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Author Topic: When transcribing DNA how do we know which way round it is?  (Read 681 times)

Offline thedoc

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Peter Palmer asked the Naked Scientists:
Since both DNA strands have a 3' end, and I know of no means a cell can differentiate sense from anti-sense, (other than potentially distance to the centromere), is there a reason a reverse complement incorporating the combined promoter and starter sequences is unlikely, in order to avoid spurious primary transciptions?

What do you think?
« Last Edit: 29/09/2015 08:50:01 by _system »


Offline evan_au

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Reading complementary DNA is likely to end up hitting a "STOP" codon fairly quickly?
...But this would still leave a lot of short junk RNA sequences floating around...

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