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Victor,NCC sometimes gives you negative values, not because calculation is not reliable , but because serum copper is not adjusted for age or sex and ceruloplasmin correctly. If you dont trust these calculations which I do the correct way , you can always do direct free copper test.
There are formulas that calculate free levels using albumin multiple also , same as for calcium. You can test free estradiol and compare it with your free copper levels, which will correlate/You cant find this stuff on the internet.)))
I dont look at studies , I am far past that crap, only my own tests from now on.Since 90% of all the studies are bogus , And I can always find you 2 or 3 contradicting studies .
Values that I present completely match hairtests with 100% accuracy , if you know how to read the hairtest correctlyMost of the time I ask for both blood and hair .
Victor, I think this one is better explaning copper adjustment if you still interested in calculations...http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860450/If not do the free copper, the problem is that it is rarely could be obtained in Russia, as you probably know.
Victor, I guess it is your way to make me do your research for you..))) You know how busy I am .....
Victor, Your wikepidia article states on ranges..Since you read this article I dont understand your questions. The answers are right there.Usual or optimalReference ranges are usually given as what are the usual (or normal) values found in the population, more specifically the prediction interval that 95% of the population fall into. This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in the population as well. More specifically, optimal levels are generally close to a central tendency of the values found in the population. However, usual and optimal levels may differ substantially, most notably among vitamins and blood lipids, so these tables give limits on both standard and optimal (or target) ranges.
Gonda, Why do you think you have werner syndrom.. Premature aging could be from many imbalances. Collagen loss, wrinkly skin and so forth .. These are symptoms of copper deficiency.. Same as POIS, copper could be deficient or toxic in POIS, in both cases you would get low ceruloplasmin and high histamines.
Well, now it all makes sense. Gaurav person is a front man of some kind of setup. ID registered a month ago, never posted pre Kumars statements. Indian conspiracy?
Also a huge possibility would be POT SMOKING. I bet Nathan smokes a lot of POT.