The Naked Scientists

The Naked Scientists Forum

Author Topic: Genetics Journal Article  (Read 2238 times)

Offline ellemkay

  • First timers
  • *
  • Posts: 2
    • View Profile
Genetics Journal Article
« on: 29/10/2008 15:33:05 »
Hello all,

I have to do a presentation based on a recent journal article, and I was wondering if any of you had read any interesting journal articles in the last 6 months that have to do with genetics. I haven't found a great one yet and welcome any suggestions. Thanks!


 

Offline Pseudogene

  • Jr. Member
  • **
  • Posts: 27
    • View Profile
Genetics Journal Article
« Reply #1 on: 29/10/2008 18:49:17 »
A bit more specific? I read interesting journal articles on genetics everyday, they only focus on autoimmune diseases like systemic lupus erythrematosus and rheumatoid arthritis.

Depends on where you're looking as well, and whether you want to something disease related (the most prevalent journal type), population based, evolutionary, etc.

The current fashion in genetics of complex disease is focusing on using genome-wide association studies of single nucleotide polymorphisms to identify novel disease risk alleles.  They utilise SNP chips that cover the whole genome (not uniformly though) with tag SNPs.  These allow quick genotyping of large cohorts of patients and controls for various diseases, which can then be used to determine correlations with diseases and disease subsets.  Pretty exciting really.

One recent, a bit more than six months ago, was the Framingham Heart Study, an ongoing study into the genetics of coronary artery disease and other cardiac disorders like atherosclerosis.  If you're using PubMed then just type in Framingham Heart study and GWAS (genome-wide association study), and you'll be guaranteed a plethora of articles.

If you're looking for a more functional approach with less emphasis on statistical analysis of large patient cohorts then try searching through the "American Journal of Human Genetics" and "Human Molecular Genetics" from Oxford Journals.

Good luck with the presentation.
 

The Naked Scientists Forum

Genetics Journal Article
« Reply #1 on: 29/10/2008 18:49:17 »

 

SMF 2.0.10 | SMF © 2015, Simple Machines
SMFAds for Free Forums