[Quasar]

@Lapoisse2

It's interesting. So, that Nsaid has 2 functions i suppose: 1) reduce headache pain (like any Nsaid) and 2) reduce vessels vasospam or constriction/dilation.  It's interesting because i think both mechanisms could be related. I remember having some success with Nsaids and also Paracetamol. One doctor recommended me once to take Propranolol.

Well, going back to my tonsils topic, i've made a new Poll here: http://poiscenter.com/forums/index.php?topic=946.0

[Nightingale]

Still have my tonsils.  I have been diagnosed with mild sleep apnea, but it subsided with stopping a certain med.

I too will say what B_Daniel said: there have been quite a few people who have cured themselves only to come back later and say it just helped.  I don't want to ruin the party, but put it in perspective.  It could be temporary.

[Quasar]

@Nightingale

Thats true. I'll never know if it will come back (hope not!). It's been 2 months. If it comes back i'll tell this forum ASAP.

[kurtosis]

Just a question : My doc who knows this condition(for him it's a form of Post coital head haches) want to have a close look to my brain vessels with the MRI  numeric capture(the DVD) to see if there is anomaly ; Has anybody had this kind of precise verification ?

I really think this is a great idea. I had an MRI and they didn't find any obvious problem but I guess it may have been more useful to have the MRI immediately after an O. I had allowed 3 hours to elapse for obvious reasons. I was in work that day... :)

However, I've always felt that part of my POIS was blood vessel related and I sometimes get mild headache symptoms that sometimes develop into migraines. It's rare but I don't think it's completely unrelated to my POIS.

So a question is what of the chemical cocktail that changes during an erection and following an O causes blood vessels to dilate or constrict?
Histamine is one neurotransmitter that does this. The Calcium channel also has an effect. Is POIS related to hypertension? Is there reduced NO production. All interesting questions to be explored with the help of a willing and interested neurologist.

For instance, have a look at supplements that cause vasodilation.
http://www.ehow.com/about_6615780_supplements-dilate-blood-vessels.html
Niacin, Vitamin C, Magnesium, etc. Ring any bells?
You could add ginkgo and l-arginine to this list. These are all things that have brought about some POIS relief for people. It's an interesting thought... :)

[helloworld]

Hello everyone again -- I see that no one replied to my post awhile back, as at that time, everyone was posting about funding research into POIS. I still say, if you are feeling this way, try what I do which has been working for months for me -- it's given me a lot more energy and my sex drive has increased dramatically without the symptoms of POIS. I used to wait two weeks before having sex because of the way I felt, now I can have it daily and still feel that drive the next day with barely any POIS symptoms. You can try all of these supplements, but if you do what I do, you'll get all of that plus so much more. Here's part of my original post -- I really suggest you try it for at least a month and see the results you obtain. What I've found that works consistently to speed up feeling "normal" again is blending (not juicing) the following: kale (about a cereal bowl full -- make sure it's organic -- look up the 'dirty dozen',) blueberries (about one handful), strawberries(4-6), 2 bananas, Hershey's cocoa (non-alkalized -- about two teaspoons,) 1 celery stalk (organic -- look up the 'dirty dozen',) baby leaf spinach (about half a cereal bowl - organic -- look up the 'dirty dozen',) red globe grapes (seeded, including the seeds, about 10-15 grapes) and a half red bell pepper. I generally make about 4 full mugs full and drink it in one sitting. If you try this, be warned, your stool will be quite unpleasant the first one or two days. But one caveat -- be careful if you're on a low-oxalic diet, spinach and kale, and the berries do have a lot of oxalic acid. Hope this helps some people.

I've recently added organic grapefruit, oranges, red delicious apples, Ceylon and Indonesian cinnamon (not siagon -- too much coumarin for the dosage I use and the frequency that I use it.) Does it taste good? No. It's awful -- you're tongue doesn't know where to begin to describe all the types of taste. But it's loaded with just about every nutritional element your body needs. Blend it for at least 3 minutes on high -- as cellulose it tough to break down, and use a tight seal glass jar to keep a drink ready for the morning. Also, when drinking, keep the juice in your mouth for a few seconds to mix it with your salivary enzymes like ptyalin. Also, add some raw, un-roasted almonds, walnuts and cashews to chew on while drinking this -- the fat in the nuts help bind fat soluble vitamins.

[kurtosis]

Interesting Hellworld.
Have you tried taking part of your ingredients and seeing what effects you get?
It's a complicated cocktail to just arrive at by accident :)

For example, I eat a lot of blueberries and have found that they appear to have positive effects on my sinusitis and memory. This may be due to flavanoids but I think the scientific consensus on these are "promising but more research needed".

http://www.scientificamerican.com/article.cfm?id=your-brain-on-blueberries

http://www.webmd.com/alzheimers/news/20100121/blueberry-juice-may-boost-memory

I found blueberries mentioned on some fora as useful for home remedies for treating sinus infections but it's not exactly peer reviewed publication material :)

[Quasar]

@demo

So, i just made a 50$ donation to Nord. Is not a lot, but i hope it helps, and maybe i make more donations in the future :)

[Kingkong]

I still have my tonsils, but I haven't had any problems with them that I'm aware of. I haven't been tested for sleep apnea so I suppose it's a possibility.

I don't have my tonsils since I was 10 years old. I'm 53 now. And I have POIS. I should say that I have a saliva gland removed in 2004 because it was producing stones of calcium. Also, I stopped taking flunarizine yesterday. The sides effects were too hard for me. The sides effects were: fatigue, concentration's difficulties. I was sleeping 12 hours a day and it was'nt enough. I had also muscular pain. But I must say that flunarizine was very efficient for my POIS and my headache. I usually have headache 3-4 times a week. So I took flunarizine from november 19th to january 16th. Also, I sent my saliva sample to 23andME. They said that I will have my results at the end of febuary.

[RalphW]

I've been a POIS sufferer for many years. Here's a bit of my history:
3 major concussions in my youth, masturbated frequently from the age of 13, extremely shy and anxious since childhood.

I started having headache/brain fog symptoms around age 25. My other symptoms include nausea, sinus congestion and tiredness. The brain fog is the worst part as communicating and focusing are difficult. Symptoms happen about one hour after ejaculation and last for days. The only time I can remember being symptom free is many years ago when my girlfriend went away traveling for a few months and I must have abstained or severely reduced my ejaculation frequency. I get less severe symptoms if I have sex but don't ejaculate.
   
I have been taking an MOAI anti-depressant for the last 10 years to treat social anxiety and depression. I have sleep apnea which is being treated. The scan they took showed excessive fluid levels in my sinus cavities but nothing more was said about that from the doctor.
Since reading this forum I have started taking Methionine, NAC (N - ACETYL CYSTEINE) and I'm about to start niacin. It's just been a week so no change yet.
Hopefully a cure will happen soon!     
 

[helloworld]

kurtosis, I did try that at one point, but due to the daily demands in my life, I really didn't have the time to do so. I kinda have to beg to get 30 minutes just to prep/blend/clean with everything going on in my life at the moment. I will say this though, it did take sometime, about two weeks until I started to feel this way, i.e., feeling like my normal self, and having my sex drive return to an age about 15 years younger. Regardless of the specific components involved here for that particular effect, I'm doing this as a comprehensive approach for better health overall. I browsed many nutritional sites and read many books over the years, and found whfoods.com to offer a good amount of info on specific vegetables and fruits, and based on my personal research, I decided to go with that mix (occasionally, I'll also add in limes (love the taste of them) or lemons and baby carrots.) Quick note, I decided on blending because it's the only way I'm going to realistically eat all of this. Prior to this, whenever I did this, I start with the best of intentions and wind up a few days later only eating the convenient things (like blueberries/strawberries on cereal) and have the other items rot because I was to lazy to actually prepare a salad. But when I did do a salad, I still couldn't "eat" the amount I get by blending, let alone this kind of combination, and in addition, using dressing, the salad just kind of laid in my stomach for hours. Doing it this way, it just works for me, and I get my fiber + very easy clean-up compared to juicing, as there's no waste.

Again, no one here has anything to lose, other than possibly excess weight if they give it try with the potential to feel normal after orgasm + you'll be all the more healthier for doing so.

Have you tried taking part of your ingredients and seeing what effects you get?
It's a complicated cocktail to just arrive at by accident :)

[Nightingale]

I've been a POIS sufferer for many years. Here's a bit of my history:
3 major concussions in my youth, masturbated frequently from the age of 13, extremely shy and anxious since childhood.

I started having headache/brain fog symptoms around age 25. My other symptoms include nausea, sinus congestion and tiredness. The brain fog is the worst part as communicating and focusing are difficult. Symptoms happen about one hour after ejaculation and last for days. The only time I can remember being symptom free is many years ago when my girlfriend went away traveling for a few months and I must have abstained or severely reduced my ejaculation frequency. I get less severe symptoms if I have sex but don't ejaculate.
   
I have been taking an MOAI anti-depressant for the last 10 years to treat social anxiety and depression. I have sleep apnea which is being treated. The scan they took showed excessive fluid levels in my sinus cavities but nothing more was said about that from the doctor.
Since reading this forum I have started taking Methionine, NAC (N - ACETYL CYSTEINE) and I'm about to start niacin. It's just been a week so no change yet.
Hopefully a cure will happen soon!     
 

Hi and welcome!  I'm glad you introduced yourself.  You definitely sound like you have POIS.  The biggest thing that has changed my life in regards to POIS has been the use of the niacin flush before orgasm.  That's the only real relief I have besides abstinence.

You are the first person I know to be taking MAOI's.  Those went out of style once they SSRI's came out, but are used when symptoms are so severe that it's worth dealing with the side effects.  I have been dealing with depression for nearly 10 years as well as bipolar type II.  I have unpleasant dreams with SSRI's, so I don't take them.  I had to spend 3 years in hospitals and group homes to overcome my severe depression and intermittent psychosis.  Have you ever been manic or psychotic?  I take an antipsychotic every day along with a benzodiazapine for anxiety.  Oh and lithium for bipolar (which actually is helping me with its antidepressant properties.

Induce that niacin flush (like get HOT and RED!), wait 20-30 min after the peak, and then have your orgasm.  I'm quite confident you will find relief!

[Vincent M]

Nightingale, have you ever tried taking only the benzo without the antipsychotic and the lithium? And if so for how long were you only on the benzo?

Also was there a time when you were on the other two drugs without the benzo?

For me benzos have amazing anxiolytic and antidepressant effects where as actual "antidepressant" class drugs just make all of my POIS symptoms worse. In my reading on the subject I've found that this is also the case for many other people.

I suspect that it is the benzo that is actually helping you and the other drugs are probably just making you feel worse. In addition the benzo could be masking the side effects of the other drugs since it's a CNS depressant.

[nathan123]

Hi, Another interesting fact, I found.  Today I made absolute eosinophil count.  Interesting to see that normal range is 20 to 500.  Whereas my observed value is 1520.  three times higher than the maximum limit.  Is any body has made this AEC blood test.  What does it mean?

[Vincent M]

"An absolute eosinophil count is a blood test that measures the number of white blood cells called eosinophils. Eosinophils become active when you have certain allergic diseases, infections, and other medical conditions.

Certain medicines may cause you to have an increase in eosinophils. Such medicines include:

Amphetamines (appetite suppressants)
Certain laxatives containing psyllium
Certain antibiotics
Interferon
Tranquilizers

High numbers of eosinophils (eosinophilia) are usually associated with allergic diseases and infections from parasites such as worms. A high eosinophil count may be due to:

Asthma
Autoimmune diseases
Eczema
Hay fever
Leukemia"

http://www.nlm.nih.gov/medlineplus/ency/article/003649.htm

It's interesting that yours was that high. Where did you get this blood test and were there any comments about it on the lab report?

[RalphW]

Hi and welcome!  I'm glad you introduced yourself.  You definitely sound like you have POIS.  The biggest thing that has changed my life in regards to POIS has been the use of the niacin flush before orgasm.  That's the only real relief I have besides abstinence.

You are the first person I know to be taking MAOI's.  Those went out of style once they SSRI's came out, but are used when symptoms are so severe that it's worth dealing with the side effects.  I have been dealing with depression for nearly 10 years as well as bipolar type II.  I have unpleasant dreams with SSRI's, so I don't take them.  I had to spend 3 years in hospitals and group homes to overcome my severe depression and intermittent psychosis.  Have you ever been manic or psychotic?  I take an antipsychotic every day along with a benzodiazapine for anxiety.  Oh and lithium for bipolar (which actually is helping me with its antidepressant properties.

Induce that niacin flush (like get HOT and RED!), wait 20-30 min after the peak, and then have your orgasm.  I'm quite confident you will find relief!

Thanks for the welcome. The MAOI I am taking (Phenelzine) is used quite often to treat social phobia. I did try every other type of anti-depressant first but none worked as well as the Phenelzine. I had one psychotic episode while on Phenelzine a few years ago. Not sure if it was a serotonin syndrom type episode but I had recently had surgery so I was using pain killers, NSAI's, and was under a lot of stress financially from being off work. This happened two years ago and I was prescribed a small dose (150mg/day) of trileptal after the eposide. Things have been stable mentally since then. Pois is the same as always. I also take 1mg/day clonazapam for anxiety.

I get headaches from taking the supplement l-arginine and also from hot tubs. These headaches are similar to a POIS headache. I thought these may be caused by vaso-dilation as my blood pressure in normally on the low side. I can't find any natural vaso-restrictors that would be safe with the phenelzine.

What type of niacin and what dose is recommended before O?

[Gbolduev]

Nathan,  You are the one  taking  calcium channel blocker?  If it helps you , it means that   your TSH is below 1.5  and also means that  you are in   infection POIS,    same as that  tonsil guy.    Eosinophils  are included  in my  tests that I require on the Russian forum. Do the eucalyptus  enemas, and kill the parasites.   High eosinophils  -- most likely  parasites,   low eosinophils-  most likely  acute infection.

[Nightingale]

Hi Vincent,

You bring up interesting points.  My current psychiatrist and I are working on tapering me off my antipsychotic, and I'm finding I need to take more clonipin to deal with the reemerging symptoms of anxiety and distractability.  I have many problems that have devolped over the past 5-6 years while taking antipsychotics and mood stabilizers, and no one has a great explanation as to why except that the meds themselves are causing them.

I was so turned off to using clonipin when I was first prescribed it 5 years ago because I had seen so many peers of mine who had abused benzos and I didn't want to start on that track.  Now, I realized I have a good (maybe better?) head on my shoulders than those peers, so I have begun to take advantage of clonipin's wonderful effects.  It works very well, and has added no other side effects yet.

Just to be clear: yes, I was on the two other drugs before the benzo

And no: I have not tried just the benzo without the other drugs, because I have never successfully withdrawn from my antipsychotic without going back into psychosis. BUT I never used the clonipin to its full capabilities.

You really bring up something I am right in the middle of hashing out, which is interesting.  I really needed some serious help from psychiatric meds back in the day, but I have recovered from those hard times and I'm trying to remove whatever unnecessary medications I am currently taking.

[Nightingale]

How are your side effects from your MAOI?  I have never had a doctor offer to try me on one, and I figured that the side effects were a major trade off...  I too have social phobia but I'm curious about how it felt the first time you realized the MAOI helped.  SSRIs never had a real positive effect for me, I just kept taking them because I believed my depression was so severe I couldn't discern if they weren't helping and that my pain was just too strong.

I get headaches from taking the supplement l-arginine and also from hot tubs. These headaches are similar to a POIS headache. I thought these may be caused by vaso-dilation as my blood pressure in normally on the low side. I can't find any natural vaso-restrictors that would be safe with the phenelzine.

What type of niacin and what dose is recommended before O?

I too can't handle l-arginine, as well as any of the supplements that upregulate the amount of dopamine in my body.  Nor can I handle even herbs that increase nitric oxide production.  Interesting?

[Mer]

That is a very good news!! How about brain fog? Did you have brain fog before? Is your brain fog gone now?

90 %? So whats left?

Nothing really as important: just some stomach pain and bloatness, but nothing really serious. My main issue was the headache, fatigue and pshychological symptoms that lasted for days. And all of that is solved :)

[Vincent M]

Nightingale,

I see. I haven't tried antipsychotics and I haven't read extensively on them, but I'd advise you to take as little as possible of the klonopin. I took it for a few months a few times a week, although at a dosage of 2 or 3 mgs, and I'm pretty sure it made my base anxiety level slightly permanently worse. I've read stories of doctors suddenly taking patients off of benzos so I decided to save some for rainy days ahead.

[B_Daniel]

What I've found that works consistently to speed up feeling "normal" again is blending (not juicing) the following: kale (about a cereal bowl full -- make sure it's organic -- look up the 'dirty dozen',) blueberries (about one handful), strawberries(4-6), 2 bananas, Hershey's cocoa (non-alkalized -- about two teaspoons,) 1 celery stalk (organic -- look up the 'dirty dozen',) baby leaf spinach (about half a cereal bowl - organic -- look up the 'dirty dozen',) red globe grapes (seeded, including the seeds, about 10-15 grapes) and a half red bell pepper. I generally make about 4 full mugs full and drink it in one sitting.

I believe that works for you but that's just such an insane amount of stuff.  4 full mugs?!?  If you could figure out what the vitamin equivalents of those fruits/vegetables are and see if that works, we'd be getting somewhere.  Then eliminate one per week and see which you don't need.  It'd likely take 6 months to get to the bottom of it, but the result would be something manageable. 

[B_Daniel]

Also, I sent my saliva sample to 23andME. They said that I will have my results at the end of febuary.

sweeet!  will be interesting to see if we have any similar areas with genetic mutations.

[kurtosis]

I too can't handle l-arginine, as well as any of the supplements that upregulate the amount of dopamine in my body.  Nor can I handle even herbs that increase nitric oxide production.  Interesting?

Hi Nightingale,
Can you explain what you mean by not being able to handle herbs that increase nitric oxide production?
One problem is that herbs don't do one thing. They are not targetted pharmaceuticals. For instance you can get COMT inhibition effects with ginkgo and also MAO inhibition aswell from quercetin (which is part of standardised ginkgo extract).

See
http://rudyrides.files.wordpress.com/2010/08/ginkgo_tbi2.pdf

"GBE exerts transmitter/receptor effects that are likely mediated via radical scavenging/inhibition, hemodynamic/metabolic modulation, PAF antagonism, MAO and COMT inhibition..."

http://www.ncbi.nlm.nih.gov/pubmed/10983836?dopt=Abstract
http://www.ncbi.nlm.nih.gov/pubmed/17497242
and
http://en.wikipedia.org/wiki/Quercetin#Monoamine-oxidase_inhibitor
Herbs are literally a mixed bag :)
They can have some good and bad effects. Then there's supplement manufacturers who add a mix of herbs to a product in a really non-specific way. You've got to be careful mixing herbs and drugs.

There's a lot of info about ginkgo's effects here
http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?pt=100&id=333&ds=mechanism

[nathan123]

Hi Everyone,

From the last two and half months, I am taking Calcium Channel Blocker.  It worked very well for me and relieved my POIS almost 80%.  But one disadvantage if it increased my weight heavily and I reached 100 kg.  So, I decided to stop taking Calcium Channel Blocker. 

Joining new therapy from tomorrow for POIS cured.  If it is worked out I will post

[Nightingale]

RalphW, I forgot to say about the niacin:  take actual niacin, not No-flush niacin which is niacinamide.