Naked Science Forum
Life Sciences => Physiology & Medicine => Topic started by: smart on 16/02/2018 10:08:54
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How exactly dopamine neurons in the hypothalamus may control penile erection and does erectile dysfunction (ED) is evidence of dopamine-mediated impairment? https://www.ncbi.nlm.nih.gov/pubmed/20128851
What do you think?
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Erectile dysfunction can be caused by many poisons, (lack of) physical condition, circulatory problems, hormonal, emotional and drug-affected states.
I am sure that Oxytocin plays a major part in bonding, as does dopamine and the hypothamus.
See: https://en.wikipedia.org/wiki/Erectile_dysfunction
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These pathways can be induced unconsciously and consciously. Getting an erection at the sight of a pretty girl is based on the unconscious. Masturbation is based on using the imagination to trigger these same pathways. An imagination pathway can be triggered by the unconscious mind. Once it becomes a routine pathway based on choice, this is based on conscious choice.
An observation I made years ago is, why isn't female lubrication dysfunction treated the same way as male erectile dysfunction? Both have similar brain origins; hypothalamus. Both could be limiting factors for sex.
For the female, not naturally lubricating, may be due to not being in the mood. She can't or does not wish to concentrate on the task at hand. It is easier to use lube; fast topical relief from female lubrication dysfunction, and wait for the physical sexual interaction with her mate, to trigger her natural lubrication. Maybe some men need more attention, and not be expected to get an erection, so they can lead the temporary cure of female lubrication dysfunction. Men may lose the ability to play sex doctor all the time, and wish to be the patient.
This may sound mean, but it is a fact. A younger female makes it easier for the male penis to work. This is natural and connected to natural fertility and an unconscious mind connection to instinct. If a male is in a long term relationship, that last decades, he is not longer have sex with a young female, even of she was young and pretty when they started. There is diminishing returns in terms of external stimulus, as we get older.
The result is the male needs to depend, more and more, on imagination pathways, which can be trigged by long standing love. Men will eventually each the point, that females get to reach much sooner, without social stigmatism; genital dysfunction. One solution is to prescribe a college cheerleader, every now and then to get the unconscious mind back on line. Or you can take drugs with side affects. Or we can address female lubrication dysfunction, so the male does not always have play caretaker before sex with such women.
The best spontaneous sex is connected to the unconscious mind. The unconscious mind, is not about play, but about getting down to business; reproduction. High odds reproduction for the unconscious means fertile and/or fertile looking. Natural lubrication is an unconscious trigger. If the man has an older female, who is not as interested in sex; lubrication dysfunction, there is little unconscious hypothalamus potential for an erection. The imagination has to come more into play. Faking the brain with drugs, is not a natural pathway of the brain. It is a perfect money making pathway, since it is a bandaid that needs periodic free market replacement.
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... and, evan_au, don't forget the one thing none of us can escape, or correct ... age.
There have been some studies done many years ago that not only pointed at age as a major cause of ED, but they also provided a plausible evolutionary justification...
For a species to produce strong, healthy, vibrant offspring it is preferable for the male, and the female for that matter, to be of an age that would be considered "young". In an article by FOX News https://www.shadygrovefertility.com/blog/diagnosing-infertility/does-sperm-quality-really-decrease-as-men-age/ (https://www.shadygrovefertility.com/blog/diagnosing-infertility/does-sperm-quality-really-decrease-as-men-age/), the University of Otago announced that "a recent sperm-aging study (was compiled that included) 90 studies from more than 30 countries, scientists confirmed that there are “consistent age-related declines” in the quantity of semen, the health of sperm, and sperm’s ability to perform. While the research did not say at what specific age sperm starts declining, it mentioned that other studies have found consistent deterioration for certain sperm traits after men turn 35 or 40."
So, even evolution is out to get us as we age. >:(
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... and, evan_au, don't forget the one thing none of us can escape, or correct ... age.
There have been some studies done many years ago that not only pointed at age as a major cause of ED,
Age used to be thought the main factor, but as @evan_au points out there are other factors. A study reported in 2003 in Annals of Internal Medecine said:
“Men with a healthy lifestyle and no chronic disease had the lowest risk for erectile dysfunction; the greatest difference was seen for men aged 65-79. For instance, men who exercised at least three hours per week had a 30% lower risk for ED than those who exercised little. Obesity, smoking, and excessive TV watching were also associated with having a greater risk of erectile dysfuncrtion.”
Other studies have show similar results and a recent study in UK shows many 80 yr olds having an active sex life.
Keep it up folks.
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Most of the famous treatments of ED don't target the dopaminic pathways.
So, at best, dopamine may be involved in some cases of ED.