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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6461983 times)

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17400 on: 09/12/2012 01:00:39 »
How does the peanut alergy feel relative to POIS symptoms?

I have a severe (life threatening) allergy to peanuts, and it feels nothing like POIS.  The treatment (a shot of adrenaline) does not seem to have an effect on POIS symptoms.  (If it does it probably helps a little, but there isn't enough evidence for me to say).

However, this does not discredit Waldinger's hypothesis.  Auto-immune reactions (e.g. lupus) can be quite different from normal allergic reactions.

This is one of the places he said he tried ephipnephrine.
 

Offline B_Daniel

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17401 on: 09/12/2012 01:56:10 »
How does the peanut alergy feel relative to POIS symptoms?

I have a severe (life threatening) allergy to peanuts, and it feels nothing like POIS.  The treatment (a shot of adrenaline) does not seem to have an effect on POIS symptoms.  (If it does it probably helps a little, but there isn't enough evidence for me to say).

However, this does not discredit Waldinger's hypothesis.  Auto-immune reactions (e.g. lupus) can be quite different from normal allergic reactions.

This is one of the places he said he tried ephipnephrine.

Not to completely discount his statement but keep in mind this is A) only 1 data point, and B) When he's used the epipen, he's also suffering from anaphylactic shock from his peanut allergy, which i'd imagine would obscure his view of the results.

 
« Last Edit: 09/12/2012 02:03:47 by B_Daniel »
 

Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17402 on: 09/12/2012 03:21:10 »
I'm interested in it because if a POISer does actually try this one day under close doctor supervision, and if it significantly reduces or eliminates their symptoms, then that would pretty much seal the deal (for me at least) about the histamine theory. But yeah, one should never try this alone because it can be very dangerous if not done correctly.

I really don't see why it shouldn't work because "epinephrine is the only chemical that can quickly eliminate histamine in a person. Antihistamines only work to block some of your body's histamine receptors (relieving some histamine related symptoms), they do not remove histamine."
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17403 on: 09/12/2012 04:06:32 »
Pseudoephedrine is a stimulant which encourages the body to produce adrenaline / epinephrine. This reduces the level of histamine, similar to the way getting an epi-pen injection counteracts a severe allergic reaction.
You're basically shocking your system out of the POIS state. Yeah, it works but, as I said, I can't see this being a long term solution but it does feel a lot better than POIS :)

Reallly good point Kurtosis! For the last month, it's become increasingly obvious to me that POIS is, at its heart, a histamine problem. As confirmation of this, ive found that foods high in histamine make me feel worse, and supplements that break down histamine, like Sam-E, make me feel a lot better!!

The only part of this theory that was still bugging me though was understanding why caffeine and ritilin make me feel better. What does that have to do with too much histamine? 

As u so precisely explain above, adrenaline clears histamine instantly, giving us relief. And then as u also wrote in another post, this explains why we get worn out so easily, mentally and physically. All day every day we have a high level of adrenaline in order to fight the high histamine.  Consequently, we have adrenal fatigue from using too much adrenaline all the time!  it makes so much sense!

I found a website a guy wrote about his problems breaking down histamine. Youll see how eerily familiar it sounds to pois.  It also explores this link with adrenaline (also know  as epinephrine).

Clip from guy's blog:
Adrenaline (Epinephrine) is the only chemical that can quickly eliminate histamine in a person. So called "antihistamines" like Benadryl only work to block some of your body's histamine receptors relieving some histamine related symptoms, they do not remove histamine. If you do go into anaphylactic shock where your organs essentially shut down, it is essential that you are injected with adrenaline immediately to counteract the dangerously high histamine level and prevent death. My histamine level was very high but not dangerous. My body tried in vain to reduce this high level of histamine to a normal level, by releasing abnormally large quantities of adrenaline into my blood stream. This created nervous energy and sometimes even panic attacks if the spikes were large enough. The body normally has a certain amount of adrenaline that increases and decreases slightly to balance your body's histamine level. In its attempt to reduce my histamine level, my body would essentially use up all my adrenaline (as shown by my blood test). This would leave me feeling anywhere from moderately tired to frighteningly exhausted. Its probably difficult to imagine being so drained of energy that it would actually scare you, but it happened to me frequently. My high histamine level also caused my Meniere's like symptoms, as well as difficulty thinking, focusing, and remembering things.

It does seem related to histamine, I find that taking 500 mg of vitamin c every day relieves me from most of the symptoms.
 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17404 on: 09/12/2012 13:11:30 »
Pseudoephedrine is a stimulant which encourages the body to produce adrenaline / epinephrine. This reduces the level of histamine, similar to the way getting an epi-pen injection counteracts a severe allergic reaction.
You're basically shocking your system out of the POIS state. Yeah, it works but, as I said, I can't see this being a long term solution but it does feel a lot better than POIS :)

Reallly good point Kurtosis! For the last month, it's become increasingly obvious to me that POIS is, at its heart, a histamine problem. As confirmation of this, ive found that foods high in histamine make me feel worse, and supplements that break down histamine, like Sam-E, make me feel a lot better!!

The only part of this theory that was still bugging me though was understanding why caffeine and ritilin make me feel better. What does that have to do with too much histamine? 

As u so precisely explain above, adrenaline clears histamine instantly, giving us relief. And then as u also wrote in another post, this explains why we get worn out so easily, mentally and physically. All day every day we have a high level of adrenaline in order to fight the high histamine.  Consequently, we have adrenal fatigue from using too much adrenaline all the time!  it makes so much sense!

I found a website a guy wrote about his problems breaking down histamine. Youll see how eerily familiar it sounds to pois.  It also explores this link with adrenaline (also know  as epinephrine).

Clip from guy's blog:
Adrenaline (Epinephrine) is the only chemical that can quickly eliminate histamine in a person. So called "antihistamines" like Benadryl only work to block some of your body's histamine receptors relieving some histamine related symptoms, they do not remove histamine. If you do go into anaphylactic shock where your organs essentially shut down, it is essential that you are injected with adrenaline immediately to counteract the dangerously high histamine level and prevent death. My histamine level was very high but not dangerous. My body tried in vain to reduce this high level of histamine to a normal level, by releasing abnormally large quantities of adrenaline into my blood stream. This created nervous energy and sometimes even panic attacks if the spikes were large enough. The body normally has a certain amount of adrenaline that increases and decreases slightly to balance your body's histamine level. In its attempt to reduce my histamine level, my body would essentially use up all my adrenaline (as shown by my blood test). This would leave me feeling anywhere from moderately tired to frighteningly exhausted. Its probably difficult to imagine being so drained of energy that it would actually scare you, but it happened to me frequently. My high histamine level also caused my Meniere's like symptoms, as well as difficulty thinking, focusing, and remembering things.

It does seem related to histamine, I find that taking 500 mg of vitamin c every day relieves me from most of the symptoms.
That's great to hear GC.
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17405 on: 10/12/2012 22:51:19 »
i took claritin-d 3 times already, and every time it worked.
I've tried claritin during two week two month ago and I had no benifit using that. It gave me ligh headache only.

I've realized that claritin either works or it doesn't, hit or miss.  The last time I took it, it barely did anything after 3 0's.  What I remember helping me out of the antihistamines was 2 tablets of benadryl instead of one.  Even though it might make me tired the following day, it's better than having POIS symptoms.  I will try two tablets of benadryl this friday.
 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17406 on: 11/12/2012 10:09:48 »
i took claritin-d 3 times already, and every time it worked.
I've tried claritin during two week two month ago and I had no benifit using that. It gave me ligh headache only.

I've realized that claritin either works or it doesn't, hit or miss.  The last time I took it, it barely did anything after 3 0's.  What I remember helping me out of the antihistamines was 2 tablets of benadryl instead of one.  Even though it might make me tired the following day, it's better than having POIS symptoms.  I will try two tablets of benadryl this friday.

The benefit from clarityn is probably from the pseudoephedrine product (clarityn D). There's limited anti-histamine effect in the brain from the standard clarityn, it's designed that way so it doesn't make you drowsy. Benadryl on the other hand does make you drowsy but is probably more effective. They often talk about using it on mastocytosis and urticaria forums.
 

Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17407 on: 11/12/2012 15:01:21 »
Just an update.  Its after one month and two weeks after taking calcium channel blocker i.e. fluneraize. Most of the POIS symptoms has been reduced.  Yesterday consulted my doctor and he prescibed another two months continue for this.  POIS symtoms relieved greatly by this medicine.  Hoping for the best. Pl try this with advice of GP.  It takes app one month to give correct results.
but one drawback of this medicine is it increases weight. 
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17408 on: 11/12/2012 16:46:35 »
Just an update.  Its after one month and two weeks after taking calcium channel blocker i.e. fluneraize. Most of the POIS symptoms has been reduced.  Yesterday consulted my doctor and he prescibed another two months continue for this.  POIS symtoms relieved greatly by this medicine.  Hoping for the best. Pl try this with advice of GP.  It takes app one month to give correct results.
but one drawback of this medicine is it increases weight. 


my solution to that is to weightlift it will turn all that food into muscles.
get sexy while fixing my brain. Win win( hopefully am not to tired.)

 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17409 on: 11/12/2012 16:48:54 »
I went to my doctor for flunarizine. While he researches flunarizine he presribed intutiv(guafacine),It supposedly works on concentration and other cognitive problems. It is suppose to work pretty quickly so i will let you guys know how it works.
any body tried intutiv
 
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17410 on: 11/12/2012 17:47:00 »
If someone were to use an epinephrine auto injector (like EpiPen), would this instantly clear his pois symptoms? I'm just wondering & not recommending that anyone try this by the way.

Counterpoint tried this and it didnt work for him.

Did he?  Certainly, will you share with us the quote from the forum where he says he tried it??  I searched the forum for Epipen and saw Counterpoints say that he owned one, but didn't see him say that he had ever used it.  Unfortunately we can't ask him because somebody banned him.

I've never used an epipen, and they're dangerous to try when not absolutely necessary so don't be a hero, but I'm fairly confident we'd feel instantly better.  Anyone else have experience with an epipen??

That's quite interesting ; there is basicly two main theories right now and the epipen thing could give us some relevant informations ;

If POIS is histamine related, we'll get instant relief with epinephrine
If POIS is migraine/blood pressure related epinephrine (more than 0,1 µg/kg) will just make symptoms much worse by raising blood pressure and constrict brain vessels

 

Offline kurtosis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17411 on: 12/12/2012 10:03:00 »
One problem is that POIS appears to have "flu like" symptoms which are different from post-coital headache. Flunarizine / sibelium isn't just a treatment for headaches. It has a range of effects including.
Quote
Flunarizine is a non-selective calcium entry blocker with COMBOLMIN binding properties and histamine H1 blocking activity
.

Similarly Ketotifen has a few different effects.
Quote
Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabiliser
...
 Besides its anti-histaminic activity, it is also a functional leukotriene antagonist and a phosphodiesterase inhibitor. The drug may also help relieve the symptoms of IBS.

I'm not sure that doctors know precisely why flunarizine works as a migraine prophylactic or all the effects of ketotifen. There's always ongoing research on conditions such as migraine where the aetiology isn't viewed as "solved".
Equally, too much epinephrine could kill you so it's not a case of EPI works or doesn't work. The right dose may improve symptoms, the wrong dose may prove fatal...
 

Offline RASSIA

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17412 on: 14/12/2012 10:00:33 »
you still believe allergic to semen?
 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17413 on: 14/12/2012 18:20:10 »
you still believe allergic to semen?

There are different types of POIS. I've read ~90% of the posts here (and a fair amount at the links you posted) and considering all that I've learned I think it's highly possible that at least some of us have an allergy/autoimmune reaction related to semen or orgasm/ejaculation. Chronic autoimmunity can lead to hormone/neurotransmitter imbalances as well as other dysfunctions.

Nobody "knows how to treat POIS" at this point. Right now the best source of data for fellow sufferers is our POIS forums.
« Last Edit: 14/12/2012 18:25:53 by Vincent M »
 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17414 on: 15/12/2012 14:01:48 »
Dr. Richards knows how to treat a pois

Did he treat your POIS? Are you cured? What were your exact symptoms and which treatments relieved which symptoms? How long have these treatments been working to resolve your symptoms and how long did you have to take them before they began working?
« Last Edit: 15/12/2012 14:06:23 by Vincent M »
 

Offline RASSIA

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17415 on: 15/12/2012 14:12:23 »
good luck to all!
 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17416 on: 15/12/2012 14:33:45 »
после секса слабая память ,  рассеянность, тошнота ,слабость теле плохое зрение трудно запомнить слова слабые мыщцы это длится неделя


It seems that you listed your symptoms. In Russian. Okay. Could you please answer my other questions, preferably in English?
 

Offline RASSIA

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17417 on: 15/12/2012 15:54:38 »
after sex, poor memory, confusion, nausea, weakness, body low vision is difficult to remember the words weak muscles ...
 

Offline RASSIA

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17418 on: 15/12/2012 16:13:13 »
Shawn Davis, Customer Support
  |  Anonymous
The idea of this very site came as a consequence of the sexual exhaustion I experienced myself at my twenty eights.

The symptoms were of wide range so I used to circle around numerous type of specialists for every issue. My erectile dysfunction issues bothered me and was depressing me so greatly that I went through 11 urologists total, I think, even after stumbled on dr. Richards. However, the methods of dr.Richards were the only ones that proved to work as the time passed by. I grew extremely sympathetic to the issue so I circled around the forums trying help sufferers the best I can before I hired a guy to make this website, which was nothing more than a common blog with medical information at first. It was not helping that much, though, since the problems of most of the guys differed greatly so I talked with dr. Richards himself if he could possibly share some insight and he agreed.

At first he wrote just a couple of articles but then responses and questions from guys all over the world appeared. He started answering some of them in his spare time, recommending existing practices and supplements that used to work in the past for his patients. The problem with the products was that even combined they were not the exact thing he had in mind in order to be effective at their full potential. Most of the formulas were then tweaked heavily, thus creating unique products for this purpose alone. The process is an ongoing one and the products are ever-changing, even now. Recently we managed to combine most of the benefits of VE-Cream and SR-Cream in just 1 product, as well as BC-Liver and SF-Liver, Multi-B and Multi-A and B-Amino and A-Amino. Most of the other products have also been improved but not in such a drastic manner.

The issue of Sexual Exhaustion is widely unrecognized in the medical community, and is the reason to why the site kept operating without the full credentials (and even now is but I was recently allowed to publish some additional information) of dr.Richards for a long time. You can only imagine the heavy burden on ones shoulders for opening a huge public dispute on a still unrecognized syndrome. The doctor reassured me, though, that has slightly lowered his active working hours in order to concentrate on his research and continue his book on the subject that he's been writing for some time now.

For any observations, questions or suggestions, please feel free to contact our customer support by email or fax at:

Phone numbers removed - mod
« Last Edit: 15/12/2012 20:10:45 by JP »
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17419 on: 15/12/2012 17:43:01 »
website selling commercial products removed - mod

we get the point, stop posting those websites.
« Last Edit: 15/12/2012 20:11:10 by JP »
 

Offline JP

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17420 on: 15/12/2012 20:12:06 »
Rassia, please stop posting links to website promoting commercial interests.  If you'd like to have a discussion of the science behind those treatments, this is the place to do so.  If you'd rather promote someone's commercial interests, please take it elsewhere.

-JP moderator
 

Offline Kingkong

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17421 on: 15/12/2012 23:21:07 »
Hi Rassia, I'M a french guy from Canada. I most say that I didn't understand your english. Sorry but you have to be more clear
 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17422 on: 16/12/2012 15:13:53 »
after sex, poor memory, confusion, nausea, weakness, body low vision is difficult to remember the words weak muscles ...

Rassia, yes those are POIS symptoms. Again I ask you: Are you cured? Which treatments relieved which symptoms? How long have these treatments been working to resolve your symptoms and how long did you have to take them before they began working?

Sorry if I sound aggressive, but if you've found something that is helping your POIS I hope you'll share with us specifically what herb/supplement/treatment protocol or medication it is.
« Last Edit: 16/12/2012 15:24:53 by Vincent M »
 

Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17423 on: 19/12/2012 09:43:02 »
I cant remember the logic given by that doctor who initially recommended niacin to dampen down pois symptoms, but I have been reading some site regarding MTHFR mutation, and I see people on the protocols to stabilize or kick start their methylation cycle (Detoxification + Controlling inflammation + Mood balancing + Energy production + Immune function), use Niacin to create the flush to deal with symptoms caused by taking too much of their supplements and causing over methylation. (the symptoms are not too dissimilar to pois I thought)
« Last Edit: 19/12/2012 09:45:47 by acronym »
 

Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17424 on: 19/12/2012 10:03:34 »
From a doctor specialising in MHTR + methylation....
"Niacin speeds up COMT which is one reason why it also may be useful. If one speeds up COMT, then things like dopamine and epinephrine get broken down faster. Niacin also is a ‘sponge’ for methyl groups, namely SAMe, because SAMe is required to metabolize niacin."  COMT is Catechol-O-Methyltransferase enzyme.
I know this goes against a number of us who feel we are low in dopamine. I can understand why our body is flooded with it during sex/arousal, but why if it is not broken down properly it would it make up feel days later like we are low in it.
 

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #17424 on: 19/12/2012 10:03:34 »

 

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