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Author Topic: How does the herpes virus hide when it's inactive?  (Read 4489 times)

Offline thedoc

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How does HSV1 virus, the Herpes simplex virus that causes cold sores, hide between times when itís active?
Asked by Steve Gale, Facebook


                                        Visit the webpage for the podcast in which this question is answered.

 

« Last Edit: 20/03/2012 16:33:22 by _system »


 

Offline thedoc

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How does the herpes virus hide when it's inactive?
« Reply #1 on: 20/03/2012 16:33:22 »
We answered this question on the show...



It hides inside nerve cells.  It exists as a small piece of DNA, which is just the genetic material for the virus, hiding inside the nerve cellís nucleus alongside the DNA in that cell.  As a result, itís out of reach of the immune system and because itís not making any proteins that the cell can display on its surface, the immune system doesnít tend to touch it.  It can then use the genetic recipe book in that DNA to come back to life later, producing new virus particles that go back down the nerve cell, come out on the skin, and produce an infectious lesion that is unsightly, but is also highly infectious and you can pass it on.
« Last Edit: 20/03/2012 16:33:22 by _system »
 

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How does the herpes virus hide when it's inactive?
« Reply #1 on: 20/03/2012 16:33:22 »

 

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