent academic who monitors social issues yesterday filed a lawsuit in the Central Administration Court against the Government Pharmaceutical Organisation and top health officials for failing to have human trials to test the type-A (H1N1) influenza virus vaccine following reports that six people had died after receiving the vaccine.

'H1N1 Swine Flu Vaccine Insert Admits It Causes Guillain-Barre Syndrome, Vasculitis, Paralysis, Anaphylactic Shock And Death.'http://thebirdflupandemic.com/archives/h1n1-swine-flu-vaccine-insert-admits-it-causes-guillain-barre-syndrome-vasculitis-paralysis-anaphylactic-shock-and-death

The above link may be useful for those who take the vaccination and may like to guard against any adverse effects from it.

$65m of swine flu vaccines may be destroyed in Australia as the vaccine is only effective for 6 months and still the companies make hugh profits
Title: What cancer therapies are available?
Post by: Bored chemist on 02/10/2010 16:50:55
"So every year that you get a flu shot, you are taking a risk that one or more of these substances added by science to make it easier to manufacture will cause a problem in your body."
And it has been shown that the risk is small; less than the risk from catching flu.

"What good is adding mercury in flu vaccine to anyone? "
It acts as a preservative; the fact that thiomersal is more toxic them metallic mercury is a bit of a red herring since it's mercury compounds that are toxic; the free metal isn't very poisonous.

"Here is an example of a vaccine that has been banned in Australia "
Nope; it has been suspended. There's a difference. Also, it has only been suspended for use in young children.

"Now America is spending $2B to engineer plants to produce the vaccine quicker"
Since most Americans are not young children this is perfectly reasonable.

"even though it has been scientifically studied to find it is as effective as a placebo."
A citation would help there.

"So you say, it is NOT OK to take a natural, out of the garden product, as it may have an amino acid that may adversely effect us!"
Nope, nobody said that.
I said that it would make sense to use a purified product rather than the mixture of compounds formed in a plant.
(Incidentally, do you put sugar in your tea, or do you stir it wit a bit of sugar cane until it is sweet enough? The idea is the same)

The other thing I said was that you can take something from a plant and modify it to make it more effective.
(When you get a headache, do you chew on willow bark or take an aspirin?)

"But it is OK to synthesise and add toxic additives and genetically modify the plant so science has control over what we ingest  "
A couple of points. First all things are toxic. Secondly "science" is an abstract concept and therefore cannot control what you ingest. You, on the other hand, can read the labels on things and only eat what you choose to.
If you are eating toxic things that's your choice.

"'H1N1 Swine Flu Vaccine Insert Admits It Causes Guillain-Barre Syndrome, Vasculitis, Paralysis, Anaphylactic Shock And Death.'http://thebirdflupandemic.com/archives/h1n1-swine-flu-vaccine-insert-admits-it-causes-guillain-barre-syndrome-vasculitis-paralysis-anaphylactic-shock-and-death"

Well spotted; all drugs and treatments have side effects. People generally are honest enough to publish them - for example on the page you have cited.
So what?

"$65m of swine flu vaccines may be destroyed in Australia as the vaccine is only effective for 6 months and still the companies make hugh profits"
There are roughly 20 million Australians so that's about 3$ each.
Ask someone with flu if they would have been prepared to pay 3$ to avoid it. I think most would be happy to pay a lot more than that.

Title: What cancer therapies are available?
Post by: echochartruse on 06/10/2010 05:38:13
I had to looked for the side effects and eventually found them but what Dr. is going to read out the list of concerns when administering the vaccination?
Choice,
That's right some don't think they have a choice. Here only 18% of the population took the vaccine and even  though there were a few deaths and other complications, I would imagine that a large proportion of the 18% didn't realize they had a choice or were not given the opportunity to say 'No" and still a profit was made.

We do use natural sugar cane here. although we don't use sugar often, if we use sugar at all. much better than the manufactured sweetener substitute such as the killer sacrin or whatever brand. Where do I buy willow bark please? I chew cloves if I have a tooth ache and I use Radium weed. why hasn't everyone been told of the natural method? why is the natural method called 'alternative' when firstly natural cures should be prime and synthesized should be alternate - in my opinion.
Title: What cancer therapies are available?
Post by: BenV on 06/10/2010 11:18:22
Cloves are definitely good for toothache, but also contain a tumour promoting chemical. BC's point is that a medicalised version would have this chemical removed.
Title: What cancer therapies are available?
Post by: echochartruse on 10/10/2010 00:53:01
Cloves are definitely good for toothache, but also contain a tumour promoting chemical. BC's point is that a medicalised version would have this chemical removed.

Has cloves ever been responsible for tumors?

Quote from:  author http://www.theepicentre.com/Spices/cloves.html
The primary chemical constituents include eugenol, caryophyllene, and tannins. Cloves are said to have a positive effect on stomach ulcers, vomiting, flatulence, and to stimulate the digestive system. It has powerful local antiseptic and mild anesthetic actions. Japanese researchers have discovered that like many spices, clove contains antioxidants. Antioxidants help prevent the cell damage that scientists believe eventually causes cancer. On the other hand, in laboratory tests, the chemical eugenol, has been found to be a weak tumor promoter, making clove one of many healing herbs with both pro- and anti-cancer effects. At this point, scientists aren't sure which way the balance tilts. Until they are, anyone with a history of cancer should not use medicinal amounts of clove. For otherwise healthy non-pregnant, non-nursing adults, powdered clove is considered nontoxic.

"it has been proved not to be carcinogenic"

Quote from:  author http://www.molecular-cancer.com/content/6/1/8
Eugenol is a natural phenolic compound that is the main component of clove oil and it is present in reasonable amounts in several other spices like basil, cinnamon and bay leaves. It is used as antiseptic, analgesic and anti-bacterial agent in traditional medicine in Asia as well as in dentistry as main ingredient of cavity filling cement. Several biological activities of eugenol have been described in literature [8,9] and it has been proved not to be carcinogenic neither mutagenic

so why change it?
Title: What cancer therapies are available?
Post by: echochartruse on 10/10/2010 02:00:36
many things eaten taken in high doses will cause cancer.
such as Fluoride which is added to our drinking water and food so governments can close dental facilities.

Quote from:  author http://www.naturalnews.com/029630_fluoride_teeth.html
Yet the practice has always been controversial, primarily due to fluoride's undisputed status as a highly reactive neurotoxin. More recent studies suggest that ingestion of fluoride can damage the thyroid gland and reduce children's IQ levels. In 2006, a study published in Cancer Causes and Control found that exposure to large amounts of fluoridated water made seven-year-old boys four times more likely to develop a rare bone cancer known as childhood osteosarcoma.

In the new study, conducted on behalf of The Globe and Mail, researchers from Statistics Canada compared the tooth decay rates in the provinces of Ontario, which has Canada's highest fluoridation rate, and Quebec, which has the lowest. Using data on more than 5,000 people, the researchers found no clinically significant difference.

Science seems eager to change, modify and engineer our natural resources without consideration of their long term effect.
As it seems science is run by the corporate $ and not ethics.

So science suggests cloves to be altered genetically because it has a component, not proven to cause cancer but would be more saleable if the component was extracted genetically and made into a pill, then on the other hand fluoride, know to cause bone cancer, is more poisonous than lead and just slightly less poisonous than arsenic, causes chalky teeth etc is added to our water supply.

Epidemiological evidence shows that fluoride causes cancer.
http://www.consumerhealth.org/articles/display.cfm?ID=19990303222823
Title: What cancer therapies are available?
Post by: Bored chemist on 10/10/2010 11:02:12
"what Dr. is going to read out the list of concerns when administering the vaccination?"
One who doesn't want to get struck off for failing to obtain informed consent.

"why is the natural method called 'alternative' "
There are famously two sorts of medicine. That which works; and the alternative.

"such as the killer sacrin "
Has saccharin ever killed anyone?
If not, then you are talking utter bollocks.

" Here only 18% of the population took the vaccine and even  though there were a few deaths and other complications, "
This
http://www.msf.org.uk/measles_epidemic_southern_africa_malawi_20100604.news
is what happens if you don't have a vaccination program.

"still a profit was made."
What's wrong with making a profit?
Since you have access to the web I presume that you have some source of income. Would you have that if nobody was making a profit?


"I would imagine that a large proportion of the 18% didn't realize they had a choice or were not given the opportunity to say 'No""

Once again, you are accusing a vast number of doctors of malpractice. I presume you have no evidence for this slander.

"Where do I buy willow bark please? "
To whom do you plan to feed this toxic material?
Why not use the extracted and derivatised form- aspirin? It's converted back to the active form in the body. It's less damaging to the stomach. It comes in well characterised doses and it's cheap.

"natural cures should be prime"
So, vaccination, which uses the natural immune system is a good thing right? Or are you contradicting yourself?

"Science seems eager to change, modify and engineer our natural resources without consideration of their long term effect."
More slander.
What evidence can you offer for this? After all the reason for the changes is usually well documented (in the way that the change from willow bark to aspirin is explained by the reasons I gave earlier).

"many things eaten taken in high doses will cause cancer.
such as Fluoride which is added to our drinking water and food so governments can close dental facilities."
If you are going to go on about fluoride please start another thread so that cobblers doesn't get mixed up with the other cobblers.
In any event, don't cite pages which say things like "Even at the level they use to fluoridate your public water supply, usually at the rate of about 1 part fluoride for every million parts of water (1 ppm) by weight, it causes severe problems" because that's obvious nonsense.
If it did, we would all be dead.

There's discussion of this gibberish elsewhere, for example here.
http://www.thenakedscientists.com/forum/index.php?topic=25867.0
and it doesn't achieve anything to go over it again.

Incidentally, did it occur to you that people chose governments which fluoridate water in order that they (and their kids) suffer less from tooth decay.

"I chew cloves if I have a tooth ache "
If there was more fluoride in your drinking water, perhaps you wouldn't need the cloves.
Title: What cancer therapies are available?
Post by: echochartruse on 10/10/2010 11:43:10
again...
Quote from:  author http://www.naturalnews.com/029630_fluoride_teeth.html
In the new study, conducted on behalf of The Globe and Mail, researchers from Statistics Canada compared the tooth decay rates in the provinces of Ontario, which has Canada's highest fluoridation rate, and Quebec, which has the lowest. Using data on more than 5,000 people, the researchers found no clinically significant difference.

The Healing Effects of Forests
Quote from:  author http://www.sciencedaily.com/releases/2010/07/100723161221.htm
Forests -- and other natural, green settings -- can reduce stress, improve moods, reduce anger and aggressiveness and increase overall happiness. Forest visits may also strengthen our immune system by increasing the activity and number of natural killer cells that destroy cancer cells.

bottle that!
Title: What cancer therapies are available?
Post by: echochartruse on 10/10/2010 12:03:06

"such as the killer sacrin "
Has saccharin ever killed anyone?
If not, then you are talking utter bollocks.

Quote from:  author http://www.scientificamerican.com/article.cfm?id=artificial-sweetener-linked-weight-gain
The researchers note that the findings gibe with other emerging evidence—including a study published last month in the American Heart Association's journal, Circulation—that shows people who down diet drinks are at a higher risk for obesity  and metabolic syndrome (a medley of medical problems such as abdominal fat, high blood pressure and insulin resistance that puts people at risk for heart disease and diabetes).

please remember doctors are human and make mistakes.

Title: What cancer therapies are available?
Post by: Bored chemist on 10/10/2010 21:43:09
"people who down diet drinks are at a higher risk for obesity"

So what?
People who down diet drinks are quite often on diets.
People on diets tend to be overweight.
people who are overweight tend to suffer from metabolic syndrome.

Anyway. I'm still waiting for the evidence that saccharin ever killed anyone.

Also, if you don't think fluoride is good for teeth then it doesn't make sense to say "Fluoride which is added to our drinking water and food so governments can close dental facilities."
If it didn't work they couldn't close the dentists down.
And you forgot to include this quote from the same page you cited.
"All of Canada's dental associations and its national health agency, Health Canada, officially endorse water fluoridation. In response to the Globe and Mail report, Health Canada immediately sought to cast doubt on the study, pointing out that it failed to assess individual fluoride intake and correlate that with cavity rates."
The best evidence seems to me to suggest that, since many people use fluoride containing toothpaste, the effect of adding it to the water is less significant than it used to be.

Obviously, I can't bottle a trip to the forest.
But if you buy aspirin cheaply rather than wasting time and effort getting willow bark and chewing on it (in order to get a less effective remedy with worse side effects) then you will have more time and money left to go on vacation.
What did you think your point was?

It's not as if a bottle of cloves transports me to the Spice Islands or whatever.
It's an argument in favour of planting trees in parks (which I wholeheartedly support); it's not an argument in favour of eating them.
Title: What cancer therapies are available?
Post by: echochartruse on 11/10/2010 06:53:54
"people who down diet drinks are at a higher risk for obesity"

So what?
People who down diet drinks are quite often on diets.
People on diets tend to be overweight.
people who are overweight tend to suffer from metabolic syndrome.
I think you assume too much.

Quote
Anyway. I'm still waiting for the evidence that saccharin ever killed anyone.
the diseases it causes are life threatening.

Quote
Also, if you don't think fluoride is good for teeth then it doesn't make sense to say "Fluoride which is added to our drinking water and food so governments can close dental facilities."
If it didn't work they couldn't close the dentists down.
And you forgot to include this quote from the same page you cited.
"All of Canada's dental associations and its national health agency, Health Canada, officially endorse water fluoridation. In response to the Globe and Mail report, Health Canada immediately sought to cast doubt on the study, pointing out that it failed to assess individual fluoride intake and correlate that with cavity rates."
The best evidence seems to me to suggest that, since many people use fluoride containing toothpaste, the effect of adding it to the water is less significant than it used to be.
with all doubt being cast on reports, studies and research, without reports,studies or research to back up the doubt. what do you think?
Quote
Obviously, I can't bottle a trip to the forest.
give it time...
Quote
But if you buy aspirin cheaply rather than wasting time and effort getting willow bark and chewing on it (in order to get a less effective remedy with worse side effects) then you will have more time and money left to go on vacation.
I actually don't take aspirin but if there was an option/choice which there is not, I may prefer the natural garden variety and so may many others.
Quote
What did you think your point was?
choice, why do we have to have a processed version if we can grow it naturally ourselves.
Quote

It's not as if a bottle of cloves transports me to the Spice Islands or whatever.
It's an argument in favour of planting trees in parks (which I wholeheartedly support); it's not an argument in favour of eating them.



We find natural cures etc but still we feel the need to synthesise and manufacture/make the components for these cures.
Title: What cancer therapies are available?
Post by: echochartruse on 11/10/2010 07:07:02
 we should have priority finding ways to eliminate cancer causing agents

http://tasmaniantimes.com/index.php/article/cancer-of-the-chudleigh-valley
Title: What cancer therapies are available?
Post by: Variola on 11/10/2010 18:02:05
Quote
We find natural cures etc but still we feel the need to synthesise and manufacture/make the components for these cures.
     

With respect BC has answered this point many times as to why. I am puzzled as to why you cannot seem to accept the explanations as to why, and still seem to be insisting that the natural way is better/more effective/preferable.
Title: What cancer therapies are available?
Post by: Bored chemist on 11/10/2010 19:42:26
"with all doubt being cast on reports, studies and research, without reports,studies or research to back up the doubt. what do you think?"
Like I said.
The best evidence seems to me to suggest that, since many people use fluoride containing toothpaste, the effect of adding it to the water is less significant than it used to be.

I'm still waiting for evidence that saccharin causes disease.

Re http://tasmaniantimes.com/index.php/article/cancer-of-the-chudleigh-valley
Something like one person in 4 gets cancer so the grouping reported is nothing exceptional.
Title: What cancer therapies are available?
Post by: echochartruse on 11/10/2010 23:24:21
"with all doubt being cast on reports, studies and research, without reports,studies or research to back up the doubt. what do you think?"
Like I said.
The best evidence seems to me to suggest that, since many people use fluoride containing toothpaste, the effect of adding it to the water is less significant than it used to be.

I'm still waiting for evidence that saccharin causes disease.

Re http://tasmaniantimes.com/index.php/article/cancer-of-the-chudleigh-valley
Something like one person in 4 gets cancer so the grouping reported is nothing exceptional.


If you read further reports about Tasmanian cancers you will find that there were (not sure of present figure) 3 people from 5 in the entire world with a very rare cancer in an area where there are very high incidence of all other cancers including the Tasmanian Devil's rare and contagious evolving cancer.
that to me is significant.

what i am saying is Saccharin is unnecessary and found to have caused diseases which are fatal. Why 'create' a manufactured synthesised product that is detrimental to our health just because someone or many may think that overweight.......
Quote from: Bored chemist

"people who down diet drinks are at a higher risk for obesity"

So what?
People who down diet drinks are quite often on diets.
People on diets tend to be overweight.
people who are overweight tend to suffer from metabolic syndrome.

and you may feel the way to manage these people's health problem is to at least let them feel they are doing good for their health by 'downing' a synthesised man made version of their worst enemy which has been proven to cause fatal diseases.

In regard to fluoride... you say it is less effective in our water, so why do it? especially if the proven negative effects are worse than the cure.? once the governments agree to introduce fluoride they think they can balance their debt caused by the introduction by closing the dental health care services.
Title: What cancer therapies are available?
Post by: Bored chemist on 12/10/2010 07:23:46
"that to me is significant."
Then learn about statistics.

"and you may feel the way to manage these people's health problem is to at least let them feel they are doing good for their health by 'downing' a synthesised man made version of their worst enemy which has been proven to cause fatal diseases."
Or I may think that they are better off taking drugs that have been tested and found to work and to be cost effective.
Title: What cancer therapies are available?
Post by: echochartruse on 12/10/2010 07:28:06
and some may think it best to find the cancer causing agent and deal with it so we don't need drugs.


http://news.nationalgeographic.com/news/2008/01/080128-devils-cancer.html
flame retardant found in Rare Tasmanian Devils.

here researchers find flame retardant in the Tassie Devils which they suspect is causing their rare cancer.
They assume the flame retardant is being digested when they eat mattresses that may have been dumped.! [???]
The researchers for some reason forget to mention the GM fire retardant mono culture crop of trees which cover a very large area where these cancers are occurring.

and then with the toxic cancer causing chemicals found in the devils, some assume it can't be those chemicals causing their cancer. [???]

Quote
Hamish McCallum, professor of wildlife research at the University of Tasmania, said it's unlikely the chemicals caused the devils' disease.
Title: What cancer therapies are available?
Post by: Variola on 12/10/2010 07:59:47
Quote
and some may think it best to find the cancer causing agent and deal with it so we don't need drugs.
   

Celery parsnips and coffee are all carcinogens, does not mean they cause cancer.


Cancer is a natural occurrence in the body, it is not soly caused by one thing or another. Usually the body deals with cancer just fine, cells repair themselves or apoptose, when they don't cancer can arise.
Cancer can happen even if you live in a bubble with no exposure to any carcinogens whatsoever.
I really do recommend you read up on the biology of cancer.
Title: What cancer therapies are available?
Post by: Bored chemist on 12/10/2010 20:21:25
OK, this is now getting silly.
What in the name of all that's Holy is " the GM fire retardant mono culture crop of trees" mean to mean?
While we are at it, while I support Echochartruse's right to eat what he likes in the same way that I choose to drink more whisk(e)y than is probably good for me, I think we need to remember that this is a scientific website so let's make a few things clear.
His apparent preference for willow bark rather than aspirin seems to be based on the idea that natural =good and artificial=bad.
That's nonsesense.
The most toxic man-made materials are the nerve gases- they typically take a miligrams or so to kill you.
The Natural toxins include things like BTX which is about a thousand times more toxic.
Fundamentally, death is natural so it is absurd to think that natural things must be good for you.

Willow bark works as a painkiller because it contains salicylic acid. The same salicylic acid is produced in the body from aspirin. and it's what gets rid of headaches.
However, the free acid is rather toxic at high concentrations- in particular the phenolic hydroxy group damages the proteins in the stomach. With aspirin, those hydroxy groups are blocked (by sticking an acetyl group on them). That reduces the damage it does in the stomach. The acetyl groups are broken off in the body, but at that stage the free acid has been diluted down and causes less trouble.

So, not only is it an observable fact that aspirin is less toxic than the free salicylic acid found in willow bark, but we even know why this is the case.
On the other hand Echochartruse prefers something which is
more toxic,
less reliable (because the concentration in the bark is rather variable) and
more expensive.
It's his decision- but it's hard to for me to see it as rational.

Incidentally, re the fire retardants in the devils. So what? A while back Americans were not fit for human consumption because their DDT levels were too high. But they lived without any noticeable ill effects.
Also it's probably important to look at what the Nat Geog article which he cited actually says.
"But we're not toxicologists; we need experts to look at the data and get some meaning."
"we found PBDPE in an animal" means that we have very sensitive methods for measuring chemicals; it doesn't mean that the chemical is doing anything.

Also
"It's a really, really strange tumor. All the tumor cells in all the devils are essentially a clone—they are all derived from one individual," McCallum said.

"The event that caused that original mutation to malignancy will never be known," he continued.

"It happened a minimum of ten years ago"

"STOP PRESS"
Death toll from saccharin remains stubbornly at zero!

Title: What cancer therapies are available?
Post by: echochartruse on 13/10/2010 00:11:48
hey you are assuming again.
did I say?..
Quote
His apparent preference for willow bark rather than aspirin seems to be based on the idea that natural =good and artificial=bad.
No I didn't.

What I am saying is if there is a free and naturally available product that is proven to work, then we should be given the info for a choice to use it if we want. we should be told about about all forms of medications without discrimination.
If science feels the need to manufacture/create the component found in the natural form because it is proven to be effective so their pharmaceutical company can control and make a profit from a remedy found in our gardens, then we should be well informed about our choices and the positive effects and negative effects of all natural and synthetic remedies. to make their own informed choice.
 
Aspirin causes internal bleeding, can kill a dog or cat, among other problems, yet it is freely available in the grocery store without mention of this and other bad effects of the drug (larger packaging is required for this, i would imagine). Ibuprofen and some pain killers have now been taken off the grocery shelves, even though the bad effects have been known for decades.

Does science have a conscience? Is science more concerned with getting funding to operate at the hands of multi-corporate rather than finding cures or identifying known cures freely available?
Title: What cancer therapies are available?
Post by: echochartruse on 13/10/2010 02:51:52
Saccharin?

http://www.sciencedaily.com/releases/2008/02/080210183902.htm artificial sweetners cause weight gain
Quote
Authors Susan Swithers, PhD, and Terry Davidson, PhD, surmised that by breaking the connection between a sweet sensation and high-calorie food, the use of saccharin changes the body's ability to regulate intake.

"The data clearly indicate that consuming a food sweetened with no-calorie saccharin can lead to greater body-weight gain and adiposity than would consuming the same food sweetened with a higher-calorie sugar," the authors wrote.

Quote
Monsanto got their start in 1901 selling saccharin to a Coca-Cola addicted public. Questions arose about the safety of saccharin, and the U.S. Department of Agriculture tried to ban it. They failed in their effort against the Monsanto lobby machine.



http://www.sciencedaily.com/releases/1998/04/980422065353.htm
NTP said in one notice it is "especially interested in obtaining additional relevant scientific information in support of or against the petition to delist saccharin" because the three reviews split in their recommendations. Two scientific reviews favored removing saccharin from the Report but an October 30-31 advisory panel -- the NTP Board of Scientific Counselors Subcommittee for the Report on Carcinogens -- recommended by a narrow margin that the sweetener continue to be listed as an "anticipated" carcinogen.

Saccharin has been banned in Canada for decades after scientifically proving it causes bladder cancer. Now science says it causes cancer in rats but that is irrelevant to humans!

http://nutrihealth.in/2008/10/worst-food-additives/

just because it is on the market doesn't mean it is safe - just because it is a natural product doesn't mean it is safe.

for those who care, read this.. all of this. Please listen to the doctors on the video especially.
http://www.bonfirehealth.com/our-doctors/dr-paul/posts/the-diet-soda-death-trap

see also       www.dorway.com
Title: What cancer therapies are available?
Post by: Bored chemist on 13/10/2010 06:57:37
"hey you are assuming again.
did I say?..
Quote
His apparent preference for willow bark rather than aspirin seems to be based on the idea that natural =good and artificial=bad.
No I didn't."

On  the other hand you did say
"Where do I buy willow bark please? "
and
"natural cures should be prime and synthesized should be alternate"

What did you expect people to think you meant apart from that you want to get willow bark, because it's natural and therefore should be, as you put it "prime"?

And, re saccharin,
"Now science says it causes cancer in rats but that is irrelevant to humans!"
exactly, so why are you still going on about it being a "killer"?

Death toll still zero.
Title: What cancer therapies are available?
Post by: echochartruse on 13/10/2010 07:11:34

What did you expect people to think you meant apart from that you want to get willow bark, because it's natural and therefore should be, as you put it "prime"?


you mentioned willow bark not me, i never knew about it til you mentioned it.

yes, natural should be prime. after all isn't that where science gets the components for the synthesised, manufactured, man made version?

In regard to Saccharin, if you watched the video, there is a natural alternative to sugar that has no calories and has other benefits too but we are unable to use it as we do Saccharin due to corporate monopoly.

Please watch the video on the link till the end with an open mind.

Title: What cancer therapies are available?
Post by: echochartruse on 13/10/2010 08:34:46
back to cancer

Duke vaccine extends survival for patients with deadly brain cancers
Published: Monday, October 4, 2010 - 17:03 in Health & Medicine
http://esciencenews.com/articles/2010/10/04/duke.vaccine.extends.survival.patients.with.deadly.brain.cancers

Quote
A new vaccine added to standard therapy appears to offer a survival advantage for patients suffering from glioblastoma (GBM), the most deadly form of brain cancer, according to a study from researchers at Duke University Medical Center and The University of Texas MD Anderson Cancer Center. The vaccine also knocks out a troublesome growth factor that characterizes the most aggressive formof the disease.

 
Quote from:  author http://www.eurekalert.org/pub_releases/1997-06/DU-FRVA-180697.php

The Duke vaccine is also novel in the way it genetically modifies these dendritic cells, researchers said. It uses RNA that "codes" for CEA, found in a number of cancers. This RNA is then duplicated millions of times, and mixed with the dendritic cells......"The advantage of RNA is that it can be used for all immunity types and can be taken from a single cancer cell," he said. "It's better than a DNA vaccine because we have eliminated a step. DNA vaccines need to produce RNA which then prompts the manufacture of proteins."

To date, researchers said no toxicity has been seen in patients during the ongoing phase 1 stage of the trial, which is designed to test safety. Duke is expected to start phase 2 testing of the vaccine's ability to elicit an immune response later this year.
Title: What cancer therapies are available?
Post by: Bored chemist on 13/10/2010 21:27:48
"you mentioned willow bark not me, i never knew about it til you mentioned it."
So what?
You clearly implied that you wanted it.
"yes, natural should be prime. after all isn't that where science gets the components for the synthesised, manufactured, man made version?"

No.
Not any more.
There are some drugs that are based on modified plant toxins, but most new drugs are based on an understanding of the system in the body that they are targeted at.
Wouldn't it have been better for you to ask about that before basing your ideas on a mistake?

What video did you want me to watch?
It's getting late. I had a look at one of the links you posted and it says
"Artificial Sweeteners: A History of Lies and Poison
Don’t have time to read this? Want the bottom line, the take away? Artificial sweeteners are extemely toxic and should be one of the foods you never, ever eat.!"
It's common experience that practically everybody in the Western world eats a variety of artificial sweeteners, yet we are still alive.

It is therefore perfectly obvious that the page you picked is talking obvious nonsense.

Yet you have the front to tell me "Please watch the video on the link till the end with an open mind."

Anyone who believes that sort of thing seems to have a mind so open it will let in any rubbish.

Another of your links tells me
"Caffeine – psychoactive, addictive drug; may cause fertility problems, birth defects, heart disease, depression, nervousness, behavioral changes, insomnia, etc."
Yeah; have you noticed that the people who drink coffee are all screwed up in this way?
I must be in real trouble- I drink diet cola.
But hang on!
Wait a minute; caffeine is natural. Practically nobody actually makes caffeine (except, perhaps, as a lab exercise) because it's easy and cheap to extract it from plants.
Since it's natural, it's another of your favoured "prime" chemicals.
Have you noticed that the links you cite don't actually agree with your professed views?


I am delighted to see that someone has developed another drug to add to the arsenal of anti cancer agents.
It's a little unfortunate that it acts on a cancer that's fairly uncommon.
"GBMs occur in only 2–3 cases per 100,000 people in Europe and North America. " (ex WIKI)
Still I have every hope that it will help those few people, and perhaps, the same idea will be extended to other cancers.

What you seem to have missed here is that, according to your doctrine, they should be opening up the patient's brain and adding a poisonous plant
http://en.wikipedia.org/wiki/Euphorbia_peplus
It is natural and, therefore, according to you should be "prime".
My thought is that we can do better than that. I think the people at Duke would agree with me.



Title: What cancer therapies are available?
Post by: Variola on 13/10/2010 22:37:49


What I am saying is if there is a free and naturally available product that is proven to work, then we should be given the info for a choice to use it if we want. we should be told about about all forms of medications without discrimination.

I agree totally. However what the public does not need is to be told to use natural remedies or the raw compound when it can have negative or unknown side effects. As has been mentioned before on here, several times, the raw or natural base for the medicine is NOT always the best way of taking it.


Quote
If science feels the need to manufacture/create the component found in the natural form because it is proven to be effective so their pharmaceutical company can control and make a profit from a remedy found in our gardens, then we should be well informed about our choices and the positive effects and negative effects of all natural and synthetic remedies. to make their own informed choice.

Why do you persistently ignore the the fact that often compounds are manufactured to eliminate negative effects or risks, Sometimes compound have to be altered or sequences mutated to prevent the drug binding where it shouldn't and altering it's target.
 
Quote
Aspirin causes internal bleeding, can kill a dog or cat, among other problems, yet it is freely available in the grocery store without mention of this and other bad effects of the drug (larger packaging is required for this, i would imagine). Ibuprofen and some pain killers have now been taken off the grocery shelves, even though the bad effects have been known for decades.

And chewing the natural bark version of aspirin can have the same effects. It binds irreversibly to it's COX target. As I recall ( BC may know better) Aspirin is one of the less adulterated drugs there is. 

Quote
Does science have a conscience? Is science more concerned with getting funding to operate at the hands of multi-corporate rather than finding cures or identifying known cures freely available?

Is science a separate entity by itself then? Should pharmaceutical companies research for charitable purposes and not make profit like every other business aims to?

[/quote]
Title: What cancer therapies are available?
Post by: Geezer on 14/10/2010 00:22:29
Is science a separate entity by itself then? Should pharmaceutical companies research for charitable purposes and not make profit like every other business aims to?

Hey! Way cool idea Ms V. JimBob and I are really into transcendental medication.
Title: What cancer therapies are available?
Post by: echochartruse on 14/10/2010 13:51:22
"you mentioned willow bark not me, i never knew about it til you mentioned it."
So what?
You clearly implied that you wanted it.
"yes, natural should be prime. after all isn't that where science gets the components for the synthesised, manufactured, man made version?"

No.
Not any more.
There are some drugs that are based on modified plant toxins, but most new drugs are based on an understanding of the system in the body that they are targeted at.
Wouldn't it have been better for you to ask about that before basing your ideas on a mistake?
exactly my point!
found in natural situation then synthesized, if you had read my posts.


I think you have missed the plot.
As you said here you are tired, haven't read my posts so why bother replying? Maybe you should have a nana nap and then if you feel up to it you can then read the posts, the link, the video and the report here  www.dorway.com, then try to understand it and then comment. Or maybe you are just too set in your ways to see another point of view.
Title: What cancer therapies are available?
Post by: echochartruse on 14/10/2010 14:25:35
Quote from:  author
In 1902, Monsanto's first product was none other than saccharin. Between the years of 1903 and 1905 their entire saccharin production was shipped to a growing soft drink company based in Georgia called Coca-Cola. In 1904 Monsanto introduced caffeine and vanillin to the growing soft drink industry.

By 1915, Monsanto sales hit the one million mark. Approximately two years later Monsanto began producing aspirin. Monsanto was the top aspirin producer in the U.S. until the 1980s.

interesting firstly Saccharin then Aspirin.

I would suggest anyone having Saccharin and for those who care about their health
to see the 80 page scientific report.  www.dorway.com   that some can't face reading athe truth and not just because they are too tired. the scientific report just might open your eyes, change their point of view. Or should I assume you are saying not all scientific reports are correct?

we all know Aspirin causes internal bleeding if taken regularly. yes natural drugs can have adverse effects too but my choice would be to have natural first if possible.

I'm not saying because it is natural it is safe or the best method.
What I am saying is if there is a natural method that works why synthesis it or change it?

willow bark or aspirin it appears to me there are dangers with both. so why dont we have a choice? Unfortunartely most man created drug's effects are not known for decades. then it seems when they are revealed, some are brain washed by either advertising or their old ways or maybe what they have been taught or maybe their thought process is so rigid, no matter what proof you put in front of some, they refuse point blank to even look at it for any consideration, already having their mind made up.



Title: What cancer therapies are available?
Post by: echochartruse on 14/10/2010 14:33:59

Why do you persistently ignore the the fact that often compounds are manufactured to eliminate negative effects or risks, Sometimes compound have to be altered or sequences mutated to prevent the drug binding where it shouldn't and altering it's target.
 

willow bark or aspirin?

i don't know about willow bark, never used it, never had the choice given.
But I do know that there is still negative effects and risks of the manufactured aspirin ( Still NOT eliminated) with brand new health risks.
Title: What cancer therapies are available?
Post by: Bored chemist on 14/10/2010 19:49:45
Hang on. Go back and read what I said.

Modern drug design looks at the molecular level at parts of the body- for example the phosphodiesterase enzyme.
Then it produces chemicals (that are entirely synthetic) which will bind to that molecule - for example, the enzyme and inhibit it.
then they check to see if that compound actually does inhibit the enzyme in a chemical assay.
If it does they test it in animals.
If it's not too toxic and it does its job they test it in humans..


Did you notice that the drug is entirely synthetic and there are no plants involved anymore?

Now don't write trash like ""I think you have missed the plot." when it is clearly you that missed the point.

Don't write "As you said here you are tired,"
when I hadn't said it. (I said it was late- that's not the same thing.
Don't write "As you said ... you ... haven't read my posts so why bother replying?
When, since I rebutted them I clearly had read them.

Don't write "Maybe you should have a nana nap and then if you feel up to it you can then read the posts, " when, as I pointed out, it is clearly nonsense.


Don't expect me to grub about in your multiple posts looking for a video. (Incidentally, did you know you are not meant to double post here?)

As for "Or maybe you are just too set in your ways to see another point of view."
I think the best reply is
Dear Pot,
Thank you for your comment's
signed
Kettle.

You seem not to have realised that I am not set in my ways; I'm quite happy to change them. That's the way science works.
But you need to provide proper evidence of your idea being better than mine.
For example, rather than citing silly websites that say that
"Artificial sweeteners are extemely toxic"
you should actually show some evidence that they have ever caused harm to someone.
Until you do that you are never going to convince me or anyone else.

In much the same way I am not going to be influenced by an hour and a half video from a guy who is trying to sell a book (for a profit- I mention that since you seem to hate profits so much when pharmaceutical companies make them).


I'm also not going to take you seriously when you say anyone interested in saccharin should look here.
http://www.dorway.com/
because it's a website about aspartame.

Are you trying to look foolish?

You publicise your strange beliefs (fair enough, I think free speech is important) and then when I point out that these beliefs are at odds with reality you talk gibberish and cite other sites that do the same.
You refuse to see the obvious truth that if saccharin killed people then most of us would be dead. We aren't so it doesn't.

You refuse to accept answers that are given.
For example "What I am saying is if there is a natural method that works why synthesis it or change it?" has been answered several times. Better selectivity, greater effectiveness lower toxicity better reproducibillity, lower cost (in many cases), fewer side effects, and so on.

You are showing all the signs of being a troll.


You refuse to answer questions asked bout your drivel.
Here's yet another question you won't bother to answer.
when you say "I do know that there is still negative effects and risks of the manufactured aspirin ( Still NOT eliminated) with brand new health risks."

WHAT ARE THE BRAND NEW HEALTH RISKS?


I suggest that if your next post doesn't answer that question clearly and succinctly you should leave the forum, (or be banned if the moderators agree that you are trolling).
Title: What cancer therapies are available?
Post by: echochartruse on 18/10/2010 00:17:33
OK truce?

what is trolling?
 
but if you had read my post with the link I especially asked you to read until the end, you would have seen the video expressing scientific evidence that artificial sweeteners are poison.
Did you read the 80 page scientific report on artificial sweeteners and the problems they cause?
Life threatening diseases!

aspartame = as·par·tame 

NOUN:

  An artificial sweetener, C14H18N2O5, formed from aspartic acid.

www.dorway.com = 80 page scientific report on artificial sweetener aspartame.


But you need to provide proper evidence of your idea being better than mine.
For example, rather than citing silly websites that say that
"Artificial sweeteners are extemely toxic"
you should actually show some evidence that they have ever caused harm to someone.
Until you do that you are never going to convince me or anyone else.

In much the same way I am not going to be influenced by an hour and a half video from a guy who is trying to sell a book (for a profit- I mention that since you seem to hate profits so much when pharmaceutical companies make them).

I'm also not going to take you seriously when you say anyone interested in saccharin should look here.
http://www.dorway.com/
because it's a website about aspartame.

Are you trying to look foolish?

OK, OK I mentioned a brand of artificial sweetener but all artificial sweeteners should be avoided.

The link to the scientists speaking out about artificial sweeteners is in your mind rubbish because one of the scientists or more wrote a book about it. Is that right?

Yes aspartame is an artificial sweetener and that is what the report is about and what I am speaking of here.

What i am trying to say about Asprin is we have substituted an artificial "willow bark" that had adverse effects but is natural for a product manufactured from the components of willow bark (I think from what you say)creating other risks such as internal bleeding, due to it thins the blood.

more health problems arising from Asprin
Constipation; diarrhea; dizziness; drowsiness; headache; indigestion; lightheadedness; nausea; mild stomach pain or upset; vomiting. Severe allergic  reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; blurred vision; fainting; fast heartbeat; fever, chills, or persistent sore throat; loss of coordination; mood or mental changes (eg, agitation, depression, irritability); ringing in the ears; seizures; severe or persistent dizziness, drowsiness, or stomach pain; severe or persistent trouble sleeping; shallow or very slow breathing; tremors; unusual bruising or bleeding; vomit that looks like coffee grounds; wheezing.
to read more see link.
Read more: http://www.drugs.com/sfx/aspirin-side-effects.html#ixzz12eg0QFmt

So i think you are getting me wrong. either I am not writing it incorrectly for you to understand or you don't want to read the proof I submit.

Quote from:  author http://au.askmen.com/sports/foodcourt_200/236_eating_well.html
Saccharin
Products: Hermesetas, Sweet'N Low, Sugar Twin
Sweetness: 300 times sweeter than sugar
Pregnancy: Avoid when pregnant
Fun fact: Saccharin has been banned as a food additive (but not as a tabletop sweetener) from Canada since the '70s.

Discovered in 1879, saccharin is the oldest of sugar substitutes; however, its use only became widespread following the sugar shortage during World War II. While early lab studies showed that saccharin caused cancer in rats, numerous organizations, including the International Agency for Research on Cancer (IARC) and the U.S. National Toxicology Program, have since removed saccharin from their list of suspected cancer-causing chemicals. Their reasoning: The process by which saccharin causes cancer in rats is not applicable to humans. 

http://www.scientificamerican.com/article.cfm?id=artificial-sweetener-linked-weight-gain
BC here is another link you refuse to read or maybe you have read it but disagree.

Calorie-Free Natural Sweetener Moves One Step Closer To Use In U. S.
http://www.sciencedaily.com/releases/2008/09/080922104906.htm

if you want to be healthy and not have sugar why substitute for something that may have more health problems associated?

abcnews.go.com/GMA/Weekend/story?id=3191903&page=1
good for sales not for health.

Quote
It seems to happen particularly with diet versions. A quick search on the Internet reveals a disparate group of mostly young addicts who regularly congregate online to share their battle with their drug of choice: Diet Coke.
http://www.smh.com.au/articles/2002/09/16/1032054760242.html

Stevia is natural and yet it is more profitable to use man made sweeteners.

When you buy your natural medication or synthesised medication you need to find out what other additives are included.
After all natural is not natural if manufactured and processed using non natural products.

http://dorway.com/dorwblog/aspartame-one-mans-poison-another-mans-profit/

http://www.holisticmed.com/aspartame/abuse/

Quote
They’ll call it AminoSweet. The public has learned aspartame is deadly, an excitoneurotoxic, carcinogenic, addictive genetically engineered drug that damages the mitochondria and interacts with drugs and vaccines. It is also an adjuvant, an immune stimulator put in vaccines to activate them. The outcry against this poison is worldwide as educated consumers reject it. Ajinomoto’s deceit is to change names so people will think its a new and safe sweetener

sorry for the extreamely long post I didn't want to multi-post.

Title: What cancer therapies are available?
Post by: Bored chemist on 18/10/2010 07:09:21
So, no answer then.
Since you cannot answer a simple question but seek to distract from it with a double posting that ends "sorry for the extremely long post I didn't want to multi-post." I think you have proved that you are trolling.
http://en.wikipedia.org/wiki/Troll_(Internet)
Bye.
Title: What cancer therapies are available?
Post by: echochartruse on 18/10/2010 08:02:30
http://www.sciencedaily.com/videos/2007/0910-unraveling_brain_tumors.htm
Quote
Brain tumor researchers have found that brain tumors arise from cancer stem cells living within tiny protective areas formed by blood vessels in the brain. Killing those cells is a promising strategy to eliminate tumors and prevents them from re-growing.

Now science has found that cells can change their genetic profile to stop the blood flow to tumors.

Quote
The research shows that cells are able to switch their genetic profile -- turning off genes expressed by blood vessel cells and turning on genes specific to lymphatic cells.
http://www.sciencedaily.com/releases/2010/10/101014083343.htm
Title: What cancer therapies are available?
Post by: Bored chemist on 18/10/2010 19:36:10
Still no answer.
Not very good at this thing called science are you? If you were then you would answer the question.

Incidentally why would I accept a truce from someone who is plainly defeated? (if you want to put it in those terms)
Title: What cancer therapies are available?
Post by: echochartruse on 18/10/2010 22:29:53
BC since you assumed I was trolling, but cleartly I wasn't, just replying to your posts, I refuse to go back there and want to move on. should you persist in not reading my posts but persist in continuing to encourage me to continue on a subject wherby you can bully me and accuse me of things I have no intention to do, I shall not be answering your posts as there is no point if you don't read them or the links I submit to answer your questions.

Title: What cancer therapies are available?
Post by: Bored chemist on 19/10/2010 06:54:20
As I said before,
You are showing all the signs of being a troll.


You refuse to answer questions asked bout your drivel.
Here's yet another question you won't bother to answer.
when you say "I do know that there is still negative effects and risks of the manufactured aspirin ( Still NOT eliminated) with brand new health risks."

WHAT ARE THE BRAND NEW HEALTH RISKS?
Title: What cancer therapies are available?
Post by: echochartruse on 20/10/2010 23:50:31
Ok If I wrote something you didn't understand then I will try to do better here.

what I am saying is,

I never knew I had the option of using willow bark.

You say there are health risks with willow bark, a natural tree and therefore it is better science creates a manufactured version to be able to control the dosage, and whatever.

Manufacturing Aspirin which does the job which it is intended for but creates a "brand new set of risks", one example: internal bleeding.

I don't want to harp on this subject. but I know that my posts are related. I don't start these post subjects.

In regard to cancer, a lot of things are connected to cancer. We seem to be more concerned with what is at the tail end of cancer rather than finding ways to eliminate the causes. Science is encouraged to create new methods, drug components rather than find the cause of the disease and eliminate it. This is not just my view.

My view is that we should all have a truthful, well educated choice on the environment we live in, the remedies we take and the procedures we require throughout our lifetime.
Science should be forefront in defending our natural right to decide and make the right choice.
If willow bark is never offered to me and I don't know about it I am misinformed about the options I have.

too many times some 'product' is created in science but the end product, such as waste, run off, etc are not thought about.

in regard to MG food, Tassie devils, it is all relevant.

you say so what more people are getting cancer
fat people drink diet coke. So what.
maybe not in those words but....

if you look at the other end to see that Saccharin is not a food substance and reminds me of melamine.
Saccharin passes through us unchanged, what goes in comes out. But is known to cause cancer in rats, obesity in people and can be fatal for fetus of mother as it transfers. Saccharin is just one sugar substitute. Sugar substitutes cause known health problems, other substitute sweeteners can be worse for your health, changing chemicals in your body that will eventually poison you. Why substitute. I have posted links to scientific sites for this.

Run off from plantations have been known to cause cancer both natural fields using chemicals and GM fields with rotting produce falling into our streams and in the soil. We should all have a choice in our environment, in our own health and we should look at elimination rather than finding a cure for cancer.


Title: What cancer therapies are available?
Post by: Bored chemist on 21/10/2010 07:11:32
"Manufacturing Aspirin which does the job which it is intended for but creates a "brand new set of risks", one example: internal bleeding. "
Nope, as I explained, the willow bark has that problem too.
I said "Willow bark works as a painkiller because it contains salicylic acid. The same salicylic acid is produced in the body from aspirin. and it's what gets rid of headaches.
However, the free acid is rather toxic at high concentrations- in particular the phenolic hydroxy group damages the proteins in the stomach."



"My view is that we should all have a truthful, well educated choice on the environment we live in, the remedies we take and the procedures we require throughout our lifetime. "
Yet you cite web pages that are about the wrong materials and talk nonsense anyway.

You don't even notice the contradiction when you say
"Saccharin passes through us unchanged, what goes in comes out. But is known to cause cancer in rats, obesity in people and can be fatal for fetus of mother as it transfers. "

Meanwhile you refuse to answer questions and you refuse to listen to answers given to your points.

Why can you not admit you were simply wrong ?
and, before you waste bandwidth with anything else, let's see your answer to this

WHAT ARE THE BRAND NEW HEALTH RISKS?


Title: What cancer therapies are available?
Post by: BenV on 21/10/2010 16:23:10
Bored Chemist is quite right to accuse you of trolling.  You are making blanket statements and then refusing to back them up with evidence, clearly ignoring his questions and comments.  Please answer his question, or at least acknowledge that your comments (in this case, on aspirin) are merely your opinion.  You are usually very good at finding sources to quote, please do so to answer his question.  After which, this thread can return to it's original topic.

Title: What cancer therapies are available?
Post by: echochartruse on 23/10/2010 01:00:32
Bored Chemist is quite right to accuse you of trolling.  You are making blanket statements and then refusing to back them up with evidence, clearly ignoring his questions and comments.  Please answer his question, or at least acknowledge that your comments (in this case, on aspirin) are merely your opinion.  You are usually very good at finding sources to quote, please do so to answer his question.  After which, this thread can return to it's original topic.

I have answered the questions if you care to read the forum. I have included scientific evidence which has been described as "Rubbish" without providing any evidence of why it is deemed to be rubbish.

Yes I may mentioned Saccharin when I meant all artificial sweeteners and I have corrected this in my previous posts.

Saccharin = Cancer in offspring of breast-fed animals, low birth weight, bladder can¬cer, hepatotoxicity
http://www.nursing.upenn.edu/ahnp/Documents/whitehouse_the%20potential%20toxicity%20of%20artificial%20sweeteners.pdf

I've already submitted links to scientific sites that clearly state all sugar alternatives cause health problems.

You only need to look at the material safety data sheet to find the problems caused by Aspirin
if you look at the material safety data sheet for Saccharin you will find the document is mostly stated as "information not provided"

Quote from:  author MSDS_aspririn_BP.aspirin
MATERIAL SAFETY DATA SHEET
(MSDS)
Aspirin
1. Product Identification
Synonyms: 2-Acetoxybenzoic acid CAS No.: 50-78-2 Molecular Weight: 180.16 Chemical Formula: C9H8O4 Urgent contact: Shanghai Sunivo Supply Chain Management Co., Ltd.
Tel: +86 21 3393 3299 Fax: +86 21 5830 7878
URL: www.sunivo.com
Address: Room 502, Building 5, Lane 289 Bisheng Rd., Pudong District, Shanghai, 201204 - P.R. of China
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
Maleic Anhydride 50-78-2 99.5% No
3. Hazards Identification
EMERGENCY OVERVIEW
Toxic if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause dermatitis. May be harmful if absorbed through the skin.

Ingestion: May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion may cause high blood pressure, labored breathing, unsteady gait, lung edema, and coma. Human systemic effects include acute renal failure, acute tubular necrosis, cough, diarrhea, dyspnea (labored breathing), headache, hypermitility, nausea, vomiting, ulceration or bleeding from stomach. Toxic if swallowed.

Inhalation:
Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. May be harmful if inhaled. | MSDS | Page

http://www.sciencedaily.com/releases/1998/04/980422065353.htm
Quote
NTP said in one notice it is "especially interested in obtaining additional relevant scientific information in support of or against the petition to delist saccharin" because the three reviews split in their recommendations. Two scientific reviews favored removing saccharin from the Report but an October 30-31 advisory panel -- the NTP Board of Scientific Counselors Subcommittee for the Report on Carcinogens -- recommended by a narrow margin that the sweetener continue to be listed as an "anticipated" carcinogen.

Shouldn't we have an informed choice on rememdies available?

it is apparent that people here are unaware of the danger of taking Aspirin but fully know the dangers of taking natural remedies. how can anyone make the right decision about their cancer therapy?

http://www.drugs.com/npc/willow-bark.html
I have since found Willow bark.
and now that I know about Willow Bark I am not interested in taking that either. At least that is my decision. It could be different for some others.

BC, You may like to provide evidence why you stated what I say is "Rubbish"

Title: What cancer therapies are available?
Post by: Bored chemist on 23/10/2010 18:38:09
"BC, You may like to provide evidence why you stated what I say is "Rubbish""
Because we are not rats.

At high doses saccharin causes cancer in rats- but through a mechanism that doesn't exist in humans.

In the meantime, rather than lying about having already answered it,
WHAT ARE THE BRAND NEW HEALTH RISKS?
Title: What cancer therapies are available?
Post by: echochartruse on 23/10/2010 21:40:10
BC still not reading my posted links.

Please read the link associating artificial sweeteneers with obesity previously posted.
You are aware that Obese men are at increased risk for erectile dysfunction.
So its proven that artificial sweeteners cause obesity which in turn cause other illnesses and sometimes can be fatal.
Hang on isn't that why people take artificial sweeteners? So they don't get fat?
so now we find the very thing they take the artificial sweetener for to avoid is exactly what the artificial sweetener casues.

does that make sense to you. please read the scientific proof already posted.


Quote from:  authorhttp://www.nursing.upenn.edu/ahnp/Documents/whitehouse_the%20potential%20toxicity%20of%20artificial%20sweeteners.pdf
Susceptible Populatations
Susceptible populations for the potential deleterious effects of artificial sweeteners include diabetics, children, pregnant women, women of childbearing age, breastfeeding mothers, individuals with low seizure thresholds, and individuals at risk for migraines. More studies are required for these susceptible populations. A focus on children is important because they have a higher intake of foods and beverages per kilogram of body weight (Renwick, 2006). Also, more research on the effect of artificial sweeteners on diabetic clients is needed because this population is likely to ingest larger quantities of sugar substitutes.
Because artificial sweeteners are in more than 6,000 products, including foods, medications, and cosmetics, it is impossible to completely eradicate them from daily encounters. Controversy exists over the toxicity of the artificial sweeteners presented in this article. Replication studies and long-term assays are required to decrease fear resulting from the limited research that currently exists.

'Replication studies and long-term assays are required to decrease fear resulting from the limited research that currently exists.'

"Fears resulting from limited research?"

Isn't Saccharin the most tested artificial product in our food on the market? with over 6,000 products including it I would hope so, but apparently Not.

Doesn't the FDA ban substances for human consumption that cause cancer in rats?

Quote from:  author http://leda.law.harvard.edu/leda/data/816/Burnett_07.pdf
This paper will examine the FDA’s role in the four most contentious artificial sweetener
 In 1972, the FDA was faced with two studies suggesting saccharin caused cancer in laboratory animals.5 Rather than issuing an immediate and complete ban under the Delaney Clause, however, then- FDA commissioner Charles Edwards removed saccharin from the list of GRAS substances and issued an interim food additive regulation permitting continued its continued limited use pending further studies of its safety.6 Edwards candidly explained the reasoning behind his actions, admitting “Technically, I could have banned saccharin immediately under the Delaney Clause. in 1972,” but that he had elected not to because “saccharin was, at that time, the only remaining nonnutritive sweetener on the market. American consumers demand the availability of diet food products.
The American public proved to be considerably less alarmed than Commissioner Kennedy at the evidence of saccharin’s carcinogenicity. 

Congress not the FDA had the warning lifted from Saccharin because people wanted it..
Since the benefits of Saccharin is supposedly weight loss or non weight gain and artificial sweeteners has been scientifically proven to cause obesity then shouldn't Saccharin be taken out of our food chain as it is proven that it doesn't do what it has been approved for.
Quote from:  authorhttp://www.amazingpregnancy.com/pregnancy-articles/127.html
Saccharin is another sweetener found in some soft drinks.  It has been found to have teratogenic (causing abnormal fetal development and birth defects) effects in rats. It has also been shown to cause cancer in rats as well.  Human studies have not found these effects.  However, it is probably best to err on the side of caution when it comes to Saccharin.
.................."continued its continued limited use pending further studies of its safety"!

Doesn't the FDA ban substances tested on rats that cause cancer?
Please inform me.

please find the Saccharin MSDS posted separatly due to being so long and it is usless of me to just inclue the link if no one reads it and still wants proof. actually the MSDS basically states that not enough research has been undertaken, in my opinion. please see additional post.
Would you take something that has not been tested correctly for adverse human conditions and the evidence for its safety could not be provided?

here is the link to Saccharin msds
http://www.sciencelab.com/xMSDS-Calcium_saccharin-9923272
for those who want to know
Title: What cancer therapies are available?
Post by: BenV on 23/10/2010 22:15:36
Echo, please don't post anything more about saccharine.  Are you intentionally misunderstanding what Bored Chemist asks of you?

What are the brand new health risks that you claimed are associated with aspirin once it's purified from willow bark?

You made this claim without being aware of the side effects of either.
Title: What cancer therapies are available?
Post by: echochartruse on 23/10/2010 22:38:43
maybe no one understood me.

You assume I was not aware of the side effects of either -WRONG

Please don't assume that I have intentionally misunderstood what bored chemist asked.

BC wanted to know what health risks are associated with the new product that replaces Willow bark.
at least that is my interpretation. New health risks to replace the old health risks. At least that is my impression of his question coming from my statement in that post.

What I am saying is that we have a natural product that does the job. possibly some natural products have side effects and some are not worthy of taking causing adverse reations.

aspirin I was told was invented to substitute Willow bark because of the adverse health risks willow bark contributed too.

willow bark has adverse effects, But so does Aspirin.

Aspirin is a product created to substitute willow bark I am told here.
Yet aspirin creates a whole new lot of adverse effects.

I dont think i have to explain any further. I have listed the problems associated with taking aspirin. We have substituted a natural product with adverse effects for another with adverse effects.

I know the side effects of Aspirin, I had never heard of willow bark before this forum.

If I had the chance of deciding myself which side effects I wanted to take I would hope that science has made it available to me freely.

It appeared that no one knew of the side effects of Aspirin here, which I find amazing that people can take a drug that they are unaware of the problems it causes.

so the manufactured version of willow bark does not exclude health problems.

I would be very interested if anyone will answer my questions.

also please dont write for BC I am sure he can write his own posts, and I dont remember him asking that particular question in those words.
Title: What cancer therapies are available?
Post by: BenV on 23/10/2010 23:50:59
So what are the new health risks? What are the risks of aspirin that are not found in willow bark?  You still claim this to be true, despite admiting that you knew nothing of willow bark mere days ago.

This is your last chance to answer this question that has been repeatedly asked of you.
Title: What cancer therapies are available?
Post by: Bored chemist on 24/10/2010 09:50:06
"Yet aspirin creates a whole new lot of adverse effects.

I dont think i have to explain any further. "
Yes you do.
You need to tell us what those new adverse effects are.
I have been asking you to do this, as clearly as I could, in big letters for some time now and you have refused to answer it.

"and I dont remember him asking that particular question in those words."

These are the exact words, and I like an answer.

WHAT ARE THE BRAND NEW HEALTH RISKS?
Title: What cancer therapies are available?
Post by: echochartruse on 24/10/2010 21:05:01
The first mention of Willow bark was by Bored chemist post 325380 2/10/10. without evidence in support of his statement.

Ben V, I asked you in my post 326286 10/10/10 “Has cloves ever been responsible for tumors?” in response to your statement that cloves contain a tumour promoting chemical that the medicalised version would have removed. Your comment came without supporting evidence and without replying to my question.

My statement was  - why synthesise/create a product when we can use the natural form that is freely available?

Bored chemist’s statement “I said that it would make sense to use a purified product rather than the mixture of compounds formed in a plant... The other thing I said was that you can take something from a plant and modify it to make it more effective.”

OK answered in simple terms.

My next question was if the plant is easily available and works without adverse effect why do we need to synthesise it, such as Radium weed and Cloves.
Not once did I say that natural things are good for you as BC assumed.
When i said “then we should be well informed about our choices and the positive effects and negative effects of all natural and synthetic remedies. to make their own informed choice.”

Natural medication should be ‘prime’ I meant that take away the natural component and some medical therapies may not exist.  Natural components which have been proven to be effective should not need to be synthesised. As this synthesisation creates a whole new set of health risks which I have posted here again....(see my previous post 327823)
“Toxic if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause dermatitis. May be harmful if absorbed through the skin.
Ingestion: May cause irritation of the digestive tract. May cause liver and kidney damage. Ingestion may cause high blood pressure, labored breathing, unsteady gait, lung edema, and coma. Human systemic effects include acute renal failure, acute tubular necrosis, cough, diarrhea, dyspnea (labored breathing), headache, hypermitility, nausea, vomiting, ulceration or bleeding from stomach.
Toxic if swallowed.
Inhalation:
Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. May be harmful  if inhaled.”

Bored Chemist's quote
Quote
Modern drug design looks at the molecular level at parts of the body- for example the phosphodiesterase enzyme.
Then it produces chemicals (that are entirely synthetic) which will bind to that molecule - for example, the enzyme and inhibit it.
then they check to see if that compound actually does inhibit the enzyme in a chemical assay.
If it does they test it in animals.
If it's not too toxic and it does its job they test it in humans..

Are you saying if it kills aminals then it can be tested on humans? such as Saccharin?

In regard to Aspirin/willow bark.

you are asking me to compare the 2 even though I was not the person who firstly stated Willow bark.

Well I have and it appears to me that all the synthesisation to create the purified product and the modification of the substance to make it more effective has not been proven but Aspirin's toxicity is apparently higher or the same as Willow bark.

unless you can prove different and since BC introduced Willow bark into this forum I think it's his duty to back up his statement not me.

I ask again... If the natural product is no different in effectiveness, toxicity etc, Why do it?
is it just another  'political dogma'?
Title: What cancer therapies are available?
Post by: Variola on 24/10/2010 21:48:26
Quote
I ask again... If the natural product is no different in effectiveness, toxicity etc, Why do it?
is it just another  'political dogma'?

And you have been told why, repeatedly by both BC and myself.

Why do you keep ignoring the answers? Why keep asking the same question over and over to get mileage out of your anti-pharma stance.

This is why you have been accused of trolling Echo.
Title: What cancer therapies are available?
Post by: rosy on 24/10/2010 22:38:08
OK, Echo, please read this summary of the willow bark/aspirin question. It is merely a summary of information other people have posted elsewhere in this thread.

Dried, powdered willow bark has been used for thousands of years to treat pain and fever. Dried, ground-up willow bark was reasonably effective, but since the amount of the active ingredient (in this case salicylic acid) in any plant is very variable, depending on the growing conditions, time of year, etc., it was impossible to know exactly what dose was being administered on any given occasion. (This is a problem with "herbal" medicines generally.)

In the 19th century it became possible to isolate salicylic acid, and accurate doses could be given, but the side effects, notably a tendency to cause gastric bleeding, were a major problem.

It was discovered that salicylic acid could be chemically modified to form acetylsalicylic acid, and that this had similar pain and fever suppressing properties but a markedly improved side effect profile. This acetylsalicylic acid is commonly known as aspirin. Aspirin still has some side effects, most drugs do. We can chose to take them or not (that's what the information leaflet in the packaging is for).

Title: What cancer therapies are available?
Post by: rosy on 24/10/2010 22:51:03
Quote
If the natural product is no different in effectiveness, toxicity etc, Why do it?

That's one hell of an "if".

Using the ground-up, crude plant material is foolhardy, because one doesn't know from one batch to the next what the concentration of the different ingredients may be. That being so, an overdose, or an insufficient dose, becomes not so much a risk as a likelihood.

Isolating a pure chemical compound from a natural source is certainly sometimes a useful way of obtaining a drug (penicillin, from mould, is a case in point). But once we know the chemical structure of a particular drug molecule, it makes not a shred of difference whether we isolate it from a plant (or whatever) or whether we synthesise it in the lab. So we do whatever is the most efficient (it may not be possibly to harvest sufficient of the plant of interest for example).

Beyond that, modifications to the molecular structure are all aimed at making the drug better, either by improving its efficacy, or reducing its side effects. The advantage of aspirin over salicylic acid is that it has fewer side effects. Many drugs used against bacteria or parasites (for example penicillins antibiotics or artemisinins for malaria are used initially in their natural form, but as the target infectious agents develop resistance chemically modified versions are often used because whereas the original drug is no longer effective, the modified version is.

So no. Not a political dogma. I hope that answers your question.
Title: What cancer therapies are available?
Post by: Bored chemist on 25/10/2010 07:06:02
"Are you saying if it kills aminals then it can be tested on humans? such as Saccharin?
"
Yes, of course I am.
All drugs are toxic because all things are toxic.
It's a good idea to have a rough estimate of that toxicity , measured in animals, before giving it to humans.

I don't think I have to say much about willow bark; I only introduced it as an example of an outdated natural remedy. Rosy has described it and its history quite enough.
Now, please answer the question
WHAT ARE THE BRAND NEW HEALTH RISKS?
Title: What cancer therapies are available?
Post by: JimBob on 27/10/2010 03:39:41
Ben, etc.. I would like to point somehting out to Echo.

Echo -

There are no new health risks. In fact, aspirin is safer than willow bark.

"In 1897 Felix Hoffmann created a synthetically altered version of salicin (in his case derived from the Spiraea plant), which caused less digestive upset than pure salicylic acid. The new drug, formally Acetylsalicylic acid, was named Aspirin by Hoffmann's employer Bayer AG. This gave rise to the hugely important class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs)."

Having taken aspirin for a very long time - it is the best drug for my arthritis, I can guarantee that the above statement is absolutely true.

If you wish to argue a point, the least you can do is get the facts correct.

Oh, and the digitalis I take for my heart's arrhythmia is MUCH safer than foxglove - from which the drug came - because the manufactured drug, which is exactly the same chemical as in foxglove - can be given in exact quantities, not the random amount that one gets with a tea made from the dried foxglove. Being random, it can cause death if the dosage is off by only a relatively small amount.

The whole thesis of your argument is scientifically indefensible.

You are polluting this forum which I might remind you is based on science, not hearsay and web myths.
Title: What cancer therapies are available?
Post by: SteveFish on 29/10/2010 01:08:10
In my experience there are three kinds of trolls.

1) Ideological trolls have a specific political or business viewpoint that they wish to advance. They drop their line in forums to disturb discussions that oppose their views. They do this by clever questions or responses that rile up the forum and essentially stop any useful discussion. In some instances these folks are paid for this activity.

2) Hobby trolls are the original version of trolling behavior. They just enjoy making others get angry and argue, and get enjoyment from this activity. They often have their own sites where they show off and brag about their accomplishments. They succeed in their hobby, and get the most enjoyment, from the maximum disruption they cause on a forum.

3) Dunning-Kruger trolls (wiki Dunning-Kruger effect if you don't know about the publication). These folks also have a hobby that involves a set of beliefs based on no evidence whatsoever. They are incapable of understanding evidence and the normal logic of argument so that what they say, especially in a science forum, is so outrageous that honest members just can't resist trying to explain. People interested in science are susceptible because they are often born teachers. This is our own Echochartruse.

The best way to deal with these people is to not respond at all, but my experience with myself and others is that this is almost impossible. So my compromise is to write very little. This type of troll is so caught up in their own belief that they often write volumes that we all just have to read if we want to help them. Read just enough to get the gist and only respond with one short point, such as Bored chemist's "what are the new health risks?" Don't say much of anything else and let the troll write his/her silly essays. They eventually realize that they are no longer having any fun. This is the only way to win a troll game.

Steve
Title: What cancer therapies are available?
Post by: Bored chemist on 29/10/2010 06:58:09
I think you may well be right Steve.
The effect (detailed here)
http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
is certainly consistent with Echo's behaviour.
I wonder if pointing this out will help him to realise this.
Title: What cancer therapies are available?
Post by: Hugh888 on 02/12/2010 06:43:58
# Detoxification, the removal of toxins from the body, is considered by  many clinics as a very important part of their treatment.  A variety of approaches are used, including colon cleansing, fasting, chelation, water therapy, heat therapy, and nutritional, herbal, and homeopathic methods. Max Gerson introduced coffee into the enema procedure, which causes the liver to release stored up toxins into the digestive system to be eliminated. Increasing your water intake may be one of the best ways to get rid of toxins in the body.
# Nutritional therapy: Two types or approaches are emerging. One is a specialized combination of nutrients used as a targeted cancer therapy, depending on the individual needs of the patient. The other, which also depends on the needs of the patient, is a more general approach seeking to boost health and strength.
# Psychology and Psychotherapy, although used at most clinics, would be considered an adjunctive therapy. Psychological counseling, support groups and even psychotherapy make up a critically important aspect of therapy in the world's most successful cancer treatment centers. Some doctors have reported that a traumatic psychological event in a person's life may trigger the appearance of cancer one to two years later. Music, meditation, relaxation techniques, and stress reduction have proven to significantly enhance the power of the immune system. Some therapists include emotional and even spiritual counseling, not only for the person's regular life, but in dealing with the trauma of cancer
Title: What cancer therapies are available?
Post by: SteveFish on 02/12/2010 15:47:54
Hugh888:

Your post is an embarrassing collection of assertions made by charlatans who steal money from the gullible and helplessly ill. With the exception than many real clinics employ counseling to help patients psychologically deal with their illnesses, not to cure an illness (if it isn't psychological in origin), there isn't a single medically correct statement in your post. All you have to do to prove me wrong is provide some credible research to support your points. This is a science site, so don't offer opinions or articles in websites that don't reference their claims for evidence, just provide us with some science. A forlorn hope.

Steve
Title: What cancer therapies are available?
Post by: Variola on 02/12/2010 20:05:38
Steve,

Hugh888 is a spammer, I already flagged him up on another thread  [:)]
Title: What cancer therapies are available?
Post by: SteveFish on 02/12/2010 20:18:03
Thank you Variola. I thought he might just be a common troll. Steve
Title: What cancer therapies are available?
Post by: BalletGirl on 03/01/2011 14:28:42
Hi guys,
I'm new here so please dont start arguments with me if I get something wrong  [:-[]

I think that spending time with family and close friends helps to take your mind off whats going on around you. Most of the time you just need a distraction, because when you are focusing on something else, your brain cant be in two places at once, so the pain subsides for a while.

Anyway, thats just my opinion :)
Title: What cancer therapies are available?
Post by: Bored chemist on 10/01/2011 06:56:38
"if any of you knew anything about health you would know that a healthy human has a ph above 7 and one with cancer has a  acidic ph around 3 or 4 and the way to cure cancer is with an alkalizing lifestyle where only alkalizing food is consumed and only distilled water is drank"

LOL
Normal blood pH is slightly alkaline and will stay that way pretty much whatever fad diet you eat.

[Sorry to have to modify your post BC but the poster you have quoted has now been banned for contravening forum policy - Regards, Mod]
Title: Re: What cancer therapies are available?
Post by: cancer_war on 23/01/2013 14:32:29
Hi,

For certain cure of cancer, cardio, aids etc. i wrote a petition to the US White House.
I need 100000 signature. Please sign it.

We demand $1 trillion/year fund to challenge against cardiovascular disease,cancer and death.
We want the creation of funds,at least $1 trillion/year, against all the diseases, primarily cardiovascular, cancer, diabet, genetic, AIDS, organ failures, that plague mankind.

We want funds for development of certain treatments, biological development of human organs, anti-aging and ultimately aim to stop death for biological reasons.

In addition to US budget, a special tax can be taken for immortality. Also by ensuring participation of the G20 countries, perhaps ensuring other countries this fund can be created.

The results of the researches and investigations must be available to public, In other words, it must be provided that everyone can reach the results.

It should be noted that, the biggest enemy is nature itself. Lets stop it immediately in order to stop the death of people.



http://wh.gov/yD9P
Title: Re: What cancer therapies are available?
Post by: profound on 25/01/2013 20:14:51
Science has grown so much and is growing is there any medicine found for cancer?

Spam link removed - Mod

only treatment is chemotherapy.


and more chemotherapy.

it will always be the treatment for cancer.

always.just like the last 50 years.

makes a ton of money.
Title: Re: What cancer therapies are available?
Post by: CliffordK on 26/01/2013 02:34:06
only treatment is chemotherapy.

and more chemotherapy.

it will always be the treatment for cancer.

always.just like the last 50 years.

makes a ton of money.
There are in fact multiple treatments.
Surgery
Radiation Therapy
Chemotherapy.

Often used in conjunction with each other.  Cancer is a systemic disease, and thus best treated with systemic medications.  I.E.  if you cut it out, but miss a few cells that have already migrated from the primary site, the patient is at MUCH greater risk.  So, one generally uses chemotherapy in to augment other treatments.

New treatments on the horizon are viruses targeted to the tumor cells, or injection of immunogenic antigens directly into the tumor cells.  Cancer cells are rapidly growing, and an alternative to surgery is intra-arterial plugging of the arteries feeding the tumors.

Title: Re: What cancer therapies are available?
Post by: profound on 26/01/2013 13:09:18
only treatment is chemotherapy.

and more chemotherapy.

it will always be the treatment for cancer.

always.just like the last 50 years.

makes a ton of money.
There are in fact multiple treatments.
Surgery
Radiation Therapy
Chemotherapy.

Often used in conjunction with each other.  Cancer is a systemic disease, and thus best treated with systemic medications.  I.E.  if you cut it out, but miss a few cells that have already migrated from the primary site, the patient is at MUCH greater risk.  So, one generally uses chemotherapy in to augment other treatments.

New treatments on the horizon are viruses targeted to the tumor cells, or injection of immunogenic antigens directly into the tumor cells.  Cancer cells are rapidly growing, and an alternative to surgery is intra-arterial plugging of the arteries feeding the tumors.




There are in fact multiple treatments.
Surgery
Radiation Therapy
Chemotherapy.

Yes,you are totally right.

Yes these have been around for decades and will continue for decades.Also known as cut/burn/slash.

The advantages from a profit point of view is that any company can make a drug,hire a couple of "reviewers" showing marginal improvement,discard,hide,suppress negative results,milk a few billion out of the drug and then move on to the next one.

Of course these drugs don't work or have horrific side effects and you end up 6 feet under as wormfood but who cares?

They laugh all the way to the bank.

A study of cancer drug research studies found 80% were fraudulent,plagiarized,unrepeatable,had missing data,fudged,messaged,or written by people on the company's payroll or ghost written showing positive effects by "respected" people who had been given $10000 to $100000 to let their name be put on the research.
Title: Re: What cancer therapies are available?
Post by: RD on 26/01/2013 14:42:27
A study of cancer drug research studies found 80% were fraudulent ...

Can you post a link to that study ?
Title: Re: What cancer therapies are available?
Post by: profound on 27/01/2013 16:27:41
A study of cancer drug research studies found 80% were fraudulent ...

Can you post a link to that study ?



http://www.guardian.co.uk/science/2012/sep/13/scientific-research-fraud-bad-practice

This is very good article and shows just bad the situation is and why you should never just believe any study no matter where it comes from.The links are in the article.

And it a shocking indictment of "research" and scientists.Read the whole article.


links are in the article.

"Worse, in medicine, it can delay the development of life-saving treatments or prolong the use of therapies that are ineffective or dangerous. Malpractice comes to light rarely, perhaps because scientific fraud is often easy to perpetrate but hard to uncover..."

more than two-thirds of the biomedical and life sciences papers that have been retracted from the scientific record are due to misconduct by researchers, rather than error...

Those who document misconduct in scientific research talk of a spectrum of bad practices. At the sharp end are plagiarism, fabrication and falsification of research. At the other end are questionable practices such as adding an author's name to a paper when they have not contributed to the work, sloppiness in methods or not disclosing conflicts of interest..


In medicine where the profit motive over rides all ethical considerations the fraud is even more prevalant.Billions rest on the marketing dangerous and ineffective drugs.

Glaxowellcome has been fined not millions but billions over the last 30 years for all sorts of practices.
This is on record.Just google them.You will be shocked.
Title: Re: What cancer therapies are available?
Post by: schneebfloob on 27/01/2013 16:53:19
I absolutely despise posts with an agenda, and over the past couple of days I have seen quite a number of them. Post after post of 'beware of the evil big pharma'.

I'm talking about stuff like this:
Quote
The advantages from a profit point of view is that any company can make a drug,hire a couple of "reviewers" showing marginal improvement,discard,hide,suppress negative results,milk a few billion out of the drug and then move on to the next one.

No names named, no proof, pure conjecture. If you know something then you should be taking it to the authorities. I cannot stand this drivel. If you have something to add about cancer research then by all means go ahead. But this is not a forum for discussing conspiracies. Keep them to yourself.
Title: Re: What cancer therapies are available?
Post by: peppercorn on 27/01/2013 19:16:26

http://www.guardian.co.uk/science/2012/sep/13/scientific-research-fraud-bad-practice

This is very good article and shows just [how] bad the situation is and why you should never just believe any study no matter where it comes from.
The links are in the article.

Still no mention of a link therein to support your claim that a "study of cancer drug research studies found 80% were fraudulent".
The article, though not painting an exactly rosy picture of some scientists, would seem orders of magnitude off the rash generalisations you are making, and certainly does not support the argument that medical drugs are, in effect, worse than useless; though it would be nice to see more altruistic organisations getting the research investment occasionally.
Title: Re: What cancer therapies are available?
Post by: RD on 27/01/2013 19:18:48
A study of cancer drug research studies found 80% were fraudulent ...

Can you post a link to that study ?

http://www.guardian.co.uk/science/2012/sep/13/scientific-research-fraud-bad-practice


I couldn't find "80%" in that article ...

 [ Invalid Attachment ]
 
There's dishonesty in all walks of life, but you've yet to provide evidence that it's as high as "80%" in cancer drug research.

If modern cancer therapies were ineffective why do people with cancer survive longer now than in the past ? ...

(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.cancerresearchuk.org%2Fprod_consump%2Fgroups%2Fcr_common%2F%40nre%2F%40sta%2Fdocuments%2Fimage%2Fcrukmig_1000img-12647.jpg&hash=b3ba62a720b084f4d775ad74d83af01d)
http://www.cancerresearchuk.org/cancer-info/cancerstats/survival/latestrates/survival-statistics-for-the-most-common-cancers
Title: Re: What cancer therapies are available?
Post by: profound on 29/01/2013 16:17:11
A study of cancer drug research studies found 80% were fraudulent ...

Can you post a link to that study ?

http://www.guardian.co.uk/science/2012/sep/13/scientific-research-fraud-bad-practice


I couldn't find "80%" in that article ...

 [ Invalid Attachment ]
 
There's dishonesty in all walks of life, but you've yet to provide evidence that it's as high as "80%" in cancer drug research.

If modern cancer therapies were ineffective why do people with cancer survive longer now than in the past ? ...

(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.cancerresearchuk.org%2Fprod_consump%2Fgroups%2Fcr_common%2F%40nre%2F%40sta%2Fdocuments%2Fimage%2Fcrukmig_1000img-12647.jpg&hash=b3ba62a720b084f4d775ad74d83af01d)
http://www.cancerresearchuk.org/cancer-info/cancerstats/survival/latestrates/survival-statistics-for-the-most-common-cancers

The article has links in it in a pale blue.Maybe you are using a old black and white monitor and can't see.

The article clearly states more than 2/3 are fraudulent,etc.

2/3 =66%

80% is clearly more than 66% and the article states "at least".

Since big bucks is involved you almost certainly can guarantee the figure is higher because money makes people lie,cheat,steal and kill.Do you agree?
I mean that is what the NEWS is ALL about.Lying,cheating stealing and killing.Do you agree.

Do you watch the News?  And it is mostly about lying,killing,cheating,stealing.


There was anther paper with the an at least 80% figure implying it was more than 80%.

I can't find that at present but I will post when I do.

Now regarding your graph.It is very dodgy and very misleading.I wonder who put it together and what their agenda was.Where did you get it from?

Each year, more than 1 million cancer patients receive outpatient chemotherapy, radiation, or both. On the US National Library of Medicine website (PubMed), - is the news of a study estimating the overall contribution of chemotherapy to 5-year "survival" in adults in the US at a shameful 2.1%. Top this off with 201 side effects listed on the Chemocare website alone. The American Chinese Medicine Association says that "most cancer patients die of chemotherapy." How does this factor into the medical dictum "First Do No Harm"? It is actually misleading to promote chemotherapy for cancer treatment because it permanently damages the body and immune system and causes other cancers to spring


Here is proper graph with actual FIGURES of SURVIVORS  not MISLEADING percentages.

i mean 10000 got treated and 100 are alive or 10 are alive after 5  years.Look at those figures and how different from that misleading graph you posted.

Also a friend of my brother-in law just died of cancer today.He had been treated with chemotherapy "therapy" for the last 2 months.He was only 26.Leaves a wife and child behind.

http://www.oasisadvancedwellness.com/learning/chemotherapy-effectiveness.html



http://articles.mercola.com/ImageServer/public/2008/August/8.5chemo_survival.jpg
Title: Re: What cancer therapies are available?
Post by: CliffordK on 29/01/2013 20:05:23
One of the things that cancer patients desperately need is HOPE, and offering no treatment is very hard on the patients.

Treatments can be single modality (one of surgery, radiation, or chemotherapy), or a combination therapy, often determined by the cancer presentation.  Surgery can also be targeted as curative or palliative. 

Looking at the Morgan et al meta-study (http://fiocco59.altervista.org/ALLEGATI/MORGAN.PDF) (study cited on the previous page by profound), the "Percentage 5-year survivors due to chemotherapy" is not representative as the percentage of survivors that had received chemotherapy, but is calculated based on the fraction of the patients in which the therapy was applicable.
(incidence) x (subgroup with operable cancer or applicable benefit) x (benefit from chemotherapy).  So, if only half of the cases are applicable, the numbers being reported are about half of the actual benefit.

So:
Cancer TypeInclusions/Exclusions5 year survival Benefit from Chemo
Head and Neck Cancer,(63% Australia, 47% USA Stage III & IV)4%
Esophageal Cancer,67% non metastatic8%
Stomach Cancer40% operable, 31% margin negative11%
Colon CancerDuke's C, 35% Australia, 21% USA5%
Rectal CancerDuke's B&C, 60% Australia, 38% USA9%
Pancreatic Cancer?5.6% "Objective Response"
Insufficient Data for overall survival benefit
Small Cell Lung Cancer19% incidence3.5%
Non Small Cell Lung Cancer81% incidence, 21% operable5% benefit
Soft Tissue Sarcoma No overall survival benefit
Malignant Melanoma No overall survival benefit
Breast Cancer (node negative)85% operable, 64% node negative3% to 3.9%
Breast Cancer (node positive)85% operable, 36% node positive2% to 6.8%
Uterine CancerNo overall survival benefit
Cervical Cancer 12%
Ovarian CancerFIGO II-IV 79%11%
Prostate Cancer No overall survival benefit
Testicular Cancer, Seminoma 95% Benefit from Chemo,
20% Relapse
Testicular Cancer, Non-seminomatous 95%
Bladder Cancer 5% (not significant?)
Kidney Cancer No overall survival benefit
Brain CancerGrade II-IV, 62% - 82% 6% (1 year)
Hodgkin's Lymphoma Stage I-IIA, 15% Benefit
Stage IIB-IV, 80%
Non Hodgkin's Lymphoma, Large B 50%
Unknown Primary Site No overall survival benefit

I suppose the question is what one considers to be a "benefit" of chemotherapy.  5%, 10% additional survival beyond what is gained by surgery, or other treatments?

Chemo therapy isn't appropriate for all groups, but it does seem to have a benefit for select groups of patients, as noted above.

Here is a study of survival curves for esophageal cancer, studying surgery alone vs surgery + chemotherapy (http://jco.ascopubs.org/content/21/24/4592.full.pdf).  A relatively small study, but representative.

When you look at the overall survival curves.  Early, there is no benefit from the chemo therapy, but after about 3 years, there is a moderate improvement in the chemo group of with an additional 9% 5 year survival rate. 

 [ Invalid Attachment ]

This second chart is "Disease Free Survival" (not overall survival as in the first graph).  They've separated it by lymph node involvement at the time of surgery.

 [ Invalid Attachment ]

The curves are much closer for the groups with no node involvement.

Those with node involvement shows much greater separation between the curves with about a 14% difference in the 5 year disease free survival rate.

So, the question is...  is a few percent survival improvement worth it?  Perhaps 10%? 
It certainly is worth it for those members of the 10%.  And, unfortunately, one doesn't really know if one is in the surviving half or not, or whether the chemo would be of benefit to the particular patient.

Obviously each type of cancer is different.  If I was a patient with fully encapsulated cancer with a clean resection and no lymph node involvement, I might consider not having chemotherapy until one noted recurrence or lymph node involvement.

On the other hand, in cases with more developed cancer and/or lymph node involvement, chemotherapy would seem to have enough benefit that one might choose the therapy.
Title: Re: What cancer therapies are available?
Post by: profound on 05/02/2013 17:41:19


So, the question is...  is a few percent survival improvement worth it?  Perhaps 10%? 
It certainly is worth it for those members of the 10%.  And, unfortunately, one doesn't really know if one is in the surviving half or not, or whether the chemo would be of benefit to the particular patient.

Obviously each type of cancer is different.  If I was a patient with fully encapsulated cancer with a clean resection and no lymph node involvement, I might consider not having chemotherapy until one noted recurrence or lymph node involvement.

On the other hand, in cases with more developed cancer and/or lymph node involvement, chemotherapy would seem to have enough benefit that one might choose the therapy.

2 or 10 % it is pretty pathetic after many decades of research.In the U.K a "charity" called Cancer Research U.K. has pulled in £4000 million or £4 Billion since 2001.£400 million a year.You must have seen the non-stop ads.Where did the money go?

They have not pioneered a single new treatment or saved a single life according to their own website.

Also you have failed to mention that many people "diagnosed" with cancer don't actually have it.

The false positives rate is very high and can vary from at least 10% to 30%.

With an increasing amount of private scanning being promoted/advertised and poorly trained staff with a automatic incentive to diagnose any little abnormality as cancer this is just going to get worse.

After all if it is cancer and you get it wrong your ass will get sued so the incentive is automatically if in doubt say it is cancer and get chemo.

Many benign growths come and go and need not be necessarily cancerous.

This might explain the Chemo "success" stories.The patient never had cancer in the first place and got chemo but survived in spite of it's very toxic nature and might explain your 10% success rate.

In fact this has not to my knowledge been taken account in chemo "success" stories,the patient never had cancer and so the chemo "remission" is considered a "success".

Was it not the Lancet that once said more people die from the Chemo than from the cancer?
Title: Re: What cancer therapies are available?
Post by: CliffordK on 05/02/2013 19:03:05
Any good scientific study will have at least 2 randomized groups, one that receives the treatment, and one that doesn't (or receives the "standard care") called the control group.  Often medications in the control group are given as "Placebos", or a pill with no active ingredients, so that the patients, and even those administering the meds get the same treatment as the experimental group, without the active ingredient.

By comparing the experimental group to the control group, one can ignore those that undergo spontaneous recovery, or perhaps didn't have the disease after all.

False positive diagnoses are a problem.  However, something like Breast cancer usually goes through multiple tests.  Initial lump detected.  Confirmed with mammogram and/or ultrasound.  Initial Biopsy.  Surgery + histology of excised material + surrounding lymph nodes.

Here is a chart of 5 Year Breast Cancer Survival. (http://www.cancerresearchuk.org/cancer-info/cancerstats/types/breast/survival/breast-cancer-survival-statistics)
Figure 3.3: Breast cancer (C50), Age-Standardised Five-Year Relative Survival Rates,
Females, England and Wales 1971-1995, England 1996-2009
(https://www.thenakedscientists.com/forum/proxy.php?request=http%3A%2F%2Fwww.cancerresearchuk.org%2Fprod_consump%2Fgroups%2Fcr_common%2F%40nre%2F%40sta%2Fdocuments%2Fimage%2Fsurv_5yr_breast_png.png&hash=7db4fb5033791ef6864c0b9e3e6a4ef7)

In the last 30 to 40 years, the 5 year survival rate has increased from about 50% to over 80%, or about 1% a year.

There can be an early detection bias in such studies (not always a bad thing). 

While not all of the improvement would be due to chemotherapy, the oncologists seem to be doing something right.
Title: Re: What cancer therapies are available?
Post by: profound on 11/02/2013 18:19:36
"Yet aspirin creates a whole new lot of adverse effects.

I dont think i have to explain any further. "
Yes you do.
You need to tell us what those new adverse effects are.
I have been asking you to do this, as clearly as I could, in big letters for some time now and you have refused to answer it.

"and I dont remember him asking that particular question in those words."

These are the exact words, and I like an answer.

WHAT ARE THE BRAND NEW HEALTH RISKS?



Corporations are not people; they do not care about you, nor should you truly care about them.

The only thing corporations are concerned about are their bottom line; if doing something helps them profit, they'll do it. If doing something HURTS their bottom line (such as, oh, I don't know, paying taxes), they'll avoid doing it as best as they can.

Any example you might provide to prove otherwise is only an example of image control, a calculated effort to improve their standing in the eyes of their consumers.

Bottom line: report what corporations do. If it's bad, it'll help your fellow consumers avoid being screwed over. If it's good, it'll steer them towards companies that care enough about their image to not be total d***bags.
Title: Re: What cancer therapies are available?
Post by: profound on 13/02/2013 07:28:01

http://www.guardian.co.uk/science/2012/sep/13/scientific-research-fraud-bad-practice

This is very good article and shows just [how] bad the situation is and why you should never just believe any study no matter where it comes from.
The links are in the article.

Still no mention of a link therein to support your claim that a "study of cancer drug research studies found 80% were fraudulent".
The article, though not painting an exactly rosy picture of some scientists, would seem orders of magnitude off the rash generalisations you are making, and certainly does not support the argument that medical drugs are, in effect, worse than useless; though it would be nice to see more altruistic organisations getting the research investment occasionally.

A shocking 88 percent of 53 "landmark" studies on cancer that have been published in reputable journals over the years cannot be reproduced, according to the review, which means that their conclusions are patently false.

C. Glenn Begley, a former head of global cancer research at drug giant Amgen and author of the review, was unable to replicate the findings of 47 of the 53 studies he examined. It appears as though researchers are simply fabricating findings that will garner attention and headlines rather than publishing what they actually discover, which helps them to maintain a steady stream of grant funding but deceives the public.

"These are the studies the pharmaceutical industry relies on to identify new targets for drug development," said Begley about the false studies. "But if you're going to place a $1 million or $2 million or $5 million bet on an observation, you need to be sure it's true. As we tried to reproduce these papers we became convinced you can't take anything at face value."

Begley says he cannot publish the names of the studies whose findings are false. But since it is now apparent that the vast majority of them are invalid, it only follows that the vast majority of modern approaches to cancer treatment are also invalid.

Back in 2009, researchers from the University of Michigan's Comprehensive Cancer Center also published an analysis that revealed many popular cancer studies to be false. As can be expected, one of the primary causes of false results was determined to be conflicts of interest that tended to favor "findings" that worked out best for drug companies rather than for the people


Publication bias is profoundly serious, because the end result is that people frequently will die if they are making choices on inaccurate information and recommendations. Research does not exist in a vacuum. Published studies are used by doctors and health agencies as the basis for making recommendations and writing prescriptions. When they’re given a radically skewed picture of the facts, how can they make sound recommendations?

According to Goldacre, negative results missing in action cuts to the core of publication bias. When negative results are suppressed, people die. Sometimes in very large numbers.

In 1980, a study was done on a heart arrhythmia drug called lorcainaide. It included 100 people. Half of them received the drug; the other a placebo. Among those who received the drug, 10 died, compared to just one death in the placebo group. The trial was stopped and the drug was abandoned. The results of the study were never published. Over the next decade, other pharmaceutical companies created and marketed similar drugs to treat arrhythmia in heart attack patients. An estimated 100,000 people died before the deaths were finally traced back to the drugs. This case is now used as a perfect example of the price of publication bias, as the publication of those negative results could have provided an early warning.

Currently, the science behind the flu drug Tamiflu is also M.I.A., which should concern every citizen in every country that recommends it and stockpiles it in anticipation of a flu pandemic. Remarkably, eight of the 10 studies on Tamiflu have never been released for review, despite years of effort.
Title: Re: What cancer therapies are available?
Post by: evan_au on 13/02/2013 11:23:58
A new kind of therapy is being investigated now, based on DNA sequencing of the cancer - this relies on very cheap DNA sequencing (which is not there yet, but is getting much better every year).

Usually there are several key mutations that were required to make the original cell cancerous, often involving gene regulation, growth regulators, blood-vessel growth factors, apoptosis inhibition, immune system suppression, etc.

DNA sequencing is still too expensive to do large trials of this technique. And because the technique only analyses one person's cancer, it is not a "one size fits all" solution, but requires expert interpretation for each patient. However, more of the necessary logic should be able to be incorporated into diagnostic tools, over time.

One factor that makes cancer so difficult to treat is that DNA auditing is often turned off within the cell, and DNA copying errors are very frequent. This makes it likely that a subsequent mutation will bypass the treatment, and the cancer will resume its parasitic growth.
Title: Re: What cancer therapies are available?
Post by: profound on 20/02/2013 20:49:22
that's right.you just keep on believing that.
Title: Re: What cancer therapies are available?
Post by: profound on 20/02/2013 22:36:35
A new kind of therapy is being investigated now, based on DNA sequencing of the cancer - this relies on very cheap DNA sequencing (which is not there yet, but is getting much better every year).

Usually there are several key mutations that were required to make the original cell cancerous, often involving gene regulation, growth regulators, blood-vessel growth factors, apoptosis inhibition, immune system suppression, etc.
  • By looking at these key mutations, it is sometimes possible to identify a small molecule which blocks one of these key mutations, or one of the upstream/downstream steps from this mutation, and in this way to block the uncontrolled cancer growth.
  • It is also possible to prioritise which of the conventional cancer therapies might be more effective against this particular cancer

DNA sequencing is still too expensive to do large trials of this technique. And because the technique only analyses one person's cancer, it is not a "one size fits all" solution, but requires expert interpretation for each patient. However, more of the necessary logic should be able to be incorporated into diagnostic tools, over time.

One factor that makes cancer so difficult to treat is that DNA auditing is often turned off within the cell, and DNA copying errors are very frequent. This makes it likely that a subsequent mutation will bypass the treatment, and the cancer will resume its parasitic growth.


that's right.you just keep on believing that.

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