How does liver disease lead to cirrhosis?

06 December 2009

Question

How does liver disease lead to cirrhosis?

Answer

We put this to Graeme Alexander:Graeme - The liver cells are part of a complicated organ - the liver - where there's lots of different types of cells. There's another cell sitting next to the liver cell called a stellate cell and there are signals sent out by an injured liver cell to those stellate cells which scar the liver. So the liver ends up being scarred in exactly the same way as someone who's had an operation and there's a scar on their skin, but this scar is spread finely and diffusely throughout the whole liver.

Add a comment