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Author Topic: Post Orgasmic Illness Syndrome (POIS)  (Read 6461765 times)

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5700 on: 03/10/2009 02:55:25 »

I am interested [in research/clinical trial of POIS and testosterone].

Hell i'll be their guinea pig if they want to try solutions that have a moderate % to kill me even. Anything to find a REAL viable consistent solution.


Thanks, Def! Any other takers?
 

Offline Paulrx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5701 on: 03/10/2009 10:07:21 »

yeah i can do that but it doesnt work for me, as i've stated before whatever causes the "feel good" sensation, with or without ejac, causes my POIS

Do all POIS sufferers have their POIS onset triggered by the orgasm or do some have it triggered by the ejaculation?

Have some POIS sufferers tried a technique called prostate milking to see if it could alleviate their sexual tension without the need to have an orgasm, and maybe therefore avoid triggering POIS?
« Last Edit: 03/10/2009 10:11:10 by Paulrx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5702 on: 04/10/2009 01:29:46 »

Paulrx, welcome. Please tell us about your experience with POIS.
« Last Edit: 04/10/2009 20:10:49 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5703 on: 04/10/2009 01:42:09 »


Paulrx, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/poiswebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for over 2 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus more than 350,000 page visits. Not bad for a rare malady!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5704 on: 04/10/2009 01:45:54 »

Paulrx, this post might help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

 

Offline lauracostis

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5705 on: 04/10/2009 19:47:28 »

Quote from: demografx on 28/09/2009 19:53:09
Would anyone here be interested in my approaching a testosterone manufacturer (like Androderm/Watson Pharmaceuticals) to see if they would be interested in conducting research, clinical trials into the use of testosterone as a way to alleviate POIS - for low- testosterone and normal-testosterone POIS sufferers alike? Feel free to post your answer here or to send me a Private Message.



I think we have nothing to lose if they conduct a research. I'm reticent with clinical trials, except if they show me something wrong in my body, maybe with androgen receptors, liver, estrogens, .. I was reading in some papers of a lab "elevated levels of T suggests poor utilization"(something like tht), if this is true blood T tests are BS and we need more research.


Thanks, Martin!

OK, if I understand the response to my post correctly, there are only two (2) people here who are possibly interested in a clinical trial/research study of POIS and testosterone. Which is not enough for me to approach Watson Pharmaceuticals, Inc. If I'm wrong, and you are interested, please let me know by posting your interest here or by PM! Thank you.

I am interested.

Hell i'll be their guinea pig if they want to try solutions that have a moderate % to kill me even. Anything to find a REAL viable consistent solution.


thats awsome, i feel the same way
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5706 on: 04/10/2009 20:07:37 »

Isn't that [testosterone use] why body builders have smaller testicles?


And you know this how?  :)
 

Offline bruxe

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5707 on: 04/10/2009 20:47:17 »
hi

someone tried the "Magnesium chloride" ?
 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5708 on: 05/10/2009 02:26:49 »

Isn't that [testosterone use] why body builders have smaller testicles?


And you know this how?  :)

From word of moutha and several teachers and partly experience. you use testosterone without having defieciency your body starts to shut down its operation. 
When i used dhea( without guidiance i will say i noticed shrinkage in my testicles) not the same as testosterone but the precusor. 


 

Offline CertainlyPOIS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5709 on: 05/10/2009 02:28:14 »
I will be interested in it, if am able to show that there is a drop in testosterone levels compared with pre pois and post pois.
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5710 on: 05/10/2009 06:34:05 »

bruxe, welcome to the POIS thread of The Naked Science Forum!



You asked about magnesium chloride. Here are some forum discussions we've had that include it:http://www.google.com/search?hl=en&q=magnesium+chloride+POIS+site%3Ahttp%3A%2F%2Fthenakedscientists.com&aq=f&oq=&aqi=


Here are some POIS resources which may be helpful to you:

Our new POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/poiswebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

And filling out the POIS survey created by "Counterpoints" will enable you to share POIS information and details with others here. This will also enable us to work more easily with outside researchers by having more organized data available about us:
http://pois.olympe-network.com/

POIS Research Study

We have a copy of the first and only study on POIS by Dr. Marcel Waldinger,MD and Dr. David Schweitzer, MD.

If you want a copy (PDF), send me a Private Message with your regular email address and I'll send you back the PDF.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show the medical world - which often shows little understanding and is sometimes skeptical of our condition - that POIS has scientific underpinnings and that POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapist community. This can help fight the immediate reaction of some: IT'S NOT "ALL IN OUR HEADS"!

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum for over 2 years, which has attracted over 150 POIS sufferers worldwide who have posted here, plus more than 350,000 page visits. Not bad for a rare malady!
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5711 on: 05/10/2009 06:35:30 »

bruxe, this post might help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: over 2 years' worth of posts from 150+ Forum members, and an additional 150 POIS sufferers found on the Internet, but not on this forum.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://www.thenakedscientists.com/

for example, I tried
demografx POIS site:http://www.thenakedscientists.com/

and 1,000+ results came up for "demografx" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.

 

Offline devastated

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5712 on: 05/10/2009 13:40:22 »
Hello again guys,

I kept on researching POIS a bit more lately and I was wondering... how many of you have you been experiencing visual snow and tinnitus (intense and / or persistent ear buzzing) during the peak period of POIS symptoms?

When I refer to visual snow, I mean something like this:
newbielink:http://www.visionsimulations.com/index.php?option=com_content&task=view&id=78&Itemid=171 [nonactive]

For more info about it, please check: newbielink:http://www.visualsnow.com/ [nonactive]

It seems that visual snow is connected somehow to tinnitus, derealisation / depersonalisation syndromes and depression as part of some yet unnamed umbrella neurological disorder.

I'm not sure if the above symptoms are caused by chronic POIS or are intensified by it, however I have the suspicion that the abnormal post-ejaculative organic stress that most of us undergo (during the strainful effort of our body to replenish vital substances that are totally critical to its proper function), somehow cannibalises the nervous system or causes some short of temporary neurological damage which adds up with the passing of years and is proportional to the frequency and intensity of the ejaculations. I don't know if it's only the neurotransmitters that are involved or there is also some actual amassing cell damage occurring as well, but I find it really worrying.

I also wonder, could POIS be caused by some genetic defect or inherent brain/parasympathetic nervous system and / or immune system anomaly which affect the semen production process of the sufferers, producing all these symptoms?

More related links:
newbielink:http://www.benzo.org.uk/der.htm [nonactive]
newbielink:http://en.wikipedia.org/wiki/Depersonalization_disorder [nonactive]
newbielink:http://en.wikipedia.org/wiki/Derealization [nonactive]
newbielink:http://en.wikipedia.org/wiki/Tinnitus [nonactive]
newbielink:http://thosewithvisualsnow.yuku.com/directory [nonactive] (Forum of visual snow sufferers - interesting for comparative research)
« Last Edit: 05/10/2009 14:43:46 by devastated »
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5713 on: 05/10/2009 20:49:03 »
I was in my college psych class today and we were going over hormonal and neural functions,etc.  One thing I noticed was that POIS resembled a lot the serotonin pathways in our brain :

http://images.google.com/imgres?imgurl=http://www.cnsforum.com/content/pictures/imagebank/hirespng/Neuro_path_SN_DPN.png&imgrefurl=http://www.cnsforum.com/imagebank/item/Neuro_path_SN_DPN/default.aspx&usg=__9gEWRkFyhL2aUM2_PwqpQ6mWVsA=&h=2433&w=1990&sz=629&hl=en&start=1&um=1&tbnid=ywDqVZtzZvzd2M:&tbnh=150&tbnw=123&prev=/images%3Fq%3Dserotonin%2Bpathways%26hl%3Den%26um%3D1

than compared with any other pathway/neurotransmitter.  I have now proved to myself that not only is POIS caused by orgasm, it is also caused by even just sexual stimulation (I have been doing tests the past 2 weeks).  With headaches, etc. alot of the symptoms of orgasmic POIS.  At least this is for me.  But my theory is just that any type of brain stimulation we can get really screws up our serotonin and neurotransmitter balance.  Maybe staying prolongly abstinent without ANY stimulation might prove advantageous.  Certainly I've never done that for 2 weeks.
 

Offline Dean93

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5714 on: 05/10/2009 21:07:02 »
Dean, is it me, or does that mustard seem to work?

I don't know GC, does it? No one that lives in my house really likes mustard, so all of the mustard we have is expired. I might try to get some from school, or they make turmeric in capsules. Did you take it in or out of POIS?

As an update, after twelve more POIS free days, today, I don't feel so great. Yesterday, there was no orgasm, just a particular conversation. I don't really see a point in going into detail, but for the sake of clarity and for the sake of the record, I will. I had a conversation with someone that I haven't talked to in almost a year. We had talked a lot in the past, to the point where this person became quite attached to me, while I had always found this person to be very immature. When she asked me why we didn't talk anymore, I didn't know what to say to her. I didn't want to tell her that she was just really immature, because I didn't want to hurt her feelings.

At that moment, I felt like my will was taken from me, as well as my energy. There was no orgasm, but how I feel today feels a lot like POIS. This completely confuses me. Perhaps it was my feeling that I could not express myself, or maybe it reminded me, subconsciously, of POIS, because I could hold a conversation with her in POIS...because it was so simple. I really don't know. I have no clue. I really don't like the fact that these symptoms come from anything other than orgasm, it makes it so much harder to control. This instance makes it seem like everything is all in my head...and I don't know. I try to ignore these things but, I don't know, its just so weird. I'm trying to find a way to moderate this thing and it seems every new episode is different than the last...I just really don't know. I'm getting the idea that orgasm is just one way to trigger these symptoms, and is not exactly THE direct cause. I have never been more confused about my POIS than today though. This just seems unheard of. Any relating stories would be appreciated, although I have doubts.

This is just so random, things were going so well...

Otherwise:

I'm debating whether to just wait this one out, or to just have an orgasm to "restart the cycle." In the past, I've always done a "restart", so this time I'll wait, to see if maybe it will resolve itself, perhaps taking a shorter amount of time. I'll wait a POIS duration, 17 days (the longest its been so far.)

Paulrx, can you elaborate on the whole prostate milking thing. It's been 22 days since I last had a release, and I'm feeling some pressure that doesn't feel too healthy.
« Last Edit: 05/10/2009 21:13:15 by Dean93 »
 

Offline GoingCrazy

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5715 on: 05/10/2009 22:35:44 »
Dean, I say that you wait it out too.  Right now I'm eating right and exercising, living a healthy life without any sexual stimulation.  And about the mustard, I just recently found out that I have the pill form of tumeric.  I probably just stated "does it work" because I probably was feeling quite well at the time.  I don't think tumeric is helping POIS, but it can be used for health at least.  I know all what you are going through, right now though I can hold conversations better in and out of POIS, maybe our bodies are in down production of neurotransmitters and health will get us back on track.  As time goes by, things are definitely improving for me.  Now my O's are just rediculous lasting rushes of adrenaline with headaches, no depression.  I think time will heal.

My parents also just ordered Lucidol for me (don't know if that spelling is correct), its supposed to basically be "brain food", and not a drug.  We'll see what happens once I take that.
« Last Edit: 05/10/2009 22:37:27 by goingcrazy »
 

Offline EDS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5716 on: 05/10/2009 23:03:51 »
Naps definately help  Unfortunately I don't sleep well that night if I nap, so I don't nap.

Question - does anyone get a runny nose after eating?

I found out my mother and aunt do which are similar symptoms of POIS.  I'm interested in knowing if you do to.  Google research shows a runny nose after eating is common but the cause is not known, nor the solution.  Some speculate a mild allergy to all food.  Could we have an allergy to O'ing?

LJ, sorry for the late reply, but yes I do get a runny nose after eating as well.
 

Offline EDS

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5717 on: 05/10/2009 23:05:22 »

Would anyone here be interested in my approaching a testosterone manufacturer (like Androderm/Watson Pharmaceuticals) to see if they would be interested in conducting research, clinical trials into the use of testosterone as a way to alleviate POIS - for low- testosterone and normal-testosterone POIS sufferers alike? Feel free to post your answer here or to send me a Private Message.

Count me in, Demo! I'm up for anything that may help us beat this thing!!

Just to let you guys know, I have been trying Androderm for a little over a month now (thanks Demo!). I have noticed some improvement, although I can say that it is only 30% - 40%, which I'll definitely take  :D I am using 5 mg patches which I think may not be enough. I think Demo is using 15 mg or maybe even higher now. I have not been retested yet, so I don't know how much my "number" has changed, but at this point I'm not sure the "number" is that important as long as it makes us feel better.

I'll keep you posted.
« Last Edit: 05/10/2009 23:46:21 by EDS »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5718 on: 06/10/2009 05:52:36 »

Would anyone here be interested in my approaching a testosterone manufacturer (like Androderm/Watson Pharmaceuticals) to see if they would be interested in conducting research, clinical trials into the use of testosterone as a way to alleviate POIS - for low- testosterone and normal-testosterone POIS sufferers alike? Feel free to post your answer here or to send me a Private Message.

Count me in, Demo! I'm up for anything that may help us beat this thing!!

Just to let you guys know, I have been trying Androderm for a little over a month now (thanks Demo!). I have noticed some improvement, although I can say that it is only 30% - 40%, which I'll definitely take  :D I am using 5 mg patches which I think may not be enough. I think Demo is using 15 mg or maybe even higher now. I have not been retested yet, so I don't know how much my "number" has changed, but at this point I'm not sure the "number" is that important as long as it makes us feel better.

I'll keep you posted.


EDS, great to hear! Congratulations!

I'm now steadily at 90%+ POIS-free.

I increased Androderm to 15mg. daily (with endocrinologist approval). And I double up on Adderall (with psychiatrist's approval)on Day Zero of POIS. That plus switching from passive behavior to active behavior (I force myself!) on Day Zero does the trick.

For a number of reasons, I have a hunch that some of us (including me) can benefit from treating POIS with "more testosterone than our minimum requirement". This would include people who test "normal" for testosterone.

But this is far from proven! So please don't anyone act on it!
« Last Edit: 06/10/2009 09:50:37 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5719 on: 06/10/2009 06:12:24 »

I just really don't know. I'm getting the idea that orgasm is just one way to trigger these symptoms, and is not exactly THE direct cause. I have never been more confused about my POIS than today though. This just seems unheard of. Any relating stories would be appreciated, although I have doubts.

This is just so random, things were going so well...


Dean, don't despair. For one thing, you're under physical pressure from a major physical and psychological change due to abstinence. Personally, I get pretty "crazy" from that. Some of the symptoms are POIS-like for me.

I just about stopped traveling some years back due to jet lag symptoms that were way beyond normal. Not exactly POIS, but close enough.

Same thing with alcohol, even moderate amounts. Again, not exactly POIS, but close enough.

SOMETHING in our system's gone haywire. Hormones? Neurotransmitters? We'll find out when we get studied.

I would guess that your POIS symptoms might happen elsewhere, but you can bet on them like clockwork when it's after climax.

Hang in there, Dean. We ARE making progress.
« Last Edit: 06/10/2009 06:16:58 by demografx »
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5720 on: 06/10/2009 06:23:11 »

I kept on researching POIS a bit more lately and I was wondering... how many of you have you been experiencing visual snow and tinnitus (intense and / or persistent ear buzzing) during the peak period of POIS symptoms?


Thanks, devastated, didn't know about visual snow, but here are some forum posts which included some discussion about tinnitus:
http://www.google.com/search?hl=en&q=tinnitus+POIS+site%3Ahttp%3A%2F%2Fthenakedscientists.com&aq=f&oq=&aqi=
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5721 on: 06/10/2009 08:24:42 »

Isn't that [testosterone use] why body builders have smaller testicles?


And you know this how?  :)

From word of mouth and several teachers and partly experience. You use testosterone without having deficiency your body starts to shut down its operation. 
When i used dhea( without guidiance i will say i noticed shrinkage in my testicles) not the same as testosterone but the precursor. 


CC, my endocrinologist agrees with you. I emailed him and he replied, "Too much testosterone may significantly decrease testes size. Replacement doses will not."

So thankfully I'm not in for shrinkage probs!
 

Offline Paulrx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5722 on: 06/10/2009 08:39:33 »
Thank you for the warm welcome, demografx.
I do not suffer from POIS, but my partner does. I'm gay. I'm the one who found out this was what he was suffering from.

Has anyone tried taking anti-prolactin drugs to see if it can prevent or cure POIS?
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5723 on: 06/10/2009 09:18:28 »

It's been 22 days since I last had a release, and I'm feeling some pressure that doesn't feel too healthy.


What is your average length of abstinence?
 

Offline demografx

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Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5724 on: 06/10/2009 09:26:52 »

Thank you for the warm welcome, demografx.
I do not suffer from POIS, but my partner does. I'm gay. I'm the one who found out this was what he was suffering from.

Has anyone tried taking anti-prolactin drugs to see if it can prevent or cure POIS?


You're welcome, Paulrx.

Another member is considering testing the anti-prolactin drug, bromocriptine, for POIS in the future.

I considered taking it for my hyperprolactinemia (hp, high prolactin) but I was told that it's not a benign agent. I cured myself of hp by reading up on it and quitting reglan, with my endocrinologist's blessing.

My prolactin count finally went from 90 to 9!

Prolactin in men is not yet well understood at all.
« Last Edit: 06/10/2009 09:37:38 by demografx »
 

The Naked Scientists Forum

Re: Post Orgasmic Illness Syndrome (POIS)
« Reply #5724 on: 06/10/2009 09:26:52 »

 

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