[demografx]

I remember having had very painful testis trauma several times when I was under 10. Sometimes when I biked I braked strongly I slide of the saddle and falled on the bike frame. Maybe this caused my POIS. This would be so dumb.

I wonder the same about the trauma of an undescended testicle (eventually corrected surgically).

Gap creation?

[Animus]

I agree with you, guys. I simply don't believe that something, produced in our own bodies and that is inside us all the time, can lead to an allergic reaction......just don't make any sense to me....

I believe in chemical or hormonal imbalance, due to the body's work to replace sperm. In few words, something(s) is(are) off the rails(of course....hehehe) in people suffering from POIS. Everyone have symptoms after orgasms, but "normal people" have balanced organisms that deal with those symptoms in a blink of an eye. We have just a retarded process compared to them.

Of course, we must figured out how to speed up the process...that's why we are here

I have always felt that my testosterone treatment speeds up the replenishment of sperm.

When I feel "full" more rapidly I have dramatically reduced my length of time suffering POIS.

In the past, before TRT, the replenishment was VERY slow. And POIS lasted an agonizing 4 days, compared to hours now.

Interesting- I also felt this way pretty strongly. That is was the replenishment of semen after ejaculation that caused the symptoms. But I'm holding out for dr.Waldinger's theory. And I'm going to just see if I can't get involved in his research somehow. It was great that he wrote he was interested in having a phone call to some members. does anyone know if that's going to happen?

[CertainlyPOIS]

it is quite possible that injections of semen could cause the type of antibodies that attack and kill sperm like which is common in vasectomy patients.  the sperm in the injections of semen could cause one to actually become sterile.

Yes, in this regard, check out this study, which discusses damage that can be caused by the injection of guinea pigs with their own sperm/testis:

http://www.reproduction-online.org/cgi/reprint/22/1/119.pdf

And, in the same regard, this article is somewhat scary!

http://ihealthbulletin.com/blog/2007/02/13/vasectomy-may-lead-to-dementia-from-autoimmune-brain-damage/

I am really worried now.  These are EXACTLY the types of cognitive symptoms I get.  I am sure this is autoimmune now. 

My only comfort is that we seem to recover from the aphasia; it is not chronic.  Maybe no 'permanent' damage is being done?

I think you're right now, semen could be mixing with blood somewhere along the way to ejaculation, causing this reaction. This also supports the 'subsequent ejaculation' recovery that we've sometimes noticed...

In respond to this message, i want to WARN EVERYBODY TO START REDUCING the frequency of their orgasms.
i have pretty much being in pois for the last two years because of NE and because of that i gave up on trying to control myself so i have been ejaculation however i felt. This last week i succeded in stoping NEs and that wierld pois feeling around the body is gone but not the BRAIN FOG.  I hope my pois just takes longer to dissapear and not that am doing permanent damage to my body.  
Is there a way to check out if brain neurons are still normal.

[Counterpoints]

It seems several people have developed POIS from trying enlargement pills....  See skewbald240

http://www.reuniting.info/node/2647

I wonder what is in these?

[Animus]

I've made copies of both papers, press releases, announcements, for my doctors. And I'm going in to see 2 of them this week to share the news of this study with them. I think it'll help to get the word out- and get awareness up. I'd encourage everyone to do the same!!

[demografx]

I agree with you, guys. I simply don't believe that something, produced in our own bodies and that is inside us all the time, can lead to an allergic reaction......just don't make any sense to me....

I believe in chemical or hormonal imbalance, due to the body's work to replace sperm. In few words, something(s) is(are) off the rails(of course....hehehe) in people suffering from POIS. Everyone have symptoms after orgasms, but "normal people" have balanced organisms that deal with those symptoms in a blink of an eye. We have just a retarded process compared to them.

Of course, we must figured out how to speed up the process...that's why we are here

I have always felt that my testosterone treatment speeds up the replenishment of sperm.

When I feel "full" more rapidly I have dramatically reduced my length of time suffering POIS.

In the past, before TRT, the replenishment was VERY slow. And POIS lasted an agonizing 4 days, compared to hours now.

Interesting- I also felt this way pretty strongly. That is was the replenishment of semen after ejaculation that caused the symptoms. But I'm holding out for dr.Waldinger's theory. And I'm going to just see if I can't get involved in his research somehow. It was great that he wrote he was interested in having a phone call to some members. does anyone know if that's going to happen?

Animus, he said it will be done, but we need to be patient. Without funding, the individualized phone calls I imagine would take place amongst all his other medical, teaching,  lecturing and research responsibilities.

But thankfully, we have a very competent scientific team.....committed to POIS!

[Counterpoints]

Is there a way to check out if brain neurons are still normal.

I have always thought functional imaging (e.g. fMRI) would be good for investigating POIS.  

I worry about permanent damage too.  We can take some comfort from anecdotes here on the forum.  There are people here on the forum with cases similar to mine, but they have suffered for much longer, and they still seem sharp.

I think it would be useful for Waldinger (or someone) to do thorough neuropsychiatric cognitive assessments of patients IN and OUT of POIS, so that we could see precisely what the cognitive problems are.  We will then have a more precise description of the problem, which in itself will be useful for understanding, but it will also be much easier to relate POIS to conditions we know more about.  This could lead to treatments.

[demografx]

I've made copies of both papers, press releases, announcements, for my doctors. And I'm going in to see 2 of them this week to share the news of this study with them. I think it'll help to get the word out- and get awareness up. I'd encourage everyone to do the same!! demo- can we share this article with our doctors? Is it public domain now? Let me know if it isn't, cause my appointment is Monday! thanks

I think the general rule is no mass distribution, posting on the internet is not permitted. Personal sharing is ok, TO MY UNDERSTANDING. This is only my limited understanding. Just keep in mind that there is normally a price to be paid to access it, and be responsible. Seems to me like you are very responsible with it.

[demografx]

Is there a way to check out if brain neurons are still normal.

I have always thought functional imaging (e.g. fMRI) would be good for investigating POIS.  

I worry about permanent damage too.  We can take some comfort from anecdotes here on the forum.  There are people here on the forum with cases similar to mine, but they have suffered for much longer, and they still seem sharp.

I think it would be useful for Waldinger (or someone) to do thorough neuropsychiatric cognitive assessments of patients IN and OUT of POIS, so that we could see precisely what the cognitive problems are.  We will then have a more precise description of the problem, which in itself will be useful for understanding, but it will also be much easier to relate POIS to conditions we know more about.  This could lead to treatments.

This is strictly subjective, but it feels, in-POIS, like I've "lost some memories, creativity, ideas, talent, etc.". But when I'm out-of-POIS, it...ALL COMES BACK!

Wish this could be investigated.

[Animus]

It seems several people have developed POIS from trying enlargement pills....  See skewbald240

http://www.reuniting.info/node/2647

I wonder what is in these?

The ones I took were called VigRX- they're a pill made out of a combination of herbal extracts. Apparently a pretty potent combination. They way they worked on me was to increase blood flow in the pubes and intensify orgasm.

BTW, thanks for finding that other "enlargement pill" POIS case. For the longest time I've been looking for someone else with that experience.

[Animus]

Is there a way to check out if brain neurons are still normal.

I have always thought functional imaging (e.g. fMRI) would be good for investigating POIS.  

I worry about permanent damage too.  We can take some comfort from anecdotes here on the forum.  There are people here on the forum with cases similar to mine, but they have suffered for much longer, and they still seem sharp.

I think it would be useful for Waldinger (or someone) to do thorough neuropsychiatric cognitive assessments of patients IN and OUT of POIS, so that we could see precisely what the cognitive problems are.  We will then have a more precise description of the problem, which in itself will be useful for understanding, but it will also be much easier to relate POIS to conditions we know more about.  This could lead to treatments.

This is strictly subjective, but it feels, in-POIS, like I've "lost some memories, creativity, ideas, talent, etc.". But when I'm out-of-POIS, it...ALL COMES BACK!

Wish this could be investigated.

that's the way it worked for me too. That my mental abilities come back fully when I'm out of POIS. But I should say, the POIS worsened my tendency toward depression and made it more severe- but it's treatable with medicine. My cognitive ability came back fully though.

[Animus]

I've made copies of both papers, press releases, announcements, for my doctors. And I'm going in to see 2 of them this week to share the news of this study with them. I think it'll help to get the word out- and get awareness up. I'd encourage everyone to do the same!! demo- can we share this article with our doctors? Is it public domain now? Let me know if it isn't, cause my appointment is Monday! thanks

I think the general rule is no mass distribution, posting on the internet is not permitted. Personal sharing is ok, TO MY UNDERSTANDING. This is only my limited understanding. Just keep in mind that there is normally a price to be paid to access it, and be responsible. Seems to me like you are very responsible with it.

OK, thanks

[demografx]

Is there a way to check out if brain neurons are still normal.

I have always thought functional imaging (e.g. fMRI) would be good for investigating POIS.  

I worry about permanent damage too.  We can take some comfort from anecdotes here on the forum.  There are people here on the forum with cases similar to mine, but they have suffered for much longer, and they still seem sharp.

I think it would be useful for Waldinger (or someone) to do thorough neuropsychiatric cognitive assessments of patients IN and OUT of POIS, so that we could see precisely what the cognitive problems are.  We will then have a more precise description of the problem, which in itself will be useful for understanding, but it will also be much easier to relate POIS to conditions we know more about.  This could lead to treatments.

This is strictly subjective, but it feels, in-POIS, like I've "lost some memories, creativity, ideas, talent, etc.". But when I'm out-of-POIS, it...ALL COMES BACK!

Wish this could be investigated.

that's the way it worked for me too. That my mental abilities come back fully when I'm out of POIS. But I should say, the POIS worsened my tendency toward depression and made it more severe- but it's treatable with medicine. My cognitive ability came back fully though.

Same here!

[Counterpoints]

Well, one can easily investigate the (short term) cognitive changes in and out of POIS.  There are lots of carefully formulated assessments for doing something like this.  Standard neuropsych evaluations.  I would guess these are also used for making diagnoses.  I hope to see them in the next POIS study.

[Limejuice]

it is quite possible that injections of semen could cause the type of antibodies that attack and kill sperm like which is common in vasectomy patients.  the sperm in the injections of semen could cause one to actually become sterile.

Yes, in this regard, check out this study, which discusses damage that can be caused by the injection of guinea pigs with their own sperm/testis:

http://www.reproduction-online.org/cgi/reprint/22/1/119.pdf

And, in the same regard, this article is somewhat scary!

http://ihealthbulletin.com/blog/2007/02/13/vasectomy-may-lead-to-dementia-from-autoimmune-brain-damage/

I am really worried now.  These are EXACTLY the types of cognitive symptoms I get.  I am sure this is autoimmune now. 

My only comfort is that we seem to recover from the aphasia; it is not chronic.  Maybe no 'permanent' damage is being done?

I think you're right now, semen could be mixing with blood somewhere along the way to ejaculation, causing this reaction. This also supports the 'subsequent ejaculation' recovery that we've sometimes noticed...

These are my symptoms as well.

[CertainlyPOIS]

Is there a way to check out if brain neurons are still normal.

I have always thought functional imaging (e.g. fMRI) would be good for investigating POIS.  

I worry about permanent damage too.  We can take some comfort from anecdotes here on the forum.  There are people here on the forum with cases similar to mine, but they have suffered for much longer, and they still seem sharp.

I think it would be useful for Waldinger (or someone) to do thorough neuropsychiatric cognitive assessments of patients IN and OUT of POIS, so that we could see precisely what the cognitive problems are.  We will then have a more precise description of the problem, which in itself will be useful for understanding, but it will also be much easier to relate POIS to conditions we know more about.  This could lead to treatments.

This is strictly subjective, but it feels, in-POIS, like I've "lost some memories, creativity, ideas, talent, etc.". But when I'm out-of-POIS, it...ALL COMES BACK!

Wish this could be investigated.

that's the way it worked for me too. That my mental abilities come back fully when I'm out of POIS. But I should say, the POIS worsened my tendency toward depression and made it more severe- but it's treatable with medicine. My cognitive ability came back fully though.

I used to get all cognitive abilites back even when i went months without recovery but now that did not happen.
I remeber someone else talking about how they initially recover but takes them a while to get back to 100%. Hopefully that is what is happening.

[hurray]

I would like to express my thanks to Dr Waldinger for putting so much time and effort into his research into POIS. Without his help, we couldn't have got to where we are today - so many people have struggled to convince their doctors that POIS is real and potentially treatable. The new evidence that has been uncovered, as well as the worldwide publicity that it has generated, is a huge step towards help for us all. Thanks Dr Waldinger!

[POISon]

Hey everyone,I've been browsing this wonderful forum for about 6 months now and I am glad I found it.I used to think I must be the only one in the world with this cursed affliction until I found this forum.Its nice to know that there are others out there who want to eradicate POIS

I guess I'll tell a little about my POIS story.I'm 31 and have had this ailment since I was 21,so about 10 years.Its strange,I used to masturbate like crazy since I was 15 and only noticed symptoms 6 years later.My symptoms are heavy fatigue,feeling very spacy,irritable and sometimes mild to excessive anxiety.I v'e taking numerous traditional meds and alternative supplements and the the things that help me the most(at least for now) for my cognition and fatigue are the no sugar 5 Hour Energy brand drinks along with 30 mg zinc,sulbutiamine,and omega fish oil.

Like many people here my Pois symptoms are severely reduced after the 3rd or 4th day.For me after a week or so after orgasm I feel completely Pois free.AS many of you realize,its just so darn hard to go through life without eventually succumbing to masturbating or havingsex.Especially sex because then your making the significant other suffer too by depriving them of sex

I'm glad at least that POIS is starting to being taking serious enough now and thanks largely to this site for creating awareness!Its absolutely amazing that this site isn't even 4 years old yet and the BBC and the Learning Channel want to have a Tv interview with members here.I don't think its too far fetched that as a result of this increasing awareness, more funding will be set aside for POIS studies so us suffers will eventually(hopefully very soon) either have a cure or a successful medical treatment to control symptoms.

[demografx]

POISon, welcome to the POIS thread of The Naked Science Forum!




Here are some POIS resources which may be helpful to you:


Our POIS Information Website, built by "mat780", is here:
http://sites.google.com/site/POISwebsite/

Please see "B_Jim"'s POIS Summary of All Cases, here as well as others on the Web. This includes remedies that we have tested, and results.
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg149009#msg149009

"Girlwind" has created an excellent POIS Video:

Our new POIS chatroom (realtime chat). Invite or visit another member(s) there, ANY TIME. We can all get to know each other better:
http://forums.delphiforums.com/POIS/chat


* Most recent POIS Research Studies, 2011 *

If you will send Prof. dr. Waldinger an e-mail, stating that you have read his message on the Forum, at http://www.thenakedscientists.com/forum/index.php?topic=6576.msg340138#msg340138 and that you are willing to fill in a questionnaire, he will send you the copies of both 2011 research articles by return through email. At a later date, he will send you the questionnaire which, after having filled in, you should send him back by e-mail.
His email:
prof.dr.waldinger.pois@gmail.com

Prof. dr. Marcel D. Waldinger's website:
http://www.post-orgasmic-illness-syndrome.com/en/index.html


First POIS Research Study, 2002

We have a copy of the first formal medical investigation on POIS by Prof. dr. Marcel D. Waldinger,MD,PhD, and Dr. Dave Schweitzer, MD.

  
Recent POIS Research Study, 2010

CASE REPORT
Postorgasm Illness Syndrome - A Spectrum of Illnesses
Jane Ashby, MRCP, and David Goldmeier, MRCP
http://www.thenakedscientists.com/forum/index.php?topic=6576.msg316781#msg316781


British Medical Journal Case Report, 2010

Case study by Dr. Selwyn Dexter of a patient with a headache-featured POIS symptom treated with progesterone/norethisterone.
http://casereports.bmj.com/content/2010/bcr.10.2009.2359.short?rss=1


There are a couple of ways to get any or all of the above 3 studies: (1) if you want a PDF copy, send me a Private Message (PM) with your regular email address (use "AT" instead of "@" ) and I'll send you back the PDF.

Or, if you prefer, (2) I can simply reply with a Private Message (no regular email needed) and provide you with a simple text version embedded in your PM.

To send a Private Message, click on "Messages" at the top of this page. At the Messages page, click on "New Message". From that point on, it works just like posting a message here, except that it only goes to the person(s) you designate.

Remember to put a quote around my name, i.e., "demografx".


New York Times article,

January 20, 2009
Mind
Sex and Depression: In the Brain, if Not the Mind
By RICHARD A. FRIEDMAN, M.D.
http://www.nytimes.com/2009/01/20/health/views/20mind.html?_r=1&scp=1&sq=friedman%20sexual%20January%2020&st=cse

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

In addition to serving our own informational interests, the resources listed above can be useful for you to show our credibility to the medical world - which often shows little understanding and is sometimes skeptical of our condition: POIS has scientific underpinnings and POIS is not "just another psychological problem" related to sex - to be treated by the psychiatric/psychotherapeutic community. All of this information can greatly help you to fight the immediate reaction of some doctors: so just tell them, "IT'S NOT 'ALL IN OUR HEADS'! "

Also, it can be helpful when dealing with medical professionals to point out the successful existence of our rapidly growing forum, which has already been referenced in respectable sources such as the Journal of Sexual Medicine (Dr. Waldinger's study), British Medical Journal and wikipedia:
http://en.wikipedia.org/wiki/Postorgasmic_illness_syndrome

For nearly 4 years, our POIS forum has attracted over 200 POIS sufferers worldwide who have posted here, research on an additional 200 sufferers elsewhere on the internet, plus nearly 1,000,000 page visits. Not bad for a rare malady!

[demografx]

POISon, this post will help you find information about POIS that we have already discussed, by tailoring a Google search to this forum:


SEARCH THE FORUM WITH GOOGLE

We have an overwhelming amount of data: almost 4 years' worth of posts (over  10,000 posts!) from 150+ Forum members, and an additional 150 POIS sufferers found elsewhere on the Internet by Member B_Jim.

In the Google search box, type
whatever-it-is-you're-interested-in-finding-out[space]POIS[space]site:http://thenakedscientists.com/

for example, I tried
nocturnal emission POIS site:http://thenakedscientists.com/

and 740 results came up for "nocturnal emission" within the Forum.

be careful with spaces (you can use them before the word "site") and no-spaces (everything after the word "site")

Google even provides you results with the Message# for each result. But Message #'s do change, so be patient and look for the approximate Message#.