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Oh, another thing that I wanted to mention. Those people taking Glucophage (Metformin) for Diabetes. Metformin can heavily contribute to Adrenal insufficiency and severely exacerbate PIOS.
I think that there could be 2 steps (or more) in POIS. And the first step is dopamine adrenaline conversion with orgasm, excessive for us. This adrenaline cause symptoms described by Imre1 and are corrected by beta blockers.
Hey, I believe I have been suffering from POIS for about 5 or 6 years. I am only 20 years old. I at first thought that my symptoms were caused from religious guilt. But whenever I have an orgasm from masturbation I feel miserable for EXACTLY 3 days. It is like a clock. As soon as I release I feel an intense warm feeling in my body. That night I am unable to sleep. I sweat alot even though I am not hot. The following day I feel mildly depressed and nervous and confused. My mind feels so different than before my release. The second day is the worse and I try not to even talk to anyone. It is so depressing. I just don't feel like myself. The third day I begin to feel better. After exactly 72 hours I feel fine. This happens everytime. BUt I suffer no physical pain. It's all mental. I am worried because I am so young. I want to marry but I want to feel normal after I have sex. At first I thought that these symptoms would disappear after I got married due to religious reasons. Now, after reading this forum I have doubts. I currently go for about a month without an orgasm because I can't stand the after effects. But I have such a stong sex drive I can't permantely avoid orgasm. I take no medicine and I am in perfect physical condition. I just want to enjoy pleasure but act normal. I don't know what to do.. anyone want to help?I have spent the last year or two experimenting with various mental opinions while masturbating to no avail. I am sure I must be suffering from POIS and I am so glad I am not alone.
demografx - I was under the impression that it was important to post things on this Forum that would help people get back to a normal life ASAP. Theophylline, as I mentioned is essentially, sustained release caffiene, so for me to suggest, "You may want to try, Theophylline" is quite reasonable. As for Glucophage, I have had diabetics tell me that they have had CFS and have it completely vanish upon discontinuing this medication. After discussing it with the head endocrinologist in our department we concluded that it was most likely due to it deminishing the responsiveness of the Adrenal gland to stimulation. If you are uncomfortable with me posting, keep in mind, I have 20 years of medical experience, 13 years in the hospital environment. I have prescribing authority on my unit and am fully licensed to give medical advice.
...I can't stand the three or so days after a release. It is like living on a high plateau of feeling good and normal and then falling off the edge when I release......So I want to believe that the symptoms are associated with the orgasm and not the ejaculation. I have since tried to ejaculate without an orgasm unsuccesfully.
Theophylline, as I mentioned is essentially, sustained release caffiene [sic], so for me to suggest, "You may want to try, Theophylline" is quite reasonable.
Quote from: imre1 on 28/09/2008 13:38:47Now for the realy unconventional question. (Many are not going to like this, but the question should be asked at least once anyway).What would be the result of suppressed homosexuality on dopamine and prolactin production?One would think that if you have sex with people you are not sexualy attracted to dopamine would be low and as a result prolactin would be high.I'm not sure what the result on the neurochemicals would be. If you're having sex with someone you're not attracted to, the experience would probably be lessened in most aspects (e.g. less dopamine and prolactin?).
Now for the realy unconventional question. (Many are not going to like this, but the question should be asked at least once anyway).What would be the result of suppressed homosexuality on dopamine and prolactin production?One would think that if you have sex with people you are not sexualy attracted to dopamine would be low and as a result prolactin would be high.
I found this on wikipedia.org - interesting: if oxytocin and prolactin are responsible for the refractory period maybe these chemicals are related to our symptoms....