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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6456957 times)

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #525 on: 20/05/2008 00:06:47 »
...Now Apomorphine HCl, a dopamine agonist that stimulates erection, is being approved, and is already for sale in Europe...
...A dopamine agonist drug, therefore, produces effects similar to dopamine in the brain...


Maybe is Levitra acting as dopamine agonist?


http://edlogs.blogspot.com/2007/12/super-size-orgasms.html

solution, thank you for that very interesting info. I think B_Jim believes that to be the case, i.e., a Levitra-dopamine connection.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #526 on: 20/05/2008 00:30:51 »

Demografx, I will send you a beginning of letter next week.


Thanks, B_Jim! Meanwile, I have asked The Naked Scientists people here if they can provide any university contacts.

Someone else said they had a contact name or suggestion at Oxford? Please let me know! Thanks.
 

Offline Bizzy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #527 on: 20/05/2008 14:35:46 »
If a research team does decide to look into this condition, I wonder how many of you will be willing to travel and participate ??
 

Offline pyropeach

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #528 on: 20/05/2008 19:37:30 »
I'd be willing to participate, HANDS DOWN.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #529 on: 20/05/2008 20:56:51 »
If a research team does decide to look into this condition, I wonder how many of you will be willing to travel and participate ??

Interesting, I didn't think of this as personal study, but sure, it could take that route. I see this Forum as a completely democratic process, so you decide. I was thinking we would start by having a research endocrinologist study the hundreds of posts here at POIS Forum and then giving us recommendations as to the next step.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #530 on: 20/05/2008 20:58:08 »
I'd be willing to participate, HANDS DOWN.

Thanks, pyropeach!
 

Offline hk1979

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #531 on: 20/05/2008 23:24:23 »
demografx

I think the problem of this research will be that everybody would like to stay anonymous. Even if this eventful discovery of the solution to POIS is groundbreaking, nobody would like to be named as subjects with POIS....

Therefor the endocrinologists should treat all test subjects and control subjects as anonymous.
 

Offline hk1979

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #532 on: 21/05/2008 12:44:47 »
solution thanks for the article:

http://edlogs.blogspot.com/2007/12/super-size-orgasms.html [nofollow]

very interesting. the question is how to cut out all the highs of life, and the solution will probably very boring!

 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #533 on: 21/05/2008 19:50:13 »
demografx

I think the problem of this research will be that everybody would like to stay anonymous. Even if this eventful discovery of the solution to POIS is groundbreaking, nobody would like to be named as subjects with POIS....

Therefor the endocrinologists should treat all test subjects and control subjects as anonymous.

Thank you, HK, I agree 100%. As everyone else, I certainly wish to remain anonymous! But I don't think we're anywhere near that point. If anyone thinks differently, please post: I see this first phase simply as a review of all the posts on this POIS Forum, and a recommendation from, an endocrinologist. Then we can decide what we might do next. So, no names needed, just the posted usernames here, but more importantly: the posted information, which contains a wealth of history, experience, solid theories, etc.
« Last Edit: 21/05/2008 20:13:07 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #534 on: 21/05/2008 20:10:49 »
QUESTION, POIS STUDY

Is everyone agreed that the specialist we wish to help us research a cure for POIS is: a research endocrinologist? If anyone disagrees, please post your thoughts within a week, by May 28. Thank you.
 

Offline Bizzy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #535 on: 23/05/2008 01:35:13 »
Demografx

This is certainly an endocrinology and neurology area.
The neurological aspect of POIS will be complex and so it would be difficult to persuade a doctor that anything is wrong. A lot of doctors are dismissive and love to cry placebo.
So it is better to take the endocrinology path, which may show hormonal abnormalities.
« Last Edit: 24/05/2008 02:14:47 by Bizzy »
 

Offline girlwind

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #536 on: 23/05/2008 18:15:39 »
I can't possibly be the only woman who has this syndrome? I see only men chatting on this website, and in my google search I didn't
find any POIS referring to women. But I must say that it comes as a relief to hear that there is a name for this bizarre post-orgasmic
exhaustion, and that other people are also attempting to find answers and remedies. I have had many of the symptoms described here
after engaging in orgasmic sex--the physical, mental and mood exhaustion, brain fog and flu-like symptoms that last for 3-10 days
after the "event."

For me this all started with a bigger problem back 30 years ago, when I collapsed with Chronic Fatigue Immune Deficiency Syndrome,
(CFIDS) also known as Chronic Fatigue Syndrome. Since then, the fatigue I feel after orgasm has not gone away, despite the fact that
my overall health has generally improved. Some of you have addressed the issue of neurotransmitters, as well as the auto-immune
part of the equation, both of which are KEY factors in dealing with CFIDS, so this is something that I have some experience with.

One thing that has helped me to recover from the overall exhaustion of CFIDS, and to somewhat remedy the orgasmic exhaustion has
been adrenal boosting herbal remedies and vitamins, like Siberian ginseng, schizandra, and large doses of pantothenic acid (up to
5000 mg) in 1000 mg doses, spread out throughout the day with 2000 mg. of Vitamin C per pop. Also important has been managing
stress and avoiding anything close to burn-out, which drains the adrenals and makes the fatigue worse. And getting deep sleep has
been really important too. The amino acid L-Tryptopan has been most beneficial for sleep, and since it is a precursor for serotonin
production, this goes back to the issue of improved neurotransmitter availability in assisting overall recovery from fatigue. Repairing
adrenal exhaustion also has helped my immune system functioning, as there is a direct link between being overly tired/drained and
the tendency to become ill with colds and flus.

But unfortunately, the best remedy has been to omit the orgasm from my sexual repertoire. Which truly sucks. Many women do not
even have orgasms, and so it feels disappointing to forgo what happens naturally for the sake of my overall health. Although I have
noticed over the years, that when I repress the urge to cum for too long, my body will rebel against this eventually and give me an
orgasmic dream in compensation to the enforced repression.

Still, my main question has to do women with this syndrome... How many other woman out there have this?  Is POIS mostly a male
syndrome? Or are many women in the dark about this, as I was, until I found this website?  What are the stats on this? Has anyone
taken the time to do research? And where are they?
 

Offline Guthrie

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #537 on: 24/05/2008 03:49:46 »
Hi girlwind,

Yes, it seems that you are the only woman so far on this site who has reported having POIS symptoms.  It is interesting to know that it affects women also--perhaps that can help in figuring out causes/cures.  Since there may be some things that differ between male and female sexual response, the fact that POIS seems to affect both men and women may indicate that with regard to POIS, the causal factor is something common to both male and female orgasm.  For instance, there was some debate in this forum whether orgasm without ejaculation could prevent POIS--but if women get it too, then it probably is something related to orgasm itself, not to ejaculation.

Perhaps other women will write in, now that you have written!

The link to Chronic Fatigue Syndrome is also interesting--perhaps some CFS treatments could work for POIS (although they don't seem to have fully done so in your case).
 

Offline Guthrie

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #538 on: 24/05/2008 04:31:40 »
In fact, the list of Chronic Fatigue Syndrome symptoms at this site:
http://www.cfids.org/about-cfids/symptoms.asp
almost make it seem as though POIS could be a 'short-term' or 'specific-occasion-induced' form of CFS.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #539 on: 24/05/2008 04:38:35 »
In fact, the list of Chronic Fatigue Syndrome symptoms at this site:
http://www.cfids.org/about-cfids/symptoms.asp
almost make it seem as though POIS could be a 'short-term' or 'specific-occasion-induced' form of CFS.

Guthrie, that's exactly what my psychiatrist thought!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #540 on: 24/05/2008 04:57:24 »
WELCOME GIRLWIND!

Since only men have come around, I assumed it was strictly a male problem! Thank you for enlightening us, girlwind.

Guthrie, I agree, now other women can find us and post, too. And as I mentioned earlier, from personal experience, I'm convinced that orgasm, not ejaculation, is the key to POIS.

Girlwind, as you can see from earlier posts, Levitra "cures" 75% of my symptoms, a combination cure of POIS-cycle length and severity. If it's a potential cure, I wonder what that implies for women since it's a male ED drug? Some people here have posted ideas that it's just a part of Levitra that does the trick for POIS. I agree.

I hope you read the posts relevant to our looking for a research endocrinologist to study all the posts here and make some sense of it all. Your input is most welcome. I suspect that somewhere in all the information revealed in this POIS Forum lies a cure for this horrible malady. I think I can safely say "horrible" for all afflicted because it has ruined a chunk of our lives. Even when we are not actively suffering POIS symptoms, they can feel like they're "just around the corner" waiting to happen!

Girlwind, you ask great questions. Almost no research has been done to date. If you Google Marcel Waldinger, a Dutch MD, he is the only published POIS researcher known, and he first described the name Post Orgasmic Illness Syndrome, or POIS. The number of subjects he studied is very small, so this POIS Forum is probably the largest single repository of POIS knowledge!

Girlwind, a question for you: do your orgasmic dreams also create POIS? Welcome again.
« Last Edit: 24/05/2008 05:02:45 by demografx »
 

Offline jeroboam

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #541 on: 24/05/2008 18:18:02 »
Have any other persons also noticed the corelation between the quality of the orgasm (the feel good feeling (=amount of dopamine released when orgasming?)) and the bad after-effects? That they are worse when you have a 'better' orgasm?
 

Offline girlwind

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #542 on: 24/05/2008 18:59:31 »
Hello guys! It is feels somewhat weird to be the only woman in the discussion so far, but hopefully I will inspire other women to come forward. I actually wrote
one of the Berman sisters a few weeks ago about my symptoms--Jennifer Berman, who is a MD gynecologist in LA specializing in women's sexual issues. When
I described my symptoms to her, she responded in her email back to me that I had "orgasmic disorder," and that I "wasn't alone." But when I looked up orgasmic
disorder, it was all about women who were NOT orgasmic, not about women who had post orgasmic exhaustion. I'm going to email her the link to this discussion
today, so she can get some education about POIS. Unfortunately, in my way-too-long experience with both CFIDS and POIS, medical doctors have too often proven themselves to be over-rated and under-qualified to deal with the mysterious and complex intricacies of the immune and endocrine systems. And after what I have
read here and experienced in my own body, I totally agree that any research about POIS should be focused in large part on the endocrine system. Though I also
think there's a significant link to the immune system, due to the fact that POIS for many of us includes the onset of cold or flu-like symptoms.

Even if my orgasm happens in my sleep, in a dream state which I awaken from mid-orgasm, I experience POIS. However, I have found that those orgasms that
happen spontaneously in a dream state have shorter lasting negative effects than the ones I have "consciously." I've actually kept track of when the dream state
orgasms occur, and over 90% of them have happened mid-cycle, right around the time of ovulation. I've speculated that the exhaustion I feel is less just because
of that. At mid cycle is when progesterone peaks in women... and progesterone is one of the top of the chain steroid hormones. I think this means that I have
enough of an "excess" of steroid hormones to spare at those times, and maybe that's why the POIS symptoms aren't as bad then. Also, because it's the adrenal
cortex that produces the steroid hormones, I think that's why adrenal boosting supplements have helped me to sometimes remedy the POIS symptoms.

demografx: I googled Levitra and read up a bit about it. It's known as a PDE5 inhibitor--does anybody know what that means? I know Levitra increases blood
flow, but HOW exactly it works in the body might be a clue as to why it helps the symptoms of POIS. Because there are some potentially very risky side effects
from taking Levitra, especially prolonged use--like "serious cardiac events" (as in heart attacks), penile tissue damage, and potential loss of vision, due to a
decrease of blood flow to the optic nerve--that isn't something I would want to experiment with. In general I am more inclined to using vitamin supplements,
herbal remedies and hormonal cremes. (I've had far too many side effects and allergic reactions to pharmaceuticals.)  But I'd like to know more details about
how the chemistry of Levitra affects steroid hormone production, or if there is a link along those lines.
 

Offline solution

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #543 on: 25/05/2008 08:06:41 »
The process in my view is: orgasm generates something in the brain that generates something in the stomach that generates all ills.
So I think that not finding a remedy for the brain we should tackle the problem in the stomach that produces so many ills
 

Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #544 on: 25/05/2008 20:47:59 »
It's been a while since i last posted anything in this thread.

I was just wondering if anybody would be willing to meet other people with this condition in second life?

I would like to create such a place but I have no idea wether people would come.
« Last Edit: 26/05/2008 02:13:40 by imre1 »
 

Offline pyropeach

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #545 on: 25/05/2008 20:58:32 »
It's known as a PDE5 inhibitor--does anybody know what that means?

PDE5 is an enzyme that is within the pathway of muscle contraction for smooth muscle tissue.  If this enzyme is inhibited, the smooth muscle cannot contract and remains relaxed causing blood to remain in the penis to prolong erections.  PDE5 is also found in lung tissue.

I was just wondering if anybody would be willing to meet other people with this condition in second life?
 

What do you mean by second life?
 

Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #546 on: 26/05/2008 02:13:16 »
What do you mean by second life?

The metaverse: http://secondlife.com/

Where people can meet almost face to face. In a level that very closely resembles real live communication.
 

Offline imre1

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #547 on: 27/05/2008 08:58:47 »
Hi fellow POIS sufferers

Do you folks find that POIS seriously affects every aspect of your life everyday ?.
I find this a very powerful illness which affects me everyday. This is because the mental symptoms linger for so long after an orgasm.


Here is my story thay I recently sent to an emotional support group:

I have had an illness my entire live that makes me allergic to sex. This means that I often have very heavy pain. On top I have fear for everything that has to do with sex and I am often afraid to go to sleep (because of the chance on wet dreams).

For this illnesss there is currently no treatment and I know no doctor who can help me. All doctors that I have visited send me away without answer. Only since shortly I know what is wrong with me. Before that there was only pain, a lot of pain.

On a relational level I can not handle relationships. Because of this illness I am locked up at home and I have a lot of problems to leave home. I have also a lot of fear to handle girls. Therefore I also don't have any friends.

Since shortly I am on second life. I find second life very fun because it allows me to at least virtualy go out.

But when I look around me in second life I see everywhere people that have found other people. This is very hard for me because it reminds me of what I will never have.

I have been in many places in second life and I have met a lot of people. Among which a lot of gay people. Most people have problems with gay people but I find them to be the nicest people.

With my illness I am also a little jealous of them. They at least have people that are like them. Like me there is nobody. I am staying alone and I don't belong anywhere. With hetero people I don't have so much a connection. They are always too much busy with sex.

 

Offline chris

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #548 on: 27/05/2008 22:33:15 »
It's been a while since i last posted anything in this thread.

I was just wondering if anybody would be willing to meet other people with this condition in second life?

I would like to create such a place but I have no idea wether people would come.

Why don't you come to the Naked Scientists broadcast in second life on Sunday (10am SL Time / 6pm UK Time) and then you can meet after the show and chat...?
 

Offline Bizzy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #549 on: 28/05/2008 02:09:55 »
Imre1 thanks for your previous post. It lets us know that this condition can be part of a greater complex for many POIS sufferers. The greater complex can come in different flavours and some people have it pretty bad.
I think most of us have some core POIS symptoms such as tiredness, brain fog, speech difficulty, depression and flu like symptoms. Some of us have a few odd-ball symptoms as well that noone else seems to have. We can be sure that these are part of POIS too because they happen everytime post orgasm for that person.
« Last Edit: 28/05/2008 02:16:52 by Bizzy »
 

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #549 on: 28/05/2008 02:09:55 »

 

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