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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6444807 times)

Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19525 on: 15/04/2014 09:12:45 »
do any of u have difficulty/pain having hot tea,cofee,hot soup etc after orgasm? i have developed this problem too
 

Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19526 on: 15/04/2014 14:59:58 »
And yes i have normally high bp 160 and above since childhood and bad sweat and  mental problems like racing thoughts and dull brain from last 2 years
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19527 on: 15/04/2014 17:09:38 »
And yes i have normally high bp 160 and above since childhood and bad sweat and  mental problems like racing thoughts and dull brain from last 2 years
hi gondal
In your case, being ill since childhood, you must get a CT or MRI scan of your adrenal glands to check for pheochromocytoma (PCC). There are specific adrenal gland scan protocols which find them.
I dont know where you live but I would pay for one if you can afford it - like I did - rather than trying to convince your health system to pay for one - its a lot less stressful.
If the scans find tumours in your adrenal glands then you will then get the blood/urine and heart testing that you need because you are PCC symptomatic.
Good luck - let us know.
gpg
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19528 on: 16/04/2014 00:42:32 »
[Former Moderator visiting periodically]


I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?


Periodic ingestion of testosterone did NOT work for me.

In my case I started with injectable testosterone: it didn't work (for me)

According to my endocrinologist, DAILY testosterone patches -- or testosterone gel -- are the way to go for me. Why? His expert opinion is that daily patches or gel best mimic the natural way that testosterone courses through our body. Periodics -- such as injectables -- run counter to the natural method in that they "spike" in and out of our systems, summarizing for you what my endo said to me.

« Last Edit: 16/04/2014 00:47:22 by demografx »
 

Offline MrVat7

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19529 on: 16/04/2014 07:27:26 »
[Former Moderator visiting periodically]


I am starting TRT .
Dosage- 250mg Sustanone once a week. anastrazole 1mg daily,and  tablet Finasteride 1 mg daily.

Any expert advice or suggestion guys ?


Periodic ingestion of testosterone did NOT work for me.

In my case I started with injectable testosterone: it didn't work (for me)

According to my endocrinologist, DAILY testosterone patches -- or testosterone gel -- are the way to go for me. Why? His expert opinion is that daily patches or gel best mimic the natural way that testosterone courses through our body. Periodics -- such as injectables -- run counter to the natural method in that they "spike" in and out of our systems, summarizing for you what my endo said to me.



Yes but taking testosterone patches or Tgels increase the chance of side effect such as gynecomastia.. as more of aromatase enzyme are located near muscle and fat cells .. my andrologist said that sustanone 250 has long half life esters.. and it should be injected deep inside.. so less chances of having side effects.. and i dont know why injectables didnt worked for you .. what dosage were you taking ? and which ester ?
 

Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19530 on: 16/04/2014 08:59:45 »
I have tried testosterone patches for over 4 years-no difference.

I have tried a diary and gluten free diet for a very long time also-no difference.
 

Offline Jonas STHLM

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19531 on: 16/04/2014 09:08:35 »
I like to come in contact with other poisers in Sweden so the rest of my message will be in Swedish.

Hej allihopa, jag har varit i kontakt med Stefan Arver som är docent och överläkare på karolinska sjukhuset och specialiserad på andrologi och sexualmedicin. Han kommer att ta kontakt med Waldinger, men även de forskarna på Rutgers universitet som skall genomföra forskningen på vårat problem. Han är intresserad av att hitta en lösning och jag tror att det kan vara en bra ide att höra av sig till honom, ju mer vi är desto större är chansen att vi får hjälp även på hemmaplan. Kontakta mig för hans mejladress.

Tack för hjälpen,

Jonas
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19532 on: 16/04/2014 10:35:54 »
hi guys
The adrenal glands also secrete the sex hormones. Although the adrenal glands are not the primary site of sex hormone secretion, if there is a problem with the adrenal glands and periodic excess adrenaline secretion, then this will mess with your sex hormones.
In this situation, the sex hormones are a symptom of POIS, not the cause. Treating sex hormone symptoms may or may not lead to improvement of POIS. The central issue of excess adrenaline release is not being addressed.
Although the initial hit of excess adrenaline release occurs just after orgasm and is rapidly cleared from the bloodstream, it is the extended length of time that adrenaline remains docked in the cell receptors of just about every cell in the body that would explain the "post" in POIS. The functioning of those cells is disrupted and messes up all the normal hormone levels.
This appears to be the reason that sustained-release testosterone patches are the most effective because the
release needs to be continuous to ameliorate the sustained effects of the initial excess adrenaline release.
regards
gpg
 

Offline Scarysheep

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19533 on: 17/04/2014 02:23:27 »
Hello, everybody. I found this forum a few months ago, but have only now decided to post.

I figure I better introduce myself first:
    My symptoms include: Fatigue, sleepiness- even with over 12 hours of sleep, joint/muscle pain, general discomfort, dry lips/hands, irritability, loss of social skills, loss of concentration and ability to recall a passage after I've read it, shakiness, sticky/sandy feeling eyes, shallow breathing and constant feeling of coldness.
    My symptoms start immediately after orgasm and grow in intensity over days one and two, and remain constant through day five. On day 6, they taper off throughout the day and by nighttime on day 6, I feel wonderful. It takes about 12 days to recover entirely.
    I am 17 years old and have had these symptoms as long as I can remember and they are absolutely debilitating. I've had several blood tests done, none of which yielded meaningful results except a high-ish prolactin level, which I've been taking wellbutin for 3 days now with no relief of symptoms yet, though from what I've read hear, I'm not optimistic. I take 250 mg flush Niacin daily before bed, which takes the edge off the shakiness and weird eye feeling, but at the cost of drymouth. The unpredictability of nocturnal emissions is the bane of my existence and has equal effect as intentional orgasm (which I've pretty much given up entirely).
    Things I've noticed: When I take niacin while feeling pois, the flush does not cover entirely like normal, its patchy, as if the blood flow is not as it normal is. I've been experimenting with gluten-free for the last 3 days; no conclusive results yet, but I almost feel an improvement already. I'll continue experimenting with this for a few more days or weeks, depending on improvement. My sitting blood pressure is normal, but (at least at the doctor's office), my standing blood pressure was high.
    Interesting note: I measure my pois days by how well I can play my trombone. The bad days, I can barely play well, but on good days, I'm amazing- like got one of the top scholarship spots for my state's best music school good. I want to be able to pursue a career in music, but this condition is so bad it may end up ruining me.

That's pretty much all I've got. Please feel free to ask me questions or for specifics and I'll try to get back to you! I truly believe we can get to the bottom of this medical mystery. If there's anything you recommend I try please to not hesitate to suggest it.

hi guys
...etc.
gpg
Also, Mr. gpg, how would you recommend I start looking into your adrenaline based solution, since I have some blood pressure issues and you seem to have a good lead here?
« Last Edit: 17/04/2014 02:39:45 by Scarysheep »
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19534 on: 17/04/2014 12:36:08 »
hi ScarySheep
Once again, you have had these problems since childhood, and you are only 17, so you definitely need to get an MRI scan of you abdomen, looking for adrenal gland tumours. It is essential that you rule this out (or in), including other vital organ issues which could be picked up, otherwise you could waste many years of your life without knowing for sure.
Getting a single area (abdomen)  MRI scan privately is pretty straight-forward and not too expensive - plus many places do not ask for a doctors referral - you can self refer. A CT scan is more difficult because it uses x-ray radiation and most private imaging companies will request a doctors referral to justify this. Also, you need a special type of CT scan but only a standard MRI to pick up any tumours. So, if you are self referring, an MRI is the best way to go.
Once again, your blood pressure is increasing when you stand up (orthostatic hypertension), and that is a red flag for the existence of adrenal gland dysfunction and/or PCC tumour.
Ask your doctor how he is going to investigate your orthostatic hypertension. Your doctor found this himself so he can not dismiss it.
Tell him that you would like an MRI scan of your adrenal glands either through him - if refused go privately. Have the scan done immediately - no matter what other action is taken.
Tell him that you are experiencing symptoms consistent with excess adrenaline release and that you would like to be referred to an endocrinologist.
The reason that you are able to feel much better periodically is because the adrenaline is finally letting go of the cell receptors that it is hogging on every cell in your body. Once those receptors are cleared then you feel "normal" again.
Let us know.
good luck
gpg
 

Offline fornicationDENIED2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19535 on: 27/04/2014 21:56:49 »
I have increased the frequency of ejaculation and noticed the war is not over. I am still having hyperprolactemia (caused by the prednisone induced cushing's syndrome) is still causing issues, I was initially denied treatment despite having the prolactin levels of a woman because I was still inside the stupid range because apparently doctors are either too dumb to realize that despite being inside the range a real man should NOT have prolactin that high, or avoiding a possible lawsuit at my expense by denying treatment. I now have to make the decision to masturbate before my next prolactin test, or be honest and live with this curse till I die because of absurd antiquated protocols, not a hard choice to make if health and fornication is on the line. Keep in mind I have tried everything else in my reach to try to reduce prolactin without dopamine agonists yet failed miserably. I was hoping to avoid those dopamine agonists drugs because of their side effects but it seems I have no other choice.

If you have a 24 to 48 hours or more refractory period if you cant have an erection despite being young and healthy I advice getting prolactin levels checked.
« Last Edit: 27/04/2014 22:02:07 by fornicationDENIED2 »
 

Offline Thapelo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19536 on: 03/05/2014 12:13:28 »
Do Poisers feel symptoms in summer ?


I do not MrVat7, at least it is significantly less than in the winter.
Especially feeling depressed/down is reduced in the summer compared with the winter

 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19537 on: 11/05/2014 16:03:01 »
poiscenter.com seems to be down. When I try to access it I just get this message:

"Notice: This domain name expired on 05/09/14 and is pending renewal or deletion".

Anyone else getting this also? This is very worrying to me.
 

johanstefansson

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19538 on: 11/05/2014 19:01:15 »
having had tinnitus for quite some time, 17 years, I today read about levels of adrenalin, how tinnitus increases levels of adrenalin.

also said sex creates spikes in adrenalin.

your thoughts about this?
 

Offline Vincent M

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19539 on: 11/05/2014 23:11:11 »
Nevermind. Seems to be back up now. Odd.
 

Offline gpg

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19540 on: 14/05/2014 23:55:34 »

hi Scott

This is a reply to your private email to me which I have no way to reply to. The reply is quite general so I hope it might be of interest to other POIS patients.

Thank you for your comments on my posts.

First of all, I am not saying that you guys or girls ALL have a pheochromocytoma (PCC) in your adrenal glands - I am just pointing out a major overlap of adrenaline related symptoms between PCC and POIS.

Maybe all of the small percentage of women with POIS do actually have a PCC and POIS is actually a totally male disorder?

I think that POIS is an adrenal gland disorder - but what type? Male hormones are part of it but
maybe not female hormones, making it a male disorder?

I think that an MRI of the adrenal glands is the best place to start - firstly to rule out/in
PCC and secondly to check for any kind of tissue mass in the adrenal glands which
should not be there.

These non-PCC adrenal masses are usually labelled as incidentalomas by the docs but if you
have POIS then these anomolous tissue masses could be anything but incidental.

I would not be surprised if all POIS patients have some kind of pathological tissue mass in their
adrenal glands - either PCC or something functionally similar.

If any type of mass is found in the adrenal glands then you have a physical focus for your adrenaline
symptoms and hopefully adrenal functioning testing will elucidate what is going on for you and
others.

You really should buy yourself an automatic blood pressure/heart rate monitor for your wrist.
This needs daily recording over extended time - particularly before and after orgasm (see my previous posts).

Keeping this record yourself will provide a lot of information on your pathology and a doctor is not going
to do this for you.

I dont really know the long term outcome of PCC but I think it just gets so bad that everyone
eventually gets diagnosed and treated.

I think seasonal POIS is evidence of adrenal gland hormone issues and chronobiology.

So, have an MRI scan privately - easily and cheaply done in Europe - but I think they can be expensive in the USA? Get a BP monitor - easily and cheaply bought. Collect MRI, BP and heart rate (rhythm) data and set against your symptoms.

regards
gpg
 

Offline A-Memo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19541 on: 16/05/2014 15:19:53 »
i have a question why does persons with POIS get those frustrating and strange facial expression with extreme facial exhaustion actually i would say the most ebrassing thing abouth the POIS is the facial changes that happen after orgasm and then you look like a person who havnt sleep for 4 days it mimmc extreme exhaustion while you are not exhausted ,, can any medication relieve this i dont htink vitamins and ssri can do so ?
any idea , infact i dont care about the fog as i care abouth the appeareance :S :S >:(
aadd to that i would like to say that i have severe gluten sensitivity to extent i cant sleep well for a day after ingestion of gluten , i have this sensitivity for 2 yrs but i had no idea about the causative agent , when i started eliminating gluten from diet the mental fogginess vanished but and i started getting milder symptoms of POIS but still significant and persist for days (5 days ) it seems like POIS have thing to do with gluten or the opposite , am thinking that may be by time of eliminating gluten i get better regarding the POIS issue but still the POIS symptoms are significant although they have reduced in severity 

also have read that gluten paly with the hormones and the secretion of adrenaline from the adrenal glands there probably a clue in this ;)
« Last Edit: 16/05/2014 15:31:48 by A-Memo »
 

Offline thereishope

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19542 on: 16/05/2014 16:48:07 »
hey have you tried completely eliminating gluten for a period of at least 6 months? and if so what were your results? do you believe its worth giving a shot?
 

Offline A-Memo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19543 on: 16/05/2014 22:05:10 »
i think i will be symptoms free by 6 month of gluten free,, but i feel symptoms post ingestion of gluten i get anxiety and mental fogginess ,, if you do so for sure it is worth trying but if u are not sensitive to gluten for sure it is okay ;)
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19544 on: 16/05/2014 23:10:51 »
I started eliminating gluten about a month ago ; I'll not draw any conclusion and will continue the experience for at least an other month  ; The idea behind this is gluten could cause some kind of malabsorption which could lead to various kind of symptoms which are specifically more intense after Orgasm.

After years of investigation, I'm now 100% sure that digestion is a least involved in the POIS mechanism

On my list of the potential culprit, there is also carbs and FODMAP's
 

Offline A-Memo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19545 on: 17/05/2014 09:47:38 »
have you been sensitive to gluten !!?
 

Offline narohWnarohW

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19546 on: 18/05/2014 22:15:50 »
Dear jferr,

My story is a lot like yours. Please read. I think you will be helped.

My "POIS" was very similar to yours in that it lasted for months after a single orgasm. It was ruining my life much like it was yours. What was the cause? Anxiety? Depression? Vitamin Deficiency? Autoimmune? Mental? NO TO ALL OF THOSE!! I took every vitamin imaginable, went to a phsycologist and two doctors who did not do much help, and even abstained. What finally worked?

I tried slow deep belly breathing while masturbating. Not only did I last much longer, but I even felt a pleasant "afterglow" feeling when I was done! I felt slightly lethargic and  tired but that was gone by the next day. I take minimal vitamins and have a very healthy diet. I tried the chlorella thing and I haven't noticed a difference.

Thank you for reading and the best of luck to you and everyone else!

 

Offline Thapelo

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19547 on: 21/05/2014 20:51:45 »
Hello readers,

I think i figgerd something out. If you have information about this, or you think i am wrong, please post it + send it to me private

Many pois suffers take Niancine, (vit b3) as a suplement, a half an our before orgasme. I think i figgered out why this helps.
Tryptofaan, as well as Ninance are required to make seratonine. (this is a neurotransmitter which make people feel good and happy, the opposite of a depression).
I read that in the western dieet you are short of vit b3. So supplementing this, does make you more seratonine, which reduces the effect of POIS.
This is why taking 5HTP also reduce the pois symptoms, like depression and anxiety.
Another point you might think is interesting, is that Niancine make you absorb your food better, which might reduce the diarree effect.

I just think all of this by reading some stuff,
notice, it is just an idea, if you have suggestions please also send me a private message so i can go further with my own "research"

Thank you for reading,
 

Offline LAPOISSE2

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19548 on: 22/05/2014 08:09:54 »
Hey Lars,

I noticed that already and i believe serotonin is involved in POIS ; i've taken SSRI for two years with at first a total suppression of my symptoms.

That being said, I dont' think that the mechanism is that simple ; the niacin you ingest to produce serotonin after 30 minutes, it should have to inhibitory/protective effect somehow.

My experience with niacin has never been conclusive but I need to give other tentatives ; 5HTP helped me.
 

Offline gondal4

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #19549 on: 24/05/2014 07:51:41 »
what about the research?where r the results?
 

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Re: Post Orgasmic Illness Syndrome (POIS)
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