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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6454561 times)

Offline demografx

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« Reply #13325 on: 24/05/2011 23:55:27 »

It sounds crazy to think autologous semen could pose a threat, but it may be possible to have an anaphylactic response, so please be careful if you decide to try this [sublingual immunotherapy].


Thank you for that cautionary note!
« Last Edit: 24/05/2011 23:57:15 by demografx »
 

Offline demografx

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« Reply #13326 on: 24/05/2011 23:59:47 »
 

Offline John21

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« Reply #13327 on: 25/05/2011 00:33:38 »
Animus, I just watched the show from the link. I think that you presented your case in a rational intelligent manner. It is courageous to put such an unusual personal situation in front of cameras. Very well done!
 

Offline Animus

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« Reply #13328 on: 25/05/2011 07:19:58 »
Animus, I just watched the show from the link. I think that you presented your case in a rational intelligent manner. It is courageous to put such an unusual personal situation in front of cameras. Very well done!

Thank you, John. TLC did a great job. They did 2-1/2 days of filming for about 12 minutes of air time. So they really put a lot of work into it.
« Last Edit: 25/05/2011 08:06:13 by Animus »
 

Offline alui

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« Reply #13329 on: 25/05/2011 10:19:12 »
bonjour,
je pense avoir les symptomes de POI...
parlez vous français sur ce forum?
merci
 

Offline Vandemolen3

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« Reply #13330 on: 25/05/2011 12:00:39 »
Yesterday I had an O. Today is day 1. And I feel better than normal. I think I have 25 % less POIS. But I don't know in how far this is the effect of injections. Because I was eroused a very long time and then I had the O. In this case there is always less seed in the sperm. That could be a reason. And the other thing is that I just came back from a holiday from Asia (lot's of vitamin D). I will try it about a week with a quick O. I will let you know. But I can't wait to get my new injection about 3 weeks.
 

Offline demografx

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« Reply #13331 on: 25/05/2011 16:34:27 »

bonjour,

je pense avoir les symptomes de POI...
parlez vous français sur ce forum?
merci


Oui. Pas moi, mais deux, trois autres. :)
 

Offline daveman

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« Reply #13332 on: 25/05/2011 17:11:56 »

bonjour,

je pense avoir les symptomes de POI...
parlez vous français sur ce forum?
merci


Oui. Pas moi, mais deux, trois autres. :)

Peut-être je peux mettre un thread français sur l'autre forum, pour ceux qui ne parlent pas anglais. Peut-être les participants français peuvent traduire certaines choses pour les autres utilisateurs.... Comme une expérience de test :)
 

Offline daveman

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« Reply #13333 on: 25/05/2011 17:53:28 »
A french thread is opened at the new forum here at the new forum

It is an experiment. Others have asked for threads in other languages, and up until now it hasn't been done for a few reasons:

  • If English can be spoken it better for everybody
  • Translators would be needed so that non-english speaking people could benefit from the rest of the forum
  • The threads in other languages would become isolated from the rest
  • There'd have to be a space for every new language that comes to the forum

Mostly it's a problem of resources, but if there are people who don't speak ANY English, I think our community should try to help them find solutions. So let's give it a try.

Thanks.

 

Offline Vincent M

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« Reply #13334 on: 25/05/2011 22:23:00 »
Demo, personally I think your remaining 20% is most likely caused by semen and if you eliminated semen production you would eliminate that 20%. However I base that mainly on Animus's successful surgery and his case is still only one case no matter how successful it was meaning there may be a possibility it won't work for everyone with POIS.

On a different note, but not entirely, Starsky posted this on the new forum about fenugreek. I think it could be pretty important info:
--------
"OBJECTIVE: The objective of this study was to evaluate the potential antifertility activity of feeding diets containing 30% fenugreek seeds to male and female white New Zealand rabbits. RESULTS: The data presented in this study clearly demonstrate an antifertility effect of fenugreek seeds in the female rabbits and more of a toxicity effect in the male rabbits. In males, testis weight was reduced, with evident damage to the seminiferous tubules and interstitial tissues as shown by the histopathology of testis tissue sections. In addition, the plasma concentration of the androgen hormone and sperm concentrations were halved in the treated animals. In the case of the females, there was evidence of a significant reduction of developing fetuses as observed by reductions of both fetal and placental weights at 20 days of gestation and of the litter size. This was further supported histopathologically by the observed proliferative changes of the endometrial glands. The circulating plasma progesterone concentrations at 10 and 20 days of gestation significantly increased with no significant effect on the prebreeding estrogen concentrations in the treated animals."
--------
Perhaps this means fenugreek reduces POIS by reducing sperm production. Demo, did you say you tried fenugreek? If it didn't work for you maybe it's because you weren't producing sperm at the time.
« Last Edit: 25/05/2011 22:37:47 by Vincent Marcus »
 

Offline horizon

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« Reply #13335 on: 25/05/2011 23:08:24 »
I'm definitely having an allergic reaction to it (unless some negative placebo is possible?).  The allergist test also induced POIS.   

yes i think they called it nacebo
 

Offline Habibou

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« Reply #13336 on: 25/05/2011 23:17:55 »

bonjour,

je pense avoir les symptomes de POI...
parlez vous français sur ce forum?
merci


Oui. Pas moi, mais deux, trois autres. :)

Hahaha Demo , congratulations !
Oui, je suis français !!!
 

Offline Vandemolen3

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« Reply #13337 on: 25/05/2011 23:55:00 »
Recent interview with Dr. Waldinger on an independent website of the university where he is a professor:

http://www.dub.uu.nl/content/sperma-allergie-gaat-de-wereld-over

Google Translate:
http://translate.google.nl/translate?u=http%3A%2F%2Fwww.dub.uu.nl%2Fcontent%2Fsperma-allergie-gaat-de-wereld-over&sl=nl&tl=en&hl=&ie=UTF-8

Quote
Meanwhile, Waldinger and colleagues of Immunopharmacology continue his research into the cause of POIS. "We are now at the molecular level to the sperm look. What is not good there? From studies in humans, we now have on basic research."
« Last Edit: 26/05/2011 00:01:14 by Vandemolen3 »
 

Offline POIS-SUFFERER

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« Reply #13338 on: 26/05/2011 00:12:54 »
So with fenugreek seeds, I read soak in water overnight, not much info?

Crush them a bit then soak?
How much water?
Do I drink the water in the morning?
Do I eat the seeds in the morning?
Who choose the # 10-20?

Any know overdose levels?

PS

Demo, personally I think your remaining 20% is most likely caused by semen and if you eliminated semen production you would eliminate that 20%. However I base that mainly on Animus's successful surgery and his case is still only one case no matter how successful it was meaning there may be a possibility it won't work for everyone with POIS.

On a different note, but not entirely, Starsky posted this on the new forum about fenugreek. I think it could be pretty important info:
--------
"OBJECTIVE: The objective of this study was to evaluate the potential antifertility activity of feeding diets containing 30% fenugreek seeds to male and female white New Zealand rabbits. RESULTS: The data presented in this study clearly demonstrate an antifertility effect of fenugreek seeds in the female rabbits and more of a toxicity effect in the male rabbits. In males, testis weight was reduced, with evident damage to the seminiferous tubules and interstitial tissues as shown by the histopathology of testis tissue sections. In addition, the plasma concentration of the androgen hormone and sperm concentrations were halved in the treated animals. In the case of the females, there was evidence of a significant reduction of developing fetuses as observed by reductions of both fetal and placental weights at 20 days of gestation and of the litter size. This was further supported histopathologically by the observed proliferative changes of the endometrial glands. The circulating plasma progesterone concentrations at 10 and 20 days of gestation significantly increased with no significant effect on the prebreeding estrogen concentrations in the treated animals."
--------
Perhaps this means fenugreek reduces POIS by reducing sperm production. Demo, did you say you tried fenugreek? If it didn't work for you maybe it's because you weren't producing sperm at the time.
 

Offline Willem

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« Reply #13339 on: 26/05/2011 00:20:14 »
I'm definitely having an allergic reaction to it (unless some negative placebo is possible?).  The allergist test also induced POIS.   

yes i think they called it nacebo

Wow.  Never heard of nocebo.  Thanks for the tip.

http://en.wikipedia.org/wiki/Nocebo [nofollow]

I think I'll join a hypochondriac forum just to hedge my bets.  Ha ha ha. 
 

Offline CertainlyPOIS

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« Reply #13340 on: 26/05/2011 03:29:25 »
Recent interview with Dr. Waldinger on an independent website of the university where he is a professor:

http://www.dub.uu.nl/content/sperma-allergie-gaat-de-wereld-over

Google Translate:
http://translate.google.nl/translate?u=http%3A%2F%2Fwww.dub.uu.nl%2Fcontent%2Fsperma-allergie-gaat-de-wereld-over&sl=nl&tl=en&hl=&ie=UTF-8

Quote
Meanwhile, Waldinger and colleagues of Immunopharmacology continue his research into the cause of POIS. "We are now at the molecular level to the sperm look. What is not good there? From studies in humans, we now have on basic research."

That last two sentence is confusing, those that mean he is looking at the sperm to see what is wrong.
 

Offline CertainlyPOIS

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« Reply #13341 on: 26/05/2011 03:31:27 »

Perhaps this means fenugreek reduces POIS by reducing sperm production. Demo, did you say you tried fenugreek? If it didn't work for you maybe it's because you weren't producing sperm at the time.

it also increases progesterone; progesterone reduces effect of  immune reaction a
 

Offline CertainlyPOIS

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« Reply #13342 on: 26/05/2011 03:32:56 »

vandemolen, if i was to come over to netherlands, how long is dr waldingers waiting list.


CC, he just wrote to me that he could see Green at the end of July.
I was asking for two years down line if i have to move just trying to gage how quickly i will see him.
« Last Edit: 26/05/2011 03:41:06 by CCconfucius »
 

Offline Vandemolen3

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« Reply #13343 on: 26/05/2011 10:13:22 »
That last two sentence is confusing, those that mean he is looking at the sperm to see what is wrong.
It's a bad translation of Google. But you are right.
 

Offline Habibou

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« Reply #13344 on: 26/05/2011 11:39:28 »
Recent interview with Dr. Waldinger on an independent website of the university where he is a professor:

http://www.dub.uu.nl/content/sperma-allergie-gaat-de-wereld-over

Google Translate:
http://translate.google.nl/translate?u=http%3A%2F%2Fwww.dub.uu.nl%2Fcontent%2Fsperma-allergie-gaat-de-wereld-over&sl=nl&tl=en&hl=&ie=UTF-8

Quote
Meanwhile, Waldinger and colleagues of Immunopharmacology continue his research into the cause of POIS. "We are now at the molecular level to the sperm look. What is not good there? From studies in humans, we now have on basic research."

That's newswhorthy ! It would be great we are allowed to know where are the researches months by months...
 

Offline rock27

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« Reply #13345 on: 26/05/2011 15:16:39 »
Quote
Meanwhile, Waldinger and colleagues of Immunopharmacology continue his research into the cause of POIS. "We are now at the molecular level to the sperm look. What is not good there? From studies in humans, we now have on basic research."

Quote
That's newswhorthy ! It would be great we are allowed to know where are the researches months by months...

I got scared when I first read this.
But I think he is searching for the exact component of the sperm we are allergic to, so to to make the remedy easier. Good job he's gotten more researchers on his team!
 

Offline demografx

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« Reply #13346 on: 26/05/2011 19:22:42 »

Demo, personally I think your remaining 20% is most likely caused by semen and if you eliminated semen production you would eliminate that 20%. However I base that mainly on Animus's successful surgery and his case is still only one case no matter how successful it was meaning there may be a possibility it won't work for everyone with POIS....
...
...
Perhaps this means fenugreek reduces POIS by reducing sperm production. Demo, did you say you tried fenugreek? If it didn't work for you maybe it's because you weren't producing sperm at the time.


VM, thank you!

And I will try fenugreek, daveman also suggested it.

But since I have Zero-sperm now, I wonder if it could still work?
« Last Edit: 26/05/2011 19:38:56 by demografx »
 

Offline demografx

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« Reply #13347 on: 26/05/2011 19:41:46 »
Nacebo? Wow, this place is always teaching me something new!
 

Offline daveman

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« Reply #13348 on: 26/05/2011 22:48:27 »

Demo, personally I think your remaining 20% is most likely caused by semen and if you eliminated semen production you would eliminate that 20%. However I base that mainly on Animus's successful surgery and his case is still only one case no matter how successful it was meaning there may be a possibility it won't work for everyone with POIS....
...
...
Perhaps this means fenugreek reduces POIS by reducing sperm production. Demo, did you say you tried fenugreek? If it didn't work for you maybe it's because you weren't producing sperm at the time.


VM, thank you!

And I will try fenugreek, daveman also suggested it.

But since I have Zero-sperm now, I wonder if it could still work?

I was thinking more about Lauracostis's theory which involves the whole hormonal chain reaction more than the sperm itself.

Perhaps the fenugreek may not contribute enough to acheive what he was speaking about, but since the progestin caused problems for you maybe we can give it a second more agreeable try with something a little less potent.

640mg 1 - 2 hrs before and one right after. On a full stomach works best they say.

Think it needs maintenance on non-O days. Same dose I think, one in the morning one at night.
 

Offline demografx

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« Reply #13349 on: 27/05/2011 01:32:14 »
From our friend, Stefanie, at NORD


Dear Demo,

Despite what initially appeared to be enthusiasm on the part of Vesselin Dimov, MD, University of Chicago, and his colleague, Againdra K. Bewtra, MD, Creighton University,  I have not heard back from either of them after Dr. Dimov contacted me.
I did make two attempts at follow-up, but to no avail.  They both have excellent credentials, but they apparently are not interested in pursuing evaluations and testing.

There are others on my growing list of researchers who may be quite interested in evaluating men from the forum. So -- it's onward and upward!  There is no turning back! :-)

I will let you know as I hear from other physicians/researchers.

In the meantime, I understand that there have been discussions about a research grant sponsored by your group.  Excellent!!!!!  I am going to be sending information to you about NORD's research grant program for rare disorders -- our program may suit your needs perfectly! :-)





Sincerely,
 
Stefanie Putkowski, RN, BSN
Clinical Information Specialist
Research Program Administrator
National Organization for Rare Disorders
55 Kenosia Avenue
PO Box 1968
Danbury, CT 06813-1968
Phone: 203.744.0100
Fax: 203.798.2291
email: rn@rarediseases.org
http://www.rarediseases.org
 
Join our online community
http://nord.clinicahealth.com/
 
NORD Subscription Service
http://www.rarediseases.org/programs/subscriptions

 
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