The Naked Scientists

The Naked Scientists Forum

Author Topic: How is immune tolerance achieved?  (Read 1988 times)

Offline cheryl j

  • Neilep Level Member
  • ******
  • Posts: 1460
  • Thanked: 1 times
    • View Profile
How is immune tolerance achieved?
« on: 19/12/2011 21:23:21 »
I believe that before birth and early in childhood the thymus is important in the maturation of T- lymphocytes, and their capacitiy to distingusih between self and non self, but I forget how it works. Are T cells that respond to self-antigens some how eliminated?Or do they never respond to self antigens?
« Last Edit: 20/12/2011 09:42:24 by chris »


 

Offline Nizzle

  • Hero Member
  • *****
  • Posts: 964
  • Thanked: 1 times
  • Extropian by choice!
    • View Profile
    • Carnivorous Plants
Re: immune tolerance
« Reply #1 on: 20/12/2011 07:54:07 »
T-cells that respond to self-antigens are indeed also formed and consequently eliminated, but that's about everything I remembered from my education. It had something to do with the "Major histocompatibility complex" but the exact mechanism should be out there on the interweb somewhere..
« Last Edit: 20/12/2011 07:56:17 by Nizzle »
 

The Naked Scientists Forum

Re: immune tolerance
« Reply #1 on: 20/12/2011 07:54:07 »

 

SMF 2.0.10 | SMF © 2015, Simple Machines
SMFAds for Free Forums
 
Login
Login with username, password and session length