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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6448455 times)

Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1625 on: 17/10/2008 00:44:16 »
Thanks B_Jim, I am hoping very much indeed that fenugreek keeps working for me :)

Great summary of fenugreek's uses, I agree that the reported ability of oxytocin to influence social behaviour is incredible.

Oxytocin nasal sprays are being used by mothers of autistic children to help them socialise more normally, apparently they are very effective!

It makes me wonder if POIS actually makes our brains somewhat autistic temporarily, I have heard that autism is a sliding scale, it can be measured from normal to shy to Aspergers syndrome, and eventually to full-blown autism.

Quote
Seems very plausible that this would work. I guess it more simulates an environment between two lovers that are realy into each other.

Good point Imre1 - you could well be right, earlier in the thread I seem to remember people discussing that the quality of the orgasm had a direct effect on how much they were subsequently affected by POIS.
 

Offline Chewbacca

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1626 on: 17/10/2008 01:59:46 »
Guys!!!!!I just read a very interesting article. It's about how drugs like Levitra, Cialis, and Viagra increase the levels of oxytocin in the brain during genital stimulation. What does this mean? Well....if Hurry is trying a supplement that increases the level of oxytocin and it is working for him that would suggest oxytocin imbalance as a possible cause for POIS. If levitra causes an increase of oxytocin during sexual stimulation that also points to oxytocin imbalance as a possible cause for POIS. I'm curious and hopeful to see how things pan out for Hurry. But I think the oxytocin hypothesis is worth investigating in detail since levitra seems to alleviate some symptoms of POIS and apparently so does fenugreek....both of which effect levels of oxytocin!!!! The only question is why does levitra work and not cialis? Could be individaul biochemical differences. Could also be differences in the drugs themselves. However, this all seems very promissing. Nice job Hurry! below is where i found the article. -chewbacca

http://209.85.173.104/search?q=cache:bAmX5M5eZ0wJ:www.news.wisc.edu/14034+does+levitra+increase+levels+of+oxytocin%3F&hl=en&ct=clnk&cd=7&gl=us [nofollow]
 

Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1627 on: 17/10/2008 03:24:26 »
B_Jim: What is an IG diet?
 

Offline Whoa

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1628 on: 17/10/2008 09:32:56 »
I've definitely had this for a few years. I'm 30 now, and started masturbating up to 7 times a day (and no less than 2 times a day) beginning at age 14. Back then, I didn't have any symptoms of POIS except when I hit upwards of 7 orgasms in one day. I just figured that was what happened when you overdid it.

Fast forward to my mid-20's. After ejaculating I increasingly felt very weak, tired, dehydrated, my testicles felt sore and empty, and my voice cracked and became higher pitched than normal - like an old man's voice - this lasted for a couple days usually. It seemed like, the more and more my balls "filled back up", the symptoms disappeared - I felt more mental clarity, physical strength, energy, happiness, and confidence.

I should also point out: It seems like the more awesome the splash, the worse the sickness. So when I blast a load six to twelve feet I might as well call in sick for work. If it's a weak one, then I'm probably going to be fine within an hour or two. If it were a weak one, but I rub another one out within a short period of time, again it's guaranteed sickness.

While I've never had trouble getting it up, I've always had issues climaxing during intercourse - this was probably due to anxiety, said my doctor, and she prescribed me Levitra - which is why I felt obliged to register and post here today. On Levitra, I can confirm that the POIS symptoms were lessened dramatically post-orgasm. Even after an awesome load, I can still get up and do things. I don't feel paralyzed. However, I've never masturbated with Levitra and only used it for a short while until I was comfortable with my girlfriend - So my testing was limited.

One other thing I've noticed is that I will work out really heavy one day (at the gym and not my on penis). The next day I will indulge on my libido and ejaculate after perhaps 2-3 minutes of masturbation or 15 minutes of sex. Immediately after ejaculating I get a feeling of strong relaxation and relief, then about 5-10 minutes later the muscles I worked out at the gym the day before become extremely sore. Maybe they were even a little sore before ejaculating; however, they are extremely sore afterward. By not having an orgasm, I can literally prevent my muscles from getting very sore if at all.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1629 on: 17/10/2008 19:17:08 »
WHOA! Clever name! And WELCOME to The POIS Forum! Sit back, grab some popcorn and watch our Forum-member girlwind's video.

And many thanks for posting. We look forward to your contributions as we search for a cure for this messy malady!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1630 on: 17/10/2008 19:26:40 »
...she prescribed me Levitra - which is why I felt obliged to register and post here today. On Levitra, I can confirm that the POIS symptoms were lessened dramatically post-orgasm. Even after an awesome load, I can still get up and do things. I don't feel paralyzed. However, I've never masturbated with Levitra and only used it for a short while until I was comfortable with my girlfriend - So my testing was limited.

This is a terrific confirmation to have a 2nd POIS sufferer reporting Levitra! Levitra has been my personal cure (50% to 75% alleviation of POIS symptoms) for about a year now. Glad to see that it can work safely for someone younger and not necessarily prescribed for ED!

Whoa, we're also exploring nitric oxide, which is an important component of the Levitra story. Related to that, Forum-member hurray has had success so far with an oxytocin-like substance. Oxytocin is manufactured at orgasm.
« Last Edit: 18/10/2008 04:38:22 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1631 on: 17/10/2008 19:34:57 »
IMPORTANT NOTICE TO ALL: Please see a physician if you wish to investigate Levitra, to see if it is right for you.
« Last Edit: 17/10/2008 19:55:28 by demografx »
 

Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1632 on: 18/10/2008 03:27:36 »
Fantastic post hurray on oxytocin and fenugreek. It was something I always wondered about from both a POIS and CFS aspect. There is a well known doctor who has success with some of his patients by giving them oxytocin, but it didnt seem that it worked for all his patients. When I enquired about it with my CFS doc he didnt seem to see the connection in regards to immunity + it was a hormone that had a clrear role for women but not really for men. I didn't push on it as it required regular (I think daily) IV injections. Something like oxcytocin would explain the differences in pois between the sexes. Also its role in social anxiety and appetite helps to support it case, and Chewbacca's post linking it to ED meds was great in helping to make the connection to Levitra.
I've read a couple of articles on it and I get conflicting info on fenugreek. Some say it mimics oxytocin and others say its synergestic and others say it stimulates the pituitary to produce more. Depending on how it works we could get variable results. I've started to trial it.

I've been thinking more on nitric oxide and I'm not so sure now. When I was younger I could hang a wet towel off my boner, and if I had an orgasm, the refactory period was under an hour and I was good to go again. To me this indicates a very healthy level of NO. If we were wiping out our NO levels then it would make sense that POIS would get worse as we get older and that does not seem to be the case.

Its annoying how many symptoms and circumstances are not quite the same for everyone. Some people get fever like effect, some people get diarrhea, neither of which I get. Then some people say ejeculation is a big deal and other say not (for me its not) and then some say an all out orgasm is worse and others say its better (I'm the latter).
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1633 on: 18/10/2008 04:54:26 »
Thanks, acronym. You have some interesting thoughts on Fenugreek and nitric oxide.

The connection between refractory period and NO?

I think we need more research and safely conducted trials.

Symptoms and circumstances are different, but I think the theme of 1) DAYS of postorgasmic symptoms, 2)fatigue and 3) mental fog is fairly consistent. I agree though, it would be nice if there weren't many variations.
 

Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1634 on: 18/10/2008 07:06:25 »
Whoa, I have noticed that anything that makes you sore has a recovery  period.  If I have an orgasm before the pain goes away that lengthens the time it to heal.  Perhaps the POIS recovery drains something necessary for healing.   
It seems exercising the day or even hours after may help the POIS effects process along, although no one seems to have the  desire to do much at all.  I wonder if anyone has noticed anything similar?   
 

Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1635 on: 18/10/2008 08:17:37 »
Here is a compilation I made.   I also have relevant questionnaire responses compiled, but to see these, you must fill out the questionnaire yourself.

Symptoms vary between sufferers, but there are many most of us have in common. 

Group 1 (Most Common Symptoms)
- brain fog
- intense withdrawal
- intense cravings
- difficulty communicating
- difficulty comprehending
- difficulty focusing
- thick-headed
- slow to respond
- absent mindedness
- short attention span (cannot concentrate for more than 2-3 minutes)
- anxiety
- poor short term memory
- lexical recall affected
- restless/agitated
- lack of creativity
- social phobia
- lack of confidence
- embarrassment
- mental exhaustion
Important notes: *  Symptoms generally last 6 to 70 hours.  Some do not recover as quickly during sleep as when they are awake. After 1-3 days of no orgasm, intense cravings for orgasm can re-appear, but the other symptoms do not re-surface unless stimulated by orgasm.  In a given month, people in this group are afflicted by symptoms between 10% and 90% of the time -- depending on the person, and frequency of orgasm.  Note: no loss of motor control apparent amongst most sufferers.  This is perhaps counter to the dopamine depletion theory.  Levitra has helped two sufferers with symptoms.  Oxytocin appears to be helping some people, and apparently Levitra has been linked with Oxytocin production.  Symptoms have sometimes immediately been alleviated by a subsequent orgasm.


Group 2 (Less common)
- derealisation
- lethargy (physical fatigue)
- cold (day 1), sweats/heat (day 2)
- dizziness
- paleness
- shame
- skin conditions following orgasm. (e.g. dry skin).
- visual disturbances
- lack of spontaneity
- diarrhea (helped by low IG diet)
- hypoglycemia (helpd by low IG diet)
- muscle tremors and spasms.
- depression
- headache
- skin conditions
- insomnia
- hunger and thirst affected

Group 3 (Even less common)
- dark circles beneath eyes
- curvature of spine
- joint pain
- dull pain in scalp
- elevated blood pressure  *(noticed by some members of groups 1 and 2)
- swollen neck glands
- double vision
- aphthous ulcers
- allergies
- mild fear of light
- swollen eyelids, runny nose, flu like symptoms
- dilated pupils
- burning fingertips

Also, very important compiled information:
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg95285#msg95285
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009
 

Offline Counterpoints

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1636 on: 18/10/2008 08:19:06 »
Note: I am currently very busy, and will only be available to post approximately once a week, for the next month.
 

Offline Whoa

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1637 on: 18/10/2008 09:11:38 »
Thanks for the greeting demografx. It is good to see an active thread on this topic.

To follow up my earlier post, my Rx for Levitra was 10mg. I had some left over, and tested one out today post-orgasm.

Basically, I woke up earlier than my girlfriend this morning and blasted one off. It was a bad idea(I get POIS symptoms worse if I don't go to sleep immediately after orgasm) and I've had horrible POIS symptoms all day. I just wanted to lay down by myself and read or nap, but I couldn't because there was too much to do, and my girlfriend suggested that later in the evening we'd have sexual intercourse.

So I decided to try taking a Levitra midday to see if it would take away the symptoms. It did not. Perhaps because it is now slightly expired, or because it should be taken before ejaculating. I'll try the latter before my next explosive solo session and see what happens.

 

Offline hurray

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1638 on: 18/10/2008 12:04:59 »
Thanks for all the great posts!

I only have a couple of minutes before I go away for a few days, just wanted to say that I have been taking 3 capsules 3 times a day,I am taking Solgar Fenugreek containing 370mg raw fenugreek seed powder and 150mg Fenugreek seed powdered extract.

Thanks again for the support!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1639 on: 18/10/2008 20:40:49 »

Here is a compilation I made...


COUNTERPOINTS:

BRILLIANT!

THANK YOU!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1640 on: 18/10/2008 22:45:49 »
Thanks for the greeting demografx. It is good to see an active thread on this topic.

To follow up my earlier post, my Rx for Levitra was 10mg. I had some left over, and tested one out today post-orgasm.

Basically, I woke up earlier than my girlfriend this morning and blasted one off. It was a bad idea(I get POIS symptoms worse if I don't go to sleep immediately after orgasm) and I've had horrible POIS symptoms all day. I just wanted to lay down by myself and read or nap, but I couldn't because there was too much to do, and my girlfriend suggested that later in the evening we'd have sexual intercourse.

So I decided to try taking a Levitra midday to see if it would take away the symptoms. It did not. Perhaps because it is now slightly expired, or because it should be taken before ejaculating. I'll try the latter before my next explosive solo session and see what happens.


Thanks, Whoa. I tried Levitra once or twice _AFTER_wards (but shortly thereafter), and it worked! I was surprised.

It worked, but it did not work as powerfully as taking it _before_hand.

I reported on it here when it happened.
 

Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1641 on: 19/10/2008 00:28:23 »
I bought some Fenugreek seed last night, twice today I took a single 620mg capsule. This stuff definitely has an effect on my brain, it kinda feels like I'm on an antidepressant or something, although I have to give it some time to see if it is good for me or not. I didn't expect this reaction, I think I'll ease down to one a day. I have not recently experienced orgasm to know if there is any POIS altering effect.

Sparking my curiosity in herbs I did a little searching...has anyone heard of Brahmi (Bacopa)?

Quote
Brahmi has been valued as a cardiac, nerve and brain tonic and widely used by students for improving mental clarity, confidence, intelligence, concentration and memory recall. Brahmi as herbal supplements and tablets have been marketed for super learning, for memory and as a brain tonic. In 1963 research on the brahmi plant identified 2 active molecules: Bacoside A that assists in the release of nitric oxide allowing relaxation of the aorta and veins and blood to flow more smoothly through the body and aids circulation; and Bacoside B, a protein valued for nourishing nerve cells in the brain.
http://myfolia.com/plantings/25

I also sampled some Stevia today, a herbal sweetener, it wasn't too bad on oatmeal, (although I eventually added some maple syrup.  :))
 

Offline Chewbacca

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1642 on: 19/10/2008 01:33:21 »
A quick note about levitra and oxytocin for those who are taking it as a treatment for POIS. The increase in oxytocin only happens during sexual stimulation. Not sure why this is, but that's what the article I read said that linked oxytocin increase to PDE-5 inhibitors(levitra, viagra, cialis). If an increase in oxytocin is what is responsible for lessening the effects of POIS... if you take PDE-5 inhibitors after orgasm you will not get an increase in the levels of oxytocin!!! This is probably why demografx and whoa had more sever symtoms when they took levitra after orgasm....because the mediating effects of PDE-5 inhibitors only work when you take the pill before sexual stimulation. If you don't, you don't get an increase in oxytocin.

So just remember....take the pill first...then do the deed!!!! - and as always, make sure you have a doctors approval(disclaimer:)
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1643 on: 19/10/2008 01:38:01 »
IMPORTANT NOTICE TO ALL:
Rx, FENUGREEK, AND ALL OTHER NON-PRESCRIPTION SUPPLEMENTS


I would strongly urge a healthcare practitioner or physician's involvement before taking any prescription drugs OR health supplements mentioned here. For example, googling Fenugreek shows that it is used to enlarge female breasts! HOWEVER, we are not physicians or healthcare practitioners here. Please use caution when following someone else's suggestions, no matter how enticing. Everyone's body chemistry is unique.
« Last Edit: 19/10/2008 03:50:09 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1644 on: 19/10/2008 03:51:32 »
A quick note about levitra and oxytocin for those who are taking it as a treatment for POIS. The increase in oxytocin only happens during sexual stimulation. Not sure why this is, but that's what the article I read said that linked oxytocin increase to PDE-5 inhibitors(levitra, viagra, cialis). If an increase in oxytocin is what is responsible for lessening the effects of POIS... if you take PDE-5 inhibitors after orgasm you will not get an increase in the levels of oxytocin!!! This is probably why demografx and whoa had more sever symtoms when they took levitra after orgasm....because the mediating effects of PDE-5 inhibitors only work when you take the pill before sexual stimulation. If you don't, you don't get an increase in oxytocin.

So just remember....take the pill first...then do the deed!!!! - and as always, make sure you have a doctors approval(disclaimer:)

Chewbacca, very good post. Thanks.
 

Offline tarkington

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1645 on: 19/10/2008 16:14:52 »
Great News!!!!!!!!

I bought Relora from Swanson Health for a good price (only $7.00).  I then took three capsules per day.  But first let me say that before I started taking Relora I had not had an orgasm for at least two weeks, so I was pretty normal.  I also had started taking Centrum Chewable tablets once a day for about two weeks.  So after taking Relora three times a day for four days I decided to have an orgasm.  I felt just fine and normal.  I encountered no feeling inside me like many people describe feeling after orgasm.  But I did start to feel the onset of my POIS symptoms after about four hours.  BUT, they were reduced to about 10 - 15% of their normal power (instead of feeling terrible -- 9 out of 10 on scale -- I felt around 2).  I was still feeling pretty normal.  And to make things better, these reduced symptoms only lasted for about 4 or 5 hours.  That is so much better than my normal 72 hours.  So to summarize, Relora reduced all of my symptoms to virtually nothing.  I have now had two orgasms both or which followed the same pattern.  I believe this is as close as I can get to a "cure." 

By the way my symptoms included feeling brain fog, anti social, helpless, depressed, confused, anxiety.  I had no physical problems like dry skin or pain (well I did have cold sweats for about 5 hours following orgasm).  all these went away. 

Also, when I first started taking Relora I felt much calmer and less stressed.  I have always been stressed and anxious and this helped.
I HOPE THIS CONTINUES TO WORK THIS WAY!!
 

Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1646 on: 19/10/2008 20:49:16 »
Well I didn't wake up with female breasts this morning, this is good. :D Last night I had an NE (it seemed somewhat small), and today I had zero POIS effects. I am still consuming raw garlic so I can't say if fenugreek is responsible or not, but I am hopful that it turns out to be of assistance.

Good stuff Tarkington, nice to hear you had some positive results. When I tried Relora I was very sensitive to it. It aggrivated my insomnia so I gave up on it.

 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1647 on: 20/10/2008 16:00:40 »
TARKINGTON:

THANKS FOR POSTING

YOUR GREAT NEWS!!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1648 on: 20/10/2008 16:02:43 »
JOHN,

Congratulations on maintaining breast size!


;D
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1649 on: 20/10/2008 22:55:40 »
Last night I had an NE (it seemed somewhat small), and today I had zero POIS effects. I am still consuming raw garlic so I can't say if fenugreek is responsible or not, but I am hopful that it turns out to be of assistance.

John, if you never "escaped" POIS in the past with "small NE" this would be a good sign! (I never escaped it [:-'(]  <<real tears).

Please tell us!
« Last Edit: 21/10/2008 00:06:19 by demografx »
 

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #1649 on: 20/10/2008 22:55:40 »

 

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