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Author Topic: TCA cycles and energy sources  (Read 3712 times)

Offline Ylide

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TCA cycles and energy sources
« on: 01/11/2004 11:52:05 »
Studying the TCA cycle got me thinking about something...

Any intermediate in the TCA cycle can be taken into the cycle and used to generate ATP, GTP, electrons for electron transport, and all that good stuff we need to live.  Why can't we just eat, say, a crapload of citric acid and live off of that?  Glycolysis is inefficient anyway, it's just way to break the goo we normally eat down into nice bits of pyruvate for the REAL energy production, right?  What would be be the ramifications of bypassing it entirely and just eating TCA intermediates?



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Offline Fearsome Anna

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Re: TCA cycles and energy sources
« Reply #1 on: 02/11/2004 04:44:52 »
Because unfortunately, citric acid doesn't give us any of the other nutrients we need to keep functioning. We're not much good with rickets! Glycolysis is horrifically inefficient though. No wonder we go into food comas. We're too busy splitting carbon chains to pay attention at work.

Besides, citric acid doesn't taste so hot. [xx(]

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Offline Ylide

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Re: TCA cycles and energy sources
« Reply #2 on: 02/11/2004 11:34:27 »
Ah right.  Guess we kinda need proteins and vitamins to keep us alive, eh?  It sounded like a great idea at 4 in the morning.  =)

Welcome to the forums, btw.

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« Last Edit: 02/11/2004 11:34:49 by Ylide »
 

Offline dongilbert

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Re: TCA cycles and energy sources
« Reply #3 on: 02/12/2004 21:26:02 »
re inefficient glycolysis

theoretical studies indicate that glycolysis is more efficient when oscillating and maximally so when doing so at the resonant frqeuency.

If anyone is interested I have proposed a theory of ageing based on this  

Gilbert, DA. (1995). Ageing, oscillations and efficiency. BioSystems. 36: 1-5
 

Offline Ylide

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Re: TCA cycles and energy sources
« Reply #4 on: 12/12/2004 05:06:42 »
Do you have a link to a non-pay site where this can be found?  PubMed only links to something that costs $30 USD

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Offline Ylide

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Re: TCA cycles and energy sources
« Reply #5 on: 13/12/2004 08:41:24 »
Glycolysis may be inefficient in and of itself, but it's what gets the TCA cycle and eventually electron transport processes going from glucose molecules.  Otherwise, you'd be stuck with fatty acids and proteins as your only source of ATP, and those aren't as quickly process nor as easily stored as glucose.  



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Re: TCA cycles and energy sources
« Reply #5 on: 13/12/2004 08:41:24 »

 

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