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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6449144 times)

Offline Coreman

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17375 on: 02/12/2012 16:16:47 »
HI, Im back after 24 days of BROMOCRIPTINE treatment.

PRANCER was right: it's too early to break out the champagne...

I am getting a little better, but not to the level I expected.


MY AGENDA:
Firstly, I'm seeing the specialist in 2 days who may prescribe CLOMIFENE CITRATE this time.

"CLOMIFENE CITRATE has been found very effective in the treatment of secondary male hypogonadism in many cases.[3] This has shown to be a much more attractive option than testosterone replacement therapy (TRT)" -  Wikipedia.


Secondly, I'm waiting for an MRI test to face the fact if  I  have
a PROLACTINOMA tumor. (A prolactinoma is a noncancerous pituitary tumor that produces a hormone called prolactin)

I'll  report back on the result of the MRI test and progress!

Cheers,

COREMAN.




Citation:
-----------------------

That sounds like some pretty good news Coreman. Although it's early, I'm already getting excited! Please keep us up to date on any new developments. Thanks a lot and good luck!
 - Prancer

PS: Let's give it the 2-week rule that B_Daniel suggested (wait couple weeks and see if you are still cured or feeling much better) before we really break out the champagne!

-------------------------
You're right, Prancer. Thanks! I'll give it a 2 weeks' go!
Coreman.

-------------------------
Dear Demografx and Others!
Iíve been having a BREAKTHROUGH  !!!
(Me: a member for 5 years, suffering from POIS for 10 years.)

To put it short, Iím diagnosed with Hyperprolactinaemia, taking pills and getting way better!  :)
http://en.wikipedia.org/wiki/Hyperprolactinaemia [nofollow]

The results of my lab tests:
(performed after a release):
Total Testo: 4,2 seriously under the range of 8,6 Ė 26
Prolactine:   1646 (!!) seriously over the range of 86-324

Taking Bromocriptine for 5 days, and feeling much better !!! :)

I met an Endocrinologist with profound knowledge.
->an adenoma tumour (so called prolactinoma) is suspected.
-> I am enlisted for an MRI test to check whether I really have prolactinoma.
Cheers!! Iím over the moon now! :)

Coreman."
----------------------------
« Last Edit: 02/12/2012 16:18:34 by Coreman »
 

Offline Ninjagasm

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17376 on: 02/12/2012 18:19:54 »
I'm a new user so I apologize if somebody said this already...
Okay so I used to expierence severe to mild brain fog and intense fatigue everytime I orgasmed. I started taking a Vitamin B-100 Complex 100mg for the fatigue before I orgasmed and two tablets of Lecithin 120 mg for the brain fog before and after orgasm. Been "cured" ever since. Once again we are all different and react to different medication/supplements. Hope this helped :)
« Last Edit: 02/12/2012 18:26:23 by Ninjagasm »
 

Offline Ninjagasm

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17377 on: 02/12/2012 18:23:13 »
Oh and I'm pretty sure the key is to have a orgasm atleast 3-5 times a week or your body will never get used to the POIS. I used to be scared to orgasm because of the symptoms so I would only have one once a week. Its only been 3 days but so far so good.
 

Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17378 on: 02/12/2012 21:59:36 »
I'm a new user so I apologize if somebody said this already...
Okay so I used to expierence severe to mild brain fog and intense fatigue everytime I orgasmed. I started taking a Vitamin B-100 Complex 100mg for the fatigue before I orgasmed and two tablets of Lecithin 120 mg for the brain fog before and after orgasm. Been "cured" ever since. Once again we are all different and react to different medication/supplements. Hope this helped :)

Welcome ninjagasm, and thank you for sharing what's helped you! I'm happy to hear you are feeling better. :)

I bought a lecithin supplement after hearing your success story. You're right that we're all different so I'm not getting overly excited, but I'm still highly optimistic with every new supplement I try. (By the way, I now officially have amassed A LOT of different supplements. Those that don't know I have pois think that I've become a dr. oz aficionado.) I don't mind experimenting with new supplements because one day I might try the perfect one!

On another matter, for those that get pois or feel worse after a hot shower, I think I found something that helps me and might help you too. Basically I just switched my hair dryer from one that uses mainly HEAT with little air flow to dry hair to one that uses a lot of air flow and not as much heat. I have found that this has helped not only to save time by drying my hair faster, but also to eliminate most of the symptoms I felt. In my case, it might have actually been the heat from the hair dryer against my scalp that was causing most of the symptoms. So yeah, just wanted to throw that out in case someone was having a similar problem. K, bye for now!
 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17379 on: 02/12/2012 22:17:50 »
Peopple with urticaria sometimes use a hot shower to release histamine. It feels better after a while. It all depends on the length of the shower.
See http://en.wikipedia.org/wiki/Urticaria

and more specifically http://en.wikipedia.org/wiki/Cholinergic_urticaria
I think POIS is similar to this but without the hives. I've had some rosacea but my body certainly doesn't become covered in hives. Anyway, the connection between the 2 is mast cell release of histamine etc.
 

Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17380 on: 04/12/2012 16:33:50 »
Just an update,

Its been after one month and one week after starting Calcium channel blocker. 

Now my intensity and frequency of the pois is reduced by great extent.  I can say approximately 60 to 70% of intensity of my POIS is reduced. 

Another interesting fact from my last 3 weeks is I will get symptoms now when I have orgasm.  I had even tried daily 4 o .  But no symtoms.  But if in case I go to bed at late night say 12 or 1, POIS symoms back but,intensity of pois is very low and will be cured in just 2 days. 
 

Offline Habibou

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17381 on: 04/12/2012 21:20:36 »
that s great it is working for you for the moment Nathan !
Do you know if the 150 patients of PCH or POIS got totally cured with the flunarizine dihydrochloride?

I will start the same treatment in 3 days for over 3 months, under the supervisiory control of my GP.
 

Offline Ninjagasm

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17382 on: 05/12/2012 00:36:32 »
that s great it is working for you for the moment Nathan !
Do you know if the 150 patients of PCH or POIS got totally cured with the flunarizine dihydrochloride?

I will start the same treatment in 3 days for over 3 months, under the supervisiory control of my GP.

I apologize for being a lazy bastard, but can you guys please summarize exactly what this calcium supplement or what ever it is your talking about???? Thank youuuu!
 

Offline Ninjagasm

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17383 on: 05/12/2012 00:39:02 »
and whats the logic behind using it??
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17384 on: 05/12/2012 06:36:13 »
I have a confusion about whether I have POIS or Post Coital headche and for my condition doctor told that it is a Post Coital headche illness.  So, please explain me whether my problem is a POIS by seeing the following symtoms.  By Calcium Channel blocker, my POIS has clearing now, so I want to discuss with doctor on POIS vs Post Coital headche illness. 

When I am in POIS, I have the following symtoms,

a) Brain fog, low concentration, low memory, Fatigue, burning in head, confusion
b) Depression
c) Burning eyes,
d) feeling imbalance in head
e) Abnormal breathing
f) High Anxiery
g) Difficult to have eye contact
h) Stammerting at the great extent
i) Imbalance in sleep and excessive dreaming
j) Emotional imbalance
h) Very rare occasion I also had throat infection.
and I don't get any flu and physical symtoms.
These symtoms will be there for atleast one months and very difficult to remove when attacked.  Upto last 2 months, my symtoms as explained above.  Please clarifiy to me.

you have pois. Do you even get any headaches after orgasm.
you can crosscheck your symptoms with dr waldingers symptoms list and you will see your symptoms match alot of the symptoms.
 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17385 on: 05/12/2012 09:32:16 »
and whats the logic behind using it??

Pretty much the exact opposite of a calcium supplement. Indeed, I think some people have gotten confused and started taking extra calcium which would make things worse. 
Calcium channel blockers are described here
http://en.wikipedia.org/wiki/Calcium_channel_blocker
They are used to reduce blood pressure, prevent epileptic seizures or to reduce frequency or severity of migraines. I don't know whether they're safe to use long term but the argument is that POIS symptoms (and this sounds reasonable to me) are actually similar to post coital headache.

Nathan is using this http://en.wikipedia.org/wiki/Flunarizine
Which is both an anti-histamine and a cerebrovascular dilator, i.e. it relaxes blood vessels in your brain See http://dpic.org/sites/default/files/pdf/DIR_CCBs.pdf
 

Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17386 on: 06/12/2012 05:00:19 »
fyi: I've been using DAOsin for a couple weeks and it hasn't helped my digestion issues at all.
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17387 on: 06/12/2012 06:54:13 »
Kurtosis, can you take claritin-D and still fall asleep after?  I know you mentioned the pseudoephedrine as a stimulant.  I guess I haven't tried that either, I tried the claritin 24 hour, and like Prancer said you sometimes feel it the next day.  Do you get the same reaction of feeling POIS the next day?



And... on a last note... Does anybody experience sleeping problems like I do?  I would like to know if it is related to POIS or not, or maybe it's just me being anxious because of this condition.

I have had insomnia for many years, maybe around 12 years now. It is sleep maintenance insomnia where I wake in the middle of the night and sometimes have difficulty getting back to sleep. Stress is a definite contributor, if not the sole reason. What form of insomnia do you have GC?

Usually when I sleep, it's like I cannot "relax", sort of my brain doesn't shut off, and I can't get into the mood of calmness/relaxation.  Sometimes I'll wake up in the middle of the night sweating and nervous, so it almost seems like a symptom of anxiety, but I don't know if POIS is the cause or something else.

But recently I've been sleeping well just by taking vitamin C in the morning (Ester C), I think its reaction with histamine is causing me to sleep better throughout the night even though I take it in the morning.
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17388 on: 06/12/2012 06:55:35 »
I'm a new user so I apologize if somebody said this already...
Okay so I used to expierence severe to mild brain fog and intense fatigue everytime I orgasmed. I started taking a Vitamin B-100 Complex 100mg for the fatigue before I orgasmed and two tablets of Lecithin 120 mg for the brain fog before and after orgasm. Been "cured" ever since. Once again we are all different and react to different medication/supplements. Hope this helped :)

Do you have any other symptoms besides brain fog?
 

Offline Ninjagasm

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17389 on: 07/12/2012 05:39:39 »

Do you have any other symptoms besides brain fog?
[/quote]

Intense fatigue, headache, very irritable, mentally unstable in general, insomnia, feeling of intense heat, my pain tolerance goes down, if i go to the gym the amount of weight I can lift goes down about 25 pounds, anxiety
 

Offline Kingkong

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17390 on: 07/12/2012 23:33:30 »
Hi everybody, I have good news. I've tried flunarizine (sibelium) as Nathan. I'M taking 10 mg each days since november 19th. On december 5th I had an O for the first time since two month. I had a normal night of 8 hours. The nightmares were very light. When I wook up the 6th, it was difficult but not as usually when I'm having an O. I was tired the 6th at work. I`m working in an office. Yesterday the 6th, I had a second O. I went to bed at 20 o'clock because I was very tired and I wake up at 6 this morning. So I sleep 10 hour last night. I would say that all my symptoms were gone by 10 o'clock this morning. Yesterday, I could felt a physical fatigue but about 50% mental fatigue that I have usually. Yesterday, I could felt my ganglion a bit but today absolutly nothing. IT's a lot more efficient than NIACIN. Today I had no irritability at all and no mental problem. It's a very big succes for me. I'M must say that the first 10 day that I began to take Sibelium, I was sleeping 10 hour a day and I was tired. But now it's OK. My doctor told me that by 8 weeks of taking Sibelium, I will be very hungry and could take 10-20 pounds. I will have to control myself not to eat too much. I'm continuing to take flunarizine and I 'll give more news later. I'm 53 yers old and I never felt good like that since 14 year the after I had an O. As I wrote on november 20th on this site, I'm taking citalopram for many years. Maybe i't for that reason that I was so tired de first 10 days of taking flunarizine.
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17391 on: 08/12/2012 02:29:58 »
Hi everybody, I have good news. I've tried flunarizine (sibelium) as Nathan. I'M taking 10 mg each days since november 19th. On december 5th I had an O for the first time since two month. I had a normal night of 8 hours. The nightmares were very light. When I wook up the 6th, it was difficult but not as usually when I'm having an O. I was tired the 6th at work. I`m working in an office. Yesterday the 6th, I had a second O. I went to bed at 20 o'clock because I was very tired and I wake up at 6 this morning. So I sleep 10 hour last night. I would say that all my symptoms were gone by 10 o'clock this morning. Yesterday, I could felt a physical fatigue but about 50% mental fatigue that I have usually. Yesterday, I could felt my ganglion a bit but today absolutly nothing. IT's a lot more efficient than NIACIN. Today I had no irritability at all and no mental problem. It's a very big succes for me. I'M must say that the first 10 day that I began to take Sibelium, I was sleeping 10 hour a day and I was tired. But now it's OK. My doctor told me that by 8 weeks of taking Sibelium, I will be very hungry and could take 10-20 pounds. I will have to control myself not to eat too much. I'm continuing to take flunarizine and I 'll give more news later. I'm 53 yers old and I never felt good like that since 14 year the after I had an O. As I wrote on november 20th on this site, I'm taking citalopram for many years. Maybe i't for that reason that I was so tired de first 10 days of taking flunarizine.

I looked it up and that is one of the side effects of sibelium.
Also do you have any physical symptoms like fatigue,and fluelike symptoms.

Not saying this because of flunarizine success with some. But my first true O with another person produce the most most worst worst headache ever. I dont know how to explain it " the pain level felt like i busted a vein in my head and that pain lasted all day i couldnt get out of bed."
The only problem is, it only happened that time and never since.  And i did not notice any pois symptoms untill about three months from that day.
« Last Edit: 08/12/2012 07:14:10 by CertainlyPOIS »
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17392 on: 08/12/2012 03:00:49 »
according to this it looks like calcium channel blocker act differently in the body.
And Flunarizine and nimodipine are the only ones who pretty much just affect the brain.
http://dpic.org/sites/default/files/pdf/DIR_CCBs.pdf

if you trying this you should probabbly stick to just flunarizine.
 

Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17393 on: 08/12/2012 10:02:04 »
Pseudoephedrine is a stimulant which encourages the body to produce adrenaline / epinephrine. This reduces the level of histamine, similar to the way getting an epi-pen injection counteracts a severe allergic reaction.
You're basically shocking your system out of the POIS state. Yeah, it works but, as I said, I can't see this being a long term solution but it does feel a lot better than POIS :)

Reallly good point Kurtosis! For the last month, it's become increasingly obvious to me that POIS is, at its heart, a histamine problem. As confirmation of this, ive found that foods high in histamine make me feel worse, and supplements that break down histamine, like Sam-E, make me feel a lot better!!

The only part of this theory that was still bugging me though was understanding why caffeine and ritilin make me feel better. What does that have to do with too much histamine? 

As u so precisely explain above, adrenaline clears histamine instantly, giving us relief. And then as u also wrote in another post, this explains why we get worn out so easily, mentally and physically. All day every day we have a high level of adrenaline in order to fight the high histamine.  Consequently, we have adrenal fatigue from using too much adrenaline all the time!  it makes so much sense!

I found a website a guy wrote about his problems breaking down histamine. Youll see how eerily familiar it sounds to pois.  It also explores this link with adrenaline (also know  as epinephrine).

Clip from guy's blog:
Adrenaline (Epinephrine) is the only chemical that can quickly eliminate histamine in a person. So called "antihistamines" like Benadryl only work to block some of your body's histamine receptors relieving some histamine related symptoms, they do not remove histamine. If you do go into anaphylactic shock where your organs essentially shut down, it is essential that you are injected with adrenaline immediately to counteract the dangerously high histamine level and prevent death. My histamine level was very high but not dangerous. My body tried in vain to reduce this high level of histamine to a normal level, by releasing abnormally large quantities of adrenaline into my blood stream. This created nervous energy and sometimes even panic attacks if the spikes were large enough. The body normally has a certain amount of adrenaline that increases and decreases slightly to balance your body's histamine level. In its attempt to reduce my histamine level, my body would essentially use up all my adrenaline (as shown by my blood test). This would leave me feeling anywhere from moderately tired to frighteningly exhausted. Its probably difficult to imagine being so drained of energy that it would actually scare you, but it happened to me frequently. My high histamine level also caused my Meniere's like symptoms, as well as difficulty thinking, focusing, and remembering things.
« Last Edit: 08/12/2012 10:32:37 by B_Daniel »
 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17394 on: 08/12/2012 11:37:32 »
Quote
This would leave me feeling anywhere from moderately tired to frighteningly exhausted. Its probably difficult to imagine being so drained of energy that it would actually scare you, but it happened to me frequently

And epinephrine is made from norepinephrine and that's made from dopamine so the effort reduces available dopamine, possibly leading to lower metabolites of dopamine in the urine (e.g. DOPAC).

That's what I think anyway but I'm going to hold out until I see the genetic tests before making a decision about how best to deal with this. If there's no obvious methylation problem that could be affecting breakdown of histamine then possibilities include too many mast cells or mast cell instability (so a mast cell stabiliser may be the answer) or another possibility is, genuinely, a parasitic infection of some sort which may lead to increased histamine levels, impaired digestion and other problems that could account for POIS.
 

Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17395 on: 08/12/2012 17:24:27 »
If someone were to use an epinephrine auto injector (like EpiPen), would this instantly clear his pois symptoms? I'm just wondering & not recommending that anyone try this by the way.
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17396 on: 08/12/2012 18:37:59 »
If someone were to use an epinephrine auto injector (like EpiPen), would this instantly clear his pois symptoms? I'm just wondering & not recommending that anyone try this by the way.

Counterpoint tried this and it didnt work for him.
 

Offline Kingkong

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17397 on: 08/12/2012 19:58:00 »
Hi everybody, I have good news. I've tried flunarizine (sibelium) as Nathan. I'M taking 10 mg each days since november 19th. On december 5th I had an O for the first time since two month. I had a normal night of 8 hours. The nightmares were very light. When I wook up the 6th, it was difficult but not as usually when I'm having an O. I was tired the 6th at work. I`m working in an office. Yesterday the 6th, I had a second O. I went to bed at 20 o'clock because I was very tired and I wake up at 6 this morning. So I sleep 10 hour last night. I would say that all my symptoms were gone by 10 o'clock this morning. Yesterday, I could felt a physical fatigue but about 50% mental fatigue that I have usually. Yesterday, I could felt my ganglion a bit but today absolutly nothing. IT's a lot more efficient than NIACIN. Today I had no irritability at all and no mental problem. It's a very big succes for me. I'M must say that the first 10 day that I began to take Sibelium, I was sleeping 10 hour a day and I was tired. But now it's OK. My doctor told me that by 8 weeks of taking Sibelium, I will be very hungry and could take 10-20 pounds. I will have to control myself not to eat too much. I'm continuing to take flunarizine and I 'll give more news later. I'm 53 yers old and I never felt good like that since 14 year the after I had an O. As I wrote on november 20th on this site, I'm taking citalopram for many years. Maybe i't for that reason that I was so tired de first 10 days of taking flunarizine.

I looked it up and that is one of the side effects of sibelium.
Also do you have any physical symptoms like fatigue,and fluelike symptoms.

Not saying this because of flunarizine success with some. But my first true O with another person produce the most most worst worst headache ever. I dont know how to explain it " the pain level felt like i busted a vein in my head and that pain lasted all day i couldnt get out of bed."
The only problem is, it only happened that time and never since.  And i did not notice any pois symptoms untill about three months from that day.

Yes I was very tired the first 10 day that I took Sibelium. But gradualy, the fatigue and the fluelike symptom's diseapar. Flunarizine takes two months to reach full efficient. I'm trusting my doctor when he told me that was no contraindication to take this drugs. He his 64 years old and he prescribed flunarizine a lot for headache in the past. For him is a good drug even because he had no problem in the past whit his patient taking flunarizine.
 

Offline Kingkong

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17398 on: 08/12/2012 20:24:01 »
i took claritin-d 3 times already, and every time it worked.
I've tried claritin during two week two month ago and I had no benifit using that. It gave me ligh headache only.
 

Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17399 on: 08/12/2012 22:01:49 »
If someone were to use an epinephrine auto injector (like EpiPen), would this instantly clear his pois symptoms? I'm just wondering & not recommending that anyone try this by the way.

Counterpoint tried this and it didnt work for him.

Did he?  Certainly, will you share with us the quote from the forum where he says he tried it??  I searched the forum for Epipen and saw Counterpoints say that he owned one, but didn't see him say that he had ever used it.  Unfortunately we can't ask him because somebody banned him.

I've never used an epipen, and they're dangerous to try when not absolutely necessary so don't be a hero, but I'm fairly confident we'd feel instantly better.  Anyone else have experience with an epipen??
« Last Edit: 08/12/2012 22:29:38 by B_Daniel »
 

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Re: Post Orgasmic Illness Syndrome (POIS)
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