The Naked Scientists

The Naked Scientists Forum

Author Topic: Adenosine Deaminase  (Read 5778 times)

Offline Donnah

  • Ma-Donnah
  • Neilep Level Member
  • ******
  • Posts: 1756
    • View Profile
Adenosine Deaminase
« on: 14/09/2003 21:10:22 »
Can someone tell me about adenosine deaminase?  What is it what does it do, interactions, sources...that sort of thing.
« Last Edit: 31/05/2004 05:34:03 by NakedScientist »


 

Offline Ians Daddy

  • Hero Member
  • *****
  • Posts: 532
    • View Profile
Re: Adenosine Deaminase
« Reply #1 on: 14/09/2003 23:23:40 »
Donnah,
I didn't read it in it's entirety, but it sounds serious. You don't know anyone with iot do you?

http://www-personal.umd.umich.edu/~jcthomas/JCTHOMAS/1997%20Case%20Studies/CMarting.html

Hope that helps.
 

Offline Donnah

  • Ma-Donnah
  • Neilep Level Member
  • ******
  • Posts: 1756
    • View Profile
Re: Adenosine Deaminase
« Reply #2 on: 15/09/2003 02:50:30 »
No, just doing research...seems to be a key factor in failing immune systems.  T-cells initiate an immune response and are produced in bone marrow.  Bone marrow transplants seem to "fix" ADA (adenosine deaminase) deficiency to some degree but I haven't yet grasped the connection between T-cells and ADA.
« Last Edit: 15/09/2003 02:59:55 by Donnah »
 

Offline bezoar

  • Hero Member
  • *****
  • Posts: 950
    • View Profile
Re: Adenosine Deaminase
« Reply #3 on: 15/09/2003 04:49:37 »
From what I gather from the article, The lack of ADA causes an increase in other chemicals which are toxic to the lypmphocytes or white blood cells.  Additionally, there is a breakdown in making and repairing DNA.  What is interesting is that I read they are trying to infuse ADA combined with PEG.  I saw tht they are trying this with interferon for treatment for hepatitis as well.  PEG, if I'm not mistaken, is antifreeze.  Somehow I think it results in higher levels of whatever chemical you combine it with and slower excretion.  All this stuff is way over my head.  We need the doctor!
 

The Naked Scientists Forum

Re: Adenosine Deaminase
« Reply #3 on: 15/09/2003 04:49:37 »

 

SMF 2.0.10 | SMF © 2015, Simple Machines
SMFAds for Free Forums