The Naked Scientists

The Naked Scientists Forum

Author Topic: How are cyanides detected in autopsy?  (Read 378 times)

Offline thedoc

  • Forum Admin
  • Administrator
  • Sr. Member
  • *****
  • Posts: 511
  • Thanked: 11 times
    • View Profile
How are cyanides detected in autopsy?
« on: 15/08/2016 14:23:02 »
Satith Naidu  asked the Naked Scientists:
   20 castor beans outer shell is removed and mashed and mixed with DMSO and the solution is spread on hand for just 1 minute.
What then happens?
If potasium cyanide is mixed with DMSO and spread on skin then what is the reaction.
what are the LD50 of above through skin.
How are they detected in autopsy?
Thanks!

   
What do you think?
« Last Edit: 15/08/2016 14:23:02 by _system »


 

Online exothermic

  • Sr. Member
  • ****
  • Posts: 481
  • Thanked: 22 times
    • View Profile
Re: How are cyanides detected in autopsy?
« Reply #1 on: 16/08/2016 01:05:29 »
Quote from: Satith Naidu
If potasium cyanide is mixed with DMSO and spread on skin then what is the reaction.

Rapid, systemic release of the cyanide anion through the skin.


Quote from: Satith Naidu
what are the LD50 of above through skin.

The LD50 for KCN via dermal exposure is 100 mg/kg with very high skin permeability and substantial absorption characterised by a permeability constant of 3.5X10-4 cm/h. What the LD50 is for KCN in DSMO solution, I have no idea.... but it's definitely far less.


Quote from: Satith Naidu
How are they detected in autopsy?

Via gas or liquid chromatography/mass-spectrometry e.g. CI-GC-MS/HPLC-MS/HS-GC.

~
 

The Naked Scientists Forum

Re: How are cyanides detected in autopsy?
« Reply #1 on: 16/08/2016 01:05:29 »

 

SMF 2.0.10 | SMF © 2015, Simple Machines
SMFAds for Free Forums