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Water and epigenetic changes result
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Water and epigenetic changes result
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Water and epigenetic changes result
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03/08/2017 13:16:46 »
The structure and activity of the DNA is dependent on water and the degree of hydration.If we were to remove all the water from a cell, nothing would work. If we added any other solvent as a replacement, still nothing works. Everything is tuned to water. Water provides a secondary source of free energy that makes the cell come alive.
Epigenetic changes, like methylation, is like adding a little bead of oil ; organic bead, along the DNA. This creates surface tension with interfacial water, which causes local water to increase potential. Now there is free energy in the local water needed for genetic change.
Stresses that impact the cell will also add potential to the water. The water then adds potential to the organics structures within the water. Equilibrium can result is changes like methylation.
The problem with this being obvious, is the overuse of the random assumption. We live in a quantum universe which means only certain states are allowed. The random assumption assumes there are odds for all states, albeit some have very small odds. This contradicts the quantum nature of the universe, which states that probability is either 1.0 or 0,0. Statistics is a tool that was developed to approximate quantum reality in complex system. This is why is it helpful but not always reliable. As an example, protein in water fold with exact folds; 1.0, and not average folds. This reflects the quantum nature of protein folding, and not a statistical nature of protein folding.
Let me explain the difference between quantum reality and the approximation tool that confuses epigenetics. If we took a five sided dice,and threw it a large number of times, all the sides will appear, with equals odds, over time. The dice is symmetrical in weight, with human convention defining each side as having a different face value. This is not natural but is manmade.
For example, in nature the hydrogen atoms has five distinct quantum energy levels. If the hydrogen atom was modeled accurately as a dice, it would have five sides, but each side would not only has a different face value, but each side would need to have a different weight since each requires different energy to appear. If the dealer threw the hydrogen atom dice the same each time, not all the sides will have the same odds of appearing, since each side is loaded differently or needs a certain energy to appear. Statistics tries to approximate this complex situation with averages; all side average the same weight, which is not how quantum reality works. However, when you deal with umpteen hydrogen atoms this approximation can be helpful.
In terms of water, the methylation is a quantum states that loads the genetic dice so it makes use of quantum principles and not casino averaging principles. We need to make sure everyone is aware statistics and random is a tool and not a statement of natural fact. However, it is such a widely used tool in biology and medicine it has become a prosthesis for the mind, with the cart; tool, leading the horse; mind. One is not allowed to think without a statistical cart leading. The cart can lead the horse successfully downhill, but it has problems leading uphill and around epigenetic corners. If the quantum horse leads, there is more flexibility to address this.
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Last Edit: 03/08/2017 13:31:23 by
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Re: Water and epigenetic changes result
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Reply #1 on:
04/08/2017 12:12:13 »
The main pitfall toward understanding the role of water in biology and epigenetic changes is connected to statistical assumptions. This pitfall makes logic and inference analysis seem alien.
The first evidence of probability theory was in about 1550. It was invented as a way to predict future outcomes in games and gambling. In order to make a profit, underwriters were in need of dependable guidelines by which a profit could be expected, while the gambler was interested in predicting the possibility of gain. Statistics is still about taking risks and making money. Since the house always needs to win over time, to stay in business, statistical studies can conflict yet still both be considered valid; house still wins. This is not reality, but casino science.
Modern application of statistics treats the various sciences like each is a game in the science casino. Life is not based on the rules of gambling but rather life is based on card counting and loaded dice. This is taboo in the science casino since the house may not always win.
For example, proteins fold with exact folds. Water loads these dice. This observation is over 50 years old and still cannot be explained with statistics since it implies a probability of 1.0. This data is ignored and not allowed to play in the science casino since it appears to cheat. Life is not a gamble, but continues to be modeled like it is.
The main reason life is not a gambling or gaming system, can be seen with the basic system or oil and water. If we mix oil and water, we will randomize this two component system. The mixing could be modeled wth statistics since there can be many outcomes. If we stop the blender, the once system will spontaneously go from a state of random/disorder, back toward a two layer order. Water and oil will phase always separate back into repeatable order. It is the same outcome each time, no matter how long we blend or to what degree of random we start with. The randomly agitated dice will correct themselves, so the dice will eventually fall on seen as though loaded.
Life in other solvents might be successfully modelled with statistics, since all other solvents tend to dissolve and randomize organics. But waster is unique in that it de-randomizes organics, to lower surface tension, so the results are logical and predictable; quantum states of life appear.
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Last Edit: 04/08/2017 12:17:22 by
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Re: Water and epigenetic changes result
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05/08/2017 13:50:02 »
Let me demonstrate how the science casinos make it harder to do rational science. This analysis is based on the water and oil affect.
Say I go to a science casino, and tell a professional statistical dealer to shuffle a deck of new cards that I brought, until the cards are randomized. In this case, the decl of cards is a beaker of oil and water. The dealer agitates these cards to randomize them.
After he is done and satisfied, he places the deck on the table. What starts to happen, before our eyes, are the cards begin to un-shuffle and reorganize themselves, all the way until the original new deck of cards, reappears. You can shuffle this trick deck again and again, but if you wait too long to deal, the cards will start to form an order. Now this is like dealing with a fixed deck. Statistics does not apply in the traditional sense since this is not random for long.
Would I be allowed to gamble in that casino with those cards? The answer is no, since the deck would appear to be part of a magic trick that can fix the cards. This will not be allowed in the casinos, since the house may lose. However, this is how water and organics work within life.
The original deck of water-oil cards, brought to the science casino of biology, was the observation, over 50 years ago of protein folding with exact folds. Statistics predicts randomize and average folds. They assumed thermal vibrations in the water, would shuffle this deck of cards to create randomization. But observation showed that the water and oil affect keeps ordering the deck back to new, before the dealer can finish dealing.
This observation is still not allowed to play at the casino, since the house has to win and this looks like cheating even though it has been experimentally verified continuously over the past 50 years. It appears like the game of science is rigged in the casinos. How many people were even taught this statistical exception in life, even though this should be stressed to open the mind to reason.
A better model for the cell is the cell is like that deck of cards that can reorder itself. Perturbations by the environment will try to shuffle the deck, with the deck always trying to going back toward order. The reason this is possible is connected to free energy, which is the sum of entropy and enthalpy. With water and organics the enthalpy is so strong, that structural entropy can lower; against the second law, and still allow the free energy of the system to be consistent with energy laws. The shuffled deck of cards can reorder itself because each card has built in enthalpy that can drive this forward. The hydrogen bonding of water is the key. This is such a strong secondary bonding force in the cell that other secondary forces that define 3-D shapes, has to play ball; proteins obey even in science casinos.
Epigenetic is connected to this magic deck of cards that s blackballed in science casinos.
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Last Edit: 05/08/2017 14:01:34 by
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