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  4. Can cannabis replace aspirin in the management of cardiovascular disease?
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Can cannabis replace aspirin in the management of cardiovascular disease?

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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #60 on: 18/04/2017 14:38:45 »
Quote from: exothermic on 18/04/2017 13:58:11
You don't even know who would be in the at-risk category for daily aspirin intake!

Primary Aspirin Risk Factors:

High dose protocols, bleeding disorders, history of GI ulcers or upper GI pain, renal failure, thrombocytopenia, liver disease and patients undergoing dual antiplatelet therapy.
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #61 on: 21/04/2017 00:14:07 »
Quote
Aspirin intermittently is not harmful, but aspirin every day for 10, 20, 30 years deters the body's coping mechanisms and over long periods, something is bound to happen that requires the bodies normal versatility of responses

No.

Daily low-dose aspirin does not alter homeostasis to such a degree.
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #62 on: 21/04/2017 00:39:33 »
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Aspirin can inhibit the production of prostacyclin that dilates blood flow to the lung and prevents pulmonary hypertension.

rofl.....

Anticoagulation and Aspirin as a Treatment for PAH

https://pulmonaryhypertensionnews.com/social-clips/2016/10/14/anticoagulation-and-aspirin-as-a-treatment-for-pah/
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #63 on: 21/04/2017 01:55:57 »
Quote
it also inhibits prostacylin production that normally counteracts the action of thromboxane A2 to prevent stroke.

Yeah, that's why 160 mg of aspirin per-day is effective for the primary and secondary prevention of stroke and myocardial infarction.... right?


Aspirin to prevent heart attack and stroke: what's the right dose?
Am J Med. 2006 Mar;119(3):198-202.
Aspirin to prevent heart attack and stroke: what's the right dose?
Dalen JE1.

https://www.ncbi.nlm.nih.gov/pubmed/16490462
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #64 on: 21/04/2017 14:53:56 »
Quote from: tkadm30 on 17/04/2017 09:41:34
In fact, there are serious risks associated with the use of aspirin, including increased risk of bleeding in the stomach and brain

https://www.fda.gov/drugs/resourcesforyou/consumers/ucm390574.htm

Show me the collective subset of patient data demonstrating an increased risk for upper GI bleeding and/or intracranial hemorrhage induced by daily aspirin @ 81-160 milligrams per-day.

Your concerns are merely warranted in the context of high-dose intake, dual antiplatelet therapy, or in patients who are already at an increased risk.

~
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #65 on: 24/04/2017 13:48:28 »
Oh I forgot to mention.... GI bleeding induced by aspirin can be circumvented with the coadministration of a proton pump inhibitor.
« Last Edit: 24/04/2017 15:58:23 by exothermic »
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #66 on: 29/04/2017 12:16:44 »
Quote from: Bored chemist on 18/04/2017 11:59:27
The problem, IMHO isn't with the forum as a whole.


I disagree.... completely:


Quote from: exothermic
Do any of the people who supposedly ask these questions, ever respond?

It's almost as if these questions are just here as a topic of discussion and nothing else.

Quote from: evan_au
Chris receives many questions via email (many probably triggered by his phone-in question shows in various countries).

Most of these people won't have signed up for the forum, so Chris posts the question here on their behalf.
- The system sends them an email after a few days to tell them where to look for answers.
- If they want to progress the discussion, they may sign up and discuss it further.

Quote from: exothermic
Well virtually nobody signs up and continues any of these discussions. So these people take the time to ask all these questions.... only to never have them answered directly?

That doesn't make sense.

I get the impression that all of these questions have already been answered directly, and what you see posted on this forum are merely topics of discussion.

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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #67 on: 30/04/2017 14:30:15 »
Quote from: Chris
I'm in the process of tidying up our user database, and it would be very helpful to know if you still intend to participate in the future, and if you would like us to keep your registration open.

I came here to help people..... not to have pointless discussions about questions which have already been answered.

Just delete my account.

~



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Offline chris

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #68 on: 30/04/2017 16:12:35 »
I think you are missing an important point: by providing good quality answers to questions here you are helping millions of people, not just the person who asked the question. Take a look at the stats - thousands of people look at this forum every day and use it to guide them. So a conversation today might not involve the original questioner, but the content within that debate will influence many people for many years to come.

I think you for your input.
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Offline exothermic

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Re: Can cannabis replace aspirin in the management of cardiovascular disease?
« Reply #69 on: 01/05/2017 01:40:43 »
Quote from: chris on 30/04/2017 16:12:35
I think you are missing an important point: by providing good quality answers to questions here you are helping millions of people, not just the person who asked the question. Take a look at the stats - thousands of people look at this forum every day and use it to guide them. So a conversation today might not involve the original questioner, but the content within that debate will influence many people for many years to come.

That may be so, but most of the information discussed here is already available online.... but while we are discussing the topic of helping people, could you please let me know what answer was given to the author of the following question:

https://www.thenakedscientists.com/forum/index.php?topic=67069.0

There's no way he was given the correct information - so unless he reviewed the thread, and understood the following quote.... his son continues to needlessly suffer.

Quote from: exothermic on 27/06/2016 21:50:10
A baseless diagnosis of a disease with no treatment and no cure - following 3-years of failed attempts at eradicating a mycoplasma/rickettsia infection is flat out reprehensible.

Hopefully the author will look for another physician. His son shouldn't have to suffer as a result of treatment inadequacy and he certainly doesn't need to hear that he's stuck with a disease that can't be cured.... when all of his symptoms are [directly] attributed to his mycoplasma/rickettsia infection.


Apparently only the moderators have the right answers.

If my answers aren't good enough for the author asking the question, then why should I take the time out of my day to respond? -- This is a rhetorical question of course, as the answer is obvious.

~
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Tags: cannabis  / atherosclerosis  / aspirin  / endocannabinoids 
 

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