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New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 11/01/2015 18:35:18 »

I should also add that my POIS episodes feel like a dramatic drop in dopamine (sharp loss of desire and joy in general and that I have compensated with prescription codeine, which is risky business since it can lead to addiction ... never to be taken for more than 3 days in a row but that tends to be my POIS episode duration).

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New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 11/01/2015 17:39:26 »

I have POIS and also a condition called Empty Sella Syndrome, which means that the pituitary gland is pressed flat in its cavity by Cranial Fluid that builds pressure due to an "incompetent diaphragm". This was revealed by a CT scan and I wonder if the compromised pituitary gland plays a role in POIS ? Has anyone else done a CT scan and found any irregularity with the pituitary gland ?
My headache gets much worse a day after orgasm or even hot sex (along with the other usual POIS symptoms).

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New Theories / Re: Post Orgasmic Illness Syndrome (POIS)

« on: 11/07/2014 18:15:13 »

Hello ... I have not posted here for ages and as far as I can tell there is nothing very new going on for our syndrome ...
There are some perhaps relevant thoughts about how "stress" debilitates many body functions on a cellular level ... see Sapolsky's great documentary about "self esteem stress" impacting weight gain (around the belly), artery sclerosis , depression, dopamin function etc.

For me it is clearly a dopamine collapse happening around 6 hours after an O and then symptoms lasts for about a week. Headache (frontal lobe), severe grumpiness (poor my lovely wife).  I was first introduced to this hang-over syndrome http://www.reuniting.info by Marnia Robinson who still has the best explanation for how nature has genetically programed us for gene diversity, by finding fault with our mates after orgasm and looking for a NEW mate (see the Coolidge Effect -- http://www.reuniting.info/science/coolidge_effect ). 
My feeling is that many more people experience some variety of this than us POISers but that they don't connect the dots. If the symptoms are delayed it is not easy to say that there is a connection unless you have been alerted to the possibility of it !  Others, like me, have enough head aches so that it does not stand out (unless you look for it). The grumpiness, the brain fog, the cold symptoms, back aches etc. can be the same lack of connection so it is disappearing in our general up and down character...
So dopamine (the desire hormone) ... it falls sharply after orgasm but for some it disappears from the scale and keeps going down in waves ... total dopamine loss which affects the brain in many negative ways -- depression, memory loss and loss of other functions. Marnia's alarm started me looking and got me to the POIS page and for me the connection is obvious -- not so for everybody. There are many who want to find an answer that can be handled by antibiotics or some other pill. Perhaps there is some such solution for some I have not found one. I have never found Dr. Waldingers allergy autoimmune theory convincing, that we should be allergic to our sperm or semen ...
There was hope in Marnia's recommendation to skip frequent orgasms and practice Karrezza but for me that lead to another very disappointing discovery: that even getting "horny" triggered the hang-over respons but in a milder form. Still headaches but perhaps less intense. So how to deal with massive dopamine loss ? One that works but is dangerous is aspirin+codeine ... the morphine takes care of the dopamine loss but if you take it for more than 3 days you are hooked ! So you have to be aware and stop looking for relief at the 3d day onward. Oh well ... this is where I am now :-(