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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6451636 times)

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19500 on: 06/04/2014 14:24:06 »
To all TRTers .. have you experienced any minor/major side effects ?
 

Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19501 on: 06/04/2014 14:50:47 »
To all TRTers .. have you experienced any minor/major side effects ?
Increased stress levels during the warmer months of the year but less so during the cooler months. More assertiveness & confidence & libido & strength then (mid autumn - mid spring). Some hair loss. Fat loss - all over including face. No acne but skin a little oilier. No roid rage, but sometimes higher frustration/irritation over annoyances - but I would not really call this a side effect as it had no negative issues for me. When I was was on 1 a month injection it see-sawed my libido - start of the month I was very horny (more Os but quicker recovery), near the end of the month - poor libido + erections issues (by the end of the month the injected T had worn off and my own natural T was suppressed due to the higher levels at start of month signalling my body to lower production + also probably higher estrogen levels relating to the spike in T earlier in the month. My testicles would feel cold at the end of the month and pois was definitely worse. Stable levels are totally the way to go.
Before I went on TRT, I had suffered from dandruff (linked to pois somewhat) and this disappeared (great!) Also my levels of anxiousness & self consciousness (linked to pois) reduced, but really only when I went up to the higher levels.
« Last Edit: 06/04/2014 14:54:15 by acronym »
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19502 on: 06/04/2014 16:10:41 »
Personal ancedotes: TRT has cured my POIS.
......

FD, that's a pretty high dosage of T. Is your doctor prescribing you this amount or are you undertaking this on your own?
the cypionate ester if I remember right has a short half life, so you will need more frequent injections,but that is still a high dose, from a 'conventional' medical perspective. I am on Testosterone Ethanate (longer half life) and am currently at 100mg a week, which is higher than what my doctor wanted, but I feel better for it and have never scored high on T blood tests (with just T injections).

When I was originally put on T shots it was a once a month injection, and that screwed me up - way too much fluctuation, and my pois got worse. I split my doses up and increased the amount I was taking and I was a lot better for it. I did this then told my doctor and he reluctantly went along with it. The official doctors drug manual for Sustan250 for instance still recommends once a month injection. I found I was struggling by day 18 and when I had blood tests on say around day 10-12, my levels were at 1/4 of the normal range.  I have experimented with T by taking high doses at your levels and had mixed results. In the cooler months of the year I felt better for it and put on weight and my pois was less. In the warmer months of the year it seemed to make no difference. I had increased stress levels & more hair loss though. Its weird and very very frustrating. The only time I put on weight is in the cooler months. I still lose weight in the summer even during the times I was on 100mg+/week.

I took an OTC anti aromatase + also herbs. I did not experience any gyno, but some people are less susceptible. I have low body fat levels.  When I trialled 200mg/week, I took Clomid when I dropped my T intake back to lower levels, and I cant say I noticed anything, but then I did not crash so it could have been doing its job well. I did not get any T blood tests to verify my levels at this time.

I had good results with the herb TongkatAli which boosts LH ( and maybe also FSH levels) and testosterone a number of years ago. I have since tried it a few more times but have been disappointed. This is a potent herb and grown only in limited part of the word and there is a lot of bogus/weak product out there now being marketed. I feel this would be a good herb for some pois'ers to try. Unfortunately I cannot recommended a good source. It very expensive now too. I have asked a couple of my doctors about trying Clomid or Pregnyl to increase my natural T levels but they are not interested.

I also experimented by taking Nandrolone as well as Testosterone (lower dose - 60mg/week) and found taking the two together to be more potent at the equivalent dose of just testosterone. (blood test for T levels showed me at the top end of normal for the first time in my life) My pois was much better too, however like the comment I made earlier about T being more beneficial for me during the cooler months, it is the same story when I take T & N, alas.  My pois has always been less in the cooler months even before I took any supplements. I can't remember anyone else here saying there was a seasonal component to pois. Around the same time I got pois I got chemical sensitivities + food intolerances. I tested at very high on IgE levels (related to allergies) and strong reaction to many grasses (even though I don't get hayfever anymore - that stopped when I got pois). I wonder if the grasses which are high except in the cooler months are impacting badly on my immunity/endocrine system...even though I don't have hayfever.

I cannot comment on pois in relation to my IGF-1 levels, as I have never had a good IGF-1 reading. I have below normal IGF-1. Same with DHEA.  There certainly could be a connection though.

Is your doctor prescribing you this amount or are you undertaking this on your own?  More like 50/50, the problem is, there is a depopulation and anti male agenda, and if I lower my dose and it does not work anymore I will get a hard time getting to the place I used to be. Besides, I am not experiencing side effects. Test cypionate has a 8 day half life I believe.

I think I read somewhere that low DHEA is an indicator of high cortisol and high cortisol would explain the low IGF- 1. I also read that increasing DHEA would suppress cortisol, which is why I experimented with DHEA supplements. You can also try HGH(human grwoth hormone) which will solve the IGF1 issue and will add some extra benefits like increased dose dependent collagen synthesis including other anti aging benefits. But there is a witch hunt againt HGH sadly which makes it hard to get (plus it is expensive as F...) Circulating IGF-1 is generated by the liver under the control of growth hormone (GH). The binding of GH with its hepatic receptor stimulates expression and release of IGF-1 peptide in the circulation, which has high affinity for IGFBPs, and represents the endocrine form of IGF-1
but that thing is very useful to the point that it would have regenerated my ulcerated intestines in weeks. IGF-1 is EXTREMELY IMPORTANT ,IGF-1 supports cellular division and growth to the muscles and organs among other things, you have to fix that quick.


 IGF-1– can induce reduction in oxidative stress, cell apoptosis, proinflammatory signaling, and endothelial dysfunction. Aging is associated with increased vascular oxidative stress and vascular disease, suggesting that IGF-1 may exert salutary effects on vascular aging processes.

Hypertension is a major risk factor for atherosclerosis, and aging influences the prevalence of hypertension, whereas aging by itself appears insufficient to induce hypertension (168,169). As described above, IGF-1 increases endothelial NO production; hence, a major part of IGF-1 effects on vascular tone regulation can be attributed to eNOS–NO dependent mechanisms. In addition, insulin/IGF-1 reduces [Ca2+]i and Ca2+-MLC sensitivity in VSMC (170,171), thereby inducing vascular relaxation.

http://biomedgerontology.oxfordjournals.org/content/67A/6/626.full

If you are interested I will post more studies later .
« Last Edit: 06/04/2014 16:42:38 by fornicationDENIED2 »
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19503 on: 06/04/2014 16:31:19 »
To all TRTers .. have you experienced any minor/major side effects ?

Well, the problem whit testosterone is that there is alot of misinformation particularly the fear mongering from the media.

I know what you truly are concerned about hahahaha, and the answer is no, TRT will not decrease the size of your ... how do I put this without getting banned... gentleman's sausage. I have personally experienced an increase in 0.5 inches in length and more girth but not enough to live my POIS free life as a pornstar sadly.
 

Offline meteo74

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19504 on: 06/04/2014 18:03:48 »
Hi everyone,

I found this thread after realizing I had POIS. It was getting worse for me over time and now that I have a girlfriend my symptoms were really showing up.

I would feel tired/achy/grumpy for a day or two after sleeping with her, and the more we slept together the worse it got. It felt like a hangover from a really bad night of drinking.

I tried taking more vitamins, changing my sleep/exercise routines/, not watching porn anymore, etc., which all helped but never solved the problem.

Finally what worked for me was getting off of gluten. My POIS that I've had for many years vanished!

I just wanted to log in and share my experience in case it helps anybody searching for an answer. I know I got to the point where I was willing to try anything that might have helped, so here's another thing to try.

Good luck to everyone.

Sincerely,
Seth


hi sethlessness
what does gluten mean,i look for it in google translation but can't understand ,would you say some,and how many years were you in pois..
thank.
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19505 on: 07/04/2014 02:21:23 »
What Testosterone dosage do you take TRTers ?
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19506 on: 08/04/2014 12:05:00 »
I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19507 on: 09/04/2014 12:00:14 »
Hello to all of you,

I've been investigated the gluten lead recently and I think there is something :

-First of all, there is different testimony of people flaming that there are pretty much POIS free since they eliminate the gluten from their diet

http://poiscenter.com/forums/index.php?topic=1240.0

http://poiscenter.com/forums/index.php?topic=387.msg10629#msg10629


Seth recently :

http://www.thenakedscientists.com/forum/index.php?topic=6576.19475

-Some people have been diagnosed with gluten allergy(kurtosis, urano, etc)

-If you read about gluten intolerance/sensitivity, you find out that there is tons of potential symptoms ; it's due to the fact that (i) gluten triggers autoimmune reaction with the typical symptoms of it and that it can cause malabsorption and deficiency(of amino acid/vitamins/minerals) that lead to various symptoms and can explain the fatigue and the cognitive impairments.

-One the promising "cure" some year ago was multivitamin program ; helped a lot ; It's not surprising if we have deficiency and potentially lead to digestion problem.

-Some people I've talked with doesn't get weight easily and I'have read in POIS forum that they have greasy/sticky faeces and digestion problem : it's typical if gluten intolerance is involved ; we don't digest fat.

I believe that Orgasm/sexual activity just trigger/worsen an underlining problem ; It's maybe a mistake to focus on O.

Nevertheless, there is a link between potentially digestion and Orgasm...and this could be the Vagus nerve(object of the ongoing POIS research).

Personally I will verify that lead and going to a strict non gluten diet for at least 2 month

good luck fellow poiser's
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19508 on: 09/04/2014 12:25:41 »
That is interesting too ; the part I like the most is :

"interesting fact that her problems were not constant, indicating that basically her brain was intact but something seemed to be detrimentally influencing her from time to time, causing her to have these significant issues with respect to how her brain functioned. In considering what factors change day to day in terms of someone's exposure, certainly diet is at the top of the list"

http://www.huffingtonpost.com/dr-david-perlmutter-md/gluten-impacts-the-brain_b_785901.html
 

Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19509 on: 09/04/2014 15:36:47 »
LAPOISSE2

I fully agree with you!
 

Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19510 on: 09/04/2014 15:42:46 »
vagus nerve

Treatment. Analgesics for pain relief used in combination with antihistamines, anesthetics (0.5% novocaine solution intravenously), B vitamins (cyanocobalamin - 1000 mcg and thiamine chloride - 1 ml of 0.5% solution intramuscularly every other day). Of physiotherapy appointment effectively diadynamic currents pain radiating portion. 

Treatment. B vitamins, stimulants, neostigmine (0.015 g), atropine (1 ml of 0.1% solution subcutaneously). When the etiology of diphtheria - large doses of diphtheria serum

Maybe that's why vitamins helps people?
 

Offline Kima

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19511 on: 09/04/2014 15:46:30 »
Pois syndrome are very similar to nerve disease . Likely sperm touches a nerve and so we get these symptoms
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19512 on: 09/04/2014 17:12:42 »
Sounds possible kima.
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19513 on: 09/04/2014 23:39:00 »
I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?
I would not take Finasteride if I was you because DHT is not exactly as dangerous and destructive as estrogen can be . First you must get a blood test (a couple of days after injection, but I would wait around 3 weeks of treatment before testing, also do not test yourself at the testosterone peak which is around the 2 or 3 day but on the 4th or 5 day)  to see if DHT is outside the range , and or experience detrimental DHT side effects, then take it. Finasteride side effects include impotence, loss of sex drive(obviously caused by low DHT, can't prove if you are POIS free if that happens hahaha), it could (not guaranteed)  also cause anxiety and depression.
 Anastrozole binds reversibly to the aromatase enzyme through competitive inhibition, meaning once daily makes sense but if you need to lower dosage try a formula like 0.5mg daily, since this drug has short lasting effects and keep in mind your estrogen cant be zero or extremely low, since it can cause fatigue and other side effects.
« Last Edit: 09/04/2014 23:55:55 by fornicationDENIED2 »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19514 on: 10/04/2014 01:10:28 »

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?


[Former Moderator visiting periodically]

I recommend to anyone contemplating TRT for your POIS: discuss infertility risks carefully with your doctor!!!!

« Last Edit: 10/04/2014 03:54:59 by demografx »
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19515 on: 10/04/2014 05:45:29 »

I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?




[Former Moderator visiting periodically]

I recommend to anyone contemplating TRT for your POIS: discuss infertility risks carefully with your doctor!!!!


Ive discussed this with my doctor. He says that injecting sustanone 250 till 6 weeks will bring sperm count to zero ( ie azoospermia ) and then if I stop taking injections sperm count would recover within 9 months.

I am still 18 so do not have to produce kids. So no worry.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19516 on: 10/04/2014 05:55:04 »
[Former Moderator visiting periodically]

Excellent! :)

« Last Edit: 10/04/2014 05:57:55 by demografx »
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19517 on: 11/04/2014 09:18:23 »
Hi everyone,

I found this thread after realizing I had POIS. It was getting worse for me over time and now that I have a girlfriend my symptoms were really showing up.

I would feel tired/achy/grumpy for a day or two after sleeping with her, and the more we slept together the worse it got. It felt like a hangover from a really bad night of drinking.

I tried taking more vitamins, changing my sleep/exercise routines/, not watching porn anymore, etc., which all helped but never solved the problem.

Finally what worked for me was getting off of gluten. My POIS that I've had for many years vanished!

I just wanted to log in and share my experience in case it helps anybody searching for an answer. I know I got to the point where I was willing to try anything that might have helped, so here's another thing to try.

Good luck to everyone.

Sincerely,
Seth

Hey All,

Nobody care about that ? We're all desperately trying to find a cure, someone show up saying that eliminating something from its regimen(not a big deal) kinda cured him and nobody make attention to it..
I know we've had many "magic cure" but believe me there is many other case and malabosption induce disease is not like breathing with right nostril or swallowing some magic  chinese herb...All the guys that talked about gluten problem in here never came back ; As we said in France, No news : good news

It just makes a lot of sense, digestion is the entrance door of our complete health...what you put in your mouth make you healthy or not.We are all looking for a root cause of our problem, this could be one.If your deficient is minerals or vitamins, all the system is screwed and orgasm could just be the spark. Gluten can be the root cause of many disease, POIS could be of them

Please guys, react to this, don't be blind...there is no certitude at all, but it definitely worth to investigate.

And if you have time, read about what is gluten intolerance

This is one of many article about it :

http://www.mindbodygreen.com/0-7482/10-signs-youre-gluten-intolerant.html`

By the way, do we any chinese or japanese here ? Saw 1 chinese in 3 years of looking at the forums...Why ? Maybe because they have no gluten at all in their diet
« Last Edit: 11/04/2014 10:18:12 by LAPOISSE2 »
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19518 on: 11/04/2014 09:31:40 »
This one also is ver very interesting :

http://chriskresser.com/50-shades-of-gluten-intolerance
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19519 on: 14/04/2014 00:12:53 »
hi guys,
Although I do not have POIS, I think that I may be able to throw some light on where to focus or investigate to track down the source of the problem.
Actually, I have the symptoms of POIS all the time, and always have had, which is why I found this forum.
But my symptoms are caused by life-long bilateral tumours of my adrenal glands, also known as pheochromocytoma (PCC), usually benign, but which release large quantities of adrenaline (epinephrine) into the bloodstream, either continuously or intermittently.
This is all very new to me too, and not fully-confirmed because I am still working through the full suite of tests and imaging studies for PCC. Initial imaging studies show a tumour within each adrenal gland and I have all the classic symptoms of PCC.
Its a pretty rare condition and one autopsy study found that 75% of patients die without being diagnosed - usually having been labelled "crazy".
It seems quite plausible to me that sexual arousal, activity and orgasm is triggering the release of a large adrenaline hit and causing POIS in susceptible men.
Do any of you guys have secreting adrenal tumours? Probably not, but I would suggest that the adrenal glands are at the pathophysiological centre of POIS whatever the actual pathological mechanism.
I read that some of you guys have had lots of standard blood tests, including hormonal ones too, like testosterone. But, unless you specifically have an endocrinologist, who actually suspects PCC, it is highly unlikely that you have had the blood and urine tests which will link POIS to the adrenal glands. Very often, even in PCC patients, the blood testing does not pick it up for various reasons, so the blood tests are backed up with 24 hour adrenaline in urine testing. Anyone on here done the latter?
Excessive adrenaline release really messes around with your blood pressure and heart rate for quite a long time afterwards so these physical correlates could offer some objective evidence for POIS. It messes with your brain too, as you know from experience, but that is more subjective.
Has anyone with POIS been regularly using a personal blood pressure and heart rate monitor? I would highly advise every POIS patient to buy an automatic one (battery-operated) not a manual one. They are available very cheaply everywhere. I use a wrist-mounted one rather than upper arm which are a lot smaller and less cumbersome to use. Most have a memory for around 60 to 100 readings. Just remember that when you take a reading with a wrist monitor your wrist must be on the same level as your heart. All the information that you need on this post will be found in the monitor instruction manual.
I would start by taking blood pressure readings when you are feeling well ie. after a week or two without sexual activity. Take two readings at rest - one after you have been lying horizontal for 5 minutes or more and then stand up and immediately take another reading and repeat this through the day. If you are well, then both your readings should be in normal range as advised on the monitor. When you stand up, you should get a similar blood pressure or maybe a lower one to the horizontal, but definitely not a higher one (ie. orthostatic hypertension).
Then, after orgasm, start taking regular readings when horizontal and immediately after standing up. Remember to keep your wrist at heart level when reading standing up.
Does your blood pressure remain in normal range after orgasm? Only when horizontal? Only when vertical? Or both? If your blood pressure increases after standing up then that is a red flag for excess adrenaline release.
Keep an eye on your heart rate during the readings too - is the monitor alerting any heart rate increases above normal?
Make a note of any headaches against the readings - rate the severity of the headaches. You might even have a continuous low-level headache during the days after orgasm?
Write down the dates and times of the blood pressure/heart readings from the monitor memory on to a calendar - is there a pattern over the days after orgasm? Anything noteworthy?
Ultimately, is there a similar pattern found in all POIS patients?
Well, I really hope you guys find this post useful. I am as interested in POIS as you are.
I will stay on the forum and reply to any responses - or any private emails.
It would be really fascinating to generate some medical data on POIS with this approach.
regards
gpg
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19520 on: 14/04/2014 11:06:27 »
hi guys,
Although I do not have POIS, I think that I may be able to throw some light on where to focus or investigate to track down the source of the problem.
Actually, I have the symptoms of POIS all the time, and always have had, which is why I found this forum.
But my symptoms are caused by life-long bilateral tumours of my adrenal glands, also known as pheochromocytoma (PCC), usually benign, but which release large quantities of adrenaline (epinephrine) into the bloodstream, either continuously or intermittently.
This is all very new to me too, and not fully-confirmed because I am still working through the full suite of tests and imaging studies for PCC. Initial imaging studies show a tumour within each adrenal gland and I have all the classic symptoms of PCC.
Its a pretty rare condition and one autopsy study found that 75% of patients die without being diagnosed - usually having been labelled "crazy".
It seems quite plausible to me that sexual arousal, activity and orgasm is triggering the release of a large adrenaline hit and causing POIS in susceptible men.
Do any of you guys have secreting adrenal tumours? Probably not, but I would suggest that the adrenal glands are at the pathophysiological centre of POIS whatever the actual pathological mechanism.
I read that some of you guys have had lots of standard blood tests, including hormonal ones too, like testosterone. But, unless you specifically have an endocrinologist, who actually suspects PCC, it is highly unlikely that you have had the blood and urine tests which will link POIS to the adrenal glands. Very often, even in PCC patients, the blood testing does not pick it up for various reasons, so the blood tests are backed up with 24 hour adrenaline in urine testing. Anyone on here done the latter?
Excessive adrenaline release really messes around with your blood pressure and heart rate for quite a long time afterwards so these physical correlates could offer some objective evidence for POIS. It messes with your brain too, as you know from experience, but that is more subjective.
Has anyone with POIS been regularly using a personal blood pressure and heart rate monitor? I would highly advise every POIS patient to buy an automatic one (battery-operated) not a manual one. They are available very cheaply everywhere. I use a wrist-mounted one rather than upper arm which are a lot smaller and less cumbersome to use. Most have a memory for around 60 to 100 readings. Just remember that when you take a reading with a wrist monitor your wrist must be on the same level as your heart. All the information that you need on this post will be found in the monitor instruction manual.
I would start by taking blood pressure readings when you are feeling well ie. after a week or two without sexual activity. Take two readings at rest - one after you have been lying horizontal for 5 minutes or more and then stand up and immediately take another reading and repeat this through the day. If you are well, then both your readings should be in normal range as advised on the monitor. When you stand up, you should get a similar blood pressure or maybe a lower one to the horizontal, but definitely not a higher one (ie. orthostatic hypertension).
Then, after orgasm, start taking regular readings when horizontal and immediately after standing up. Remember to keep your wrist at heart level when reading standing up.
Does your blood pressure remain in normal range after orgasm? Only when horizontal? Only when vertical? Or both? If your blood pressure increases after standing up then that is a red flag for excess adrenaline release.
Keep an eye on your heart rate during the readings too - is the monitor alerting any heart rate increases above normal?
Make a note of any headaches against the readings - rate the severity of the headaches. You might even have a continuous low-level headache during the days after orgasm?
Write down the dates and times of the blood pressure/heart readings from the monitor memory on to a calendar - is there a pattern over the days after orgasm? Anything noteworthy?
Ultimately, is there a similar pattern found in all POIS patients?
Well, I really hope you guys find this post useful. I am as interested in POIS as you are.
I will stay on the forum and reply to any responses - or any private emails.
It would be really fascinating to generate some medical data on POIS with this approach.
regards
gpg

Hey, My doc thought I had these to because I was doing a bit of tachicardia ; I've tested my BP for a month and tested the blood and urine catecholamines and all was pretty normal..
 

Offline acronym

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19521 on: 14/04/2014 12:10:43 »
gpg - thanks for that interesting post.
Q - Did having an orgasm make any difference for you, having PCC (I would have thought it would have)?
Q - Were you underweight and had great difficulty putting on weight?
Q - Did you have headaches most days of the week?
Q - Were you up and down between 'wired & anxious' and 'exhausted & brain foggy'?

I have never had high BP. In fact I was on the low side for many years and normal blood glucose levels, and lack of sweating as opposed to excessive sweating, but ticked the other symptoms. cheers
« Last Edit: 14/04/2014 12:15:20 by acronym »
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19522 on: 14/04/2014 12:56:18 »
Do Poisers feel symptoms in summer ?
 

Offline Colmik

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19523 on: 14/04/2014 16:31:29 »
After the vast amount of information given in this thread, I don't suppose this post will be of any value, but I'll throw it into the ring in case it sparks an idea ion somebody's mind.

I had a PSA test a few months ago.  PSA = Prostate Specific Antigen - an indicator for prostate cancer.
My count was 3.8, which was said to be safe for my age (less than 4.0), but I was still a bit concerned, as my previous count, a couple of years ago, was 2.0.   I was told that the reading is most reliable if it is not taken within three days of an orgasm.

So it seems that it takes several days for PSA levels to settle down.  Could that be connected with the subject of this thread?

Oh, well, I said it probably wasn't important!
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19524 on: 15/04/2014 00:19:20 »
gpg - thanks for that interesting post.
Q - Did having an orgasm make any difference for you, having PCC (I would have thought it would have)?
Q - Were you underweight and had great difficulty putting on weight?
Q - Did you have headaches most days of the week?
Q - Were you up and down between 'wired & anxious' and 'exhausted & brain foggy'?

I have never had high BP. In fact I was on the low side for many years and normal blood glucose levels, and lack of sweating as opposed to excessive sweating, but ticked the other symptoms. cheers

hi acronym and lapoisse2
I will start by answering acronyms questions. (PCC is pheochromocytoma adrenal gland tumour).
A - Yes your thought is correct - I assumed the question of my orgasm would be first. Firstly, my orgasm is a phenomenally heightened experience - I am presuming much more so than normal. Obviously, I did not realise this until very recently - I presumed everyone felt like they got hit with a sledgehammer. A powerful initial sensation but not being put physically/mentally out of action for an extended period of time like you guys - because my health is like that all the time, even before the orgasm.
I would think that a small amount of adrenaline release during orgasm is normal but not a large, excessive, release, which is what I think is happening, in isolation, in PIOS - rather than the continuous excess of PCC.
However, as you all describe, there is no choice about whether to have a regular orgasm or not because the sensation of continually craving an orgasm is unbearable. This is why I am locked into this cycle too. I think this whole scenario has something to do with adrenaline de-sensitisation of the cell receptors due to the regularly occurring excess adrenaline. Our cells crave the adrenaline due to their adrenaline de-sensitisation but that additional release from orgasm just makes everything else worse afterwards - or in my case, the same as always. De-sensitisation of cell adrenaline receptors is a proven phenomenon in PCC.
A - Yes - I am underweight for my height because I do have difficulty putting on weight. Apparently, this is due to the adrenaline speeding up the metabolism and burning off food intake too quickly. I have to eat four high calorie meals per day just to remain underweight and that is without doing any exertion or exercise.
A - Yes - I have had a continuous low level headache since before I can remember but I am only understanding this now. Then, in the past year, I have started having regular adrenal crisis where headache pain is unbearable and  horrific. This lasts for around 2 hours and my blood pressure goes up to 150 with hot sweating flushes.
A - That last question describes my brain scenario exactly. Years ago, I once said to the doctor that my brain is either "racing" with unstoppable thoughts or completely "dead" to all thought - there was no normal balance. I really believed that this would give the doctor some obvious clue to what disease I had. But, of course, when you say something like this, you come across as a manic-depressive or having a somatic disorder ie, either way just crazy. I think the racing thought is the effect of the initial excess adrenaline release and the dead brain is the adrenaline hogging the cell receptors for an extended time, in place of other brain chemicals needed for normal brain function.

I was also told that I had low BP for years. But BP is always taken at rest sitting down - never after rising to a standing position - where raised BP against lying horizontal is the tell-tale sign.
Also, when was your BP taken in relation to the timing of your orgasm - BP may only be higher in the hours and days following orgasm?

This brings me to Lalpoisse2 comments that he has had 24 hour urine testing for catecholamines (adrenalines).  Was this done by an endocrinologist or your family doctor request? Was this done in the 24 hours after orgasm? This urine test is based on PCC where urine levels are usually high on any day. And, PIOS is not PCC. It will have its own pathology. No one currently knows the best way or time to detect the adrenaline release in PIOS. Even in PPC, it can take a dogged endocrinologist to persevere and get the testing right, especially if tests are initially coming back negative for various reasons. And, if you do not already have demonstrated tumours on imaging, most doctors will accept those false negative results because it is difficult to justify continued testing on a hunch, particularly when you are saying that you have PIOS.

Sweating is another interesting one because inappropriate sweating is one of the so-called diagnostic triad of PCC signs during an adrenal crisis - the others being unbearable headache (requiring morphine) and high BP. Yet sweating is the most variable sign among PCC patients.
Before a year ago, I also did very little sweating but now I get random bouts of hot flushes and sweating for no reason (inappropriately). However, I have always sweated inappropriately during very minor bouts of physical exertion - which also comes with feeling very unwell. So, you need to think about when and how you start to sweat. It is more like an inappropriate pattern of sweating behaviour, I think. Its not about normal appropriate sweating but the sign of your body sweating due to excess adrenaline - so for PCC patients that means during minor exertion, or an adrenal crisis, or during hot weather (which PCC patients avoid).

Thank you for the interesting questions - I hope I have answered them relevantly.

regards
gpg
 

The Naked Scientists Forum

Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19524 on: 15/04/2014 00:19:20 »

 

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