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Life Sciences => Physiology & Medicine => Topic started by: michel_mr on 06/01/2005 18:37:21

Title: about blood groups incompatibilities
Post by: michel_mr on 06/01/2005 18:37:21
hello every one,i want to ask  your help,i know the story of rhesus and how o rhesus negative woman should be treated with antiD after 7 months of pregnancy with a rhesus positive baby....but i dont understand why we cannot think the same way about ABO system,i mean if rhesus antibodies can pass through placenta and provoke a big damage to the RBC of the fetus ,why anti A or anti B will not behave the same as anti Rh and pass through the placenta ...thanks for your help.example:a woman group B and her fetus group A ,why the anti A of the mother won't agglutinate with the antigen A of the fetus.


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hello all
Title: Re: about blood groups incompatibilities
Post by: Ylide on 08/01/2005 19:56:41
I don't know the mechanism of blocking ABO antigens from crossing the placental barrier, but this mechanism occasionally does fail resulting in chimeric blood types for the offspring and is thought to influence manifestation of autoimmune disorders in children and in the mothers as well.  



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Title: Re: about blood groups incompatibilities
Post by: DrN on 08/01/2005 23:18:33
maybe we should all blood test our partners for compatibility before marriage and procreation.

both my parents are A+, and luckily both me and my husband are A+ too. phew!

do people generally find people of the same bloodgroups attractive? is it like the pheromone thing?
Title: Re: about blood groups incompatibilities
Post by: qazibasit on 24/01/2005 20:08:05
well its a good question to be answered and is to simple ABO group antibodies are IgM type and they cant cross the placental barrier whereas Rh antibodies are IgG type and can cross the placental barrier.