Naked Science Forum

Life Sciences => Physiology & Medicine => COVID-19 => Topic started by: evan_au on 11/12/2020 21:19:44

Title: Which COVID-19 candidate vaccines have been abandoned, and why?
Post by: evan_au on 11/12/2020 21:19:44

This week, a COVID-19 vaccine candidate from University of Queensland (UQ) and vaccine maker CSL was abandoned, even though Phase 1 safety trials showed that it was safe, and produced a good immune response to the SARS-COV-2 virus.

The reason was that this vaccine (falsely) triggered a weak positive result in commonly-used HIV tests.
- This reduces the effectiveness of AIDS testing that is vital for maintaining public health (AIDS had caused a previous, slow-burn pandemic)
- The vaccine did not contain HIV virus particles, and could not cause AIDS

The false-positive HIV result came from a "clamp" protein used to hold the SARS-COV2 spike protein in the correct shape as part of the SARS-COV2 vaccine. This clamp protein was inspired by a well-studied protein in HIV.
- The researchers were aware of this possibility, and tested for it, and included it on the approval forms signed by the participants.
- Since there were other vaccines which have passed phase 3 trials, and are proven effective against SARS-COV2 virus, they decided to abandon the UQ/CSL vaccine.

See: https://www.abc.net.au/news/2020-12-11/how-the-uq-covid-19-vaccine-induces-false-positive-hiv-results/12975048

PS: Some people have doubt about the quality of the testing used for COVID-19 vaccines, or political pressure encouraging shortcuts. Examples of cases where the the decision has been made to abandon or modify a vaccine might improve public confidence in the process and the product.

Title: Re: Which COVID-19 candidate vaccines have been abandoned, and why?
Post by: Zer0 on 24/05/2021 17:38:18

https://www.bbc.com/news/world-europe-56744474

It says Denmark Abandons O.AZ!
(Blood Clots)


P.S. - At times i Wonder bout Efficacy & Efficiency.
(Please Do Not Misunderstand, I'm Not an Anti - Vaxerr. )

100 people...not vaccinated.
All get Covid19 positive.
50% Asymptomatic.
80% Stay at Home and Recover.
20% Need Hospitalisation.
10% ICU & Ventilators.
5% Succumb.

5% is 5 people out of the group.
If 5 people are Vaccinated, 90% Vaccination Efficacy & Efficiency, hence 4 people won't catch it & remaining 1 person would, but it would be really mild, almost Asymptomatic.

Why Do Not the Vaccinators Guarantee No Reinfection & No Death?
What Stops then from making such claims?
(I'm guessing it's the raw medical data that evidently states a different story. )