Naked Science Forum
Life Sciences => Physiology & Medicine => Topic started by: Meera Makwana on 02/03/2009 09:30:02
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MeeraM asked the Naked Scientists:
hi there, I would like to know how chronic liver disease can lead to cirrhosis of the liver?
I know that it is related to the pace at which our immune response acts, that is by having a rapid break down of Hepatitis B means that you develop liver failure, but having a slow break down mean you develop inflammation of the liver - cirrhosis.
Many thanks
Meera M
What do you think?
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rapid breakdown by the virus means that ur liver cells are killed, they lyse and dump all their contents = liver failure.
chronically it is ur immune sytem killing away the infected cells and these as any other injury leave behind a scar- fibrosis of the liver which is cirrhosis... when ur own body attacks itself to fix something the cell contents are mostly not releases into the surroundings. it's either done by apoptosis or by phagocytosis....
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Because of chronic damage to the liver, scar tissue slowly replaces normal functioning liver tissue, progressively diminishing blood flow through the liver. As the normal liver tissue is lost, nutrients, hormones, drugs and poisons are not processed effectively by the liver. In addition, protein production and other substances produced by the liver are inhibited.
http://www.umm.edu/liver/chronic.htm
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Listen to the answer to this question on our podcast. (http://www.thenakedscientists.com/HTML/podcasts/show/2009.12.06/)
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Liver is a important organ of human body, but people frequently come across different types of liver problems. Good diet can help in the proper functioning of your liver. Spam removed