The Naked Scientists

The Naked Scientists Forum

Author Topic: Need help with understanding blood glucose and albumin  (Read 5433 times)

Offline sue1234

  • First timers
  • *
  • Posts: 6
    • View Profile
I have a kind of a long question, as I'm trying to wrap my head around something and actually understand it.  If I understand it better, then I can talk to my doctor about it in a more intelligent way.

What does albumin have to do with blood sugar?  I get low blood sugar all the time, and have for almost 20 years.  I am not a diabetic.  The other problem I have had for the last few years is I am orthostatic intolerant, meaning, if I stand for more than say 5-8 minutes, I feel like fainting.  My heart rate and b/p go up.  It's kind of like I don't have enough blood volume or something.  The doctors can only tell me I have this, but not why.

I read something that said albumin(or protein in the blood(same thing?)) might get diverted in hypoglycemia to become glucose.  Is this true?

If so, does it make sense that chronic hypoglycemia episodes could divert enough albumin to cause chronically low blood volume(specifically the plasma)??

I guess you can see where I'm going with this!  If this is the case, then my orthostatic issues could very well be related back to years of low blood sugar.  I guess getting that under good control could help the orthostatic issues.

Thanks in advance for any explanations!!


 

Offline RD

  • Neilep Level Member
  • ******
  • Posts: 8132
  • Thanked: 53 times
    • View Profile
Need help with understanding blood glucose and albumin
« Reply #1 on: 10/06/2011 01:54:38 »
What does albumin have to do with blood sugar?  I get low blood sugar all the time

Albumin affects the release of insulin ... http://www.ncbi.nlm.nih.gov/pubmed/16029032
Delivering too much insulin at once will cause hypoglycemia.
« Last Edit: 10/06/2011 02:03:14 by RD »
 

Offline sue1234

  • First timers
  • *
  • Posts: 6
    • View Profile
Need help with understanding blood glucose and albumin
« Reply #2 on: 10/06/2011 02:29:50 »
Thanks for the link,however, I interpret it as talking about linking albumin with exogenous insulin for delivery to diabetics.  I am not a diabetic and take no insulin.  In that context, I was wondering what albumin(or protein) has to do with blood sugar. 
 

Offline RD

  • Neilep Level Member
  • ******
  • Posts: 8132
  • Thanked: 53 times
    • View Profile
Need help with understanding blood glucose and albumin
« Reply #3 on: 10/06/2011 03:32:21 »
Thanks for the link,however, I interpret it as talking about linking albumin with exogenous insulin for delivery to diabetics. 

it's also true of endogenous insulin (which is a hormone) ...

Quote
Many hormones, drugs, and other molecules are mostly bound to albumin in the bloodstream and must be released before becoming biologically active.
http://en.wikipedia.org/wiki/Hypoalbuminemia
« Last Edit: 10/06/2011 03:37:52 by RD »
 

The Naked Scientists Forum

Need help with understanding blood glucose and albumin
« Reply #3 on: 10/06/2011 03:32:21 »

 

SMF 2.0.10 | SMF © 2015, Simple Machines
SMFAds for Free Forums