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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6441728 times)

Offline Bizzy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #500 on: 09/05/2008 01:11:16 »
After full ejaculation or orgasm a signal is sent from the testicles to the hypothalamus for the release of GnRH. The GnRH hormone travels from the hypothalamus to the pituitary and stimulates gonadotropin release. Gonadotropins travel to the testicles and stimulate testosterone production. This system is known as the HPG axis ( hypothalmic-pituitary-gonadal axis ).
Maybe in POIS, after ejaculation, rather than the HPG axis, the HPA axis gets activated. The HPA axis ( hypothalmic-pituitary-adrenal axis ) is responsible for releasing stress hormones including cortisol. This would mean that the end result after ejaculation would be more stress rather than more testosterone.

Research needs to be done as to why this axis crossover occurs.
Do you see how the adrenals are downstream from the true source of the problem, which is the hypothalamus ?
« Last Edit: 09/05/2008 12:16:28 by Bizzy »
 

Offline solution

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #501 on: 10/05/2008 06:45:55 »
Brain DHEA levels were significantly decreased by vitamin E deficiency in rats.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #502 on: 10/05/2008 18:16:02 »
After full ejaculation or orgasm a signal is sent from the testicles to the hypothalamus for the release of GnRH. The GnRH hormone travels from the hypothalamus to the pituitary and stimulates gonadotropin release. Gonadotropins travel to the testicles and stimulate testosterone production. This system is known as the HPG axis ( hypothalmic-pituitary-gonadal axis ).
Maybe in POIS, after ejaculation, rather than the HPG axis, the HPA axis gets activated. The HPA axis ( hypothalmic-pituitary-adrenal axis ) is responsible for releasing stress hormones including cortisol. This would mean that the end result after ejaculation would be more stress rather than more testosterone.

Research needs to be done as to why this axis crossover occurs.
Do you see how the adrenals are downstream from the true source of the problem, which is the hypothalamus ?


Bizzy, this is excellent. Now, do you have any suggestions as to how we can take this to the next step? Recruit a research scientist for this Forum? Thank you!

ps - I wouldn't wish POIS on a poor rat ;D
« Last Edit: 10/05/2008 18:26:11 by demografx »
 

Offline msl

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #503 on: 11/05/2008 09:19:32 »
Hi guys, Thank you very much for replies, they mean a lot. Its reassuring to know there are people out there who understand. I had another nocturnal emission last night :/ but as you can see.. Im still here...

I do not know if this has already been posted but i found this article:
newbielink:http://www.reuniting.info/science/sex_and_addiction [nonactive]
particularly go down to sex's hidden hangover
 

Offline John21

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #504 on: 11/05/2008 11:50:58 »
... sex outside of love (oxytocin) is dangerous.

This glove fits perfectly on the hand of Christian theology.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #505 on: 12/05/2008 21:13:42 »
TO RAPIDGAMING

Welcome back!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #506 on: 12/05/2008 21:25:28 »

Demografx feels much better with dopaminergic Levitra.


B_JIM,

I don't know if you saw my previous question. I'm sorry if I missed your reply.

(1) I asked if you can please explain what you mean by "dopaminergic Levitra"

(2) And you also referred to Levitra in another post as a "stimulant".

Would you kindly explain?

Thank you!
« Last Edit: 12/05/2008 21:27:26 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #507 on: 12/05/2008 21:30:29 »
Hi guys, Thank you very much for replies, they mean a lot. Its reassuring to know there are people out there who understand. I had another nocturnal emission last night :/ but as you can see.. Im still here...

I do not know if this has already been posted but i found this article:
http://www.reuniting.info/science/sex_and_addiction
particularly go down to sex's hidden hangover

RAPIDGAMING,

Very interesting article! I think it agrees with B_JIM's theories.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #508 on: 12/05/2008 21:36:46 »
QUESTION TO ALL

Does anyone else feel this way: For me, POIS symptoms feel like NOTHING ELSE I experience, either when I'm sick or well. They are unique. The drain of energy is different. My fingertips feeling drained are so unusual, there is nothing else like that feeling in my life. How does everyone else feel with POIS symptoms? Are they similar to any other symptoms in your life? Please let me know.
 

Offline Bizzy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #509 on: 13/05/2008 01:00:34 »
Demografx, I agree the symptoms are very unique. There is a huge lack of physical and mental energy. Severe depression is the most significant illness I experience. I wonder if this is true for others ?

Demografx, you asked me above what the next step should be. I think a letter should be sent to the head of research endocrinology directed at several universities. Within the letter outline a discription of the illness and call it POIS. Make a reference to this forum with its URL.
« Last Edit: 13/05/2008 01:24:02 by Bizzy »
 

Offline hk1979

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #510 on: 13/05/2008 19:31:05 »
my POIS is similar to things I do that deplete my adrenaline, like playing soccer or rugby for more than 2 hours, I get very tired and sometimes nauseas, dehydrated. if anyone plays tennis or squash or does very physical extreme sport for more than 3 hours, tell us if your feelin the day afterwards is similar to POIS. I guess if you are fit, then your POIS is also not as bad as the days when you were unfit? With fit I mean trained to endure long physical activity, and good lung pump to muscular and nervous system.

A good indication may be: does POIS make your legs and arms stiff. Like you feel you cannot stretch them easily?
 

Offline msl

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #511 on: 14/05/2008 09:21:42 »
My POIS symptoms are unique, different to when I have done lots of sport. Mine include

Mental Fog, Can't concentrate or think logically, work things out or recall necessary things.
Severe Depression
a little physical fatigue and headache
Large pupils

Actually to mention on that stretching thing i did find it harder to stretch in a pois cycle, and I used to do lots of  hard stretching. I also have pretty bad OCD

And guess what, i had another wet dream last night! and I have an A2 Module tomorrow! Doesn't it just make you glad to feel alive..
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #512 on: 14/05/2008 19:15:54 »
Demografx, I agree the symptoms are very unique. There is a huge lack of physical and mental energy. Severe depression is the most significant illness I experience. I wonder if this is true for others ?

Demografx, you asked me above what the next step should be. I think a letter should be sent to the head of research endocrinology directed at several universities. Within the letter outline a discription of the illness and call it POIS. Make a reference to this forum with its URL.

This is an excellent idea, Bizzy! I can help research the universities' email addresses, but would anyone here be willing to step forward and draft a letter? I don't feel that my writing is scientific enough.

HELLO FELLOW POIS SUFFERERS! **ANY VOLUNTEERS?**
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #513 on: 14/05/2008 19:30:59 »
TO B_JIM

B_Jim, thank you very much! That is a fascinating explanation of what happens with Levitra.

Calm?  ;D Not me! Haha.

Even with a 75% POIS-cure with Levitra, I am so sick and tired of the POIS symptoms - even "only" one day - that I still avoid sex these days.

B_Jim, maybe we can work together? Maybe you can help to begin a draft of a letter - as Bizzy suggested - to universities and I can help to edit it? Your scientific understanding is much better than mine and I can help with grammar, punctuation, spelling, etc. If you agree, either post here or feel free to email me.

Thanks!
« Last Edit: 14/05/2008 21:41:11 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #514 on: 14/05/2008 19:34:45 »
My POIS symptoms are unique, different to when I have done lots of sport. Mine include

Mental Fog, Can't concentrate or think logically, work things out or recall necessary things.
Severe Depression
a little physical fatigue and headache
Large pupils

Actually to mention on that stretching thing i did find it harder to stretch in a pois cycle, and I used to do lots of  hard stretching. I also have pretty bad OCD

And guess what, i had another wet dream last night! and I have an A2 Module tomorrow! Doesn't it just make you glad to feel alive..


RAPIDGAMING, I'm sorry to hear about the dream again, but at least your spirits and sense of humor have improved! ("doesn't it just make you glad to feel alive"---haha)

Best wishes, RAPIDGAMING !
« Last Edit: 14/05/2008 20:25:26 by demografx »
 

Offline hk1979

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #515 on: 15/05/2008 15:32:46 »
rapidgaming

thank you very much for the article you posted, it made very interesting reading, and also changed my perception on dopamine! I always felt without ambition with POIS but never guessed it is dopamine.
 

Offline jeroboam

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #516 on: 15/05/2008 16:03:42 »


I do not know if this has already been posted but i found this article:
newbielink:http://www.reuniting.info/science/sex_and_addiction [nonactive]
particularly go down to sex's hidden hangover

RAPIDGAMING,

Very interesting article! I think it agrees with B_JIM's theories.
Quote for the truth! I've read about this dopamine-dropping phenomen before.


I think the better way of solving the problems this "Syndrome" is causing, is to prevent it from happening. Everytime a man ejaculates he loses valuable semen. And obviously it also has an effect on various complex regulating systems for varieble substances in the mind and body. This causes us to feel tired, sexually not interested, etc.. for quite a while.


My view on the situation is that everyone suffering from this should learn to have an orgasm withouth ejaculation. I think the ejaculation and not the orgasm itself triggers all these "bad" things to happen.
There's only advantages to come from learning this. This way you can also experience the good effects off having sex with a partner. (i.e. longevity instead of dying sooner by wasting valuable semen)

It all comes down on training your PC-muscle. But be careful! This muscle is easy strained, and this works contraproductive.
For all who wants to learn this, I've uploaded a book at newbielink:http://rapidshare.com/files/115102010/allnight.zip.html [nonactive]. This book is about learning this.

Also the book of Mantak Chia "Mantak Chia - Taoist Secrets of love - Cultivating male sexual energy.pdf" is an interesting read, and gives insight why Ejaculation even isn't good at all.

I'm hoping to master this myself. Anyone who succeeds at mastering this technique, please post your results regarding the POIS.

If anyone has comments or questions.. Please don't hesitate to ask or say.

Greetz from europe
« Last Edit: 15/05/2008 16:18:44 by jeroboam »
 

Offline cdma77

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #517 on: 15/05/2008 17:53:59 »
I just had an idea.  If someone is suffering from nocturnal emissions they may want to try kegal muscle exercises.  It may help, since it helps with PE.  I have had a recent problem with getting a bit of semen coming out once I finish urinating.  It may not be semen but fluid from my prosate since I haven't been having sex or masturbating.  When I loose this fluid I get a lot of the same symptoms as POIS, but not as bad.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #518 on: 15/05/2008 20:09:49 »
TO JEROBOAM

jeroboam, I tried Mantak Chia's techniques on and off for years, with no improvement in POIS. Ejaculation is not the key, it's the orgasm. The orgasm apparently sets off numerous bodily activities that affect POIS directly. I was very disappointed. I even spoke with Mantak Chia and his assistants in Thailand.
 

Offline jeroboam

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #519 on: 15/05/2008 22:44:27 »
So you were able to have an orgasm without ejaculation and you'd still have the POIS?

I don't understand, because the link rapidgaming provided stated that with those techniques the dopamine-hangover is avoided...
Or she uses another technique? Does anyone know?


for others that don't know: Kegel-excercises are to strengthen the PC-muscle
« Last Edit: 15/05/2008 22:56:23 by jeroboam »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #520 on: 17/05/2008 03:25:24 »
So you were able to have an orgasm without ejaculation and you'd still have the POIS?

I don't understand, because the link rapidgaming provided stated that with those techniques the dopamine-hangover is avoided...
Or she uses another technique? Does anyone know?


for others that don't know: Kegel-excercises are to strengthen the PC-muscle

Yes, I practiced Mantak Chia's techniques and sucessfully avoided release at orgasm. No effect on POIS. As for the link,  there are as many "theories" as the number of people on the planet. I was very disapointed.
 

Offline jeroboam

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #521 on: 17/05/2008 09:54:44 »
So the link off Rapidgaming about the dopamine-hangover... is correct? And this is causing the POIS?

So the techniques they are learning in the book they advertise on the site (book named "peace between the sheets"), is about having sex without having orgasm?
To me that seems the only way to avoid the dopamine-hangover, if what I posted above is all correct.
« Last Edit: 17/05/2008 10:39:13 by jeroboam »
 

Offline solution

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #522 on: 18/05/2008 00:59:21 »
What if you can recover quickly that dopamine released? I suppose watching porno movies...or getting very excited again after an orgasm, could be a solution? letīs try...
« Last Edit: 18/05/2008 01:00:59 by solution »
 

Offline solution

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #523 on: 19/05/2008 06:02:30 »
...During the "hangover," or "low-dopamine" portion of the cycle, you may feel abandoned, or as if someone is demanding things from you in ways that you cannot tolerate. Or you may desperately seek new highs (alcohol, sweets, new partners, pornography, and so forth) to raise your dopamine levels again...

...Dopamine is behind a lot of the desire we associate with eating and sexual intercourse. Similarly, all addictive drugs trigger dopamine (the "craving neurochemical") to stimulate the pleasure/reward center. So do gambling, shopping, overeating and other, seemingly unrelated, activities. Go shopping: dopamine. Smoke a cigarette: dopamine. Computer games: dopamine. Heroin: dopamine. Orgasm: dopamine. They all work somewhat differently on the brain, but all raise your dopamine.

You get a bigger blast of dopamine eating high-calorie, high-fat foods than eating low-calorie vegetables. You may believe that you love ice cream, but you really love your blast of dopamine. You're genetically programmed to seek out high-calorie foods over others. Similarly, dopamine drives you to have sex over most other activities. With dopamine as the driving force, biology has designed you to engage in fertilization behavior to make more babies, and urges you to move on to new partners to create greater genetic variety among your offspring...




http://www.entelechyjournal.com/pulling_away_after_sex1.htm [nofollow]
 

Offline solution

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #524 on: 19/05/2008 06:32:01 »
...Now Apomorphine HCl, a dopamine agonist that stimulates erection, is being approved, and is already for sale in Europe...
...A dopamine agonist drug, therefore, produces effects similar to dopamine in the brain...


Maybe is Levitra acting as dopamine agonist?


http://edlogs.blogspot.com/2007/12/super-size-orgasms.html [nofollow]
 

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #524 on: 19/05/2008 06:32:01 »

 

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