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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6454197 times)

Offline Hoping

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« Reply #13750 on: 24/06/2011 20:58:11 »


The main symptoms i'm experiancing are a complete lack of motivation and energy to the point where i stopped working and dropped any and all of my hobbies.  I've been attempting to do some digging and it seems that those 3 fit fairly well with low testosterone which i know some people here have had issues with as well but my blood tests have all come back normal so my doctor disregarded my concern.

over the past 3 years i've attempted about 6 different types of anti-depressants as well as many different types of therapy and seen many psychologists but nothing has helped even in the slightest.  I've been given a clean mental bill of health multiple times and am concerned its a physical/hormone issue but my family doctor has pretty much given up at this point

about 3 times in the last 3 years i've had complete relief from these new symptoms but its only been for 24 hours and i can never find a connection, any suggestions would be be greatly appreciated, thanks.

what antidepressants have you tried? wellbutrin is the closests i've gotten to curing this nightmare. i've tried all the ssris pretty much and they made things worse. i think my problem stems from low dopamine

I'd have to check my exact list but the 4 i can remember now are Pristiq(desvenlafaxine),  paroxetine, Prozzac and Wellbrutrin.  The first day or 2 of trying the welbutrin gave me complete relief of those new symptoms, i felt 100% better, was a night to day comparison.  Unfortunately that left after 24 hours and never came back in my next 10 weeks on the drug regardless of doubling and 2.5x the dose.  

Honestly i'm no expert but after trying these various anti depressants for over a year i've convinced myself its not standard depression, i've had depression in the past many years ago and this just doesn't feel the same.  Not only that but from i understand about antidepressants is they work over a period of time so for me to be relieved 100% within an hour or so of taking it makes me feel it was more likely some sort of other chemical reaction unrelated to depression.

were you on wellbutrin by itself? or was it anadjunct to another antidepressant?

I just wanted to chime in that I've been taking 150mg wellbutrin for the past two or three years. This is a fairly low dosage. I feel like I have more energy while on the drug. I feel like my "lows" aren't quite as low. POIS-induced depression and mood swings are still a big problem for me, but the wellbutrin may have lessend them -- it's difficult to remember my pre-wellbutrin self.
Connor and Spence --> what dosage did you try?
 

Offline Mer

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« Reply #13751 on: 24/06/2011 22:18:15 »
I just noticed after being sexually excited and urinating a minute after, I found my body very cold and started to have brain fog.. anyone had the same experience?
I didn`t ejaculate but have seen the transparent liquid coming out. Only after urinating I felt cold and etc.
 

Offline demografx

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« Reply #13752 on: 25/06/2011 04:08:26 »
For all our new visitors and friends!

We started a POIS Research Fund to boost our attack on The POIS Monster! Explained here:
http://poiscenter.com/forums/index.php?topic=125.0

We raised $2,150 in just the first 2 weeks, with much more pledged!

And your POIS fund donation is most welcome here:
http://rarediseases.org/about/support/research-donations

Our new POIS Forum - architectural genius: "daveman" - for detailed subject-by-subject discussion!
http://www.POISCenter.com/forums/index.php

Our 4-year-old POIS thread here at Naked Science Forum will also always remain open for newcomers, for general unstructured discussion, and historical research of the 10,000+ postings here since 2007.



« Last Edit: 25/06/2011 04:53:57 by demografx »
 

Offline silverandcol

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Offline John21

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« Reply #13755 on: 25/06/2011 19:09:14 »
I donated $100 towards the NORD research fund, I think. I did not receive a confirmation email so I am not exactly sure that it went through. Maybe they only process the transactions during the week?

POIS Update:
I have been taking fenugreek capsules daily: at night before bed. Someone posted a link to a study showing a possible link between taking fenugreek and lowered sperm production. On that basis, plus the fact that it has other positive effects for me I am taking it at night, partially as a defense against NEs.

A few weeks ago I had an NE. When I got up to urinate it did seem to be easier to get the stream going than what is typical, but perhaps that was just my perception. I immediately ate some sweet potatoes and for the next two weeks I ate that plus other anti-inflammatory foods such as salmon, blueberries, garlic, etc. For those two weeks I had zero symptoms. After two weeks I did have some burnout, which may or may not have been related to the NE. Coincidentally I had forgotten to take the fenugreek when that happened, and upon resumption (plus lots of anti-inflammatory foods) the burnout lifted. So between these two possible defences I think I have something that seems to be working. It is currently untested on an O. I have since upped my fenugreek to two capsules nightly, and I feel good on it. Hey maybe I can start dating soon!

« Last Edit: 25/06/2011 19:11:35 by John21 »
 

Offline demografx

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« Reply #13756 on: 25/06/2011 22:29:35 »

I donated $100 towards the NORD research fund.



John, our first and longest-standing member, thank you very much !!
 

Offline Pharaoh

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« Reply #13757 on: 26/06/2011 00:18:57 »
POIS Update:

The Allegra + Cyproheptadine (anti-histamines) treatment definitely does not work.  Furthermore, I was able to recover much quicker with a daily complete multi-vitamin + cardio/weight training.  I had an O on Wednesday, and the symptoms have been sever, including back muscle pain that had me awake almost all night.  Today, after dragging myself out of bed, I decided to hit the gym for a cardio session.  Couldn't do any weights because I've been suffering from shoulder pain, and following the O, back pain.  I'm going to see a specialist next week to check if it's tendinitis or bursitis, or something else.  But, back to the cardio session.  Before going I took Jack3d, a "nitric oxide" pre-workout supplement that gives you a serious boost.  I did 1 hr of high intensity walking with alternating incline, then took 1 Mind Body & Spirit (rhodiola rosea) and Energy Reserves (same company).  I was still feeling a bit fatigued, and not the post-workout kind, but the POIS kind.  Then I received my order of Controlled Labs Orange Triad, a multi-vitamin, joint, digestion & immune formula.  I ordered it after running out of GNC mega men sport, and because I read it would help with the joint pain.  Incredibly, I started feeling so much better after taking 1 tablet.  The directions recommend starting with 1 to assess your individual tolerance to the formula.  And then taking 3 with breakfast and 3 with dinner daily.   I also had an iced coffee and a met-rx big colossal protein bar.  The only difference between the last few days since the O and today is the Orange Triad.  Plus, I think having an O while going off a multi-vitamin may have been an issue.  Btw, the POIS symptoms haven't completely left, but I had energy, and didn't suffer any social-anxiety when I went out later in the day. 

So, in conclusion, I learned that a good multi-vitamin is a must when dealing with POIS. 

Btw, I've come across a number of studies using psychotropic substances to deal with depression and other mental disorders, including autism.  I've always been interested in DMT, and some of you may have seen the documentary "The Spirit Molecule" about the use of DMT by ancient cultures (Egyptians) and shamans (in the form of ayahuasca) to stimulate the pineal gland and trigger a metaphysical/transcendental experience/state.  There is an excellent National Geographic story written by a woman who used ayahuasca under the guidance of Shamans in South America to overcome depression and deal with other illnesses.  I strongly suggest you read it: http://www.nationalgeographic.com/adventure/0603/features/peru.html [nofollow].

After doing some research on the use of these type of substances I came across the Heffter Institute: http://www.heffter.org/about.htm [nofollow].  This is a very serious research institute funding "research at the frontiers of the mind" with medical doctors and professors from the top universities.  They're looking into the use of psychotropic substances as pharmacological uses.  I've actually contacted a few at the Johns Hopkins Medical School to volunteer for any current or future studies after reading one of their papers in the Journal of Psychopharmacology: "Mystical-type experiences occasioned by psilocybin mediate the attribution of personal meaning and spiritual significance 14 months later."  The title looks bizarre, but the authors are all senior professors at Johns Hopkins and the Journal is one of the top in its field.  Psilocybin is the psychotropic substance found in "magic" mushrooms and has been used for centuries for religious purposes.  I'm doing what I can to convince these doctors to administer dosages of this, or DMT, as a possible cure for POIS.  There is definitely a "trip," but many people have returned feeling "healed" from both psychological and physical ailments.  Furthermore, theses scientists are studying the neurological changes that these experiences cause.  One doctor, a biochemist, has already stated that they do not have any current studies that I would be suitable for, but I'm looking forward to the response of another who is psychiatrist.  Will keep you informed.
 

Offline Pharaoh

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« Reply #13758 on: 26/06/2011 00:40:37 »

POIS Update:
I have been taking fenugreek capsules daily: at night before bed. Someone posted a link to a study showing a possible link between taking fenugreek and lowered sperm production. On that basis, plus the fact that it has other positive effects for me I am taking it at night, partially as a defense against NEs.


Hi John21,

Thanks for sharing that with us.  I saw a study linking fenugreek with increased libido in men (http://www.cbsnews.com/8301-504763_162-20072589-10391704.html [nofollow]).  So, I'm curious as to why it would reduce sperm production.  I know the testosterone I'm taking is supposed to reduce sperm production as well, although I can attest that it simultaneously increases libido.  So, there seems to be a tradeoff.  Have you felt an increased libido?
 

Offline John21

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« Reply #13759 on: 26/06/2011 10:38:02 »

POIS Update:
I have been taking fenugreek capsules daily: at night before bed. Someone posted a link to a study showing a possible link between taking fenugreek and lowered sperm production. On that basis, plus the fact that it has other positive effects for me I am taking it at night, partially as a defense against NEs.


Hi John21,

Thanks for sharing that with us.  I saw a study linking fenugreek with increased libido in men (http://www.cbsnews.com/8301-504763_162-20072589-10391704.html).  So, I'm curious as to why it would reduce sperm production.  I know the testosterone I'm taking is supposed to reduce sperm production as well, although I can attest that it simultaneously increases libido.  So, there seems to be a tradeoff.  Have you felt an increased libido?

Perhaps, I've had sex on the mind lately, it could be influenced by the fenugreek. But I am not sexually active so I may not be the best person to comment on that.
 

Offline demografx

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Offline daveman

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« Reply #13761 on: 26/06/2011 21:03:59 »
We are officially in the NORD (National Organization for Rare Disorders) database. The link to our entry is http://www.rarediseases.org/rare-disease-information/organizations/byID/3136/viewDetail

The presence of our data here will be very helpful on various levels, including greater exposure to potential researchers and donors alike.

Also, we are aware of the difficulty involved in finding our forums. With this entry, because of the high number of visits that NORD receives it will help capture even more new members, who are most important to us. Each one will be one step closer to real relief.

 

Offline demografx

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« Reply #13762 on: 26/06/2011 22:28:39 »


Dave, thank you, and Congratulations To Us All!!!
 

Offline Omen 30

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« Reply #13763 on: 27/06/2011 09:39:19 »
I just noticed after being sexually excited and urinating a minute after, I found my body very cold and started to have brain fog.. anyone had the same experience?
I didn`t ejaculate but have seen the transparent liquid coming out. Only after urinating I felt cold and etc.
i experienced the same thing last night...i was sexually exited and i didnt ejeculate but this transperent pre cum came out...i started getting the normal pois symtoms not as serious as i get in ejaculation but ya it were there...so after that i went for a proper ejaculation cause i know it will take around 4days to a week to get normal...oh what a messy life...i was going fine for the last 2 weeks...i think i shouldnt get so much sexually exited also...anyways i have stopped having ejaculation often,just once a month...to lead a better life..but now i have to take care about sexual arousals also...bye friends...
« Last Edit: 27/06/2011 14:34:31 by bitu8489 »
 

Offline Starsky

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« Reply #13764 on: 27/06/2011 17:29:51 »
I used Fenugreek for about 1 week, i dont know how but it increases the semen volume.
 

Offline demografx

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« Reply #13765 on: 27/06/2011 21:27:20 »
Amazing, Starsky, that's what testosterone does for me, and in turn that convinces me of my pet theory that the faster semen regenerates, the less POIS there is.

Speculation.
 

Offline Pharaoh

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« Reply #13766 on: 27/06/2011 23:02:42 »
Quick Question:

Does anyone notice that they develop a mild amblyopia (lazy eye) during POIS?  I recognize that my left eye is a bit lazy during POIS only.  Btw, wikipedia states:

Amblyopia means that visual stimulation either fails to transmit or is poorly transmitted through the optic nerve to the brain for a continuous period of time.  Amblyopia can be caused by deprivation of vision early in life by vision-obstructing disorders such as congenital cataracts, by strabismus (misaligned eyes), anisometropia (different degrees of myopia or hypermetropia in each eye), or by a significant amount of astigmatism in one or both eyes.

Just wondering what your take is on this and why.  My eyesight is perfect and I've never had any issues with it.  Of course, during POIS I have trouble focusing visually and a sensitivity to light.  Wondering how an allergic reaction can cause this condition. 

Thanks.
 

Offline Starsky

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« Reply #13767 on: 28/06/2011 00:04:44 »
I used Fenugreek for about 1 week, i dont know how but it increases the semen volume.
Amazing, Starsky, that's what testosterone does for me, and in turn that convinces me of my pet theory that the faster semen regenerates, the less POIS there is.

Speculation.

But fenugreek makes my POIS somehow weird. I feel some sort of numbness of my brain. Cant really describe it, the pois feeling is diferent, i can be more active but it gives me a unpleasent fealing.
 

Offline demografx

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« Reply #13768 on: 28/06/2011 00:26:51 »
Starsky, yes, I've heard that complaint before.
 

Offline demografx

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« Reply #13769 on: 28/06/2011 00:33:09 »




Research Fund Total: $2,275.00
Please read about it at: http://poiscenter.com/forums/index.php?PHPSESSID=97a0a767229bfcd7b6822ec05c6c0160&topic=125.0
Then help yourself by donating here: http://www.rarediseases.org/about/support/research-donations/fg_base_view_p3



Thank you very much, everyone!!




 

Offline spence23

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« Reply #13770 on: 28/06/2011 09:21:10 »


The main symptoms i'm experiancing are a complete lack of motivation and energy to the point where i stopped working and dropped any and all of my hobbies.  I've been attempting to do some digging and it seems that those 3 fit fairly well with low testosterone which i know some people here have had issues with as well but my blood tests have all come back normal so my doctor disregarded my concern.

over the past 3 years i've attempted about 6 different types of anti-depressants as well as many different types of therapy and seen many psychologists but nothing has helped even in the slightest.  I've been given a clean mental bill of health multiple times and am concerned its a physical/hormone issue but my family doctor has pretty much given up at this point

about 3 times in the last 3 years i've had complete relief from these new symptoms but its only been for 24 hours and i can never find a connection, any suggestions would be be greatly appreciated, thanks.

what antidepressants have you tried? wellbutrin is the closests i've gotten to curing this nightmare. i've tried all the ssris pretty much and they made things worse. i think my problem stems from low dopamine

I'd have to check my exact list but the 4 i can remember now are Pristiq(desvenlafaxine),  paroxetine, Prozzac and Wellbrutrin.  The first day or 2 of trying the welbutrin gave me complete relief of those new symptoms, i felt 100% better, was a night to day comparison.  Unfortunately that left after 24 hours and never came back in my next 10 weeks on the drug regardless of doubling and 2.5x the dose.  

Honestly i'm no expert but after trying these various anti depressants for over a year i've convinced myself its not standard depression, i've had depression in the past many years ago and this just doesn't feel the same.  Not only that but from i understand about antidepressants is they work over a period of time so for me to be relieved 100% within an hour or so of taking it makes me feel it was more likely some sort of other chemical reaction unrelated to depression.

were you on wellbutrin by itself? or was it anadjunct to another antidepressant?
I only took the wellbrutrin by itself, i've never combined any of the anti-depressants with any other additive before.  Hoping to answer your question if i remember correctly 150mg was the minimum dosage for wellbrutrin.  I was up to take 2-300mg tablets a day (600 total) before i stopped after about 2 months.
 

Offline Starsky

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« Reply #13771 on: 28/06/2011 13:35:35 »
Why did you stopped?
 

Offline jivetalk

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« Reply #13772 on: 28/06/2011 15:52:02 »
Hi everyone,

I'm really just curious. Given than Waldinger has effectively found a 'Treatment' for POIS, i.e. Allergy Injections.
Why are we not all rushing out to our local Dr's and Allergists shoving the Waldinger Papers in their faces and saying 'now stick me with my Semen!'

Is there something I am missing here? The papers have certainly given me the courage now to talk to my GP and ask for a referal to an allergist..


P.S - I myself are still trying all sorts of Alternative..treatments, Apple Cider Vinegar, Garlic Pills, Ginko Biloba...Nothing seems to be giving me the 'relief' I'm looking for though..

 

Offline jivetalk

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« Reply #13773 on: 28/06/2011 15:54:22 »
I just noticed after being sexually excited and urinating a minute after, I found my body very cold and started to have brain fog.. anyone had the same experience?
I didn`t ejaculate but have seen the transparent liquid coming out. Only after urinating I felt cold and etc.

Mar, I definitely get the same thing at times. Really Wierd.

OMG - I am SO Sick of this Damn POIS! There. I feel better.
 

Offline Starsky

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« Reply #13774 on: 28/06/2011 16:59:18 »
Hi everyone,

I'm really just curious. Given than Waldinger has effectively found a 'Treatment' for POIS, i.e. Allergy Injections.
Why are we not all rushing out to our local Dr's and Allergists shoving the Waldinger Papers in their faces and saying 'now stick me with my Semen!'



I tried that, but none of them will do that:
autologus ijections are very rare and its just the testing phase, i think in a few years it will be possible
 

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« Reply #13774 on: 28/06/2011 16:59:18 »

 

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