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Complementary Medicine / Re: Does Cannabis oil Cure some cancers?
« on: 01/11/2019 14:37:48 »
The mechanism of action for THC's anticancer/antineoplastic properties is mediated through the pro-apoptotic ceramide/p8-regulated autophagy pathway. However in stark contrast to these documented anti-cancer benefits of THC, there is a flipside; The copresence of the heparin-binding protein midkine/neurite growth promoting factor-2 can actually [increase] malignancy and resistance to the antitumor action of THC through the inhibition of the thc-evoked autophagy-mediated cell-death pathway through the stimulation of anaplastic lymphoma kinase. THC can also upregulate the proliferation of cancer cells through increased expression of the epidermal growth factor receptor ligand amphiregulin, via stimulation of anaplastic lymphoma kinase.
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