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On the Lighter Side => New Theories => Topic started by: ron123456 on 20/09/2018 19:32:21

Title: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 20/09/2018 19:32:21
Hello
Scientist Michael Ristow, in 2006, indicated from his chemical experiments with the respiratory enzyme frataxin, that cancer growth in tumors may be inhibited by increasing mitochondrial respiration instead of trying to suppress glycolysis/fermentation of cancer cells.  From his experiments, the cancer cells actually grew slower due to the increased percentage of respiration.
Can frataxin be replaced by a super pulsed near infrared beam scanning within the therapeutic window (650nm-1350nm), energizing the chromophores on the electron chain complex's respiratory enzyme Cytochrome C Oxidase (within the mitochondrial inner membrane) leading to acceleration of electron transfer reactions. "More electron transport necessarily leads to the increased production of ATP." This beam should go 4-5 inches and can scan around all the tumors similar to a catscan. Maybe this would eliminate the tumor penetration problem for chemo and radiation? ....more potential energy for the battery across this inner membrane...thx



Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: Bored chemist on 20/09/2018 20:59:06
Can frataxin be replaced by a super pulsed near infrared beam scanning within the therapeutic window (650nm-1350nm), energizing the chromophores on the electron chain complex's respiratory enzyme Cytochrome C Oxidase ...?

I doubt it.
Many cells (including healthy ones) have cytochromes in them.
So those would absorb light at much the same wavelengths as the cytochromes in the cancer cells.
So any light that could "energizing the chromophores on the electron chain complex's respiratory enzyme Cytochrome C Oxidase" would be absorbed by healthy cells before it got to the cancer.
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 20/09/2018 23:06:11
...makes sense...Thank you
Title: Phosphoresce IR Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 16/11/2018 19:04:41
Perhaps a specific near infrared dye can be introduced?.... Tumors may be inhibited by increasing mitochondrial respiration instead of trying to suppress glycolysis/fermentation of cancer cells!... This dye can near infrared phosphoresce in it's triplet state until appropriate required recharge excitation time and then repeat, etc...... Some heavy atomic molecules phosphoresce maybe 24 hours? ....Thx.....
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: Bored chemist on 17/11/2018 00:47:30
Perhaps a specific near infrared dye can be introduced?...
It's already done.
https://en.wikipedia.org/wiki/Photodynamic_therapy#Second_generation
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 20/11/2018 21:29:16
If the therapeutic window thru hemoglobin, water and melanin allows 650-1350nm infrared to get thru, then why does this COX (cytochrome C oxidase) wavelength get thru as well to support a device such as the Litecure  LCT1000 laser (680nm and 980nm) based on COX wavelengths of  600-900nm? This device supports deep osteoarthritis and works...... (previous response "So those would absorb light at much the same wavelengths as the cytochromes in the cancer cells.
So any light that could "energizing the chromophores on the electron chain complex's respiratory enzyme Cytochrome C Oxidase" would be absorbed by healthy cells before it got to the cancer."
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: Bored chemist on 20/11/2018 21:54:24

If the therapeutic window thru hemoglobin, water and melanin allows 650-1350nm infrared to get thru, then why does this COX (cytochrome C oxidase) wavelength get thru as well to support a device such as the Litecure  LCT1000 laser (680nm and 980nm) based on COX wavelengths of  600-900nm? This device supports deep osteoarthritis and works...... (previous response "So those would absorb light at much the same wavelengths as the cytochromes in the cancer cells.
So any light that could "energizing the chromophores on the electron chain complex's respiratory enzyme Cytochrome C Oxidase" would be absorbed by healthy cells before it got to the cancer."


Is there any independent evidence that the device works as described?
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 21/11/2018 04:53:35
Yes......I have been going to Mount Sinai Hospital in Toronto (Rehab and Wellbeing Centre) once every week faithfully since November 2012 (except for the summer months of June, July and August) for severe osteoarthritis of the left hip for laser treatment. I get a 10-12 minute session of 10W continuous wave. I don't know why this wavelength of 810nm (20% of beam) and 980nm (80% of beam) is getting by the other cytochrome C oxidase in normal cells and reaching the arthritic cells. I specified the wavelengths incorrectly above as 680nm and 980nm instead of the correct 810nm and 980nm. That is why I suggested a super pulsed laser which would go even deeper for tumors. The LCT1000 works on the same principle of increasing ATP production via respiration in the mitochondria by increasing electrons in the electron transport chain via COX.
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: Bored chemist on 21/11/2018 07:28:29
What's the reference intervention?
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 21/11/2018 11:18:34
The treatment has an accumulative affect and lasts about three months (over the summer). Without the treatment (by the end of August) I can hardly move and in pain. With the treatment (by the end of September) I'm back to normal walking and no pain.
Title: Re: Could near-infrared light be used to suppress tumour growth?
Post by: ron123456 on 21/11/2018 18:56:16
http://photobiology.info/Hamblin.html