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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6457768 times)

Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18350 on: 21/06/2013 05:25:49 »
my symptoms changed completly and i dont expiereince knee pain what so ever like it was never existed.knee pain replaced by abdomen pain

Do you know of any reason why your knee pain might have disappeared?
Dont know exactly but when i remained ill (hepatitis a) for 3 months after that when i recovered from illness knee pain was not there.
 

Offline RD

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18351 on: 21/06/2013 16:49:12 »
... Dont know exactly but when i remained ill (hepatitis a) for 3 months after that when i recovered from illness knee pain was not there.

If you are looking for an organic illness which connects hepatitis and knee [joint] pain, try "cryoglobulinemic vasculitis" ... http://www.ncbi.nlm.nih.gov/pubmed/18281853  [ arthralgia = joint pain ]
« Last Edit: 21/06/2013 16:52:23 by RD »
 

Offline nathan123

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18352 on: 21/06/2013 19:25:10 »
Hi it has been a long time to posted in the forum. 

From the blessings of god, my POIS not bounced back and enjoying third month of POIS free life.  Having O around three times a weak.   Feeling enrgetic, calm and cool. 

Further, during POIS period, I noticed premature ejaculation in me.  But after two months of POIS free life, this problem also gone now.

I would post next post in next month
 

Offline happy2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18353 on: 21/06/2013 19:43:22 »
Hi everybody, I'm new to the forum.  I have been dealing with POIS syndrome since I was in high school.  I'm now 32.  As of last year, September of 2012, I found this forum and it was only then I knew I had this disorder all these years.

Great post, happy2. I love reading about which supplements/treatments members have found to be of benefit. Definitely try the claritin at least an hour before orgasm; benadryl should work a little faster. It seems to me that a lot of the benefit I gained from those two antihistamines was due to better quality and longer sleep. I have a question for you. What exactly are your POIS symptoms? For instance I have burning eyes and joint pain after orgasm, which not many of us experience.

Also you said that you take flush free niacin; just want to make sure you're aware that most members have required the flush in order to experience the full effect of niacin.

Thanks Vincent M.

It's really good to be a part of the effort in finding a treatment for this disorder.  My POIS symptoms are joint pain, including fingers, neck, back, and knees.  The cognitive symptoms for me are by far the worst though.  They include brain fog, "can't find the right words" when talking to people.  I can do almost anything with POIS, including hard labor, and I have seen others post that intensive exercise helps also.  The only thing I can not do is be around people and do anything that causes me to be around other people in social interaction type settings.  This in itself is extremely debilitating, and it is probably by far the most debilitating factor when dealing with POIS.  That, to me, is probably why POIS should be classified as a mental disorder.  I believe it is an allergy, as I have found tremendous relief from the more severe symptoms by taking anti-histamines.  I wanted to ask you a question, or anyone else who gets this message.  It's about the Niacin with a flush.  I have been taking flush-free Niacin.  OK.  When do I ingest the flush Niacin?  Is it before orgasm, and if so, how long before?  I think I remember someone said that once the flush occurs, after about 30 minutes, then it's safe to go.  My only thing is that I've been taking the flush-free every day because I'm surviving on nocturnal emissions alone, and have been for a long, long time.  If there's a better way I'd like to know.  Thanks.  If I could find the cure by taking something before orgasm, then that might be better than waiting for the nocturnal emissions and taking something after.

Happy2
 

Offline happy2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18354 on: 21/06/2013 19:45:28 »

Thanks B_Jim,

7-8 days was the maximum amount I had last year.  I also had some 5-6 day symptoms also sometimes.  The Benadryl and Claritin have worked really well immediately following orgasm.  I don't know if I have the cohoneys to try to alter that system.  I will definitely try to take some of the above medications before orgasm however, and see if I can maximize the effect even greater.  Thanks for the post.

Claritin has a delay of 2 hours to be active. Take claritin 2h-2h30 before orgasm and you will have the maximum effect. This is confirmed by canadian website.
On the canadian website I see they made claritine "ultra-fondant", a quick effect version of claritin. The med is used by sublingual way.

Thanks B_Jim,

That helps a lot.
 

Offline Prancer

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18355 on: 22/06/2013 00:29:26 »
I'm also more timid around people during POIS, even though I enjoy being with companions. It seems a lot of us share similar personality traits. Sometimes I wonder if something about our similarities causes POIS or if POIS causes our similarities.
« Last Edit: 22/06/2013 03:16:18 by Prancer »
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18356 on: 22/06/2013 16:59:20 »
This is my new supplementation regimen

Magnesium consumption used to be low, but now I am going for  420 mg or maybe more (yet not in excess) due to my joint pain after O and it's apparent role in treating osteoporosis and dopamine boosting since dopamine is needed to reduce prolactin at the moment of orgasm. Prolactin is attributed to disrupting neoruhormonal balance by reducing testosterone, etc. and increases after O.The tuberoinfundibular DA system inhibits prolactin synthesis and release from the anterior pituitary. Antipsychotic drugs, which antagonize D2 receptors, elevate levels of prolactin. Conversely, D2 receptor agonists, such as bromocriptine, can be used to suppress hyperprolactemia, which is most commonly caused by prolactin-secreting pituitary adenomas I also supplemented amino acids and iron.Catecholamine biosynthesis begins with dietary tyrosine, which is actively transported into the brain (or peripheral sympathetic neurons). It is hydroxylated within neurons at the 3 position by the enzyme tyrosine hydroxylase (TH) to form dihydroxyphenylalanine (dopa). TH requires Fe2+ as a cofactor, as well as molecular oxygen and tetrahydrobiopterin (a hydrogen donor). An inhibitor of TH, α-methylparatyrosine (AMPT) has been used historically as an experimental tool to study catecholamine function; more recent alternatives include mice genetically engineered to lack TH or other enzymes in the biosynthetic pathway.Meat is a poor amino acid source not only for the synthetic hormones it contains , but also because the human digestive system is not acidic enough to decompose meat like carnivores, and can cause immunologic issues in IBD patients like me. Soy protein reduces testosterone by increasing estrogen, reduces zinc absorbtion and disrupts tyroid function so I stopped soy protein. http://www.ncbi.nlm.nih.gov/pubmed/16571087  http://www.ncbi.nlm.nih.gov/pubmed/3559747
That is why supplements of protein/amino acids work better for me. B complex vitamins are part of my diet. I also consume olive oil wich contains building blocks of hormones and vitamin D is essential for increasing testosterone and serotonin etc.. Zinc supplementaion was the most noticable improvement since after it's supplementation I have nocturnal emmissions of 80% less symptoms.
 

Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18357 on: 22/06/2013 17:45:47 »
DENIED,

Just do the  testing and stop guessing.   There is a program  that I suggested which  contains everything  that you mentioned for POIS. And some people are on it and feeling better, but  for everybody there is  their own program., since POIS  is not the same thing for everyone.  Estrogen dominance  is not the only your reason .
POIS is  too much or too low  acetylcholine..    High thyroid high dopamine high progesterone   low acetylcholine,   low  thyroid  low dopamine low progesterone high acetylcholine.
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18358 on: 22/06/2013 22:53:44 »
DENIED,

Just do the  testing and stop guessing.   There is a program  that I suggested which  contains everything  that you mentioned for POIS. And some people are on it and feeling better, but  for everybody there is  their own program., since POIS  is not the same thing for everyone.  Estrogen dominance  is not the only your reason .
POIS is  too much or too low  acetylcholine..    High thyroid high dopamine high progesterone   low acetylcholine,   low  thyroid  low dopamine low progesterone high acetylcholine.

What program? What testing should I conduct and why?

I forgot to say I supplement manganese to 22mg, it increases LH, promoting testosterone production etc. I am placing some importance to testosterone because of my poor muscle mass that I must icrease fast due to injury and my low T.
I also use H2 antagonist zantac because of this http://www.ncbi.nlm.nih.gov/pubmed/9088875
on full blown POIS.
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18359 on: 23/06/2013 00:07:05 »
Testosterone importance http://www.ncbi.nlm.nih.gov/pubmed/21693622
http://www.ncbi.nlm.nih.gov/pubmed/15240608

Nsaids inhibit COX 1 and COX 2 inhibiting prostaglandin H2 formation.
 

Offline Gbolduev

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18360 on: 23/06/2013 00:35:04 »
Denied,

If you carefully  read this forum you would know that I posted   different programs for different POIS  cases ,  it looks like you are taking one of my postings.   I hope it matches  your  body chemistry.   Manganese  raises acetylcholine, which raises  DHT. Manganese  raises  sodium level. Zinc chelates manganese.  To take manganese  and zinc you need certain ratio. The most important ratio in  your cell is  NA/K .  So  if you know where you are on that ratio, then you can take minerals.

They are 2 cases,     low acetycholine   high testosterone ,  low DHT  ----POIS is caused by low DHT.  Try to give  low DHT person  saw palmetto..you will go right into  POIS.

secondly,  there is high acetylcholine ,  low testosterone  high DHT high estrogen ---symptoms are caused by low testosterone.

Good luck ,

I hope it  helps

It is good that someone is using manganese for a change.
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18361 on: 23/06/2013 01:38:18 »
Denied,

If you carefully  read this forum you would know that I posted   different programs for different POIS  cases ,  it looks like you are taking one of my postings.   I hope it matches  your  body chemistry.   Manganese  raises acetylcholine, which raises  DHT. Manganese  raises  sodium level. Zinc chelates manganese.  To take manganese  and zinc you need certain ratio. The most important ratio in  your cell is  NA/K .  So  if you know where you are on that ratio, then you can take minerals.

They are 2 cases,     low acetycholine   high testosterone ,  low DHT  ----POIS is caused by low DHT.  Try to give  low DHT person  saw palmetto..you will go right into  POIS.

secondly,  there is high acetylcholine ,  low testosterone  high DHT high estrogen ---symptoms are caused by low testosterone.

Good luck ,

I hope it  helps

It is good that someone is using manganese for a change.
High DHT apparently fits in with the rest of the puzzle.  DHT is the one that does most to promote erections, especially spontaneous ones and those experienced during REM sleep and wet dreams. I was looking for an answer to that, you indeed have helped me. I was suspecting high acetycholine for quite some time, but could not find a way to explain every single reason, how it worked and how to fix it naturally. Now I think I know what to do.
 

Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18362 on: 23/06/2013 12:12:22 »
My name is Jonas and i´m new to this forum, i like to get in touch with other poisers living in Sweden or Stockholm.

My symtoms are:

Burning eyes
Bloated stomach
Flulike state
Severe fatigue
Very sluggish cognitively
Lack of concentration
Confusion
Dizziness
Headaches
Extreme anxiety/depression
Sore muscles
Memory problems
Difficulty breathing
Difficulty sleeping
Bad temper
Lack of libido.


The symptoms last for two weeks. I have had this symptoms for about 15-18 years. I have contacted a expert in sexual medicine here in Stockholm. If you live in Stockholm or in Sweden, feel free to contact me.

So far i have tried :

Cortison
Antihistamines
Testosterone gel
And also blood tests to look for inflammation, no luck so far.



« Last Edit: 25/06/2013 13:36:07 by Jonas STHLM »
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18363 on: 24/06/2013 01:23:35 »
I have some recent tests here done for testing looking for a way to explain weight loss, possibly thanks to POIS, but I also did a CT scan and my intestines look fine, and no problems in gonads, seminal vesicles nor prostate, they even commented my seminal vesicles were in "EXCELLENT CONDITION" salting the wound.

Alkaline Phosphatase 78.00 IU/L
Sodium 144.0 MEQ/L
Potassium 4.40 MMOL/L
Chloride 105.0 MEQ/L
Calcium 10.0 MG/DL
CO2 28 MEQ/L
Creatinine 0.74 MG/DL
Bilirubin total 0.90 MG/DL
Globulin 2.50 GM/DL
Albumin 5.0 GM/DL
Total protein 7.50 G/DL
ALT 15.0 U/L
AST 16.0 U/L
BUN 8.0 MG/DL
GLUCOSE 92.00 MG/DL
 

Offline RD

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18364 on: 24/06/2013 04:22:03 »
I have some recent tests here done for testing looking for a way to explain weight loss ...

You previously said you have Crohn's , weight loss is typical in that disease because of malabsorption, and/or reluctance to eat because it causes pain ...

Quote from: wikipedia.org
Crohn's disease may manifest as weight loss, usually related to decreased food intake, since individuals with intestinal symptoms from Crohn's disease often feel better when they do not eat and might lose their appetite. People with extensive small intestine disease may also have malabsorption of carbohydrates or lipids, which can further exacerbate weight loss
http://en.wikipedia.org/wiki/Crohns_disease#Systemic
« Last Edit: 24/06/2013 04:27:00 by RD »
 

Offline Omen 30

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18365 on: 24/06/2013 05:47:59 »
Friends start taking b12 supplements atleast 500 mcg a day.it will take time atleast a month for the results.get your blood serum tested after a month if not much difference then go for the shots.
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18366 on: 24/06/2013 13:41:51 »
I have some recent tests here done for testing looking for a way to explain weight loss ...

You previously said you have Crohn's , weight loss is typical in that disease because of malabsorption, and/or reluctance to eat because it causes pain ...

Quote from: wikipedia.org
Crohn's disease may manifest as weight loss, usually related to decreased food intake, since individuals with intestinal symptoms from Crohn's disease often feel better when they do not eat and might lose their appetite. People with extensive small intestine disease may also have malabsorption of carbohydrates or lipids, which can further exacerbate weight loss
http://en.wikipedia.org/wiki/Crohns_disease#Systemic
Indeed, a CT scan was made to explain if I had a flare up (immune system attack causing inflammation, etc.). Maybe malabsorbtion of nutrients was the POIS problem all along. This could have caused  Now I need to find a way to justify the medical plan to cover further testing ( fake an illness?). I need now to fix the hormonal disaster Crohn caused. Reducind estrogen to bring down DHT and up Testosterone to healthy levels is the first step (I am a 18 year old with low testosterone, I already tested myself). Then find the mineral dosing appropriate to reduce acetycholine and increase GABA, wich requires testing. Not very sure about the testing required for finding out how to balance neurotransmitters though.
 

Offline RD

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18367 on: 24/06/2013 17:16:37 »
... I need now to fix the hormonal disaster Crohn caused. Reducind estrogen to bring down DHT and up Testosterone to healthy levels is the first step (I am a 18 year old with low testosterone, I already tested myself).

If you really have low testosterone, that too, like Crohn's, is possible via small-vessel vasculitis , ( rather than a consequence of Crohn's ) ... http://www.ncbi.nlm.nih.gov/pubmed/18609261


( fake an illness?)

Faking anything is just going to muddy the waters and damage your relationship with your healthcare providers and health insurance, faking is a very bad idea.
« Last Edit: 24/06/2013 17:29:43 by RD »
 

johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18368 on: 25/06/2013 08:24:22 »
The symptoms last for two weeks. I have had this symptoms for about 15-18 years. I have contacted a expert in sexual medicine here in Stockholm. If you live in Stockholm or in Sweden, feel free to contact me.

Hi im from Sthlm too, what do you need help with?
 

Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18369 on: 25/06/2013 12:58:02 »
The symptoms last for two weeks. I have had this symptoms for about 15-18 years. I have contacted a expert in sexual medicine here in Stockholm. If you live in Stockholm or in Sweden, feel free to contact me.

Hi im from Sthlm too, what do you need help with?

I´m interested to know if you have seeked treatment, if so were? Have you have had any success? If you want you can PM me in swedish.
 

johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18370 on: 25/06/2013 16:03:58 »
Last year i seeked treatment only to be met by complete ignorance, this fall i have an apointment with a allergy specialist doctor.
 

Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18371 on: 25/06/2013 17:08:35 »
Last year i seeked treatment only to be met by complete ignorance, this fall i have an apointment with a allergy specialist doctor.

Interesting, i have looking for a allergy specialist doctor in Stockholm, are you willing to share who you are going to?

I have seeked treatment at the centre for andrology and sexual medicine Karolinska Huddinge.

/J
« Last Edit: 25/06/2013 19:16:35 by Jonas STHLM »
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18372 on: 25/06/2013 17:14:25 »
... I need now to fix the hormonal disaster Crohn caused. Reducind estrogen to bring down DHT and up Testosterone to healthy levels is the first step (I am a 18 year old with low testosterone, I already tested myself).

If you really have low testosterone, that too, like Crohn's, is possible via small-vessel vasculitis , ( rather than a consequence of Crohn's ) ... http://www.ncbi.nlm.nih.gov/pubmed/18609261


( fake an illness?)

Faking anything is just going to muddy the waters and damage your relationship with your healthcare providers and health insurance, faking is a very bad idea.
The vascularity of my intestines  was normal after a colonoscopy study. Also, the most probable cause of my Crohns was heavy antibacterial medication when I was six years old after a Vesicoureteral reflux surgery( because Secondary vesicoureteral reflux is due to a urinary tract malfunction, often caused by infection.) promoting  bad bacteria proliferation and a violent immune response or that I have Celiac disease excacerbated by Nsaids. I used to have asthma though, around that age too, vasculitis can cause that. I have no pysical direct indications of vasculitis, and I can't afford testing vasculitis.
 

Offline RD

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18373 on: 25/06/2013 18:38:21 »
The vascularity of my intestines  was normal after a colonoscopy study

Crohn’s does not necessarily affect the colon , it can be confined the small intestine [it can be “ileal”]. Nor need active disease be permanently present.

... my Crohns ... I have Celiac disease

Celiac or Crohn’s is more likely to be true than Celiac+Crohn’s . There are blood tests to confirm Celiac …

Quote from: nih.gov
Celiac disease can be confused with irritable bowel syndrome, iron-deficiency anemia caused by menstrual blood loss, inflammatory bowel disease, diverticulitis, intestinal infections, and chronic fatigue syndrome. As a result, celiac disease has long been underdiagnosed or misdiagnosed. As doctors become more aware of the many varied symptoms of the disease and reliable blood tests become more available, diagnosis rates are increasing.

Blood Tests

People with celiac disease have higher than normal levels of certain autoantibodies—proteins that react against the body's own cells or tissues—in their blood. To diagnose celiac disease, doctors will test blood for high levels of anti-tissue transglutaminase antibodies (tTGA) or anti-endomysium antibodies (EMA). If test results are negative but celiac disease is still suspected, additional blood tests may be needed.

Before being tested, one should continue to eat a diet that includes foods with gluten, such as breads and pastas. If a person stops eating foods with gluten before being tested, the results may be negative for celiac disease even if the disease is present.
http://digestive.niddk.nih.gov/ddiseases/pubs/celiac/

There are also blood tests for vasculitis , e.g. ANCA test ...
Quote
p-ANCA with specificity to other antigens are associated with inflammatory bowel disease, rheumatoid arthritis, drug-induced vasculitis, autoimmune liver disease, drug induced syndromes and parasitic infections. Atypical ANCA is associated with drug-induced systemic vasculitis, inflammatory bowel disease and rheumatoid arthritis
http://en.wikipedia.org/wiki/Anti-neutrophil_cytoplasmic_antibody#Disease_associations

[NB:  ANCA-Negative vasculitis is possible ]

I have no pysical direct indications of vasculitis, and I can't afford testing vasculitis.

Free test #1: keep an eye out for "splinter haemorrhages" ...


http://www.hopkinsvasculitis.org/types-vasculitis/microscopic-polyangiitis/

Free test #2 : petechiae  https://en.wikipedia.org/wiki/Petechia

Free test #3: frothy urine can be caused by vasculitis ... http://en.wikipedia.org/wiki/Proteinuria
« Last Edit: 25/06/2013 19:14:36 by RD »
 

johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #18374 on: 25/06/2013 19:13:32 »
I have splinter hemorrhages. Not as much today but more some years ago.
 

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Re: Post Orgasmic Illness Syndrome (POIS)
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