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Author Topic: Does marijuana rewire the brain?  (Read 2692 times)

Offline thedoc

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Does marijuana rewire the brain?
« on: 05/08/2014 18:07:06 »
Long-term marijuana use rewires the brain, making it less
sensitive to the feel-good chemical dopamine...
Read a transcript of the interview by clicking here

or Listen to it now or [download as MP3]
« Last Edit: 05/08/2014 18:07:06 by _system »


 

Offline tkadm30

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Re: Does marijuana rewire the brain?
« Reply #1 on: 29/12/2015 12:19:02 »
CB1 receptors activation by endocannabinoids may affect emotional behavior through cross-talk with dopaminergic D1 receptors. Thus, marijuana is a potential anxiolytic treatment for post-traumatic stress disorder (PTSD).

www.ncbi.nlm.nih.gov/pmc/articles/PMC3156975/

www.sciencedaily.com/releases/2013/05/130514085016.htm
 

Leeroy

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« Reply #2 on: 04/02/2016 17:29:51 »
That is masking the problem, not addressing the root problem that was the failure to cope with the traumatic event.  Coping, understanding, finding meaning, empathizing.  Those are methods for aiding in PTSD.  Not, smoke weed, it will make it better.  Sure, if I have lots of troubles, I can smoke them away and simply not care due to amotivational syndrome courtesy of cannabis use.  But, that isn't the right thing to do.  That's breaking one finger to take your mind off of your finger that was already broken.
 

Offline tkadm30

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Re: None
« Reply #3 on: 07/02/2016 21:06:46 »
That is masking the problem, not addressing the root problem that was the failure to cope with the traumatic event.  Coping, understanding, finding meaning, empathizing.  Those are methods for aiding in PTSD.  Not, smoke weed, it will make it better.  Sure, if I have lots of troubles, I can smoke them away and simply not care due to amotivational syndrome courtesy of cannabis use.  But, that isn't the right thing to do.  That's breaking one finger to take your mind off of your finger that was already broken.

Cannabinoids for PTSD is a emerging therapy to treat the neurocognitive impairments associated with PTSD. Pharmaceuticals applications of endocannabinoid based drugs for PTSD should improve the mental condition without the need of smoking.

http://www.ncbi.nlm.nih.gov/pubmed/23670490
 

Offline tkadm30

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Re: Does marijuana rewire the brain?
« Reply #4 on: 08/02/2016 12:08:40 »
Here is a 2015 study which focus on the role of endocannabinoids in the treatment of hyperarousal symptoms of PTSD. Apparently, the CB1 receptor is a key neurobiological factor in the etiology of PTSD.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268027/

Moreover, a little bit of research on cannabis 'amotivational syndrome' helps to understand how this myth promotes cannabis prohibition:

"While certain strains of medical cannabis may cause short-term fatigue in some patients during use, the concept of an “amotivational syndrome” supposedly caused by cannabis use is not supported by research. Additionally, studies which have claimed to evidence a cause-effect relationship of cannabis use and a lack of motivation have confounding variables, which compromise the validity of results."

http://in-training.org/medical-cannabis-myth-amotivational-syndrome-6905
 

Offline exothermic

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Re: Does marijuana rewire the brain?
« Reply #5 on: 09/02/2016 02:43:09 »
lol... The title and/or implication is extremely misleading, and I am more than willing to bet that the acual study methodologies are flawed at best.


"The researchers used PET brain imaging to look at dopamine production in the striatum of 19 regular cannabis users and 19 non-users of matching age and sex.

The users in the study had all experienced psychotic-like symptoms while smoking the drug, such as experiencing strange sensations or having bizarre thoughts like feeling as though they are being threatened by an unknown force."


~~

 

Offline tkadm30

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Re: Does marijuana rewire the brain?
« Reply #6 on: 09/02/2016 12:55:20 »
lol... The title and/or implication is extremely misleading, and I am more than willing to bet that the acual study methodologies are flawed at best.

Cannabis science is muzzled by prohibition. In reality, medical cannabis research will benefit from legalization as it open the door to new treatments. Doctors will not like it but the scientific evidences should prove that cannabis is a harmless substance with medical properties to treat a range of clinical conditions.
 

Offline exothermic

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Re: Does marijuana rewire the brain?
« Reply #7 on: 15/02/2016 01:00:17 »
"the scientific evidences should prove that cannabis is a harmless substance with medical properties to treat a range of clinical conditions."

Yeah, and despite locking millions of non-violent cannabis offenders in prison since 1927.... the government has been well aware of the medicinal potential of cannabis for years - hence their cannabinoid patent from the 80's..... Talk about a conundrum.
 

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Re: Does marijuana rewire the brain?
« Reply #7 on: 15/02/2016 01:00:17 »

 

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