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Author Topic: Blood Groups......why ?..and general organ compatibility questions !  (Read 7961 times)

Offline neilep

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Hello,

Ewe Ok ?..good !..I appreciate the chat !

Here's some blood:



Nice isn't it ?...notice how happy it is just sitting there waiting to be transferred into someone who needs it ?

But, only someone who has the same type of blood is on it's acceptable use list !!

So, why do we have different blood types ?

Is this compatibility transfered to organs too or is organ compatibility not related to blood groups ?


Thanks



 

Offline kdlynn

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i think i asked this... but i can't find it and don't remember
 

Offline neilep

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i think i asked this... but i can't find it and don't remember

Did ewe ?..my apologies....perhaps ewe asked at a time when I was absent !..oh well..I hereby declare this thread a shared thread with kadie too !
 

Offline kdlynn

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oh how lovely. thank you, sir
 

Offline neilep

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oh how lovely. thank you, sir

We're obtaining ZERO response kadie !!.....*le sulk*
 

Offline Karen W.

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Hello,

Ewe Ok ?..good !..I appreciate the chat !

Here's some blood:



Nice isn't it ?...notice how happy it is just sitting there waiting to be transferred into someone who needs it ?

But, only someone who has the same type of blood is on it's acceptable use list !!

So, why do we have different blood types ?

Is this compatibility transfered to organs too or is organ compatibility not related to blood groups ?


Thanks



I must have weird blood as mine is not red like that it is almost black.. with a red tinge.. LOL it looks redder when it is bleeding but darker then that even. The Vampire told me it is common for people with little excercise and less oxygenation of the blood.

I believe blood type tissue etc etc all have to do with organ transplants as they try to match as much as possible .. there will already be anti rejection medication, but I believe that is true of most any transplant.. Surely blood type is a must in order to find a viable organ! It takes a long time to find a match especially if you are of rare blood type!
 

Offline dkv

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Compatibity gets expressed in various ways. Biologically it can mean different blood groups or different genes etc..
But from the point of TSP it is expected that similar life entities will tend to be behave similarly and will have less communication problems. Therefore the learning period will be small to engage in TSP.
As against this if the two dissimilar things(which are less similar) are brought together then it requires greater amount of time to learn to cooperate...(learning can be reflexive as well) But during the transition period or learning period the biological system must take decisions and really fast .. which is not possible in case of dissimilar life entities. Resulting in overshoot or undershoot of response to the stumuli(internal or external) creating the butterfly effect and collapsing the whole system.
Sometimes it can be avoided if the change is drastic and/or under supervision of doctors.
Heart transplant , kidney transplant , blood transfusion , or liver transplant etc are subjected to the same logic as used above.
A simple analogy can help you understand - in an english company appoint a frenc ceo.
 

Offline Carol-A

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Well, we have different blood groups because of small changes over evolutionary time. The ABO gene is on Chromosome 9, and it is tiny differences that make the difference between the groups. All three genes (ABO) and therefore the 4 blood groups (A, B, AB, and O) have been maintained because each offers some advantage. AB blood group is almost immune to Cholera, and A is somewhat immune, and so this offers an advantage, and O is maintained because is offers some resistance to Malaria (and perhaps some cancers). Natural selection is the key. If any of these were a disadvantage, it would have vanished over evolutionary time.
 

Offline dkv

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completely false statement.it turns out that  different blood groups are able to express apparent advantage of resistivity against some diseases.

There are thousands of diseases and going by the logic above there would have been thousands of blood groups.
A mere coincidence can not called Natural selection.

The reason behind diversity of blood group is same as the reason behind division of cell.
Let us take lines on the palm of hand .. no two person have same number of lines. BUT they can be classified on the basis  of overall characteristics..
This differentiation exist for each  life form in the memory of time as each one of them tried to reinforce itself.. A life entity tends to become as unique as possible. 
Diversity is the result if the similar charateristics try to come together or reinforce themselves for sexual pleasure.. This process results is seperation as well but these seperated one which are not less priveledged and contribute to the whole bionomics.
 

Offline Carol-A

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I am sorry, but this reply (dkv) is just ignorant.  Having read your cell idea, I can see why you are so mistaken::)
« Last Edit: 20/09/2007 16:38:01 by Carol-A »
 

Offline WylieE

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For organ compatibility not only do you have to account for the ABO types like Carol said- which produce carbohydrates on the surface of the cells, but you also have to make sure that the organ recipient doesn't have antibodies against the proteins either. 

Each of us has a nearly unique protein signature on our cells that allow our immune systems to identify cells that belong from foreign invading cells.  These proteins are called Human leukocyte antigens or HLAs and they decorate the outside of nucleated cells.  There are six specific antigens that are tested for in organ transplants.  Related people would have the best chance of being a match, and identical twins would be perfect matches.  I think if a perfect match is not found in some organ transplant cases you can get by with 5/6 matching depending on which of the 5 match.   

So for organ compatibility not only do you have to have the correct blood type - the ABO Carol was talking about but also the correct HLA type. 

This is especially critical for bone marrow transplants because the bone marrow is what produces the cells for the immune system.  So if you introduce a new immune system and it does not match up it will start attacking the receiver's body.
 

Offline that mad man

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Thanks WylieE, didn't know about the 6 antigens.

Last year my brother was diagnosed with bone cancer and the siblings were tested to try and find a donor match.

We were told the chances of a match in the siblings was 1 in 4. Well, I come from a family of 8 siblings and 2 matched, myself and my sister. I was expecting that the procedure would be a typical marrow transplant but its not like that now. The donor has a weeks course of injections that stimulate the bone marrow production. Blood is then taken, filtered and cells extracted which are then stored and given to recipient after their final dose of chemotherapy. 

It took over 6 week to get the test results as they also have to test for other things such as viruses.

Unfortunatly I could not be the donor as I carry the cytomegalovirus, a common childhood virus wh ich can be fatal to a compromised immune system. Glad to say my sister did not have it and did the transplant which was a success.

I'll have to look at the information pack as I'm sure it mentions they extract stem cells.

Bee
 

Offline neilep

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THANKING EWE ALL FOR YOUR WONDERFUL POSTS

HUGS EWE ALL..Mwah mwah mwah !

hugs and shmishes !!



Oh..and Bee !!..that's fantastic news about your brother !!
 

Offline Karen W.

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That really is fantastic.. Good luck to him!
 

Offline WylieE

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Wow,
That's really interesting, I have read about how hard it is to find a donor, how much effort is it on the donor's part?  Did your sister have to go through a lot of treatment before the surgery also?
I'm glad it was a success story!
 

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