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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6437692 times)

Offline underwater

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3300 on: 05/02/2009 00:07:32 »

I have always felt significantly better when I have had a large fruit salad made by my wife.


What if it were made by someone else? ;D

(sorry, couldn't resist).
One has to really pois before committing to such culinary risktaking.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3301 on: 05/02/2009 00:19:11 »

...do you realize other people have sex all the time and don't have side effects like we do?


My guess is that about 99%+ do.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3302 on: 05/02/2009 00:27:50 »

...the only reported cure for POIS in this forum...


Underwater, did you see B_Jim's list of cured/healed in the forum?
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3303 on: 05/02/2009 00:31:48 »

I have always felt significantly better when I have had a large fruit salad made by my wife.


What if it were made by someone else? ;D

(sorry, couldn't resist).
One has to really pois before committing to such culinary risktaking.

Touché  ;D ;D
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3304 on: 05/02/2009 00:38:24 »

sex was fine until I started drinking coffee I believe.


Fascinating for me, because i would love to explain mine that way. Nice and simple! But if this were universally true, POIS would be rampant, which it's not.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3305 on: 05/02/2009 00:42:30 »

Ever since sleeping on my side, I don't get NEs.  Occationally I'll roll on my back or chest unintentionally while sleeping and an NE will happen.


Limejuice, I hope this can work for others, too!
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3306 on: 05/02/2009 00:55:27 »
I dunno what theories i can have for the cause, i support the auto-immune one though, it kind of make sense.  Our heads are overloaded with hormones and maybe our body views that as a threat, maybe that is why i get immense headaches.... our bodies recognize the hormones as "foreigners" and then treats it like an infection.  I also find it weird the last time i had pois I was sneezing and "yellow" mucus was coming out of my nose, indicating an infection
 

Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3307 on: 05/02/2009 01:07:42 »
The theory that I have about POIS, is that the symptoms may be caused by a deficiency of one or more of the catecholamines of which noradrenaline may be the most relevant.

Deloun, I believe in this theory about noradrenaline (or norepinephrine). I thought exactly the same thing and wanted to post about this, but the fact that some people tried SNRI without success made me think that perhaps it's not true.

I have slightly this symptom you mention about genitals when in pois. Running, working, taking chocolate or coffee help (before the side effects for these foods). The symptom is mentionned in this page for the first remedy : http://www.hpathy.com/diseases/spermatorrhoea-symptoms-treatment-cure.asp

Also I know that coffee is increasing noradrenaline, so maybe before taking it NA is continuously low and after we take coffee the complete depletion occurs because we can't produce enough NA.

In a book I have it's written that sympathetic nerves exhaustion is causing pois, and I think these nerves are releasing noradrenaline.
http://en.wikipedia.org/wiki/Sympathetic_nervous_system

http://en.wikipedia.org/wiki/Noradrenaline


My MD also thinks I have a problem with noradrenaline because he wants me to take clomipramine or an equivalent.

Noradrenaline is highly involved in motivation and concentration.

I think the herb rhodiola is supposed to increase noradrenaline but for me it causes a complete insomnia, perhaps a sign that something is depleted.
 

Offline Finally

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3308 on: 05/02/2009 01:59:36 »
here is some information I found on adrenals:

http//www.patientsmedical.com/adrenals.html
 

Offline underwater

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3309 on: 05/02/2009 03:49:04 »
Catecholamines: A flow of consciousness rant---Signifying nothing or something???Read only at your leisure------------------------------------------------------------
For me, it is very logical to look at Catecholamines in trying to figure out the POIS riddle, because my POIS and GAD (flareups) share identical symptoms. Why haven't I solved POIS, when in the past I have solved GAD on and off? Good question!
Until this forum, I have not focused on the adrenal glands. I always thought about my brain. Girlwind seems to have influenced me in focusing on adrenal rehabilitation. That type of nutritional therapy involves considering adrenal fatigue. I might have made the mistake of always thinking I constantly had too much norepinephrine and epinephrine. Instead, the last few hours it dawned on me that I may be deficient in norepinephrine. Also, I have been noticing something weird lately. I sometimes go into the water fatigued and after a few laps feel just depleted. I fight not to get out. Then, after 15 minutes, I get some kind of rush, and I'm energetic. Could my enhanced metabolism be working with my new supplements to make some more norepinephrine/epinephrine? Could my frequent insomnia and lousy sleep be due to slow metabolism and reduced production of norepinephrine etc.? Could there be general metabolic shutdown in some of us after orgasm, thus causing failure of adrenals to produce what they're supposed to produce? What is metabolic shutdown? I don't know. I just coined this in my flow of consciousness post. However, could it be that the caloric expenditure is so overwhelming that the body refuses to reup for a few days. It's not going to "burn", it's going to not even rest. It's just quitting for a while.
What do epinephrine and nor do? Nothing!!! All the hormones and neurotransmitters in our body are thrown out of whack. So why do they come back? Why do we recover? Maybe goingcrazy is right; our brain (pituitary, hypo) sense trouble down there, and they desperately signal the conversion of other neurotransmitters (dopamine for example) to go and help the adrenals.
 

Offline martin88

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3310 on: 05/02/2009 03:57:44 »
This is interesting (if you didn't visit the wiki link about noradrenaline) : 

Biosynthesis :
Norepinephrine is synthesized by a series of enzymatic steps in the adrenal medulla from the amino acid tyrosine:

The first reaction is the oxidation into dihydroxyphenylalanine (L-DOPA) (DOPA = 3,4-DiHydroxy-L-Phenylalanine), catalyzed by tyrosine hydroxylase. This is the rate-limiting step.
This is followed by decarboxylation into the neurotransmitter dopamine, catalyzed by pyridoxal phosphate & DOPA decarboxylase.
Last is the final β-oxidation into norepinephrine by dopamine beta hydroxylase, requiring ascorbate as a cofactor (electron donor).


(If prolactin is increased, dopamine is decreased so the noradrenaline chain is broken.)

Norepinephrine, along with dopamine, has come to be recognized as playing a large role in attention and focus. For people with ADD/ADHD, psychostimulant medications such as methylphenidate (Ritalin/Concerta), dextroamphetamine (Dexedrine), and Adderall (a mixture of dextroamphetamine and racemic amphetamine salts) are prescribed to help increase levels of norepinephrine and dopamine.
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3311 on: 05/02/2009 05:23:59 »
Am with the dopamine, nonphenerine  /prolactin theory, because i have a two day high where i believe i have an overdose of dopamine or other neurochemicals that tame prolactin.  And because prolactin and dopamine are involved in a form of system where one determines the amount of the other. 
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3312 on: 05/02/2009 06:31:46 »
What I'm thinking is.  A lot of people with depression might actually have pois, you know?  I thought I had depression for about 2 years until I found out it was from the sex.  I was even prescribed lexapro, an antidepressant

And it's interesting I have an uncle who is depressed... maybe we have identical genes and he just hasn't figured out it is from sex

I dunno guys, it is ok to feel like crap once and a while, but everyday if you have sex... that''s just impossible to deal with... people around me think I'm a different person [:-'(]
« Last Edit: 05/02/2009 06:44:50 by goingcrazy »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3313 on: 05/02/2009 07:03:38 »

what do you mean by there will be others


Besides SSTAR, there are other "influentials" who can spread the good word about this forum. For example, I also wrote to the psychiatrist who wrote the NY Times article (alas, he didn't respond...but there will be...others!)
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3314 on: 05/02/2009 07:28:42 »

- Sceletium Tortuosum helps reducing POIS symptoms. It's a herb of which the main active alkaloid is mesembrine, which is a PDE4 inhibitor with a mechanism in a way similar to rolipram (11) that raises levels of noradrenaline.


Deloun, do you know if there's a relationship between your noradrenaline theory and PDE-5 inhibitors like Levitra? And with testosterone?
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3315 on: 05/02/2009 07:47:31 »

to be sure of the abstinence thing, I'm not going to have sex at all for a year and then do it and see what happens


what about NE's?
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3316 on: 05/02/2009 07:52:51 »

to be sure of the abstinence thing, I'm not going to have sex at all for a year and then do it and see what happens


what about NE's?


Lol i'll have to "lay on my side"
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3317 on: 05/02/2009 08:02:06 »

Deloun, I believe in this theory about noradrenaline (or norepinephrine). I thought exactly the same thing and wanted to post about this, but the fact that some people tried SNRI without success made me think that perhaps it's not true.


Martin, maybe your theory is still possibly correct. Effexor (SNRI) didn't work for me but maybe SNRI's just aren't powerful enough for norepinephrine balancing?
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3318 on: 05/02/2009 08:13:50 »

Why do we recover?


That question stumped me the most!!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3319 on: 05/02/2009 08:16:12 »

to be sure of the abstinence thing, I'm not going to have sex at all for a year and then do it and see what happens


what about NE's?


Lol i'll have to "lay on my side"

For a year?? :)
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3320 on: 05/02/2009 08:26:56 »

I dunno guys, it is ok to feel like crap once and a while, but everyday if you have sex... that''s just impossible to deal with... people around me think I'm a different person [:-'(]


Goingcrazy, it's really tough. But don't give up. Every time I wanted to give up the fight yet didn't, something new came along to make me glad I continued on. For over 30 years of this nonsense. We'll beat this thing yet!
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3321 on: 05/02/2009 08:57:39 »

I dunno guys, it is ok to feel like crap once and a while, but everyday if you have sex... that''s just impossible to deal with... people around me think I'm a different person [:-'(]


Goingcrazy, it's really tough. But don't give up. Every time I wanted to give up the fight yet didn't, something new came along to make me glad I continued on. For over 30 years of this nonsense. We'll beat this thing yet!


yes I know... its the days that I experience POIS I write this... lol had sex on sunday, it has only been about 3 days... Im just glad I can recover as long as I don't "do it"... I'm not saying recover as being cured... but recovery as a "can feel better and think clearer" or "feeling normal" stage from not having sex... so its basically being put on us if we experience this or not  (leaving out the possibility of nocturnal emissions)...  I have one question... did you notice even the slightest change of pois symptoms after your periods of abstinence and then having an orgasm again?


lol 30 years? that gives me much hope....jk im sure something is out there that'll help us
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3322 on: 05/02/2009 09:06:17 »

Why do we recover?


That question stumped me the most!!

I believe that we recover because our body filters out toxins on a daily basis... another possibility is our body stops attacking itself (auto-immune) because it god rid of what it needs to get rid of... other than that I have no other thoughts.

sometimes i get relieved from pois symptoms momentarily by chugging say a bottle of water, maybe that contributes to the removal of toxins?
« Last Edit: 05/02/2009 09:10:04 by goingcrazy »
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3323 on: 05/02/2009 09:24:07 »
Also... something very weird i forgot to say

during last year when I didn't know I had pois I was a senior in high school.  I decided to give blood at the blood drive.  It was weird for me, because I noticed a certain "freeness" of the symptoms that lasted for about an hour or two after giving blood, maybe it is hormonal
 

Offline rob58

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3324 on: 05/02/2009 12:52:52 »
Hi Guys,

I have been reading the postings for about a month now and finally caught up. Found you at the top of the list after googling "orgasm" and "fatigue".  Ironically my major symptoms are a bit better described by "brain fog" than by fatigue but I was sure that using brain fog as a term would not give me any results..

I have known that my POIS symptoms were linked to orgasm since I was 15 but have probably had POIS ever since I first had an orgasm.  I am now 50 years old and have suffered from the same symptoms with about the same intensity throughout.

My next post I intend to bore you with my symptoms and theories.  Thanks for being here.
 

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #3324 on: 05/02/2009 12:52:52 »

 

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