Naked Science Forum

On the Lighter Side => Complementary Medicine => Topic started by: liz on 28/12/2003 00:27:14

Title: Alzheimer's disease and sage
Post by: liz on 28/12/2003 00:27:14
I understand that there has been quite a lot of research into the positive effects of sage in relation to Alzheimer's Disease.

Does anyone have any information about the properties of sage, or any other natural substances (eg gingko biloba) that can (apparently) influence brain function, and slow down the development of dementia.

[?] Liz
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 28/12/2003 09:16:26
Well, it's my understanding that folks who use their brains in an analytic manner (puzzles, problem solving, science, etc) are less likely to develop Alzheimers.  Perhaps it's feasible that herbs which stimulate the brain can have a beneficial effect in this way.  



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Title: Re: Alzheimer's disease and sage
Post by: bezoar on 28/12/2003 15:41:48
So then, if we all keep participating in this forum, then none of us will end up with Alzheimer's, right?

Bezoar
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 28/12/2003 17:47:49
I can think of a few that don't put a lot of mental power into their posts.  *cough* christianchick *cough*

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Title: Re: Alzheimer's disease and sage
Post by: Donnah on 29/12/2003 02:37:50
Autopsies on Alzheimers victims showed that they had as much as four times the concentration of aluminum in the brain, particularly the hippocampus (memory area).  They also had elevated mercury levels.  Apple pectin is a natural chelate that is good for removing heavy metals from the body.  Better yet, learn what contains aluminum and avoid it.

Sources of aluminum include aluminum cans for soda, iced tea etc., aluminum cookware, deodorant (aluminum chlorhydrate), processed cheese, antacids and antidiarrheal remedies in the form of aluminum salts (aluminum hydroxide, kaolin, attapulgite, aluminum magnesium silicate).  Read labels.
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 29/12/2003 09:16:20
I've heard vague information about aluminum being related to Alzheimer's, but was never quite sure exactly how...thanks Donnah.  Are the metals the suspect cause or just a byproduct of another chemical defect in the body's chemistry that is causing accumulation of metals in the brain due to an enzyme or something shuttling them around?



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Title: Re: Alzheimer's disease and sage
Post by: Donnah on 29/12/2003 23:19:58
Great question Jay.  Chronic calcium deficiency can change the way the body uses minerals (causing aluminum accumulation) so logic would dictate that other body chemicals could do the same.  At this point in time metals are on the list of suspects.
Title: Re: Alzheimer's disease and sage
Post by: tweener on 05/01/2004 20:34:35
I've only heard vague information about aluminum and alzheimer's, but it is enough that I've eliminated all aluminum cookware from my kitchen.  I'm trying to eliminate the teflon, but my dad would probably set the house on fire trying to cook on stainless.

Maybe I'll have to use this as an excuse to eliminate deodorant. [:D]


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 06/01/2004 02:29:18
What's so bad about teflon?  It's pretty inert.



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Title: Re: Alzheimer's disease and sage
Post by: tweener on 06/01/2004 22:07:53
I've heard vague information that teflon is highly carcinogenic (sp?).  And in my house, it gets burned pretty regularly, and then it starts flaking off into the food.


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 07/01/2004 06:04:03
Teflon is a fluorinated carbon (polymerized C2F4) compound and is neither electrophilic in nature nor is it prone to radical formation aside from those that are normally able to homolytically break carbon double bonds.  Those are the big 2 for carcinogenic character.  I don't think there's anything in the digestive tract capable of homolysis of carbon double bonds, otherwise almost everything you eat would form lots of free radicals.  

Overheating Teflon can cause vaporization to some degree, but that's unlikely to happen at normal cooking temperatures...I believe it's somewhere around 260 C before this happens.  The flaking off is just a byproduct of heat and scraping.  You're in more danger from the butter or oil emitting carbon monoxide when the burner's used on high.

The production of Teflon is another story though....the stuff they make it out of and the byproducts of the manufacturing process are quite nasty and are unfortunately turning up in wildlife, air, and water.



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Title: Re: Alzheimer's disease and sage
Post by: chris on 08/01/2004 19:15:56
quote:
Originally posted by cannabinoid
 I don't think there's anything in the digestive tract capable of homolysis of carbon double bonds, otherwise almost everything you eat would form lots of free radicals.  



But what about bacteria present in the digestive tract. I suspect that they may well have some additional metabolic pathways that could allow this to occur. In addition, free-radicals clearly do crop up in the G.I. tract because people develop bowel cancer.

Chris

"I never forget a face, but in your case I'll make an exception"
 - Groucho Marx
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 08/01/2004 19:50:22
But would free radicals made from the occasional Teflon particle be any worse on your system than a free radical made from, say, a chain of an unsaturated lipid?  DNA is damaged regardless, right?

BTW, how is it that eletrophilic molecules and free radicals are able to get into cells and seek the DNA anyway?  I mean, there are 2 phosoplipid layers, one for the cell membrane and one for the nuclear membrane, and a ton of water, ions, and organelles in the way...how is it they home in on the DNA so readily?



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Title: Re: Alzheimer's disease and sage
Post by: tweener on 09/01/2004 04:42:52
Like I said it was only vague information.  

Asbestos is also very stable and can cause cancer, though I think the whole thing is way overblown.


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 09/01/2004 07:10:02
Asbestos doesn't cause cancer from a chemical reaction, though.  It creates microtears in lung tissue that repeatedly scar over and retear.  I'm not sure exactly how this causes cancer, though, but the phenomenon is due to the small, sharp crystalline structure of the asbestos minerals.  I'm pretty sure Teflon doesn't break off as jagged sharp particles.  

Coincedentally, I used to work in a lab that scanned air samples for asbestos.  That was one of the worst jobs I ever had....looking at slide after slide after slide of air filter cross sections, all day, 8 hours a day, 5 days a week.



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Title: Re: Alzheimer's disease and sage
Post by: chris on 09/01/2004 17:30:41
Free radical species which damage DNA are readily synthesised within the cell itself as a bi-product of metabolism. Oxygen is the commonest causative culprit, so as obligate aerobes we find ourselves in a catch 22 situation.

Chris

"I never forget a face, but in your case I'll make an exception"
 - Groucho Marx
Title: Re: Alzheimer's disease and sage
Post by: tweener on 09/01/2004 18:46:21
Funny, I never thought of myself as an "obligate aerobe", but I guess it's true!


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John
Title: Re: Alzheimer's disease and sage
Post by: bezoar on 11/01/2004 03:59:19
I read that the biggest source of mercury in our bodies comes from coal burning energy plants.  And as for the aluminum, lay off the Mylanta too

Bezoar
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 11/01/2004 09:18:20
From an evolutionary standpoint, why did we evolve a metabolism mechansim that can damage our DNA?  Modern metabolisms all originate with glucolysis, which is supposedly VERY ancient.  It's just the very end of the proton transport chain (where oxygen uptakes a proton to form water) where oxygen is needed.  

Is it the reaction of oxygen with OTHER things in the cell that causes the problem or is it a "misfiring" of the proton gradient that causes an incomplete reaction of protons and oxygen leading to free radicals?  Inquiring minds want to know!

as far as mercury goes, I know that long-lived fish are also sources of mercury poisoning...they accumulate high levels of mercury from the ocean in their muscle tissue, which we then eat.  If you're pregant especially, do NOT eat things like swordfish.



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Title: Re: Alzheimer's disease and sage
Post by: bezoar on 12/01/2004 03:41:51
I think Tuna, too, is high in mercury, but apparently the coal burning plants contribute more damage than eating fish.

Bezoar
Title: Re: Alzheimer's disease and sage
Post by: tweener on 13/01/2004 17:21:56
I just read an article that farm-raised Salmon is very high in contaiminants and the "authorities" are recommending that people don't eat it more than once a month.  I don't know the sources, but it bothers me that our food supply is becoming contaminated in so many ways.


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John
Title: Re: Alzheimer's disease and sage
Post by: bezoar on 14/01/2004 14:06:13
I read something about that too -- that the farm raised fish are high in contaminants.  You'd think when they're farm raised, they'd be purer, huh?

Bezoar
Title: Re: Alzheimer's disease and sage
Post by: Donnah on 15/01/2004 02:59:18
Apparently the farm raised salmon get a lot of salmon lice too.
Title: Re: Alzheimer's disease and sage
Post by: tweener on 15/01/2004 03:14:48
The farm raised Salmon are "farmed" in the ocean, but confined to cages and fed commercial feed.  (National Geographic had an article a few months ago is how I know anything about this.)  So, since costal waters are usually more contaminated than deep ocean, it makes sense.  Maybe.  Maybe this "study" was bogus too.


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John
Title: Re: Alzheimer's disease and sage
Post by: tweener on 15/01/2004 03:22:37
quote:
Originally posted by cannabinoid

From an evolutionary standpoint, why did we evolve a metabolism mechansim that can damage our DNA?  Modern metabolisms all originate with glucolysis, which is supposedly VERY ancient.  It's just the very end of the proton transport chain (where oxygen uptakes a proton to form water) where oxygen is needed.  

Is it the reaction of oxygen with OTHER things in the cell that causes the problem or is it a "misfiring" of the proton gradient that causes an incomplete reaction of protons and oxygen leading to free radicals?  Inquiring minds want to know!

...



I would think from an evolutionary standpoint this would not matter much.  When aerobic metabolism was evolving, the life span of the individauls was very short, thus the cancers caused by free radicals would have little or no impact on the survival of the genes.  Even now that it is firmly established, the only species that have a problem are the ones that live an unnaturally long life span (like humans and maybe their pets), and even then they have usually finished their reproductive years before cancer sets in.


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 15/01/2004 08:08:31
But there are other long-lived animals though, many of which have been around for millions of years.  I've never heard of whale or turtle cancer.  Of course, whales and turtles don't smoke or inhale asbestos.



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Title: Re: Alzheimer's disease and sage
Post by: luckywood on 14/02/2004 14:51:30
There are many alzheimers that have been cured through 'THE TOLE'S WAY OF MEDICATIONS'
 Please look into google and search

Thanks

Title: Re: Alzheimer's disease and sage
Post by: tweener on 15/02/2004 04:29:56
quote:
Originally posted by cannabinoid

But there are other long-lived animals though, many of which have been around for millions of years.  I've never heard of whale or turtle cancer.  Of course, whales and turtles don't smoke or inhale asbestos.



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Animals do get cancer but I was curious and did some searching.  Whales of several species are developing cancers.  I'm not sure if the rate is increasing or the increased study is finding more cancers.  Animals of any species have evolved to maintain their lifespan.  Humans are the only animals that have artificially (non-evolutionary) increased their lifespan.  So, it's my hypothesis that the cancer rate (and other diseases) is increasing because our lives are longer than our bodies are designed to support.  Just a side effect of the increased lifespan.


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 21/02/2004 02:45:59
That makes perfect sense, John.  Your body deals with cancerous cells every day. DNA is constantly destroyed or mutated by various environmental factors (sun UV, background radiation, free radicals from foods and oxygen, pollutants) but you have mechanisms for dealing with the mutated cells.  There's always the small chance your body won't catch the mutation for one reason or another.  The longer you live, the more contaminants you expose yourself to, the greater the risk.  



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Title: Re: Alzheimer's disease and sage
Post by: bezoar on 21/02/2004 16:01:22
And the longer you live, the weaker your immune system gets, and I don't base that on any studies I've read but just on personal experience.  Seems the elderly don't have the resistance that younger people have and they also take longer to recover, and don't respond as well to antibiotics.
Title: Re: Alzheimer's disease and sage
Post by: tweener on 22/02/2004 02:02:47
Getting old is hell.


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John
Title: Re: Alzheimer's disease and sage
Post by: Ylide on 22/02/2004 04:40:32
That's why I changed careers.  I sure wasn't going to find the secret to immortality by keeping stupid teenagers out of corporate networks.





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Title: Re: Alzheimer's disease and sage
Post by: bezoar on 22/02/2004 18:37:50
Getting old is hell, but as they say, consider the alternative.  Actually, I'm lucky.  I feel good, just look older.  Honestly, I'm happy to still be here, so it's not hell for me.  Cannabinoid, what career did you change to?
Title: Re: Alzheimer's disease and sage
Post by: tweener on 23/02/2004 04:07:45
I don't really feel old either, but I don't feel as young as when I was younger.


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John
Title: Re: Alzheimer's disease and sage
Post by: bezoar on 24/02/2004 01:51:28
To the extent that I feel a lot smarter, I don't feel as young.  But I am enjoying my life a hell of a lot more now than I did when I was younger -- and I laugh a lot more now too, even at myself.
Title: Re: Alzheimer's disease and sage
Post by: tweener on 24/02/2004 19:22:40
Physically, I feel a lot younger now than I did two years ago.  Mentally, I'm realizing what "over the hill" really means.  I know (hope) that I have many good years left before things really start falling apart, but I know it's coming.  I'm just trying to slow it down a little.


----
John
Title: Re: Alzheimer's disease and sage
Post by: Donnah on 25/02/2004 02:05:03
That's the advantage of having been sick and in pain so much of my younger life.  In the words of James Brown "Oh, I feel good, just like I knew that I could!"

Yesterday I saw a doctor who hasn't seen me since I was at my worst.  It took a moment for her to recognize me, and I got a real kick out of her shocked expression.
Title: Re: Alzheimer's disease and sage
Post by: sphygmo on 23/08/2004 05:15:47
But what about Iris Murdoch? Does this mean she didn't use her brain in an analytical manner? [:)]

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